Migration and identity processes among first-generation British South Asians

There has been little scholarly attention to the identities and migratory experiences of first-generation British South Asians, especially from social psychologists. Drawing upon Identity Process Theory, this article examines the inter-relations between migration and identity processes among twenty first-generation British South Asians. The interview data were analysed using qualitative thematic analysis. Results suggested that migration was perceived as a means of enhancing identity and that following migration individuals acquired a ‘higher’ social status in the homeland. Moreover, the psychologically traumatic aspects of migration, such as the loss of community and ‘otherisation’ from one's ethnic ingroup, were outlined. It is argued that migration can have profound socio-psychological implications and that decades later it can continue to shape individuals' sense of self and their attachment to relevant social categories. Furthermore, migration has important outcomes for the extent and nature of British national identification as well one's relationship with the ethnic ‘homeland’

Hip hop desis : South Asian Americans, Blackness, and a Global Race Consciousness : [book review]

Non UBCUnreviewedOthe

Components of male gametophytic competition in Vigna unguiculata Walp

This article does not have an abstract

Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis

InhA is a well validated Mycobacterium tuberculosis (Mtb) target as evidenced by the clinical success of isoniazid. Translating enzyme inhibition to bacterial cidality by targeting the fatty acid substrate site of InhA remains a daunting challenge. The recent disclosure of a methyl-thiazole series demonstrates that bacterial cidality can be achieved with potent enzyme inhibition and appropriate physicochemical properties. In this study, we report the molecular mode of action of a lead methyl-thiazole, along with analogues with improved CYP inhibition profile. We have identified a novel mechanism of InhA inhibition characterized by a hitherto unreported “Y158-out” inhibitor-bound conformation of the protein that accommodates a neutrally charged “warhead”. An additional novel hydrophilic interaction with protein residue M98 allows the incorporation of favorable physicochemical properties for cellular activity. Notably, the methyl-thiazole prefers the NADH-bound form of the enzyme with a <i>K</i>_d of ∼13.7 nM, as against the NAD⁺-bound form of the enzyme