47 research outputs found
HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer
- Author
- Absar Mohammed
- Abson Charlotte
- Adams Jocelyn
- Adamson Douglas
- Adelekan Matthew
- Agarwal Roshan
- Alataki Anastasia
- Algurafi Hafiz
- Allerton Rozenn
- Anand Ambika
- Ashkanani Fawzia
- Babu Ed
- Ball Adrian
- Barrett Jane
- Barthelmes Ludger
- Barthkur Urmila
- Bergamino Milana A
- Bews-Hair Maria
- Bhaskar Pudhupalayam
- Bhattacharyya Madhumita
- Bliss Judith M
- Bonom Riccardo
- Bramley Maria
- Brown Victoria Alexandra
- Bundred Nigel
- Burcombe Russell
- Carr Michael
- Chakrabarti Amitabha
- Chan Charlie
- Chan Stephen
- Chandrasekharan Sankaran
- Chatterjee Sumohan
- Cheang Maggie CU
- Chin Kian
- Churn Mark
- Cleator Susan
- Coleman Rob
- Corder Allan
- Crane Peter
- Crawford Derek
- Crellin Perric
- Crowley Clare
- Cunnick Giles
- Cutress Ramsay
- Davis Ruth
- Dawson Jonathan
- Donnelly Jull
- Donnelly Peter
- Doughty Julie
- Dowsett Mitch
- Dunn Kathleen
- Dyke Gary
- Ellenbogen Simon
- Evans Abigail
- Ferguson Douglas
- Forrest Jennifer
- Fox John
- Gallegos Nicholas
- Gilbert .
- Goranova Rebecca
- Grieve Robert
- Griffith Clive
- Hadaki Maher
- Hamed Hisham
- Harding-Mackean Claudia
- Hatcher Olivia
- Hatton Matthew
- Hills Margaret
- Hinton Christopher
- Hoar Fiona
- Hogg Martin
- Holcombe Chris
- Holcombe Christopher
- Hollywood Ciaran
- Holt Simon
- Holt Simon
- Holt Steve
- Horgan Kieran
- Hwang David
- Hyett Elaine
- Iqbal Shabana
- Irvine Tracey
- Johnson Richard
- Johnson Tayo
- Johnston Stephen
- Johri Akhil
- Jones Alison
- Kelleher Muireann
- Kennedy Robert
- Kenny Frances
- Khattak Ilyas
- Kilburn Lucy
- Kishore Makam
- Kissin Mark
- Kneeshaw Peter
- Kokan Jalal
- Kothari Ashutosh
- Kovacs Tibor
- Laidlaw Ian
- Laws Siobhan
- Ledwidge Serena
- Lee Caroline
- Leonard Robert
- Lewanski Conrad
- Linforth Rick
- López-Knowles Elena
- Maxwell William
- McFall Brendan
- McIntosh Stuart
- Mehra Rakesh
- Modi Anupam
- Morani Gabriele
- Mortimer Caroline
- Muralikrishna Vummiti
- Murphy Claire
- Naik Jay Dolatrai
- Narayanan Sankaran
- Nejim Ali
- Newby Jacqueline
- Ornstein Marcus
- Pain Simon
- Parmar Jitendra
- Parton Marina
- Patel Ashraf
- Pope Vanessa
- Prasad Ramachandran
- Prof Highes-Davies
- Quigley Mary
- Ravichandran Duraisamy
- Rea Daniel
- Rees-Lee Jacqueline
- Reichert Robert
- Roberts Jonathan
- Robertson John F
- Robinson Anne
- Roylance Rebecca
- Salman Reem Ramzi
- Samra Walid
- Schuster Eugene F
- Seetharam Seema
- Sharif Muhammad
- Sharma Ravi
- Shere Michael
- Sibbering Mark
- Silva Shobha
- Sinha Prakash
- Skene Anthony
- Skene Anthony
- Smith Ian
- Smith Ian E
- Smith Simon
- Soulsby Racheal
- Sparrow Geoffrey
- Sutton Richard
- Sweetland Helen
- Thakur Kislaya
- Thekkinkattil Dinesh
- Thomson Simon
- Thorne Amanda
- Thrush Steven
- Todd Radha
- Tovey Holly
- Usman Tamoor
- Vaidya Jayant
- Vesty Sarah
- Vidya Raghavan
- Wahee Shamaela
- Walji Nawaz
- Walker Philip
- Wheatley Duncan
- Williams Michael
- Williams Nicholas
- Winter Matthew
- Winters Zoe
- Wyld Lynda
- Xiao Hui
- Publication venue
- 'Elsevier BV'
- Publication date
- 16/08/2022
- Field of study
BACKGROUND: Oestrogen receptor positive/ human epidermal growth factor receptor positive (ER+/HER2+) breast cancers (BCs) are less responsive to endocrine therapy than ER+/HER2- tumours. Mechanisms underpinning the differential behaviour of ER+HER2+ tumours are poorly characterised. Our aim was to identify biomarkers of response to 2 weeks’ presurgical AI treatment in ER+/HER2+ BCs. METHODS: All available ER+/HER2+ BC baseline tumours (n=342) in the POETIC trial were gene expression profiled using BC360™ (NanoString) covering intrinsic subtypes and 46 key biological signatures. Early response to AI was assessed by changes in Ki67 expression and residual Ki67 at 2 weeks (Ki672wk). Time-To-Recurrence (TTR) was estimated using Kaplan-Meier methods and Cox models adjusted for standard clinicopathological variables. New molecular subgroups (MS) were identified using consensus clustering. FINDINGS: HER2-enriched (HER2-E) subtype BCs (44.7% of the total) showed poorer Ki67 response and higher Ki672wk (p<0.0001) than non-HER2-E BCs. High expression of ERBB2 expression, homologous recombination deficiency (HRD) and TP53 mutational score were associated with poor response and immune-related signatures with High Ki672wk. Five new MS that were associated with differential response to AI were identified. HER2-E had significantly poorer TTR compared to Luminal BCs (HR 2.55, 95% CI 1.14–5.69; p=0.0222). The new MS were independent predictors of TTR, adding significant value beyond intrinsic subtypes. INTERPRETATION: Our results show HER2-E as a standardised biomarker associated with poor response to AI and worse outcome in ER+/HER2+. HRD, TP53 mutational score and immune-tumour tolerance are predictive biomarkers for poor response to AI. Lastly, novel MS identify additional non-HER2-E tumours not responding to AI with an increased risk of relapse
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
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- Baker Richard
- Bakis Michele
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- Bao Qiyu
- Bao Weidong
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- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
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- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
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- Beare David
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- Hillier LaDeana
- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
- Holden Jane
- Holdgate Janet
- Hollaway Mara
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- Holmes Andrea
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- Holmes Sarah
- Holroyd Simon
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- Holtzer Caleb
- Homsi Deana K.
- Homsi Farah J.
- Honan Tracy
- Hood Leroy
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- Hornsby Geoff
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- Hosoda Kei
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- Hosseini Roya
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- Howard Philip
- Howard Stephanie R.
- Howden Philip
- Howe Kevin
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- Howell Latoya Lynette
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- Huang Fang
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- Huang Wei
- Huang Wei
- Huang Zhengping
- Hubbard Timothy
- Huber James W.
- Huckle Elizabeth
- Hue Heather
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- Hughes Jennifer
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- Hunter Rov, II
- Hupman Matt
- Huynh Sandy
- Hyde David
- Hynds Christopher
- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
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- Ince Michael
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- Isherwood Judith
- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Iwatate Mariko
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- Izatt Janet
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- Izumiyama Tomohiro
- Jacintho Mark
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- Jackson Terri
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- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
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- Jeffery Grant
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- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
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- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
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- Kremmidiotis Gabriel
- Krogh Anders
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- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
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- Lambart Christine
- Lamble Ralph
- Lamerdin Jane E.
