A Rare Case of an Intratonsillar Abscess

The case describes the anatomy and pathophysiology of the palatine tonsils and the development of intratonsillar abscess. The abscess can be caused by a suppurative focus that arises in acute tonsillitis when outward drainage is prevented, leading to pus accumulation in the tonsillar tissue. Dehydration or a history of peritonsillar abscess can also lead to intratonsillar abscess. The condition can be mistaken for tonsillolith or malignancy, such as lymphoma. A computed tomography (CT) scan is recommended for diagnosis, showing a low-density and ring enhancement. Aspiration using a large bore needle is the preferred mode of treatment, but if repeated aspirations fail, tonsillectomy may be necessary. Intratonsillar abscess is rare and so far only 29 cases have been reported.1 The differential diagnoses include lymphoma, which usually presents as unilateral enlargement of the tonsil, tonsillolith due to its appearance and peritonsillar abscess again due to the unilateral enlargement of the tonsil. This case is different as compared to other reported cases we did not do a CT scan as recommended by most of the studies (cost being a concern). Also, in this case, we resorted to surgery as the main modality unlike other cases wherein the surgeons opted to do an aspiration of the pus mainly keeping the intraoperative complications in mind

High Performance Software Reconfiguration in the Context of Distributed Systems and Interconnection Networks.

Designed algorithms that are useful for developing protocols and supporting tools for fault tolerance, dynamic load balancing, and distributing monitoring in loosely coupled multi-processor systems. Four efficient algorithms are developed to learn network topology and reconfigure distributed application programs in execution using the available tools for replication and process migration. The first algorithm provides techniques for transparent software reconfiguration based on process migration in the context of quadtree embeddings in Hypercubes. Our novel approach provides efficient reconfiguration for some classes of faults that may be identified easily. We provide a theoretical characterization to use graph matching, quadratic assignment, and a variety of branch and bound techniques to recover from general faults at run-time and maintain load balance. The second algorithm provides distributed recognition of articulation points, biconnected components, and bridges. Since the removal of an articulation point disconnects the network, knowledge about it may be used for selective replication. We have obtained the most efficient distributed algorithms with linear message complexity for the recognition of these properties. The third algorithm is an optimal linear message complexity distributed solution for recognizing graph planarity which is one of the most celebrated problems in graph theory and algorithm design. Recently, efficient shortest path algorithms are developed for planar graphs whose efficient recognition itself was left open. Our algorithm also leads to designing efficient distributed algorithm to recognize outer-planar graphs with applications in Hamiltonian path, shortest path routing and graph coloring. It is shown that efficient routing of information and distributing the stack needed for for planarity testing permit local computations leading to an efficient distributed algorithm. The fourth algorithm provides software redundancy techniques to provide fault tolerance to program structures. We consider the problem of mapping replicated program structures to provide efficient communication between modules in multiple replicas. We have obtained an optimal mapping of 2-replicated binary trees into hypercubes. For replication numbers greater than two, we provide efficient heuristic simulation results to provide efficient support for both \u27N-version programming\u27 and \u27Recovery block\u27 approaches for software replication

Pleomorphic Adenoma of the Hard Palate:A Multidisciplinary Approach

Pleomorphic adenoma is the most common salivary gland tumor accounting for 80% of all major salivary gland tumors. It is a benign salivary gland neoplasm that constitutes 3% to 10% of the neoplasms in the head and neck region.1 Salivary gland neoplasms represents less than 1% of all tumors. This article is being showcased as a special case due to the fact it was done at a Taluk Hospital and also because ENT and oromaxillofacial surgeons were involved during the surgery

Aerodynamic drag reduction by heat addition into the shock layer for a large angle blunt cone in hypersonic flow

