In situ synthesis of size-controlled, stable silver nanoparticles within ultrashort peptide hydrogels and their anti-bacterial properties

We have developed a silver-releasing biomaterial with promising potential for wound healing applications. The material is made of ultrashort peptides which can self-assemble in water to form hydrogels. Silver nanoparticles (Ag NPs) were synthesized in situ within the biomaterial, using only UV irradiation and no additional chemical reducing agents. The synthetic strategy allows precise control of the nanoparticle size, with the network of peptide fibers preventing aggregation of Ag NPs. The biomaterial shows increased mechanical strength compared to the hydrogel control. We observed a sustained release of Ag NPs over a period of 14 days. This is a crucial prerequisite for effective anti-bacterial therapy. The ability to inhibit bacterial growth was tested using different bacterial strains, namely gram-negative Escherichia coli and Pseudomonas aeruginosa and gram-positive Staphylococcus aureus. Inhibition of bacterial growth was observed for all strains. The best results were obtained for Pseudomonas aeruginosa which is known for exhibiting multidrug resistance. Biocompatibility studies on HDFa cells, using Ag NP-containing hydrogels, did not show any significant influence on cell viability. We propose this silver-releasing hydrogel as an excellent biomaterial with great potential for applications in wound healing due to its low silver content, sustained silver nanoparticle release and biocompatibility

Charge storage effects in Mylar resulting from electron irradiation, June 1965 - June 1966

Charge storage effects in Mylar from electron irradiatio

Rasch-progrediente Glomerulonephritis: Bewährte und neuere Therapieansätze

Zusammenfassung: Die rapid progrediente Glomerulonephritis (RPGN) ist als klinisches Syndrom durch die zeitliche Veränderung der Nierenfunktion definiert. Frühes Erkennen und sofortige immunsuppressive Behandlung verbessern die Prognose. Die Nierenbiopsie und die Autoantikörperserologie ermöglichen die genaue diagnostische Zuordnung der RPGN. Es werden ihre Einteilung aufgrund der Immunhistologie, der antineutrophil zytoplasmatische Antikörper (ANCA) und der antiglomerulären Basalmembran-Antikörper (anti-GBM) diskutiert. Anhand von Ergebnissen randomisiert kontrollierter Studien werden die Möglichkeiten der differenzierten Behandlung erläuter

Maximal multihomogeneity of algebraic hypersurface singularities

From the degree zero part of logarithmic vector fields along an algebraic hypersurface singularity we indentify the maximal multihomogeneity of a defining equation in form of a maximal algebraic torus in the embedded automorphism group. We show that all such maximal tori are conjugate and in one-to-one correspondence to maxmimal tori in the degree zero jet of the embedded automorphism group. The result is motivated by Kyoji Saito's characterization of quasihomogeneity for isolated hypersurface singularities and extends its formal version and a result of Hauser and Mueller.Comment: 5 page

The large scale gas and dust distribution in the galaxy: Implications for star formation

Infrared Astronomy Observations are presented for the diffuse infrared (IR) emissions from the galactic plane at wavelengths of 60 and 100 microns and the total far infrared intensity and its longitudinal variations in the disk were derived. Using available CO, 5 GHz radio-continuum, and HI data, the IR luminosity per hydrogen mass and the ingrared excess (IRE) ratio in the Galaxy were derived. The longitudinal profiles of the 60 and 100 micron emission were linearly decomposed into three components that are associated with molecular (H2), neutral (HI), and ionized (HII) phases in the interstellar medium (ISM), and the relevant dust properties were derived in each phase. Implications of the findings for various models of the diffuse IR emisison and for star formation in the galactic disk are discussed

Growth control of GaAs nanowires using pulsed laser deposition with arsenic over pressure

Using pulsed laser ablation with arsenic over pressure, the growth conditions for GaAs nanowires have been systematically investigated and optimized. Arsenic over pressure with As$_2$ molecules was introduced to the system by thermal decomposition of polycrystalline GaAs to control the stoichiometry and shape of the nanowires during growth. GaAs nanowires exhibit a variety of geometries under varying arsenic over pressure, which can be understood by different growth processes via vapor-liquid-solid mechanism. Single-crystal GaAs nanowires with uniform diameter, lengths over 20 $\mu$m, and thin surface oxide layer were obtained and can potentially be used for further electronic characterization

Rotational 3D Printing of Sensor Devices using Reactive Ink Chemistries

This paper charts progress in three key areas of a project supported by both UK government and UK industry to manufacture novel sensor devices using rotary 3D printing technology and innovative ink chemistries; (1) the development of an STL file slicing algorithm that returns constant Z height 2D contour data at a resolution that matches the given print head setup, allowing digital images to be generated of the correct size without the need for scaling; (2) the development of image transformation algorithms which allow images to be printed at higher resolutions using tilted print heads and; (3) the formulation of multi part reaction inks which combine and react on the substrate to form solid material layers with a finite thickness. A Direct Light Projection (DLP) technique demonstrated the robustness of the slice data by constructing fine detailed three dimensional test pieces which were comparable to identical parts built in an identical way from slice data obtained using commercial software. Material systems currently under investigation include plaster, stiff polyamides and epoxy polymers and conductive metallic’s. Early experimental results show conductivities of silver approaching 1.42x105 Siemens/m.Mechanical Engineerin

Submillimeter wavelength survey of the galactic plane from l = -5 deg to l = +62 deg: Structure and energetics of the inner disk

Results from a large scale survey of the first quadrant of the Milky Way galactic plane at wavelengths of 150, 250, and 300 microns with a 10x10 arcmin beam are presented. The emission detected in the survey arises from compact sources, most of which are identified with known peaks of 5 GHz and/or CO emission, and from an underlying diffuse background with a typical angular width of approximately 0.9 deg (FWHM) which accounts for most of the emission. A total of 80 prominent discrete sources were identified and characterized, of which about half were not previously reported at far infrared wavelengths. The total infrared luminosity within the solar circle is approximately 1 to 2x10 to the 10th power L sub 0, and is probably emitted by dust that resides in molecular clouds

A New Galactic Extinction Map of the Cygnus Region

We have made a Galactic extinction map of the Cygnus region with 5' spatial resolution. The selected area is 80^\circ to 90^\circ in the Galactic longitude and -4^\circ to 8^\circ in the Galactic latitude. The intensity at 140 \mum is derived from the intensities at 60 and 100 \mum of the IRAS data using the tight correlation between 60, 100, and 140 \mum found in the Galactic plane. The dust temperature and optical depth are calculated with 5' resolution from the 140 and 100 \mum intensity, and Av is calculated from the optical depth. In the selected area, the mean dust temperature is 17 K, the minimum is 16 K, and the maximum is 30 K. The mean Av is 6.5 mag, the minimum is 0.5 mag, and the maximum is 11 mag. The dust temperature distribution shows significant spatial variation on smaller scales down to 5'. Because the present study can trace the 5'-scale spatial variation of the extinction, it has an advantage over the previous studies, such as the one by Schlegel, Finkbeiner, & Davis, who used the COBE/DIRBE data to derive the dust temperature distribution with a spatial resolution of 1^\circ. The difference of Av between our map and Schlegel et al.'s is \pm 3 mag. A new extinction map of the entire sky can be produced by applying the present method.Comment: 27 pages, 14 figures, accepted for publication in Ap