- Lander Eric S.
- Landers Tom
- Langford Cordelia
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- Lapidus Alla
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- Lewis Keith
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- Leyba Tina
- Li Changfeng
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- Lieuallen Kim
- Lightning Julia
- Lim Meng K.
- Lindblad-Toh Kerstin
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- Longmire Johnathan L.
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- Lorensuhewa Lorna M.
- Lou Yunian
- Loulseged Hermela
- Loveland Jane
- Lovell Jamie
- Lovett Demetria A.
- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
- Lu Tao
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- Lu Yongxiang
- Lu Yontao T.
- Lu Yue
- Lucas Robert
- Lucas Susan
- Lucier Alice
- Lucier Raymond L.
- Ludeman Thom
- Lui Annie
- Lundgren Lyndsey
- Luo Chunqing
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
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- Manohar Chitra
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- Mardis Elaine R.
- Mareth David
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- Marinelli Lisa
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- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
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- Matthews Charles D.
- Matthews Lucy
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- Matthews Sterling D.
- Mauceli Evan
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- McMurray Kimberly
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- Miner Sheri
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- Minja Emmanuel
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- Minx Patrick J.
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- Morgan Margaret B.
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- Mu Feng
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- Mullenger Ian
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- Mulrain Leon
- Munday Brian
- Munday Elaine
- Mundt Mark O.
- Mungall Andy
- Munidasa Mala
- Munk A. Christine
- Munk Christie A.
- Munson Glen
- Murakami Katsuhiko
- Murayama Yuji
- Murnane Clare
- Murphy Matthew B.
- Murphy Michael
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- Nagao Syunsuke
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- Nair Latha
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- Naka Maho
- Nakagawa Masayo
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- Nelson Joanne
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- Newes Christian
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- Ng Bee
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- Nguyen Natalie M.
- Nguyen Ngoc Bich
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- Ning Zemin
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- Nordsiek Gabriele
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- Nowlin Larry
- Nusbaum Chad
- Nwaokelemeh Ogechi O.
- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
- O\u27Leary Sinead
- O\u27Loughlin Jennifer
- O\u27Neill Keith
- Obayashi Izumi
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- Ohno Saho
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- Okoawo Ose
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- Oragunye Njideka
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- Parry-Brown Ginny
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- Perez Agapito
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- Sasaki Takashi
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- Scarpelli Claude
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- Scherer Steven Edward
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- Sonnhammer Erik
- Sonnhammer Erik
- Sorelle Richard P.
- Sotheran Elizabeth
- Sougnez Carrie
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- Sparks Anastasia L.
- Spencer Brian
- Spieth John
- Spooner William
- Spraggon Lee
- Sqaures Suzanna
- Squares Janet
- Stabenau Arne
- Stables Michael
- Stalker James
- Stalker John
- Stallings Raymond I.
- Stalvey Malinda
- Stamford Steve
- Stammers Melanie
- Standring Lisa
- Stange-Thomann Nicole
- Stavropoulos Sharon
- Steffen David
- Stege Justin T.
- Steingruber Helen
- Stephens Yvonne
- Stephens-Bolds Shaela
- Stetson Kevin
- Stevko Victor
- Steward Charles
- Stewart Aengus
- Stewart Michael
- Still Ian
- Stock Mo
- Stone Casey
- Stone Evan
- Stone Sabrina
- Stoppard Lisa
- Storey Philip
- Storey Roy
- Stowe Sarah
- Strachan Carol
- Strachan Greg
- Strasser Jonathan
- Stribling Claire
- Strong Cynthia
- Stubbs Lisa
- Stubbs Matthew
- Stultz Janet
- Sturdy John
- Su Xiaohu
- Subramanian Sandhya
- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
- Summers Leslie J.
