15,508 research outputs found
Potential Role of Ultrafine Particles in Associations between Airborne Particle Mass and Cardiovascular Health
Numerous epidemiologic time-series studies have shown generally consistent associations of cardiovascular hospital admissions and mortality with outdoor air pollution, particularly mass concentrations of particulate matter (PM) ≤2.5 or ≤10 μm in diameter (PM(2.5), PM(10)). Panel studies with repeated measures have supported the time-series results showing associations between PM and risk of cardiac ischemia and arrhythmias, increased blood pressure, decreased heart rate variability, and increased circulating markers of inflammation and thrombosis. The causal components driving the PM associations remain to be identified. Epidemiologic data using pollutant gases and particle characteristics such as particle number concentration and elemental carbon have provided indirect evidence that products of fossil fuel combustion are important. Ultrafine particles < 0.1 μm (UFPs) dominate particle number concentrations and surface area and are therefore capable of carrying large concentrations of adsorbed or condensed toxic air pollutants. It is likely that redox-active components in UFPs from fossil fuel combustion reach cardiovascular target sites. High UFP exposures may lead to systemic inflammation through oxidative stress responses to reactive oxygen species and thereby promote the progression of atherosclerosis and precipitate acute cardiovascular responses ranging from increased blood pressure to myocardial infarction. The next steps in epidemiologic research are to identify more clearly the putative PM casual components and size fractions linked to their sources. To advance this, we discuss in a companion article (Sioutas C, Delfino RJ, Singh M. 2005. Environ Health Perspect 113:947–955) the need for and methods of UFP exposure assessment
Cooperation is related to dispersal patterns in Sino-Tibetan populations
There is growing recognition in both evolutionary biology and anthropology that dispersal is key to establishing patterns of cooperation. However, some models predict that cooperation is more likely to evolve in low dispersal (viscous) populations, while others predict that local competition for resources inhibits cooperation. Sex-biased dispersal and extra-pair mating may also have an effect. Using economic games in Sino-Tibetan populations with strikingly different dispersal patterns, we measure cooperation in 36 villages in southwestern China; we test whether social structure is associated with cooperative behaviour toward those in the neighbourhood. We find that social organization is associated with levels of cooperation in public goods and dictator games and a resource dilemma; people are less cooperative towards other villagers in communities where dispersal by both sexes is low. This supports the view that dispersal for marriage played an important role in the evolution of large-scale cooperation in human society
Baryon-Baryon Interactions
After a short survey of some topics of interest in the study of baryon-baryon
scattering, the recent Nijmegen energy dependent partial wave analysis (PWA) of
the nucleon-nucleon data is reviewed. In this PWA the energy range for both pp
and np is now 0 < Tlab < 350 MeV and a chi^2_{d.o.f.}=1.08 was reached. The
implications for the pion-nucleon coupling constants are discussed. Comments
are made with respect to recent discussions around this coupling constant in
the literature. In the second part, we briefly sketch the picture of the baryon
in several, more or less QCD-based, quark-models that have been rather
prominent in the literature. Inspired by these pictures we constructed a new
soft-core model for the nucleon-nucleon interaction and present the first
results of this model in a chi^2 -fit to the new multi-energy Nijmegen PWA.
With this new model we succeeded in narrowing the gap between theory and
experiment at low energies. For the energies Tlab = 25-320 MeV we reached a
record low chi^2_{p.d.p.} = 1.16. We finish the paper with some conclusions and
an outlook describing the extension of the new model to baryon-baryon
scattering.Comment: 12 pages LaTeX and one postscript figure included. Invited talk
presented at the XIVth European Conference of Few-Body Problems in Physics,
Amsterdam, August 23-28, 199
Recommended from our members
Stokes drift through corals
We investigate the all-penetrating drift velocities, due to surface wave
motion in an effectively inviscid fluid that overlies a saturated porous bed of
finite depth. Previous work in this area either neglects the large-scale flow
between layers [Phillips (1991)] or only considers the drift above the porous
layer [(Monismith (2007)]. We propose a model where flow is described by a
velocity potential above the porous layer, and by Darcy's law in the porous
bed, with derived matching conditions at the interface between the two layers.
