Long-term radial-velocity variations of the Sun as a star: The HARPS view

Stellar radial velocities play a fundamental role in the discovery of extrasolar planets and the measurement of their physical parameters as well as in the study of stellar physical properties. We investigate the impact of the solar activity on the radial velocity of the Sun using the HARPS spectrograph to obtain measurements that can be directly compared with those acquired in the extrasolar planet search programs. We use the Moon, the Galilean satellites, and several asteroids as reflectors to measure the radial velocity of the Sun as a star and correlate it with disc-integrated chromospheric and magnetic indexes of solar activity that are similar to stellar activity indexes. We discuss in detail the systematic effects that affect our measurements and the methods to account for them. We find that the radial velocity of the Sun as a star is positively correlated with the level of its chromospheric activity at about 95 percent significance level. The amplitude of the long-term variation measured in the 2006-2014 period is 4.98 \pm 1.44 m/s, in good agreement with model predictions. The standard deviation of the residuals obtained by subtracting a linear best fit is 2.82 m/s and is due to the rotation of the reflecting bodies and the intrinsic variability of the Sun on timescales shorter than the activity cycle. A correlation with a lower significance is detected between the radial velocity and the mean absolute value of the line-of-sight photospheric magnetic field flux density. Our results confirm similar correlations found in other late-type main-sequence stars and provide support to the predictions of radial velocity variations induced by stellar activity based on current models.Comment: 11 pages, 7 figures, 2 tables, 1 Appendix; accepted by Astronomy and Astrophysic

Survey Validation: Perception and Knowledge of Concussions Amongst NCAA Student-Athletes

Background: Sport related concussion diagnosis can often be challenging as all athletes experience different signs and symptoms and may not have the correct knowledge to be able to identify every possible symptom of a concussion. When a concussion is sustained by an athlete, it is crucial that the injury is handled correctly not only by medical providers, but more importantly by the athlete themselves. Because the most common symptoms being a headache, dizziness, etc., a clinical diagnosis is highly dependent on the patient self-reporting their own symptoms. It is important for an athlete to be able to recognize a concussion symptom, know the risks of sustaining a concussion and having the appropriate knowledge to be able to report a concussion. This study aims to validate a survey that can be used to test NCAA athlete’s knowledge and perception of concussions. Methods: Twenty-eight questions were prepared following evidence-based research. Questions were removed and adjusted based on experts review Expert responses were analyzed using I-CVI, S-CVI/Ave, S-CVI/UA to determine content validity and a modified kappa was used to determine the probability of chance amongst expert’s answers. Results: Eleven experts were used to score the survey along with 66 student-athletes to complete the survey once it was adjusted based on expert review. One question was removed from the survey entirely and another question was modified. A finalized survey of 27 questions was chosen. The I-CVIs ranged from 0.636 to 1.00, the S-CVI/Ave = 0.93, and the S-CVI/UA = 0.50 was taken as acceptable amongst the 11 experts. Conclusion: We conclude that this questionnaire has met the content validity criteria. However, when items were separated into two groups, knowledge and perception, Cronbach’s alpha deemed both groups had poor inter-relatedness between items

A rotor-mounted digital instrumentation system for helicopter blade flight research measurements

A rotor mounted flight instrumentation system developed for helicopter rotor blade research is described. The system utilizes high speed digital techniques to acquire research data from miniature pressure transducers on advanced rotor airfoils which are flight tested on an AH-1G helicopter. The system employs microelectronic pulse code modulation (PCM) multiplexer digitizer stations located remotely on the blade and in a hub mounted metal canister. As many as 25 sensors can be remotely digitized by a 2.5 mm thick electronics package mounted on the blade near the tip to reduce blade wiring. The electronics contained in the canister digitizes up to 16 sensors, formats these data with serial PCM data from the remote stations, and transmits the data from the canister which is above the plane of the rotor. Data are transmitted over an RF link to the ground for real time monitoring and to the helicopter fuselage for tape recording. The complete system is powered by batteries located in the canister and requires no slip rings on the rotor shaft

The Galactic disk mass-budget : II. Brown dwarf mass-function and density

In this paper, we extend the calculations conducted previously in the stellar regime to determine the brown dwarf IMF in the Galactic disk. We perform Monte Carlo calculations taking into account the brown dwarf formation rate, spatial distribution and binary fraction. Comparison with existing surveys seems to exclude a power-law MF as steep as the one determined in the stellar regime below 1 \msol and tends to favor a more flatish behaviour. Comparison with methane-dwarf detections tends to favor an eventually decreasing form like the lognormal or the more general exponential distributions determined in the previous paper. We calculate predicting brown dwarf counts in near-infrared color diagrams and brown dwarf discovery functions. These calculations yield the presently most accurate determination of the brown dwarf census in the Galactic disk. The brown dwarf number density is comparable to the stellar one, $n_{BD}\simeq n_\star\simeq 0.1$ pc$^{-3}$. The corresponding brown dwarf mass density, however, represents only about 10% of the stellar contribution, i.e. \rho_{BD}\simle 5.0\times 10^{-3} \mvol. Adding up the local stellar density determined previously yields the density of star-like objects, stars and brown dwarfs, in the solar neighborhood \rho_\odot \approx 5.0\times 10^{-2} \mvol.Comment: 39 pages, Latex file, uses aasms4.sty, to be published in ApJ, corrected version with correct figure

