Davranissal finans icin genisletilmis Lollapalooza etkisi onerisi : dopamin reseptorleri genoekonomide iyi bir aday mi?

PURPOSE: Since it was discovered that the main cause of market anomalies, which traditional theories are insufficient to explain, is human behavior, the eyes turned to behavioral theories have now started to search for the causes of these behavioral errors in very different disciplines. This search, which seems justified when it comes to human behavior, has pushed researchers to interdisciplinary studies and these studies have added new concepts to the literature. The Lollapalooza effect is one of these concepts. This concept, put forward by Charles Munger, can be expressed as the cause of behavioral anomalies, which are caused by the coexistence of more than one prejudice affecting human behavior, that turns the brain into mush. The aim of this study is to examine the behavioral biases of the Lollapalooza effect, as well as to demonstrate the inclusion of genetic factors for an extended Lollapalooza effect.FINDINGS: Looking at the results of the study, it is revealed that genetic information may be one of the reasons for economic and financial decisions. In addition, although there are many studies in the literature in which cognitive errors, which occur with the effect of psychological and sociological factors, are discussed individually and their causes and results are discussed in detail, it has been revealed that the causes and consequences of considering all of them together should be investigated.IMPORTANCE OF THE STUDY: Since dopamine receptor genes are known to be closely related to human behavior, it is clear that these genes can expand the limits of lollapalooza effect in financial decisions. In this way, it is revealed that the causes and consequences of investor behavior should be addressed not only psychologically, but also genetically and even neurologically.peer-reviewe

Evaluating unspecific oxidative stress parameters in the sera of patients with irritable bowel syndrome

Objective: Irritable bowel syndrome (IBS) is a common global condition characterized by abdominal pain and alterations in bowel habits not caused by other organic diseases and its etiopathogenesis has not been elucidated. In this study, we aimed to evaluate the oxidative stress parameters in patients with IBS. Materials and methods: Fifty patients diagnosed with IBS using the Rome III criteria and a control group of 50 healthy subjects were included in the study. Oxidative stress parameters including total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) values were analyzed from all study subjects. Results: Compared to the controls; the TOS and OSI values were significantly higher, and the TAS value was significantly lower in IBS patients (p < 0.001 for all). Conclusions: In present study we demonstrated that oxidative stress increased and antioxidant capacity decreased in IBS, and antioxidants might be beneficial in the supportive treatment for IBS

Isolation and identification of bacillus pumilus yhh-2, a potential pathogen to the alfalfa weevil (Hypera postica gyllenhal)

Alfalfa weevil (Hypera postica Gyllenhal, 1813) samples were collected from different locations in Kırşehir, Turkey, during May–August in 2014. They were immediately transferred to the research laboratory and dissected under aseptic conditions. Then serial dilutions were prepared from digestive tract samples and the spread plate technique was used for obtaining pure cultures. The conventional and molecular methods that include morphological and physiological examinations, biochemical tests, 16S rDNA sequencing, and the basic local alignment search tool (BLAST) were used for identification of the bacterial isolates. According to the findings of the present study, the YHH-2 isolate was found as the main pathogenic bacterium that dominates the digestive tract microflora of the alfalfa weevil. 16S rDNA sequencing and the BLAST data revealed that YHH-2 showed 100% similarity to Bacillus pumilus, recently described as an entomopathogenic strain. In conclusion, the results of the present study are important due to showing for the first time the presence of Bacillus pumilus YHH-2 in the digestive tract of the alfalfa weevil and it may be used as a potential biocontrol agent against the harmful effects of this insect species. © TÜBİTAK

A nationwide multicentre study in Turkey for establishing reference intervals of haematological parameters with novel use of a panel of whole blood

IntroductionA nationwide multicentre study was conducted to establish well-defined reference intervals (RIs) of haematological parameters for the Turkish population in consideration of sources of variation in reference values (RVs). Materials and methodsK2-EDTA whole blood samples (total of 3363) were collected from 12 laboratories. Sera were also collected for measurements of iron, UIBC, TIBC, and ferritin for use in the latent abnormal values exclusion (LAVE) method. The blood samples were analysed within 2 hours in each laboratory using Cell Dyn and Ruby (Abbott), LH780 (Beckman Coulter), or XT-2000i (Sysmex). A panel of freshly prepared blood from 40 healthy volunteers was measured in common to assess any analyser-dependent bias in the measurements. The SD ratio (SDR) based on ANOVA was used to judge the need for partitioning RVs. RIs were computed by the parametric method with/without applying the LAVE method. ResultsAnalyser-dependent bias was found for basophils (Bas), MCHC, RDW and MPV from the panel test results and thus those RIs were derived for each manufacturer. RIs were determined from all volunteers’ results for WBC, neutrophils, lymphocytes, monocytes, eosinophils, MCV, MCH and platelets. Gender-specific RIs were required for RBC, haemoglobin, haematocrit, iron, UIBC and ferritin. Region-specific RIs were required for RBC, haemoglobin, haematocrit, UIBC, and TIBC. ConclusionsWith the novel use of a freshly prepared blood panel, manufacturer-specific RIs’ were derived for Bas, Bas%, MCHC, RDW and MPV. Regional differences in RIs were observed among the 7 regions of Turkey, which may be attributed to nutritional or environmental factors, including altitude

