Experimental determination of the state-dependent enhancement of the electron-positron momentum density in solids

The state-dependence of the enhancement of the electron-positron momentum density is investigated for some transition and simple metals (Cr, V, Ag and Al). Quantitative comparison with linearized muffin-tin orbital calculations of the corresponding quantity in the first Brillouin zone is shown to yield a measurement of the enhancement of the s, p and d states, independent of any parameterizations in terms of the electron density local to the positron. An empirical correction that can be applied to a first-principles state-dependent model is proposed that reproduces the measured state-dependence very well, yielding a general, predictive model for the enhancement of the momentum distribution of positron annihilation measurements, including those of angular correlation and coincidence Doppler broadening techniques

Rotational Widths for Use in the Tully-Fisher Relation. II. The Impact of Surface Brightness

Using a large sample of spiral galaxies for which 21 cm single-dish and/or long-slit optical spectra are available, we make a detailed comparison between various estimates of rotational widths. Different optical width estimators are considered and their limitations discussed, with emphasis on biases associated with rotation curve properties (shape and extent) and disk central surface brightness. The best match with HI rotational velocities is obtained with Polyex widths, which are measured at the optical radius (encompassing a fixed fraction of the total light of the galaxy) from a model fit to the rotation curve. In contrast with Polyex widths, optical rotational velocities measured at 2.15 disk scale lengths r_d deviate from HI widths by an amount that correlates with the central surface brightness of the disk. This bias occurs because the rotation curves of galaxies are in general still rising at 2.15 r_d, and the fraction of total mass contained within this radius decreases with increasing disk surface brightness. Statistical corrections, parameterized by the radial extent of the observed rotation curve, are provided to reduce Polyex and HI width measurements into a homogeneous system. This yields a single robust estimate of rotational velocity to be used for applications of disk scaling relations.Comment: 13 pages, 8 figures. To appear in the Astronomical Journal (August 2007

The electronic structure of {\em R}NiC2_2 intermetallic compounds

First-principles calculations of the electronic structure of members of the $R$NiC$_2$ series are presented, and their Fermi surfaces investigated for nesting propensities which might be linked to the charge-density waves exhibited by certain members of the series ($R$ = Sm, Gd and Nd). Calculations of the generalized susceptibility, $\chi_{0}({\bf q},\omega)$, show strong peaks at the same ${\bf q}$-vector in both the real and imaginary parts for these compounds. Moreover, this peak occurs at a wavevector which is very close to that experimentally observed in SmNiC$_2$. In contrast, for LaNiC$_2$ (which is a superconductor below 2.7K) as well as for ferromagnetic SmNiC$_2$, there is no such sharp peak. This could explain the absence of a charge-density wave transition in the former, and the destruction of the charge-density wave that has been observed to accompany the onset of ferromagnetic order in the latter.Comment: 5 pages, 7 figures. Accepted for publication in Phys. Rev.

Multiple prebiotic metals mediate translation.

Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a functional ancestral state. First, SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension) was used to compare the effect of Mg2+, Fe2+, and Mn2+ on the tertiary structure of rRNA. Then, we used in vitro translation reactions to test whether Fe2+ or Mn2+ could mediate protein production, and quantified ribosomal metal content. We found that (i) Mg2+, Fe2+, and Mn2+ had strikingly similar effects on rRNA folding; (ii) Fe2+ and Mn2+ can replace Mg2+ as the dominant divalent cation during translation of mRNA to functional protein; and (iii) Fe and Mn associate extensively with the ribosome. Given that the translation system originated and matured when Fe2+ and Mn2+ were abundant, these findings suggest that Fe2+ and Mn2+ played a role in early ribosomal evolution

Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy

This is the author accepted manuscript. The final version is available from Taylor & Francis via the DOI in this record.This work was supported in part by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/

Development of large radii half-wave plates for CMB satellite missions

The successful European Space Agency (ESA) Planck mission has mapped the Cosmic Microwave Background (CMB) temperature anisotropy with unprecedented accuracy. However, Planck was not designed to detect the polarised components of the CMB with comparable precision. The BICEP2 collaboration has recently reported the first detection of the B-mode polarisation. ESA is funding the development of critical enabling technologies associated with B-mode polarisation detection, one of these being large diameter half-wave plates. We compare different polarisation modulators and discuss their respective trade-offs in terms of manufacturing, RF performance and thermo-mechanical properties. We then select the most appropriate solution for future satellite missions, optimized for the detection of B-modes.Comment: 16 page

Brain tissue properties differentiate between motor and limbic basal ganglia circuits

Despite advances in understanding basic organizational principles of the human basal ganglia, accurate in vivo assessment of their anatomical properties is essential to improve early diagnosis in disorders with corticosubcortical pathology and optimize target planning in deep brain stimulation. Main goal of this study was the detailed topological characterization of limbic, associative, and motor subdivisions of the subthalamic nucleus (STN) in relation to corresponding corticosubcortical circuits. To this aim, we used magnetic resonance imaging and investigated independently anatomical connectivity via white matter tracts next to brain tissue properties. On the basis of probabilistic diffusion tractography we identified STN subregions with predominantly motor, associative, and limbic connectivity. We then computed for each of the nonoverlapping STN subregions the covariance between local brain tissue properties and the rest of the brain using high-resolution maps of magnetization transfer (MT) saturation and longitudinal (R1) and transverse relaxation rate (R2*). The demonstrated spatial distribution pattern of covariance between brain tissue properties linked to myelin (R1 and MT) and iron (R2*) content clearly segregates between motor and limbic basal ganglia circuits. We interpret the demonstrated covariance pattern as evidence for shared tissue properties within a functional circuit, which is closely linked to its function. Our findings open new possibilities for investigation of changes in the established covariance pattern aiming at accurate diagnosis of basal ganglia disorders and prediction of treatment outcom

A Digital Archive of HI 21 cm Line Spectra of Optically-targeted Galaxies

We present a homogeneous compilation of HI spectral parameters extracted from global 21 cm line spectra for some 9000 galaxies in the local universe (heliocentric velocity -200 < V_Sun < 28,000 km/s) obtained with a variety of large single dish radio telescopes but reanalyzed using a single set of parameter extraction algorithms. Corrections to the observed HI line flux for source extent and pointing offsets and to the HI line widths for instrumental broadening and smoothing are applied according to model estimates to produce a homogenous catalog of derived properties with quantitative error estimates. Where the redshift is available from optical studies, we also provide flux measurements for an additional 156 galaxies classified as marginal HI detections and rms noise limits for 494 galaxies classified as nondetections. Given the diverse nature of the observing programs contributing to it, the characteristics of the combined dataset are heterogeneous, and as such, the compilation is neither integrated HI line flux nor peak flux limited. However, because of the large statistical base and homogenous reprocessing, the spectra and spectral parameters of galaxies in this optically targeted sample can be used to complement data obtained at other wavelengths to characterize the properties of galaxies in the local universe and to explore the large scale structures in which they reside.Comment: 13 pages, 9 figures, 3 external online tables, accepted for publication in ApJ