927 research outputs found

    15 years of comet photometry: A comparative analysis of 80 comets

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    In 1976 we began a program of narrowband photometry of comets that has encompassed well over 400 nights of observations. To date, the program has provided detailed information on 80 comets, 11 of which have been observed on multiple apparitions. In this paper we present the observed range of compositions (molecular production rate ratios) and dustiness (gas production compared with AF-rho) for a well sampled group of comets. Based on these results we present preliminary analysis of taxonomic groupings as well as the abundance ratios we associate with a 'typical' comet

    SRSF1 modulates the organization of splicing factors in nuclear speckles and regulates transcription

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    The mammalian cell nucleus is compartmentalized into non-membranous subnuclear domains that regulate key nuclear functions. Nuclear speckles are subnuclear domains that contain pre-mRNA processing factors and non-coding RNAs. Many of the nuclear speckle constituents work in concert to coordinate multiple steps of gene expression, including transcription, pre-mRNA processing and mRNA transport. The mechanism that regulates the formation and maintenance of nuclear speckles in the interphase nucleus is poorly understood. In the present study, we provide evidence for the involvement of nuclear speckle resident proteins and RNA components in the organization of nuclear speckles. SR-family splicing factors and their binding partner, long non-coding MALAT1 RNA, can nucleate the assembly of nuclear speckles in the interphase nucleus. Depletion of SRSF1 in human cells compromises the association of splicing factors to nuclear speckles and influences the levels and activity of other SR proteins. Furthermore, on a stably integrated reporter gene locus, we demonstrate the role for SRSF1 in RNA polymerase II-mediated transcription. Our results suggest that SR proteins mediate the assembly of nuclear speckles and regulate gene expression by influencing both transcriptional and posttranscriptional activities within the cell nucleus

    Egulating gene expression through RNA nuclear retention

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    Multiple mechanisms have evolved to regulate the eukaryotic genome. We have identified CTN-RNA, a mouse tissue-specific w8 kb nuclear-retained poly(A) + RNA that regulates the level of its protein-coding partner. CTN-RNA is transcribed from the protein-coding mouse cationic amino acid transporter 2 (mCAT2) gene through alternative promoter and poly(A) site usage. CTN-RNA is diffusely distributed in nuclei and is also localized to paraspeckles. The 3�UTR of CTN-RNA contains elements for adenosine-to-inosine editing, involved in its nuclear retention. Interestingly, knockdown of CTN-RNA also downregulates mCAT2 mRNA. Under stress, CTN-RNA is posttranscriptionally cleaved to produce protein-coding mCAT2 mRNA. Our findings reveal a role of the cell nucleus in harboring RNA molecules that are not immediately needed to produce proteins but whose cytoplasmic presence is rapidly required upon physiologic stress. This mechanism of action highlights an important paradigm for the role of a nuclear-retained stable RNA transcript in regulating gene expression

    Sum rule for the backward spin polarizability of the nucleon from a backward dispersion relation

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    A new sum rule for γπ\gamma_\pi, the backward spin polarizability of the nucleon, is derived from a backward-angle dispersion relation. Taking into account single- and multi-pion photoproduction in the s-channel up to the energy 1.5 GeV and resonances in the t-channel with mass below 1.5 GeV, it is found for the proton and neutron that [γπ]p[\gamma_\pi]_p = -39.5 +/- 2.4 and [γπ]n[\gamma_\pi]_n = 52.5 +/- 2.4, respectively, in units of 10^{-4} fm^4.Comment: 10 pages, 1 figure, revtex. Submitted to Phys. Lett.

    Pleba\'nski-Demia\'nski-like solutions in metric-affine gravity

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    We consider a (non--Riemannian) metric--affine gravity theory, in particular its nonmetricity--torsion sector ``isomorphic'' to the Einstein--Maxwell theory. We map certain Einstein--Maxwell electrovacuum solutions to it, namely the Pleba\'nski--Demia\'nski class of Petrov type D metrics.Comment: 12 pages of a LaTeX-fil

    Predictive powers of chiral perturbation theory in Compton scattering off protons

