585 research outputs found

    Organic Lawn Care Case Studies on Home Turf

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    The consistent growth in certified organic farming and demand for organic foods has fostered a companion movement towards employing organic growing methods for land care. With the objective of evaluating the agronomic potential for organic land care, I conducted a case study on my property in Monroe, NJ following land disturbance from construction. After the site was remediated with deep tillage to alleviate compaction and amended with compost and limestone based on soil tests it was seeded in September 2009 with a mix of modern turf type Kentucky bluegrass cultivars. Once established, this lawn was attractive, competitive against most weeds, and performed well over the following six years under organic management. This lawn was mowed frequently with the clippings always returned so as to recycle nutrients in place. It remained attractive without fertilizer input. In 2014, another organic lawn study was established at my farm in Ringoes, NJ to evaluate several organic fertilizers. Observations from this second case study indicated that soil test P was a key factor for turf establishment. Experience with the organic lawn in Ringoes, when contrasted to the results in Monroe, suggested that rapid germination and establishment of a dense turf stand is very important to preventing weeds during establishment

    The strategic use of patents in standardization in relation to US, European and Chinese competition law

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    Technologies embedded in standards are most often protected by patents. This research shows that competition law concerns will be raised as soon as the standardization process is manipulated to enable patent holders to gain unfair competitive advantages. Strategic patenting has become common practice in the telecommunications industry. Substantial patent portfolios are used as “weapons of mass destruction” to fend off infringement cases by competitors. This study argues that patent pools are a possible solution to the aforementioned problems in the US, EU and China. Chinese firms may benefit from Western technology in standards that are cooperatively developed. Western companies would appreciate the increased legal certainty and the possibility of outsourcing more sophisticated forms of manufacturing to Chinese firms. Patent pools are a good alternative for the Chinese government and businesses to participate more in standards. A patent pool can facilitate a smoother and more efficient technology transfer for foreign companies in China, which would benefit all the relevant stakeholders, including the Chinese government

    Making Sense of the Epigenome Using Data Integration Approaches

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    Epigenetic research involves examining the mitotically heritable processes that regulate gene expression, independent of changes in the DNA sequence. Recent technical advances such as whole-genome bisulfite sequencing and affordable epigenomic array-based technologies, allow researchers to measure epigenetic profiles of large cohorts at a genome-wide level, generating comprehensive high-dimensional datasets that may contain important information for disease development and treatment opportunities. The epigenomic profile for a certain disease is often a result of the complex interplay between multiple genetic and environmental factors, which poses an enormous challenge to visualize and interpret these data. Furthermore, due to the dynamic nature of the epigenome, it is critical to determine causal relationships from the many correlated associations. In this review we provide an overview of recent data analysis approaches to integrate various omics layers to understand epigenetic mechanisms of complex diseases, such as obesity and cancer. We discuss the following topics: (i) advantages and limitations of major epigenetic profiling techniques, (ii) resources for standardization, annotation and harmonization of epigenetic data, and (iii) statistical methods and machine learning methods for establishing data-driven hypotheses of key regulatory mechanisms. Finally, we discuss the future directions for data integration that shall facilitate the discovery of epigenetic-based biomarkers and therapies.Peer reviewe

    Evidence for a Black Hole and Accretion Disk in the LINER NGC 4203

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    We present spectroscopic observations from the Hubble Space Telescope that reveal for the first time the presence of a broad pedestal of Balmer-line emission in the LINER galaxy NGC 4203. The emission-line profile is suggestive of a relativistic accretion disk, and is reminiscent of double-peaked transient Balmer emission observed in a handful of other LINERs. The very broad line emission thus constitutes clear qualitative evidence for a black hole, and spatially resolved narrow-line emission in NGC 4203 can be used to constrain its mass, with M_BH less than 6 x 10^6 solar masses at 99.7% confidence. This value implies a ratio of black-hole mass to bulge mass of less than approximately 7 x 10^-4 in NGC 4203, which is less by a factor of ~3 - 9 than the mean ratio obtained for other galaxies. The availability of an independent constraint on central black-hole mass makes NGC4203 an important testbed for probing the physics of weak active galactic nuclei. Assuming M_BH near the detection limit, the ratio of observed luminosity to the Eddington luminosity is approximately 10^-4. This value is consistent with advection-dominated accretion, and hence with scenarios in which an ion torus irradiates an outer accretion disk that produces the observed double-peaked line emission. Follow-up observations will make it possible to improve the black-hole mass estimate and study variability in the nuclear emission.Comment: 10 pages (LaTeX, AASTeX v4.0), 2 postscript figures, accepted for publication in The Astrophysical Journal Letter

    F-theory Compactifications for Supersymmetric GUTs

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    We construct a family of elliptically fibered Calabi-Yau four-folds Y_4 for F-theory compactifications that realize SU(5) GUTs in the low-energy limit. The three-fold base X_3 of these fibrations is almost Fano and satisfies the topological criteria required to ensure that the U(1)_Y gauge boson remains massless, while allowing a decoupling of GUT and Planck scale physics. We study generic features of these models and the ability to engineer three chiral generations of MSSM matter. Finally, we demonstrate that it is relatively easy to implement the topological conditions required to reproduce certain successful features of local F-theory models, such as the emergence of flavor hierarchies.Comment: 55 pages, 10 figure