Reduction in aerodynamic drag for a large angle blunt cone flying at hypersonic Mach number by heat addition into the shock layer is demonstrated in HST2 hypersonic shock tunnel. The heat addition is achieved by the exothermic reaction of chromium atoms ablated from the stagnation region of the chromium coated blunt cone with the atomic oxygen behind the shock wave. The measurements show about 47% reduction in the drag coefficient for a 60° apex angle blunt cone in a Mach 8 flow of 3.4 MJ/kg specific enthalpy. The reduction in drag is measured using the accelerometer based force balance system and the heat addition into the shock layer is identified by the surface mounted thin film heat flux gauges and the corresponding movement of the shock wave is visualized by schlieren pictures

Pharmacognostic evaluation of Achyranthes coynei: Leaf

AbstractAchyranthes coynei Sant., (Amaranthaceae) is a rare, medicinal shrub, endemic to India. The plant especially, leaves are used in treatment of various disorders by folk healers. It has been scientifically evaluated for its antimicrobial and antioxidant properties. Pharmacognostic studies have not been carried out so far in this plant. So, the present study was undertaken to evaluate pharmacognostic characters of leaf of A. coynei. The studies were carried out in terms of morphological, microscopic characters and physicochemical parameters using standard methods. Leaf size (15–23 × 7–10 cm) and petiole nature (pink above and green beneath) were the distinguishing morphological character observed in the present study. Transverse section of leaf and petiole showed presence of long, multi-cellular, warty trichomes with pointed apex and short, glandular trichomes with blunt apex on thick walled epidermis; conjoint, collateral closed, endarch vascular bundles; rosette crystals of calcium oxalate in ground tissue. Ash and extractive values, micro and macro elements and nutritive factors were estimated. Leaf powder showed fluorescence under the influence of different solvents. Preliminary phytochemical screening showed the presence of alkaloids, saponins and triterpenoids. High Performance Thin Layer Chromatorgraphic (HPTLC) analysis yielded eight bands in leaf extract. The study forms the first report on pharamcognostic characters for A. coynei, which could be useful for identification and authentication of the plant

Comparative HPTLC analysis of stem and leaf of Achyranthes coynei with Achyranthes aspera

Leaf and stem materials of Achyranthes coynei and Achyranthes aspera were used for HPTLC analysis. HPTLC plates were developed on n-hexane: ethyl acetate (5:1 v/v) solvent system. The densitometric profiles were evaluated to elucidate differences within and among the species. The Rf values and number of peaks obtained in densitrogram indicated chemical variation in the species. Although, both species had more or less equal number of peaks, their Rf values, %height and %area varied. Thus HPTLC analysis in absence of external standards, proved to be an informative tool for evaluating differences between these species and their parts

Microfluidic-assisted synthesis of metal—organic framework —alginate micro-particles for sustained drug delivery

Drug delivery systems (DDS) are continuously being explored since humans are facing more numerous complicated diseases than ever before. These systems can preserve the drug’s functionality and improve its efficacy until the drug is delivered to a specific site within the body. One of the least used materials for this purpose are metal—organic frameworks (MOFs). MOFs possess many properties, including their high surface area and the possibility for the addition of functional surface moieties, that make them ideal drug delivery vehicles. Such properties can be further improved by combining different materials (such as metals or ligands) and utilizing various synthesis techniques. In this work, the microfluidic technique is used to synthesize Zeolitic Imidazole Framework-67 (ZIF-67) containing cobalt ions as well as its bimetallic variant with cobalt and zinc as ZnZIF-67 to be subsequently loaded with diclofenac sodium and incorporated into sodium alginate beads for sustained drug delivery. This study shows the utilization of a microfluidic approach to synthesize MOF variants. Furthermore, these MOFs were incorporated into a biopolymer (sodium alginate) to produce a reliable DDS which can perform sustained drug releases for up to 6 days (for 90% of the full amount released), whereas MOFs without the biopolymer showed sudden release within the first day.Department of Science and Technology (DST), India | Ref. DST/BDTD/EAG/2019Department of Science and Technology (DST), India | Ref. DST/TDT/DDP-31/2021Vision Group for Science and Technology (VGST), India | Ref. VGST/K-FISTL1/GRD No. 1053/2021-22Jain University, Minor Project | Ref. JU/MRP/Uni/3/202