Evaluation of Law no.6306 from Perspective of Public Spaces – Gezi Park Case

Cities in Turkey, especially Istanbul are under pressure of national and international capital flows which are assigned by free market economy and globalization processes. While the pressure results in partial urban development far from integrated approach, an alternative idea advocating public space has been seen as tilt at windmills. However, a paradigm supporting public place led planning and design and taking public space and public interest forefront in the face of social segregation has been an important issue while legal and administrative arrangements are also very crucial in terms of practicality. This article aims to present the transformation of urban public spaces and define the effects of legal instruments to this transformation. In that context, firstly transformation of public space during historical process is clarified. In that sense, the concept of urban transformation which has become a worldwide vital issue on renewing the city parts suffering from physical and social deterioration is examined comprehensively in Turkish context. After the former processes and legal instruments concerning urban transformation are evaluated, the last approved act called as Law No. 6306 on Transformation of Areas Under Disaster Risk is examined in detail in terms of public ownership and public space approach. In this regard, it is concluded by the study that the law no. 6306 puts the existence of public space and public ownership into risk. On the other hand, it is also seen that conducted urban transformation projects are mostly disconnected from general plans and built without considering social and economic aspects because of market oriented planning, capital flows and partial planning which cause greater problems by creating short term solutions instead of long term. When the Gezi Park process and related questionnaires conducted for the study are evaluated, it is possible to see that public space perception of society changed drastically while the awareness has risen. However, defining public space and its ownership is still such a complicated task for citizens. On the other hand, it can be said that society can be a part of public space only when its freedom of thought and expression about urban problems and public interest are assured. Nowadays, preserving public space in our cities developing through free market conditions will be only possible if society could be a part of it and legal instruments can be revised for that purpose.Cities in Turkey, especially Istanbul are under pressure of national and international capital flows which are assigned by free market economy and globalization processes. While the pressure results in partial urban development far from integrated approach, an alternative idea advocating public space has been seen as tilt at windmills. However, a paradigm supporting public place led planning and design and taking public space and public interest forefront in the face of social segregation has been an important issue while legal and administrative arrangements are also very crucial in terms of practicality. This article aims to present the transformation of urban public spaces and define the effects of legal instruments to this transformation. In that context, firstly transformation of public space during historical process is clarified. In that sense, the concept of urban transformation which has become a worldwide vital issue on renewing the city parts suffering from physical and social deterioration is examined comprehensively in Turkish context. After the former processes and legal instruments concerning urban transformation are evaluated, the last approved act called as Law No. 6306 on Transformation of Areas Under Disaster Risk is examined in detail in terms of public ownership and public space approach. In this regard, it is concluded by the study that the law no. 6306 puts the existence of public space and public ownership into risk. On the other hand, it is also seen that conducted urban transformation projects are mostly disconnected from general plans and built without considering social and economic aspects because of market oriented planning, capital flows and partial planning which cause greater problems by creating short term solutions instead of long term. When the Gezi Park process and related questionnaires conducted for the study are evaluated, it is possible to see that public space perception of society changed drastically while the awareness has risen. However, defining public space and its ownership is still such a complicated task for citizens. On the other hand, it can be said that society can be a part of public space only when its freedom of thought and expression about urban problems and public interest are assured. Nowadays, preserving public space in our cities developing through free market conditions will be only possible if society could be a part of it and legal instruments can be revised for that purpose

Characterization of a highly pathogenic Bacillus thuringiensis strain isolated from common cockchafer, Melolontha melolontha

Demirbag, Zihni/0000-0001-5487-1977WOS: 000246813500006PubMed: 17575913A bacterial isolate (Mm2) of Melolontha melolontha was identified and characterized. Based on various morphological, physiological, biochemical and molecular characteristics, it was identified as Bacillus thuringiensis subsp. tenebrionis. This isolate was compared to the reference strains by electron microscopy, SDS-PAGE analysis, plasmid pattern, cry gene content and insecticidal activity. Cells of the isolate harbored flat square inclusions containing a protein component of approximate to 65 kDa. After trypsin digestion of solubilized crystals, SDS-PAGE resolved a unique proteinase-resistant peptide of approximate to 50 kDa. Plasmid pattern showed similar bands to those of the reference strain, PCR analysis showed that the isolate has cry3 gene. Toxicity tests (against 5 coleopteran species) showed 80% insecticidal activity against the larvae of M. melolontha. The isolate Mm2 may be valuable as biological control agent for M melolontha and other coleopteran insects

