Die euroskeptische Politik der tschechischen Parteien

Nach dem Fall des alten Regimes herrscht im ganzen Mittel- und Osteuropa eine positive Einstellung gegenüber der Europäischen Union. Unter der Elite und der Bevölkerung besteht einen Konsens über die Eingliederung des eigenen Staates in die Europäische Union unter dem Motto „Rückkehr nach Europa“. Die europäischen Themen werden in der national-politischen Debatte immer wichtiger und die Euphorie, man könnte sogar die Naivität sagen, des Anfangs der 1990er wird am Ende dieses Jahrzehnt durch eine Ernüchterung, durch eine Skepsis ausgetauscht. Mit dem sich nähernden Beitritt zur Europäischen Union und mit der Verstärkung des Prozesses der Beitrittsverhandlungen kristallisieren sich zunehmende euroskeptische Strömungen in der Tschechischen Republik heraus. Aufgrund der bestehenden Literatur wird in der ersten Phase dieser Studie der Begriff Euroskeptizismus konzeptualisiert. Am Fallbeispiel der Tschechischen Republik werden dann relevante politische Parteien, vor allem die Demokratische Bürgerpartei, im Kontext des Euroskeptizismus abgebildet. Im Weiteren werden auch die Einstellungen zum Prozess der europäischen Integration in der Bevölkerung dargestellt und es wird untersucht, ob es Beziehungen zwischen den WählerInnen und den politischen Parteien in Bezug auf die Europäische Union gibt

Impact of Non-Robotic Assisted Therapy for Improvement of Mobility of Paretic Upper Extremity Caused by Cerebral Palsy Compared to Classical Kinesiotherapy

Background: The aim of the clinical study was to investigate and compare the impact of non-robotic assisted therapy to classical kinesiotherapy to improve the function abilities of upper extremity

Microarray analysis and scale-free gene networks identify candidate regulators in drought-stressed roots of loblolly pine (P. taeda L.)

<p>Abstract</p> <p>Background</p> <p>Global transcriptional analysis of loblolly pine (<it>Pinus taeda </it>L.) is challenging due to limited molecular tools. PtGen2, a 26,496 feature cDNA microarray, was fabricated and used to assess drought-induced gene expression in loblolly pine propagule roots. Statistical analysis of differential expression and weighted gene correlation network analysis were used to identify drought-responsive genes and further characterize the molecular basis of drought tolerance in loblolly pine.</p> <p>Results</p> <p>Microarrays were used to interrogate root cDNA populations obtained from 12 genotype × treatment combinations (four genotypes, three watering regimes). Comparison of drought-stressed roots with roots from the control treatment identified 2445 genes displaying at least a 1.5-fold expression difference (false discovery rate = 0.01). Genes commonly associated with drought response in pine and other plant species, as well as a number of abiotic and biotic stress-related genes, were up-regulated in drought-stressed roots. Only 76 genes were identified as differentially expressed in drought-recovered roots, indicating that the transcript population can return to the pre-drought state within 48 hours. Gene correlation analysis predicts a scale-free network topology and identifies eleven co-expression modules that ranged in size from 34 to 938 members. Network topological parameters identified a number of central nodes (hubs) including those with significant homology (E-values ≤ 2 × 10^-30) to 9-cis-epoxycarotenoid dioxygenase, zeatin O-glucosyltransferase, and ABA-responsive protein. Identified hubs also include genes that have been associated previously with osmotic stress, phytohormones, enzymes that detoxify reactive oxygen species, and several genes of unknown function.</p> <p>Conclusion</p> <p>PtGen2 was used to evaluate transcriptome responses in loblolly pine and was leveraged to identify 2445 differentially expressed genes responding to severe drought stress in roots. Many of the genes identified are known to be up-regulated in response to osmotic stress in pine and other plant species and encode proteins involved in both signal transduction and stress tolerance. Gene expression levels returned to control values within a 48-hour recovery period in all but 76 transcripts. Correlation network analysis indicates a scale-free network topology for the pine root transcriptome and identifies central nodes that may serve as drivers of drought-responsive transcriptome dynamics in the roots of loblolly pine.</p

Functional annotation of the transcriptome of Sorghum bicolor in response to osmotic stress and abscisic acid