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    We study low-energy nucleon Compton scattering in the framework of baryon chiral perturbation theory (Bχ\chiPT) with pion, nucleon, and Δ\Delta(1232) degrees of freedom, up to and including the next-to-next-to-leading order (NNLO). We include the effects of order p2p^2, p3p^3 and p4/Δp^4/\varDelta, with Δ300\varDelta\approx 300 MeV the Δ\Delta-resonance excitation energy. These are all "predictive" powers in the sense that no unknown low-energy constants enter until at least one order higher (i.e, p4p^4). Estimating the theoretical uncertainty on the basis of natural size for p4p^4 effects, we find that uncertainty of such a NNLO result is comparable to the uncertainty of the present experimental data for low-energy Compton scattering. We find an excellent agreement with the experimental cross section data up to at least the pion-production threshold. Nevertheless, for the proton's magnetic polarizability we obtain a value of (4.0±0.7)×104(4.0\pm 0.7)\times 10^{-4} fm3^3, in significant disagreement with the current PDG value. Unlike the previous χ\chiPT studies of Compton scattering, we perform the calculations in a manifestly Lorentz-covariant fashion, refraining from the heavy-baryon (HB) expansion. The difference between the lowest order HBχ\chiPT and Bχ\chiPT results for polarizabilities is found to be appreciable. We discuss the chiral behavior of proton polarizabilities in both HBχ\chiPT and Bχ\chiPT with the hope to confront it with lattice QCD calculations in a near future. In studying some of the polarized observables, we identify the regime where their naive low-energy expansion begins to break down, thus addressing the forthcoming precision measurements at the HIGS facility.Comment: 24 pages, 9 figures, RevTeX4, revised version published in EPJ

    An axisymmetric evolution code for the Einstein equations on hyperboloidal slices

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    We present the first stable dynamical numerical evolutions of the Einstein equations in terms of a conformally rescaled metric on hyperboloidal hypersurfaces extending to future null infinity. Axisymmetry is imposed in order to reduce the computational cost. The formulation is based on an earlier axisymmetric evolution scheme, adapted to time slices of constant mean curvature. Ideas from a previous study by Moncrief and the author are applied in order to regularize the formally singular evolution equations at future null infinity. Long-term stable and convergent evolutions of Schwarzschild spacetime are obtained, including a gravitational perturbation. The Bondi news function is evaluated at future null infinity.Comment: 21 pages, 4 figures. Minor additions, updated to agree with journal versio

    Jockeying for position: the construction of masculine identities

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    In this paper we examine the construction of masculine identities within a real-life social situation. Using data from an extensive series of interviews with small groups of sixth-form (17-18-year-old) students attending a UK-based, single-sex independent school, the analysis looks at the action orientation of different constructions of identity. More specifically, it focuses upon how the identity talk of one particular group of students were oriented towards managing their subordinate status within the school. In a number of instances the identity of the `new man' was adopted as a strategy of resistance. However, it was found that the more common strategy involved buying back into values embodied within a more traditional definition of masculinity

    Low-Energy Compton Scattering of Polarized Photons on Polarized Nucleons

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    The general structure of the cross section of γN\gamma N scattering with polarized photon and/or nucleon in initial and/or final state is systematically described and exposed through invariant amplitudes. A low-energy expansion of the cross section up to and including terms of order ω4\omega^4 is given which involves ten structure parameters of the nucleon (dipole, quadrupole, dispersion, and spin polarizabilities). Their physical meaning is discussed in detail. Using fixed-t dispersion relations, predictions for these parameters are obtained and compared with results of chiral perturbation theory. It is emphasized that Compton scattering experiments at large angles can fix the most uncertain of these structure parameters. Predictions for the cross section and double-polarization asymmetries are given and the convergence of the expansion is investigated. The feasibility of the experimental determination of some of the struture parameters is discussed.Comment: 41 pages of text, 9 figures; minor revisions prior to publication in Phys. Rev.

    Z' Decays into Four Fermions

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    If a new ZZ' is discovered with a mass 1 TeV\sim 1 \ TeV at LHC/SSC, its (rare) decays into two charged leptons plus missing transverse energy will probe the ZZ' coupling to the lepton doublet (ν,e)L(\nu,e)_L and to W+WW^+W^-, allowing further discrimination among extended electroweak models.Comment: 9 pages plus 1 figure (not included but available), UG-FT-22/9
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