- Sun Hui
- Sun Jiajia
- Sun Jiandong
- Sun Jiu Qin
- Sun Min
- Sun Tao
- Sun Wei
- Sun Yongqiao
- Sun Yu
- Sun Yue
- Sutherland Grant R.
- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
- Svetz Leah Anne
- Swainson Chris
- Swann Mark
- Swarbreck David
- Swearengen-Shahid Sharhonda
- Sycamore Neil
- Ségurens Béatrice
- Tabor Paul E.
- Tacey Kristina
- Tagett Beckie
- Tagney Matthew
- Tahara Takashi
- Takahashi Keiko
- Takano Nobuhiro
- Takaoka Tori
- Takayanagi Atsushi
- Takenaka Tracy
- Talamas Jessica
- Tam Serena
- Tamerisa Kavitha S.
- Tamirisa Aparna
- Tan Olivia
- Tan Steven
- Tan Xinyu
- Tan Xinyu
- Tang Hongli
- Tang Xiangjun
- Tansey Jennifer
- Tao Ran
- Tapia Roxanne
- Taring Elizabeth
- Tatsuyama Miho
- Tatum Owatha I.
- Taudien Stefan
- Taylor Amy
- Taylor Christina C.
- Taylor Gillian
- Taylor Kate
- Taylor Ruth
- Taylor Sam
- Taylor Susan
- Taylor Tineace R.
- Taylor Todd Duane
- Tchuinga Pierre
- Tee Louise
- Telford Ethan Brett
- Tenzin Pema
- Terada Yoriko
- Terry Astrid
- Tesfaye Senait
- Tesmer Judith G.
- Tester Julieanne
- Thayer Nina
- Theaker Andrew
- Theil James
- Theodore Joumathe
- Thexton David
- Thies Stephanie
- Thomas Craig
- Thomas Daniel
- Thomas Daryl J.
- Thomas Karen
- Thomas Nicole
- Thomas Paulette
- Thomas Ruth
- Thomas Shereen
- Thommai Roselin
- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
- Tromans Anthony
- Trong Stephan
- Trumbower Heather
- Tsai Ming
- Tsamla Tsamla
- Tsolas Jason
- Tsomo Nawang
- Tsujimoto Susan
- Tsukamoto Yumi
- Tsuruoka Hiromi
- Tsuzuki Rina
- Tu Yuefeng
- Tu Yuefeng
- Tubby Ben
- Tufarelli Cristina
- Turner Heidi
- Turney Kathryn
- Tynan Katherine
- Ueland Stephanie
- Ueng Samantha
- Ukegbu Ogechi Nkemdirim
- Ulanovsky Levy E.
- Un Chun
- Ung Quyen
- Upson Darren
- Urban Jeremy B.
- Ureta-Vidal Abel
- Ureta-Vidal Abel
- Usmani Kamran
- Ustaszewska Anna
- Uyama Nozomi
- Valas Ruben E.
- Valdez Michelle
- Valle Duane
- Valles Yvonne
- Van Brunt Andrew
- Van Dilla Marvin
- Van Helmond Zoe
- Van Luchene Ryan
- Vardanian Zachary
- Vargas Michelle
- Vargo Charles E.
- Vartanian Steffan
- Vasquez Lydia I.
- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
- Veil Rose
- Veklerov Eugene
- Velasco Nelson
- Velasquez Lisa
- Venkataranan Vijay
- Vera Virginia A.
- Verduzco Daniel
- Vergez Lisa
- Vico Virginie
- Viknaraja Ramya
- Villasana Donna M.
