124 research outputs found
Interaction of Nucleosides and Related Compounds with Nucleic Acids as Indicated by the Change of Helix-Coil Transition Temperature
A series of compounds has been tested for effectiveness in lowering the melting temperature of poly A and of thymus DNA. The order of increasing activity was found to be: adonitol, methyl riboside (both negligible) < cyclohexanol < phenol, pyrimidine, uridine < cytidine, thymidine < purine, adenosine, inosine, deoxyguanosine < caffeine, coumarin, 2,6-dichloro-7-methylpurine. Urea was ineffective with poly A and only slightly effective with DNA. At a concentration of 0.3 M, purine lowered the Tm of DNA about 9°
The Role of the Environment in Chaotic Quantum Dynamics
We study how the interaction with an external incoherent environment induces
a crossover from quantum to classical behavior for a particle whose classical
motion is chaotic. Posing the problem in the semiclassical regime, we find that
noise produced by the bath coupling rather than dissipation is primarily
responsible for the dephasing that results in the ``classicalization'' of the
particle. We find that the bath directly alters the phase space structures that
signal the onset of classical chaos. This dephasing is shown to have a
semiclassical interpretation: the noise renders the interfering paths
indistinguishable and therefore incoherent. The noise is also shown to
contribute to the quantum inhibition of mixing by creating new paths that
interfere coherently.Comment: 10 pages RevTex. Three figures in Postscript as a uuencoded
compressed tar file have been submitted as wel
Decoherence, Chaos, and the Correspondence Principle
We present evidence that decoherence can produce a smooth
quantum-to-classical transition in nonlinear dynamical systems. High-resolution
tracking of quantum and classical evolutions reveals differences in expectation
values of corresponding observables. Solutions of master equations demonstrate
that decoherence destroys quantum interference in Wigner distributions and
washes out fine structure in classical distributions bringing the two closer
together. Correspondence between quantum and classical expectation values is
also re-established.Comment: 4 pages, 2 figures (color figures embedded at low resolution), uses
RevTeX plus macro (included). Phys. Rev. Lett. (in press
Properties of the binding sites for the sn-1 and sn-2 acyl chains on the phosphatidylinositol transfer protein from bovine brain
Suicide attempts and related factors in patients admitted to a general hospital: a ten-year cross-sectional study (1997-2007)
[Abstract] Background: Suicide and suicide attempts represent a severe problem for public health services. The aim of this study is to determine the socio-demographic and psychopathological variables associated with suicide attempts in the population admitted to a General Hospital.
Methods: An observational-descriptive study of patients admitted to the A CoruĂąa University Hospital (Spain) during the period 1997-2007, assessed by the Consultation and Liaison Psychiatric Unit. We include n = 5,234 admissions from 4,509 patients. Among these admissions, n = 361 (6.9%) were subsequent to a suicide attempt. Admissions arising from a suicide attempt were compared with admissions occurring due to other reasons.Multivariate generalised estimating equation logistic regression models were used to examine factors associated with suicide attempts.
Results: Adjusting by age, gender, educational level, cohabitation status, being employed or unemployed, the psychiatric diagnosis at the time of the interview and the information on previous suicide attempts, we found that the variables associated with the risk of a suicide attempt were: age, psychiatric diagnosis and previous suicide attempts. The risk of suicide attempts decreases with age (OR = 0.969). Psychiatric diagnosis was associated with a higher risk of suicide attempts, with the highest risk being found for Mood or Affective Disorders (OR = 7.49), followed by Personality Disorders (OR = 7.31), and Schizophrenia and Other Psychotic Disorders (OR = 5.03).The strongest single predictive factor for suicide attempts was a prior history of attempts (OR = 23.63).
Conclusions: Age, psychopathological diagnosis and previous suicide attempts are determinants of suicide attempts
Will emergency and surgical patients participate in and complete alcohol interventions? A systematic review
<p>Abstract</p> <p>Background</p> <p>In the everyday surgical life, staff may experience that patients with Alcohol Use Disorders (AUDs) seem reluctant to participate in alcohol intervention programs. The objective was therefore to assess acceptance of screening and intervention as well as adherence to the intervention program among emergency department (ED) and surgical patients with AUDs.</p> <p>Methods</p> <p>A systematic literature search was followed by extraction of acceptance and adherence rates in ED and surgical patients. Numbers needed to screen (NNS) were calculated. Subgroup analyses were carried out based on different study characteristics.</p> <p>Results</p> <p>The literature search revealed 33 relevant studies. Of these, 31 were randomized trials, 28 were conducted in EDs and 31 evaluated the effect of brief alcohol intervention. Follow-up was mainly conducted after six and/or twelve months.</p> <p>Four in five ED patients accepted alcohol screening and two in three accepted participation in intervention. In surgical patients, two in three accepted screening and the intervention acceptance rate was almost 100%. The adherence rate was above 60% for up to twelve months in both ED and surgical patients. The NNS to identify one eligible AUD patient and to get one eligible patient to accept participation in alcohol intervention varied from a few up to 70 patients.</p> <p>The rates did not differ between randomized and non-randomized trials, brief and intensive interventions or validated and self-reported alcohol consumption. Adherence rates were not affected by patients' group allocation and type of follow-up.</p> <p>Conclusions</p> <p>Most emergency and surgical patients with AUD accept participation in alcohol screening and interventions and complete the intervention program.</p
Licit and illicit substance use patterns among university students in Germany using cluster analysis
Residue Analysis, Direct Potentiometric Method for Chloride Ion Applied to Residues of Chlorinated Insecticides
The Stereochemistry of alpha-Oxidation of Fatty Acids in Plants. The Stereochemistry of Biosynthesis of Long-Chain 2-Hydroxyacids
Mode of interaction of β-hydroxydecanoyl thioester dehydrase with allenic acid derivatives
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