Purification and Characterization of the Bacteriocin Thuricin Bn1 Produced by Bacillus thuringiensis subsp kurstaki Bn1 Isolated from a Hazelnut Pest

Demirbag, Zihni/0000-0001-5487-1977WOS: 000315547800006PubMed: 23412058A novel bioactive molecule produced by Bacillus thuringiensis subsp. kurstaki Bn1 (Bt-Bn1), isolated from a common pest of hazelnut, Balaninus nucum L. (Coleoptera: Curculionidae), was determined, purified, and characterized in this study. The Bt-Bn1 strain was investigated for antibacterial activity with an agar spot assay and well diffusion assay against B. cereus, B. weinhenstephenensis, L. monocytogenes, P savastanoi, P syringae, P lemoignei, and many other B. thuringiensis strains. The production of bioactive molecule was determined at the early logarithmic phase in the growth cycle of strain Bt-Bn1 and its production continued until the beginning of the stationary phase. The mode of action of this molecule displayed bacteriocidal or bacteriolytic effect depending on the concentration. The bioactive molecule was purified 78-fold from the bacteria supernatant with ammonium sulfate precipitation, dialysis, ultrafiltration, gel filtration chromatography, and HPLC, respectively. The molecular mass of this molecule was estimated via SDS-PAGE and confirmed by the ESI-TOF-MS as 3,139 Da. The bioactive molecule was also determined to be a heat-stable, pH-stable (range 6-8), and proteinase K sensitive antibacterial peptide, similar to bacteriocins. Based on all characteristics determined in this study, the purified bacteriocin was named as thuricin Bn1 because of the similarities to the previously identified thuricin-like bacteriocin produced by the various B. thuringiensis strains. Plasmid elution studies showed that gene responsible for the production of thuricin Bn1 is located on the chromosome of Bt-Bn1. Therefore, it is a novel bacteriocin and the first recorded one produced by an insect originated bacterium. It has potential usage for the control of many different pathogenic and spoilage bacteria in the food industry, agriculture, and various other areas.TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110T030]The Authors thank Dr. Daniel R. Zeigler (BGSC, Bacillus Genetic Stock Center) for the generous gift of bacteriocinogenic strains of B. thuringiensis and B. cereus. The Authors also wish to thank Dr. Halil Ibrahim Ugras (Giresun University, Turkey) for helping with the ESI-TOF-MS analysis. This work was supported by TUBITAK (110T030)

A highly pathogenic strain of Bacillus thuringiensis serovar kurstaki in lepidopteran pests

Nalcacioglu, Remziye/0000-0003-0527-9541; Demirbag, Zihni/0000-0001-5487-1977WOS: 000252058900013PubMed: 18176540In order to detect and identify the most toxic Bacillus thuringiensis strains against pests, we isolated a B. thuringiensis strain (Bn1) from Balaninus nucum (Coleoptera: Curculionidae), the most damaging hazelnut pest. Bn1 was characterized via morphological, biochemical, and molecular techniques. The isolate was sero-typed, and the results showed that Bn1 was the B. thuringiensis serovar, kurstaki (H3abc). The scanning electron microscopy indicated that Bn1 has crystals with cubic and bipyramidal shapes. The Polymerase Chain Reactions (PCRs) revealed the presence of the cry1 and cry2 genes. The presence of Cry1 and Cry2 proteins in the Bn1 isolate was confirmed via SDS-PAGE, at approximately 130 kDa and 65 kDa, respectively. The bioassays conducted to determine the insecticidal activity of the Bn1 isolate were conducted with four distinct insects, using spore-crystal mixtures. We noted that Bn1 has higher toxicity as compared with the standard B. thuringiensis subsp. kurstaki (HD-1). The highest observed mortality was 90% against Malacosoma neustria and Lymantria dispar larvae. Our results show that the B. thuringiensis isolate (Bn1) may prove valuable as a significant microbial control agent against lepidopteran pests

High insecticidal activity of Leclercia adecarboxylata isolated from Leptinotarsa decemlineata (Col.: Chrysomelidae)

Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say), is an important pest on solanaceous crops worldwide. CPB has developed resistance to insecticides used for its control. In this study, in order to find a more effective and safer biological control agent against L. decemlineata, we studied the bacterial flora of CPB, and tested them for insecticidal effects on it. The highest insecticidal effect determined on L. decemlineata within 5 days was 100% and this effect was exhibited by Ld1 isolate. According to the morphological, physiological and biochemical tests, and 16S rRNA sequence homologies, Ld1 was identified as Leclercia adecarboxylata. This is the first time that this bacterium has been isolated from any insect pests. Our results indicate that Lecl. adecarboxylata may be valuable as a biological control agent for L. decemlineata