- Vine Wendy
- Viswanathan Vijay
- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
- Wang Chunyan
- Wang Dong
- Wang Feng
- Wang Guangxin
- Wang Guihai
- Wang Guihai
- Wang Hongjuan
- Wang Hongwei
- Wang Huanjie
- Wang Huifeng
- Wang Huifeng
- Wang Jian
- Wang Jian
- Wang Jian
- Wang Jie
- Wang Jing
- Wang Jingqiang
- Wang Jingqiang
- Wang Jinhua
- Wang Joann
- Wang Juan
- Wang Jun
- Wang Jun
- Wang Jun
- Wang Li
- Wang Lijie
- Wang Lijuan
- Wang Lijun
- Wang Ling
- Wang Liqun
- Wang Mei
- Wang Qiaoyan
- Wang Shifen
- Wang Shu
- Wang Suzhen
- Wang Wenjun
- Wang Xiaoling
- Wang Xiaoning
- Wang Xuefei
- Wang Xuegang
- Wang Yan
- Wang Yimin
- Wang Ying
- Wang Ying
- Wang Yuanyuan
- Wangchuck Tsering
- Wangdi Tsering
- Ward-Moore Stephanie
- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
- Watt Nicola
- Webb Anthony
- Webb Jeannette
- Webber Caleb
- Weber Ryan J.
- Wehri Edward
- Wei Shulin
- Wei Xuehong
- Weidenbach Richard
- Weinstock George
- Weinstock Keith
- Weir John
- Weissenbach Jean
- Wells Alan
- Wells Sarah
- Welton Robert
- Wen Gaiping
- Wendi Mike
- Weng Li
- Wenning Sarah
- Wentz Sara
- Werler Daniela
- Wesley Mary Melissa
- West Paul
- West Tony
- Wetterstrand Kris
- Wheatley Angela
- Wheatley Carl
- Wheeler David A.
- Wheeler Gideon
- Wheeler Jeremy
- Whitaker Hayley
- White Adam
- White Amelia
- White Brian
- White Catherine
- White Flower
- White Jennifer
- White Johnathon
- White P. Scott
- White Scott P.
- White Simon
- Whitehead Sally
- Whiteley Matthew
- Whitmore Scott
- Whittaker Adam
- Whittaker Charles
- Whittaker Pamela
- Wickremasinghe Manosha I.
- Widaa Sara
- Wiegel Sarah
- Wild Anna
- Wilkinson Jane
- Wilkinson Jane
- Wilkinson Paul
- Willey David
- Williams Albert L.
- Williams Andy
- Williams Bill
- Williams Gabrielle A.
- Williams Leanne
- Williamson Angela L.
- Williamson Helen
- Wills Patricia L.
- Wills Richard
- Wilmer Tamsin
- Wilming Laurens
- Wilson Brian
- Wilson Gareth
- Wilson Margaret
- Wilson Nyree
- Wilson Piers
- Wilson Richard K.
- Wilson Siobhan
- Wilson Steve
- Wilson Wendy
- Wincker Patrick
- Window Philip
- Winster Jenny
- Winzar Claire
- Witt James
- Wleczyk Regina
- Wobus Fred
- Woessner Jeffrey
- Wohldmann Patty
- Wollard Jessica
- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
- Woods Eric
- Woodwark Cara
- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
- Wright Charmain
- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Insights into the binding properties of a cuprous ion embedded in the tren cap of a calix[6]arene and supramolecular trapping of an intermediate
- Author
- Publication venue
- 'Royal Society of Chemistry (RSC)'
- Publication date
- 01/01/2007
- Field of study
Improving social justice in observational studies : protocol for the development of a global and Indigenous STROBE-equity reporting guideline
- Author
- Akl Elie A.
- Antequera Alba
- Avey Marc T.
- Bhutta Zulfiqar A
- Chamberlain Catherine
- Craig Peter
- Cuervo L.G
- Dewidar Omar
- Dicko Alassane
- Ellingwood Holly
- Feng Cindy
- Francis Damian
- Funnell Sarah
- Ghogomu Elizabeth
- Greer-Smith Regina
- Hardy Billie-Jo
- Harwood Matire
- Hatcher-Roberts Janet
- Horsley Tanya
- Juando-Prats Clara
- Jull Janet
- Kasonde Mwenya
- Kennedy Michelle
- Kredo Tamara
- Krentel Alison
- Kristjansson Elizabeth
- Langer Laurenz
- Lawson Daeria O
- Lesperance Miranda
- Little Julian
- Loder Elizabeth
- Magwood Olivia
- Mahande Michael Johnson
- Mbuagbaw Lawrence
- Melendez-Torres G.J.
