Relations between Directional Spectral Vegetation Indices and Leaf Area and Absorbed Radiation in Alfalfa

s ensors on satellite platforms with extreme view angles have been increasingly used to analyze regional and global vegetation cover and productivity because of frequent observations. This study, using experimental and theoretical methods, analyzed variations in vegetation indices with sun-view geometry as a means of understanding the sensitivity of relations beween vegetation indices and the biophysical properties, the leaf area index (LAI), and the instantaneous fraction of absorbed photosynthetically active radiation (fAPAR). Canopy bidirectional reflectance factors (BRFs) of an alfalfa crop were measured and simulated at a variety of solar and view zenith angles. Also, fAPAR, LAI, and leaf optical properties were measured. Measured and simulated canopy re$ectances agreed generally within 1% (absolute). Normalized dijj5erence and simple ratio vegetation indices (NDVI and SRVI, respectively), derived from BRFs, varied with view and solar zenith angles. The minimum for near-infrared (NIR) BRFs and relatively high red BRFs generally occurred near nadir, resulting in some of the lowest vegetation index values. Highest VI value-s were generally obtained at forward view angles. Variation of NDVI with sun-view-geometry was greatest at LAls ~2, whereas the range in SRVI was greatest for LAls\u3e2. Measured reflectances indicate that relations between NDVl and LA1 and between SRVl and fAPAR were curvilinear across all solar and view zenith angle combinations in the solar principal plane, whereas relations between SRVI and LA1 and between NDVI and fAPAR varied from linear to curvilinear. Analyses revealed that vegetation, indices at large view zenith angles were poorly correlated with fAPAR, whereas those at small zenith angles were strongly correlated. In general, vegetation indices were more sensitive to fAPAR than to LAI, which is attributed to the fact that fAPAR is a radiation quantity, whereas LAI is nonlinearly related to radiation. Regression of fAPAR with VI values derived from combinations of red and NlR BRFs from similar and nonsimilar directions indicates that the highest correlation is in near-nadir and backscatter directions. However, further investigation into variations of relations between remotely sensed observations and canopy attributes and into the usefulness of of-nadir in extracting information is recommended. OElsevier Science Inc., 199

Pterodactyl: Trade Study for an Integrated Control System Design of a Mechanically Deployable Entry Vehicle

This paper presents the trade study method used to evaluate and downselect from a set of guidance and control (G&C) system designs for a mechanically Deployable Entry Vehicle (DEV). The Pterodactyl project was prompted by the challenge to develop an effective G&C system for a vehicle without a backshell, which is the case for DEVs. For the DEV, the project assumed a specific aeroshell geometry pertaining to an Adaptable, Deployable Entry and Placement Technology (ADEPT) vehicle, which was successfully developed by NASAs Space Technology Mission Directorate (STMD) prior to this study. The Pterodactyl project designed three different entry G&C systems for precision targeting. This paper details the Figures of Merit (FOMs) and metrics used during the course of the projects G&C system assessment. The relative importance of the FOMs was determined from the Analytic Hierarchy Process (AHP), which was used to develop weights that were combined with quantitative design metrics and engineering judgement to rank the G&C systems against one another. This systematic method takes into consideration the projects input while simultaneously reducing unintentional judgement bias and ultimately was used to select a single G&C design for the project to pursue in the next design phase

Sibling Aggression, Feeding Rates, and Hatch Rank of Nestling Red-Shouldered Hawks (Buteo lineatus)

Article describes how, in many raptor species, hatching asynchrony results in a size hierarchy among nestlings, which may facilitate brood reduction by means of sibling aggression-induced mortality, especially in times of low food resources. The authors studied the influence of hatch rank, brood size, and brood age on aggression and feeding rates among Red-shouldered Hawk (Buteo lineatus) nestlings in suburban southwestern Ohio

A One Health overview, facilitating advances in comparative medicine and translational research.