Establishing the values for patient engagement (PE) in health-related quality of life (HRQoL) research: an international, multiple-stakeholder perspective

PurposeActive patient engagement is increasingly viewed as essential to ensuring that patient-driven perspectives are considered throughout the research process. However, guidance for patient engagement (PE) in HRQoL research does not exist, the evidence-base for practice is limited, and we know relatively little about underpinning values that can impact on PE practice. This is the first study to explore the values that should underpin PE in contemporary HRQoL research to help inform future good practice guidance. MethodsA modified ‘World Café’ was hosted as a collaborative activity between patient partners, clinicians and researchers: self-nominated conference delegates participated in group discussions to explore values associated with the conduct and consequences of PE. Values were captured via post-it notes and by nominated note-takers. Data were thematically analysed: emergent themes were coded and agreement checked. Association between emergent themes, values and the Public Involvement Impact Assessment Framework were explored. ResultsEighty participants, including 12 patient partners, participated in the 90-min event. Three core values were defined: (1) building relationships; (2) improving research quality and impact; and (3) developing best practice. Participants valued the importance of building genuine, collaborative and deliberative relationships—underpinned by honesty, respect, co-learning and equity—and the impact of effective PE on research quality and relevance. Conclusions An explicit statement of values seeks to align all stakeholders on the purpose, practice and credibility of PE activities. An innovative, flexible and transparent research environment was valued as essential to developing a trustworthy evidence-base with which to underpin future guidance for good PE practice.Peer reviewe

Use and outcomes of targeted therapies in early and metastatic HER2-positive breast cancer in Australia: Protocol detailing observations in a whole of population cohort

Background: The management of human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) has changed dramatically with the introduction and widespread use of HER2-targeted therapies. However, there is relatively limited real-world information on patterns of use, effectiveness and safety in whole of population cohorts. The research programme detailed in this protocol will generate evidence on the prescribing patterns, safety monitoring and outcomes of patients with BC treated with HER2- targeted therapies in Australia. Methods/design: Our ongoing research programme will involve a series of retrospective cohort studies that include every patient accessing Commonwealth-funded HER2-targeted therapies for the treatment of early BC and advanced BC in Australia. At the time of writing, our cohorts consist of 11 406 patients with early BC and 5631 with advanced BC who accessed trastuzumab and lapatinib between 2001 and 2014. Pertuzumab and trastuzumab emtansine were publicly funded for metastatic BC in 2015, and future data updates will include patients accessing these medicines. We will use dispensing claims for cancer and other medicines, medical service claims and demographics data for each patient accessing HER2- targeted therapies to undertake this research. Ethics and dissemination: Ethics approval has been granted by the Population Health Service Research Ethics Committee and data access approval has been granted by the Australian Department of Human Services (DHS) External Review Evaluation Committee. Our findings will be reported in peer-reviewed publications, conference presentations and policy forums. By providing detailed information on the use and outcomes associated with HER2-targeted therapies in a national cohort treated in routine clinical care, our research programme will better inform clinicians and patients about the real-world use of these treatments and will assist third-party payers to better understand the use and economic costs of these treatments

Space Velocities of L- and T-type Dwarfs

(Abridged) We have obtained radial velocities of a sample of 18 ultracool dwarfs (M6.5-T8) using high-resolution, near-infrared spectra obtained with NIRSPEC and the Keck II telescope. We have confirmed that the radial velocity of Gl 570 D is coincident with that of the K-type primary star Gl 570 A, thus providing additional support for their true companionship. The presence of planetary-mass companions around 2MASS J05591914-1404488 (T4.5V) has been analyzed using five NIRSPEC radial velocity measurements obtained over a period of 4.37 yr. We have computed UVW space motions for a total of 21 L and T dwarfs within 20 pc of the Sun. This population shows UVW velocities that nicely overlap the typical kinematics of solar to M-type stars within the same spatial volume. However, the mean Galactic (44.2 km/s) and tangential (36.5 km/s) velocities of the L and T dwarfs appear to be smaller than those of G to M stars. A significant fraction (~40%) of the L and T dwarfs lies near the Hyades moving group (0.4-2 Gyr), which contrasts with the 10-12% found for earlier-type stellar neighbors. Additionally, the distributions of all three UVW components (sigma_{UVW} = 30.2, 16.5, 15.8 km/s) and the distributions of the total Galactic (sigma_{v_tot} = 19.1 km/s) and tangential (sigma_{v_t} = 17.6 km/s) velocities derived for the L and T dwarf sample are narrower than those measured for nearby G, K, and M-type stars, but similar to the dispersions obtained for F stars. This suggests that, in the solar neighborhood, the L- and T-type ultracool dwarfs in our sample (including brown dwarfs) is kinematically younger than solar-type to early M stars with likely ages in the interval 0.5-4 Gyr.Comment: Accepted for publication in Ap

Using PROMs in healthcare. Who should be in the driving seat - policy makers, health professionals, methodologists or patients?

Editorial - No abstrac