    Barriers to the management of Heart Failure in Ontario Long-Term Care Homes: an Interprofessional Care perspective

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    Background: With population aging, the prevalence of heart failure (HF) is risingin long-term care (LTC) homes. Given this burden, there is an urgent need to establish effective HF management programs.Methods and Findings: To understand what barriers would need to be addressed to develop such a program, we conducted a series of consultations among various LTC staff, as well as residents and their family caregivers. This article uses data obtained from the consultations to describe the interprofessional (IP) barriers that exist among the various LTC staff roles. Consultation methods included a Delphi survey followed by focus group interviews of LTC staff, and then personal interviews with LTC residents with HF and their family caregivers. Data were interpreted using an IP care framework in which interpersonal relationships among LTC staff provide the most direct influence on collaborative resident-centred practice, within the broader context of conditions within the LTC home, which in turn are housed in the broader context of systemic determinants.Conclusion: Across all data sets, the most consistently mentioned determinant was communication between the resident and the healthcare team, between different healthcare providers, between shifts, between medical specialists, and between the long-term care home and the hospital

    STIS ultraviolet/optical spectroscopy of `warm' ultraluminous infrared galaxies

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    (Abridged) We present high spatial resolution ultraviolet and optical spectroscopy, obtained using the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope, of nuclear structures within four `warm' Ultraluminous Infrared Galaxies (ULIRGs). We find an AGN in at least three, and probably all four of our sample, hosted in a compact, optically luminous `knot'. In three cases these knots were previously identified as a putative AGN nucleus from multiband optical imaging. Three of the sample also harbor a starburst in one or more knots, suggesting that the optically luminous knots seen in local ULIRGs are the most likely sites of the dust-shrouded starburst and AGN activity that power the infrared emission. The four AGN have a diverse range of properties; two are classical narrow line AGN, one shows both broad and narrow lines and evidence for lines of sight from the narrow through to the broad line regions, and one is plausibly a FeLoBAL AGN. The probable presence in one object of an FeLoBAL AGN, which are extremely rare in the QSO population, supports the idea that LoBAL AGN may be youthful systems shrouded in gas and dust rather than AGN viewed along a certain line of sight. The three starbursts for which detailed constraints are possible show a smaller range in properties; all three bursts are young with two having ages of ~4Myr and the third having an age of 20Myr, suggesting that ULIRGs undergo several bursts of star formation during their lifetimes. None of the starbursts show evidence for Initial Mass Function slopes steeper than about 3.3. The metallicities of the knots for which metallicities can be derived are all at least 1.5 times the Solar value. The properties of one further starburst knot are consistent with it being the forming core of an elliptical galaxy.Comment: ApJ, accepte

    ROSAT PSPC observations of nearby spiral galaxies - II. Statistical properties

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    We present a statistical analysis of the largest X-ray survey of nearby spiral galaxies in which diffuse emission has been separated from discrete source contributions. Regression and rank-order correlation analyses are used to compare X-ray properties such as total, source and diffuse luminosities, and diffuse emission temperature, with a variety of physical and multi-wavelength properties, such as galaxy mass, type and activity, and optical and infrared luminosity. The results are discussed in terms of the way in which hot gas and discrete X-ray sources scale with the mass and activity of galaxies, and with the star formation rate. We find that the X-ray properties of starburst galaxies are dependent primarily on their star-forming activity, whilst for more quiescent galaxies, galaxy mass is the more important parameter. One of the most intriguing results is the tight linear scaling between far-infrared and diffuse X-ray luminosity across the sample, even though the hot gas changes from a hydrostatic corona to a free wind across the activity range sampled here.Comment: 13 pages, latex file, 18 postscript figures, to appear in MNRA

    LINER/H II "Transition" Nuclei and the Nature of NGC 4569

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    Motivated by the discovery of young, massive stars in the nuclei of some LINER/H II ``transition'' nuclei such as NGC 4569, we have computed photoionization models to determine whether some of these objects may be powered solely by young star clusters rather than by accretion-powered active nuclei. The models were calculated with the photoionization code CLOUDY, using evolving starburst continua generated by the the STARBURST99 code of Leitherer et al. (1999). We find that the models are able to reproduce the emission-line spectra of transition nuclei, but only for instantaneous bursts of solar or higher metallicity, and only for ages of ~3-5 Myr, the period when the extreme-ultraviolet continuum is dominated by emission from Wolf-Rayet stars. For clusters younger than 3 Myr or older than 6 Myr, and for models with a constant star-formation rate, the softer ionizing continuum results in an emission spectrum more typical of H II regions. This model predicts that Wolf-Rayet emission features should appear in the spectra of transition nuclei. While such features have not generally been detected to date, they could be revealed in observations having higher spatial resolution. Demographic arguments suggest that this starburst model may not apply to the majority of transition nuclei, particularly those in early-type host galaxies, but it could account for some members of the transition class in hosts of type Sa and later. The starburst models during the Wolf-Rayet-dominated phase can also reproduce the narrow-line spectra of some LINERs, but only under conditions of above-solar metallicity and only if high-density gas is present (n_e >~ 10^5 cm^{-3}). This scenario could be applicable to some ``Type 2'' LINERs which do not show any clear signs of nonstellar activity.Comment: To appear in PASP. 22 pages, includes 9 figures, uses AASTeX v5.
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