Real-time testing of the on-site warning algorithm in southern California and its performance during the July 29 2008 M_w5.4 Chino Hills earthquake

The real-time performance of the τ_c -P_d on-site early warning algorithm currently is being tested within the California Integrated Seismic Network (CISN). Since January 2007, the algorithm has detected 58 local earthquakes in southern California and Baja with moment magnitudes of 3.0 ≤ M_w ≤ 5.4. Combined with newly derived station corrections the algorithm allowed for rapid determination of moment magnitudes and Modified Mercalli Intensity (MMI) with uncertainties of ±0.5 and ±0.7 units, respectively. The majority of reporting delays ranged from 9 to 16 s. The largest event, the July 29 2008 M_w5.4 Chino Hills earthquake, triggered a total of 60 CISN stations in epicentral distances of up to 250 km. Magnitude predictions at these stations ranged from M_w4.4 to M_w6.5 with a median of M_w5.6. The closest station would have provided up to 6 s warning at Los Angeles City Hall, located 50 km to the west-northwest of Chino Hills

Static deformations from point forces and force couples located in welded elastic Poissonian half-spaces: Implications for seismic moment tensors

We present analytic expressions for the static deformations produced by point forces and point force couples embedded in two elastic Poissonian half-spaces that are welded on a horizontal interface. We show that the deformations from point forces and from vertically dipping strike-slip point double couples vary continuously (except at the strike-slip source) as the source is moved across the welded interface. We show that the pattern of deformations from vertically dipping (or horizontally dipping) dip-slip point double couples also vary continuously as the source is moved across the welded interface, but the amplitude of the deformations jumps by the ratio of the rigidities. Finally, we show that the pattern of deformation from a point explosion source or from a point double-couple source dipping at angles other than 0° or 90° jumps as the source is moved across the boundary. We demonstrate that integration of point double-couple sources on a plane of finite extent mimics the deformation of slip on a fault plane where the total moment of the double-couples is μAD. We also demonstrate that deformations from a distribution of double couples on a horizontally dipping finite plane just above the interface are indistinguishable from the deformations produced by a similar distribution of double couples located just below the interface but with a total moment that is different by the ratio of the rigidities. This demonstrates that the moment of a dislocation that occurs between two materials is ambiguously defined. We discuss reasons why seismic moment is not a very satisfying way to parameterize the size of an earthquake. We show that potency, defined to be the integral of the slip over the rupture surface, is a more natural size scaling parameter than seismic moment

BLITZEN: A highly integrated massively parallel machine

The architecture and VLSI design of a new massively parallel processing array chip are described. The BLITZEN processing element array chip, which contains 1.1 million transistors, serves as the basis for a highly integrated, miniaturized, high-performance, massively parallel machine that is currently under development. Each processing element has 1K bits of static RAM and performs bit-serial processing with functional elements for arithmetic, logic, and shifting

Leech Parasitism of the Gulf Coast Box Turtle, Terrapene carolina major (Testudines:Emydidae) in Mississippi, USA

Ten leeches were collected from a Gulf Coast box turtle, Terrapene carolina major, found crossing a road in Gulfport, Harrison County, Mississippi, USA. Eight of the leeches were identified as Placobdella multilineata and 2 were identified as Helobdella europaea. This represents the second vouchered report of leeches from a box turtle. Helobdella europaea is reported for the first time associated with a turtle and for the second time from the New World

A V-Diagram for the Design of Integrated Health Management for Unmanned Aerial Systems

Designing Integrated Vehicle Health Management (IVHM) for Unmanned Aerial Systems (UAS) is inherently complex. UAS are a system of systems (SoS) and IVHM is a product-service, thus the designer has to take into account many factors, such as: the design of the other systems of the UAS (e.g. engines, structure, communications), the split of functions between elements of the UAS, the intended operation/mission of the UAS, the cost verses benefit of monitoring a system/component/part, different techniques for monitoring the health of the UAS, optimizing the health of the fleet and not just the individual UAS, amongst others. The design of IVHM cannot sit alongside, or after, the design of UAS, but itself be integrated into the overall design to maximize IVHM’s potential. Many different methods exist to help design complex products and manage the process. One method used is the V-diagram which is based on three concepts: decomposition & definition; integration & testing; and verification & validation. This paper adapts the V-diagram so that it can be used for designing IVHM for UAS. The adapted v-diagram splits into different tracks for the different system elements of the UAS and responses to health states (decomposition and definition). These tracks are then combined into an overall IVHM provision for the UAS (integration and testing), which can be verified and validated. The stages of the adapted V-diagram can easily be aligned with the stages of the V-diagram being used to design the UAS bringing the design of the IVHM in step with the overall design process. The adapted V-diagram also allows the design IVHM for a UAS to be broken down in to smaller tasks which can be assigned to people/teams with the relevant competencies. The adapted V-diagram could also be used to design IVHM for other SoS and other vehicles or products