Table of contentsA1 One health advances and successes in comparative medicine and translational researchCheryl StroudA2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaIgor Dmitriev, Elena Kashentseva, Jeffrey N. Bryan, David T. CurielA3 Viroimmunotherapy for malignant melanoma in the companion dog modelJeffrey N. Bryan, David Curiel, Igor Dmitriev, Elena Kashentseva, Hans Rindt, Carol Reinero, Carolyn J. HenryA4 Of mice and men (and dogs!): development of a commercially licensed xenogeneic DNA vaccine for companion animals with malignant melanomaPhilip J. BergmanA5 Successful immunotherapy with a recombinant HER2-expressing Listeria monocytogenes in dogs with spontaneous osteosarcoma paves the way for advances in pediatric osteosarcomaNicola J. Mason, Josephine S. Gnanandarajah, Julie B. Engiles, Falon Gray, Danielle Laughlin, Anita Gaurnier-Hausser, Anu Wallecha, Margie Huebner, Yvonne PatersonA6 Human clinical development of ADXS-HER2Daniel O'ConnorA7 Leveraging use of data for both human and veterinary benefitLaura S. TremlA8 Biologic replacement of the knee: innovations and early clinical resultsJames P. StannardA9 Mizzou BioJoint Center: a translational success storyJames L. CookA10 University and industry translational partnership: from the lab to commercializationMarc JacobsA11 Beyond docking: an evolutionarily guided OneHealth approach to drug discoveryGerald J. Wyckoff, Lee Likins, Ubadah Sabbagh, Andrew SkaffA12 Challenges and opportunities for data applications in animal health: from precision medicine to precision husbandryAmado S. GuloyA13 A cloud-based programmable platform for healthHarlen D. HaysA14 Comparative oncology: One Health in actionAmy K. LeBlancA15 Companion animal diseases bridge the translational gap for human neurodegenerative diseaseJoan R. Coates, Martin L. Katz, Leslie A. Lyons, Gayle C. Johnson, Gary S. Johnson, Dennis P. O'BrienA16 Duchenne muscular dystrophy gene therapyDongsheng DuanA17 Polycystic kidney disease: cellular mechanisms to emerging therapiesJames P. CalvetA18 The domestic cat as a large animal model for polycystic kidney diseaseLeslie A. Lyons, Barbara GandolfiA19 The support of basic and clinical research by the Polycystic Kidney Disease FoundationDavid A. BaronA20 Using naturally occurring large animal models of human disease to enable clinical translation: treatment of arthritis using autologous stromal vascular fraction in dogsMark L. WeissA21 Regulatory requirements regarding clinical use of human cells, tissues, and tissue-based productsDebra A. WebsterA22 Regenerative medicine approaches to Type 1 diabetes treatmentFrancis N. KaranuA23 The zoobiquity of canine diabetes mellitus, man's best friend is a friend indeed-islet transplantationEdward J. RobbA24 One Medicine: a development model for cellular therapy of diabetesRobert J. Harman

Pterodactyl: Trade Study for an Integrated Control System Design of a Mechanically Deployed Entry Vehicle

This paper presents a trade study method used to evaluate and down-select from a set of guidance and control (G&C) system designs for a mechanically deployable entry vehicle (DEV). The Pterodactyl project, funded by NASA's Space Technology Mission Directorate (STMD), was prompted by the challenge to develop an effective G&C system for a vehicle without a backshell, which is the case for DEVs. For the DEV, the project assumed a specific aeroshell geometry pertaining to an Adaptable, Deployable, Entry Placement Technology (ADEPT) vehicle, which was successfully developed by STMD prior to this study. The Pterodactyl project designed three different G&C systems for the vehicle's precise entry, which this paper briefly discusses. This paper details the Figures of Merit (FOMs) and metrics used during the course of the project's G&C system assessment. Each G&C configuration was traded against the three FOMs categories: G&C system performance, affordability and life cycle costs, and safety and mission success. The relative importance of the FOMs was determined from the Analytical Hierarchy Process (AHP), which was used to develop weights that were combined with quantitative design metrics and engineering judgement to rank the G&C systems against one another. This systematic method takes into consideration the project's input while simultaneously reducing unintentional judgement bias and ultimately was used to select a single G&C design for the project to continue pursuing in the next prototyping and testing phase

Search for direct third-generation squark pair production in final states with missing transverse momentum and two b-jets in s√=8s=8 TeV pp collisions with the ATLAS detector

The results of a search for pair production of supersymmetric partners of the Standard Model third-generation quarks are reported. This search uses 20.1 fb^−1 of pp collisions at s√=8s=8 TeV collected by the ATLAS experiment at the Large Hadron Collider. The lightest bottom and top squarks ( b˜1 and t˜1 respectively) are searched for in a final state with large missing transverse momentum and two jets identified as originating from b-quarks. No excess of events above the expected level of Standard Model background is found. The results are used to set upper limits on the visible cross section for processes beyond the Standard Model. Exclusion limits at the 95 % confidence level on the masses of the third-generation squarks are derived in phenomenological supersymmetric R-parity-conserving models in which either the bottom or the top squark is the lightest squark. The b˜1 is assumed to decay via b˜1 → bχ~01 and the t˜1 via t˜1 → bχ~±1, with undetectable products of the subsequent decay of the χ∼±1 due to the small mass splitting between the χ∼±1 and the χ∼01