<p>Abstract</p> <p>Background</p> <p>Higher plants exhibit remarkable phenotypic plasticity allowing them to adapt to an extensive range of environmental conditions. Sorghum is a cereal crop that exhibits exceptional tolerance to adverse conditions, in particular, water-limiting environments. This study utilized next generation sequencing (NGS) technology to examine the transcriptome of sorghum plants challenged with osmotic stress and exogenous abscisic acid (ABA) in order to elucidate genes and gene networks that contribute to sorghum's tolerance to water-limiting environments with a long-term aim of developing strategies to improve plant productivity under drought.</p> <p>Results</p> <p>RNA-Seq results revealed transcriptional activity of 28,335 unique genes from sorghum root and shoot tissues subjected to polyethylene glycol (PEG)-induced osmotic stress or exogenous ABA. Differential gene expression analyses in response to osmotic stress and ABA revealed a strong interplay among various metabolic pathways including abscisic acid and 13-lipoxygenase, salicylic acid, jasmonic acid, and plant defense pathways. Transcription factor analysis indicated that groups of genes may be co-regulated by similar regulatory sequences to which the expressed transcription factors bind. We successfully exploited the data presented here in conjunction with published transcriptome analyses for rice, maize, and Arabidopsis to discover more than 50 differentially expressed, drought-responsive gene orthologs for which no function had been previously ascribed.</p> <p>Conclusions</p> <p>The present study provides an initial assemblage of sorghum genes and gene networks regulated by osmotic stress and hormonal treatment. We are providing an RNA-Seq data set and an initial collection of transcription factors, which offer a preliminary look into the cascade of global gene expression patterns that arise in a drought tolerant crop subjected to abiotic stress. These resources will allow scientists to query gene expression and functional annotation in response to drought.</p

State Of the Art Report in the fields of numerical analysis and scientific computing. Final version as of 16/02/2020 deliverable D4.1 of the HORIZON 2020 project EURAD.: European Joint Programme on Radioactive Waste Management

Document information Project Acronym EURAD Project Title European Joint Programme on Radioactive Waste Management Project Type European Joint Programme (EJP) EC grant agreement No. 847593 Project starting / end date 1 st June 2019-30 May 2024 Work Package No. 4 Work Package Title Development and Improvement Of NUmerical methods and Tools for modelling coupled processes Work Package Acronym DONUT Deliverable No. 4.

Fragments du monde (la poétique du nomadisme dans les oeuvres de Nicolas Bouvier et de kenneth White)

A travers l'étude des récits de voyage de l'écrivain suisse Nicolas Bouvier (1929-1998) et écossais Kenneth White (1936), le travail s'attache à définir les aspects de la nouvelle littérature de voyage, apparue en Angleterre et en France dans les dernières décennies du XXème siècle. La première partie esquisse la philosophie du voyage des deux auteurs. L'ouverture primordiale à l'expérience de la route chez Bouvier est mise en contraste avec le nomadisme intellectuel de White et à ses aspirations spirituelles (celtisme, chamanisme, grand Nord, orientalisme) qui aboutissent à un " espace blanc " multipolaire. La deuxième partie porte sur les différents aspects du processus de l'écriture : délai entre le voyage et l'écriture, typologie des récits (place du lecteur, différences d'approche pour les récits d'un voyage, d'un séjour), description du paysage (rôle de l'image, de l'humour), rôle de la poésie (haïku japonais, entre autre), comme l'expression suprême de l' " espace blanc ".Through the study of the travel books of Swiss writer Nicolas Bouvier (1929-1998) and Scottish writer Kenneth White (1936), the thesis aspires to define various aspects of the new travel literature, appeared in France and in England in the last decades of the XXth century. In the first section, the "philosophy" of travelling is draft. The primary openness to the road's experience of Bouvier is placed in opposition to the intellectual nomadism of White and to his spiritual orientations (celtism, shamanism, the Great North, orientalism) leading to a multipolar "white space". The second section shows various aspects of writing's process: interval between the travelling and the writing, typology of travel books (reader's role, different approach in the journey and stay description), representation of the landscape (writing-painting, role of the humour), role of the poetry (influence of haïku, among others) as the ultimate written expression of the "white space".PARIS3-BU (751052102) / SudocSudocFranceF

Training and mobility in EU projects EURAD and PREDIS

Knowledge management (KM) is critical to ensure safe and sustainable radioactive waste management. The European Commission is encouraging KM through the Waste Directive. EURAD and PREDIS are projects funded by the European Commission, including work packages devoted to Knowledge Management. EURAD has set up a “School of RWM”, launched in 2020. To establish a portfolio of training courses, currently existing training initiatives in the field of RWM were mapped. A gap analysis was carried out to detect current unfulfilled needs for courses on specific topics. The School of RWM has already organized two training courses responding to the perceived needs. Besides training courses, both projects regularly organize topical webinars, which are related to RWM & Predisposal-related themes. Both projects launched a dedicated mobility program, allowing their beneficiaries to perform technical visits to infrastructures, undertake internships and set up exchange programs between institutions within EURAD/PREDIS. In addition, PREDIS also financially supports participation in training courses and events. Finally, both projects support their respective student communities, including masters, Ph.D. students, and postdocs. In order to improve their efficiency, EURAD and PREDIS KM will be merged in the proposed upcoming EURAD-2 program