The damping effect of the porous bed requires a complex wavenumber k and both a
vertical and horizontal Stokes drift of the fluid, unlike the solely horizontal
drift first derived by Stokes Stokes (1847) in a pure fluid layer. Our work
provides a physical model for coral reefs in shallow seas, where fluid drift
both above and within the reef is vitally important for maintaining a healthy
reef ecosystem [Koehl et al. (1997), Monismith (2007)]. We compare our model
with measurements by Koehl \& Hadfield (2004) and also explain the vertical
drift effects described in Koehl et al. (2007), who measured the exchange
between a coral reef layer and the (relatively shallow) sea above
Electroweak Symmetry Breaking in the DSSM
We study the theoretical and phenomenological consequences of modifying the
Kahler potential of the MSSM two Higgs doublet sector. Such modifications
naturally arise when the Higgs sector mixes with a quasi-hidden conformal
sector, as in some F-theory GUT models. In the Delta-deformed Supersymmetric
Standard Model (DSSM), the Higgs fields are operators with non-trivial scaling
dimension 1 < Delta < 2. The Kahler metric is singular at the origin of field
space due to the presence of quasi-hidden sector states which get their mass
from the Higgs vevs. The presence of these extra states leads to the fact that
even as Delta approaches 1, the DSSM does not reduce to the MSSM. In
particular, the Higgs can naturally be heavier than the W- and Z-bosons.
Perturbative gauge coupling unification, a large top quark Yukawa, and
consistency with precision electroweak can all be maintained for Delta close to
unity. Moreover, such values of Delta can naturally be obtained in
string-motivated constructions. The quasi-hidden sector generically contains
states charged under SU(5)_GUT as well as gauge singlets, leading to a rich,
albeit model-dependent, collider phenomenology.Comment: v3: 40 pages, 3 figures, references added, typos correcte
Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication.
published_or_final_versio
Recommended from our members
A demonstration of 'broken' visual space
It has long been assumed that there is a distorted mapping between real and ‘perceived’ space, based on demonstrations of systematic errors in judgements of slant, curvature, direction and separation. Here, we have applied a direct test to the notion of a coherent visual space. In an immersive virtual environment, participants judged the relative distance of two squares displayed in separate intervals. On some trials, the virtual scene expanded by a factor of four between intervals although, in line with recent results, participants did not report any noticeable change in the scene. We found that there was no consistent depth ordering of objects that can explain the distance matches participants made in this environment (e.g. A > B > D yet also A < C < D) and hence no single one-to-one mapping between participants’ perceived space and any real 3D environment. Instead, factors that affect pairwise comparisons of distances dictate participants’ performance. These data contradict, more directly than previous experiments, the idea that the visual system builds and uses a coherent 3D internal representation of a scene
Femtosecond laser surface structuring of silicon with Gaussian and optical vortex beams
We report an experimental analysis of femtosecond laser induced surface structuring of silicon by exploiting both Gaussian and Optical Vortex beams. In particular, we show how different surface patterns, consisting of quasi-periodic ripples and grooves, can be obtained by using different states of polarization offered by optical vortex beams. Both for Gaussian and optical vortex beams, an increase of the number of laser pulses, N, or beam energy, E-0, leads to a progressive predominance of the grooves coverage, with ripples confined in specific regions of the irradiated area at lower fluence. The average period of ripples and grooves shows a different dependence as a function of both E-0 and N, underlying important differences in mechanisms leading to the formation of ripples and grooves. In particular, our experimental characterization allows identifying a preliminary stage of grooves generation with rudimental surface structures, preferentially directed parallel to the laser polarization. This supports the idea that one possible mechanism of grooves formation lies in the progressive aggregation of clusters of nanopartides densely decorating the ripples. Our experimental findings provide important indications on the basic understanding of the processes involved in laser surface structuring with ultrashort pulses that can guide the design of the surface patterns. (C) 2016 Elsevier B.V. All rights reserved
- …