Understanding Teacher Leadership in Middle School Mathematics: A Collaborative Research Effort

We report findings from a collaborative research effort designed to examine how teachers act as leaders in their schools. We find that teachers educated by the Math in the Middle Institute act as key sources of advice for colleagues within their schools while drawing support from a network consisting of other teachers in the program and university-level advisors. In addition to reporting on our findings, we reflect on our research process, noting some of the practical challenges involved, as well as some of the benefits of collaboration

Studies in predictor display technique Final report

Predictor display technique for manual altitude control, and automatic pitch axis performanc

Nivolumab-induced fulminant diabetic ketoacidosis followed by thyroiditis

Five days following the 3rd cycle of nivolumab, a monoclonal antibody, which acts as immune checkpoint inhibitor against the programmed cell death protein-1, for metastatic lung adenocarcinoma, a 56-year-old woman presented at the hospital critically ill. On admission, she had severe diabetic ketoacidosis (DKA), as evidenced by venous glucose of 47 mmol/L, blood ketones of 7.5 mmol/L, pH of 6.95 and bicarbonate of 6.6 mmol/L. She has had no personal or family history of diabetes mellitus (DM), while random venous glucose, measured 1 week prior to hospitalisation, was 6.1 mmol/L. On admission, her HbA1c was 8.2% and anti-GAD antibodies were 12 kIU/L (0–5 kU/L), while islet cell antibodies and serum C-peptide were undetectable. Nivolumab was recommenced without the development of other immune-mediated phenomena until 6 months later, when she developed hypothyroidism with TSH 18 U/L and low free T4. She remains insulin dependent and has required levothyroxine replacement, while she has maintained good radiological and clinical response to immunotherapy. This case is notable for the rapidity of onset and profound nature of DKA at presentation, which occurred two months following commencement of immunotherapy. Despite the association of nivolumab with immune-mediated endocrinopathies, only a very small number of patients developing type 1 DM has been reported to date. Patients should be closely monitored for hyperglycaemia and thyroid dysfunction prior to and periodically during immunotherapy

Feasibility and initial efficacy of project-based treatment for people with ABI

Background: Communication impairments are common and pervasive for people a long time following acquired brain injury (ABI). These impairments have a significant impact on a person's quality of life (QOL) post‐injury. Project‐based treatment is a treatment approach that could have an impact on communication skills and QOL for people with ABI a long‐term post‐injury. This treatment is embedded in a context of meaningful activities chosen by people with ABI, whereby, as a group, they work collaboratively to achieve a tangible end product. Aims: To evaluate the feasibility and initial efficacy of project‐based treatment on improving the communication skills and QOL for people with ABI. Methods & Procedures: An exploratory controlled trial with alternate allocation of groups, and follow‐up at 6–8 weeks, was completed. Twenty‐one people with chronic ABI were recruited in groups of two to three from community settings, allocated to either a TREATMENT (n = 11) or WAITLIST group (n = 10). Participants attended a 20‐h group‐based treatment over 6 weeks where they worked towards achieving a project that helped others. To determine feasibility, four criteria were used: demand, implementation, practicality and acceptability. A range of communication and QOL outcomes was used to determine a fifth feasibility criterion, initial efficacy. Some of these criteria were additionally used to evaluate the feasibility of the outcomes. Outcomes & Results: All participants received the treatment as allocated with high attendance and no dropouts. The treatment was feasible to deliver as intended and was highly acceptable to participants. Medium and large effect sizes were found from pre‐ to post‐treatment, and from pre‐treatment to follow‐up for measures of conversation, perceived communicative ability and QOL. Conclusions & Implications: Project‐based treatment is feasible with indications of initial efficacy for both communication skills and QOL. The treatment provides a promising new approach for improving communication skills and QOL in people with chronic acquired brain injuries in the community setting

Combining Multiple Earthquake Models in Real Time for Earthquake Early Warning

The ultimate goal of earthquake early warning (EEW) is to provide local shaking information to users before the strong shaking from an earthquake reaches their location. This is accomplished by operating one or more real‐time analyses that attempt to predict shaking intensity, often by estimating the earthquake’s location and magnitude and then predicting the ground motion from that point source. Other EEW algorithms use finite rupture models or may directly estimate ground motion without first solving for an earthquake source. EEW performance could be improved if the information from these diverse and independent prediction models could be combined into one unified, ground‐motion prediction. In this article, we set the forecast shaking at each location as the common ground to combine all these predictions and introduce a Bayesian approach to creating better ground‐motion predictions. We also describe how this methodology could be used to build a new generation of EEW systems that provide optimal decisions customized for each user based on the user’s individual false‐alarm tolerance and the time necessary for that user to react