Spectrum of Infection and Risk Factors for Human Monkeypox, United States, 2003

Infection is associated with proximity to virus-infected animals and their excretions and secretions

High-Fidelity, Frequency-Flexible Two-Qubit Fluxonium Gates with a Transmon Coupler

We propose and demonstrate an architecture for fluxonium-fluxonium two-qubit gates mediated by transmon couplers (FTF, for fluxonium-transmon-fluxonium). Relative to architectures that exclusively rely on a direct coupling between fluxonium qubits, FTF enables stronger couplings for gates using non-computational states while simultaneously suppressing the static controlled-phase entangling rate ($ZZ$) down to kHz levels, all without requiring strict parameter matching. Here we implement FTF with a flux-tunable transmon coupler and demonstrate a microwave-activated controlled-Z (CZ) gate whose operation frequency can be tuned over a 2 GHz range, adding frequency allocation freedom for FTF's in larger systems. Across this range, state-of-the-art CZ gate fidelities were observed over many bias points and reproduced across the two devices characterized in this work. After optimizing both the operation frequency and the gate duration, we achieved peak CZ fidelities in the 99.85-99.9\% range. Finally, we implemented model-free reinforcement learning of the pulse parameters to boost the mean gate fidelity up to $99.922\pm0.009\%$, averaged over roughly an hour between scheduled training runs. Beyond the microwave-activated CZ gate we present here, FTF can be applied to a variety of other fluxonium gate schemes to improve gate fidelities and passively reduce unwanted $ZZ$ interactions.Comment: 23 pages, 16 figure

Evolution of 1/f1/f Flux Noise in Superconducting Qubits with Weak Magnetic Fields

The microscopic origin of $1/f$ magnetic flux noise in superconducting circuits has remained an open question for several decades despite extensive experimental and theoretical investigation. Recent progress in superconducting devices for quantum information has highlighted the need to mitigate sources of qubit decoherence, driving a renewed interest in understanding the underlying noise mechanism(s). Though a consensus has emerged attributing flux noise to surface spins, their identity and interaction mechanisms remain unclear, prompting further study. Here we apply weak in-plane magnetic fields to a capacitively-shunted flux qubit (where the Zeeman splitting of surface spins lies below the device temperature) and study the flux-noise-limited qubit dephasing, revealing previously unexplored trends that may shed light on the dynamics behind the emergent $1/f$ noise. Notably, we observe an enhancement (suppression) of the spin-echo (Ramsey) pure dephasing time in fields up to $B=100~\text{G}$. With direct noise spectroscopy, we further observe a transition from a $1/f$ to approximately Lorentzian frequency dependence below 10 Hz and a reduction of the noise above 1 MHz with increasing magnetic field. We suggest that these trends are qualitatively consistent with an increase of spin cluster sizes with magnetic field. These results should help to inform a complete microscopic theory of $1/f$ flux noise in superconducting circuits

CD94+ Natural Killer cells potentiate pulmonary ischemia-reperfusion injury

Pulmonary ischemia-reperfusion injury (IRI) is a major contributor to poor lung transplant outcomes. We recently demonstrated a central role of airway-centered NK cells in mediating IRI; however, there are no existing effective therapies for directly targeting NK cells in humans. We hypothesized that a depleting anti-CD94 monoclonal antibody (mAb) would provide therapeutic benefit in mouse and human models of IRI based on high levels of KLRD1 (CD94) transcripts in bronchoalveolar lavage samples from lung transplant patients. We found that CD94 is highly expressed on mouse and human NK cells, with increased expression during IRI. Anti-mouse and anti-human mAbs against CD94 showed effective NK cell depletion in mouse and human models and blunted lung damage and airway epithelial killing. In two different allogeneic orthotopic lung transplant mouse models, anti-CD94 treatment during induction reduced early lung injury and chronic inflammation relative to control therapies. Anti-CD94 did not increase donor antigen-presenting cells that could alter long-term graft acceptance. Lung transplant induction regimens incorporating anti-CD94 treatment may safely improve early clinical outcomes