- Moore Ainsley
- Niba Loveline Lum
- Nicholls Stuart G.
- Nkangu Miriam Nguilefem
- Obuku Ekwaro
- Okwen Patrick
- Pantoja Tomas
- Petkovic Jennifer
- Petticrew Mark
- Pottie Kevin
- Rader Tamara
- Ramke Jacqueline
- Riddle Alison
- Rizvi Anita
- Shamseer Larissa
- Sharp Melissa
- Shea Bev
- Tanuseputro Peter
- Tufte Janice
- Tugwell Peter
- Von Elm Erik
- Waddington Hugh Sharma
- Wang Harry
- Wang Xiaoqin
- Weeks Laura
- Welch Vivian
- Wells George
- White Howard
- Wiysonge Charles Shey
- Wolfenden Luke
- Young Taryn
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Altres ajuts: Canadian Institutes of Health Research (CIHR), grant number 173269.Background: Addressing persistent and pervasive health inequities is a global moral imperative, which has been highlighted and magnified by the societal and health impacts of the COVID-19 pandemic. Observational studies can aid our understanding of the impact of health and structural oppression based on the intersection of gender, race, ethnicity, age and other factors, as they frequently collect this data. However, the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline, does not provide guidance related to reporting of health equity. The goal of this project is to develop a STROBE-Equity reporting guideline extension. Methods: We assembled a diverse team across multiple domains, including gender, age, ethnicity, Indigenous background, disciplines, geographies, lived experience of health inequity and decision-making organizations. Using an inclusive, integrated knowledge translation approach, we will implement a five-phase plan which will include: (1) assessing the reporting of health equity in published observational studies, (2) seeking wide international feedback on items to improve reporting of health equity, (3) establishing consensus amongst knowledge users and researchers, (4) evaluating in partnership with Indigenous contributors the relevance to Indigenous peoples who have globally experienced the oppressive legacy of colonization, and (5) widely disseminating and seeking endorsement from relevant knowledge users. We will seek input from external collaborators using social media, mailing lists and other communication channels. Discussion: Achieving global imperatives such as the Sustainable Development Goals (e.g., SDG 10 Reduced inequalities, SDG 3 Good health and wellbeing) requires advancing health equity in research. The implementation of the STROBE-Equity guidelines will enable a better awareness and understanding of health inequities through better reporting. We will broadly disseminate the reporting guideline with tools to enable adoption and use by journal editors, authors, and funding agencies, using diverse strategies tailored to specific audiences
A scoping review establishes need for consensus guidance on reporting health equity in observational studies
- Author
- Antequera Alba
- Avey Marc T.
- Bhutta Zulfiqar
- Chamberlain Catherine
- Craig Peter
- Cuervo Luis Gabriel
- Desai Payaam
- Dewidar Omar
- Doyle Rebecca
- Elizabeth Jull Janet
- Ellingwood Holly
- Feng Cindy
- Funnell Sarah
- Ghogomu Elizabeth
- Hardy Billie-Jo
- Hatcher-Roberts Janet
- Horsley Tanya
- Huang Jimmy
- Juando-Prats Clara
- Kasonde Mwenya
- Kredo Tamara
- Krentel Alison
- Kristjansson Elizabeth
- Lawson Daeria O.
- Little Julian
- Magwood Olivia
- Mahande Michael Johnson
- Martel Andrea
- Mbuagbaw Lawrence
- Niba Loveline Lum
- Nicholls Stuart G.
- Nkangu Miriam
- Noorduyn S.G.
- Obuku Ekwaro A.
- Pantoja Tomas
- Rader Tamara
- Ramke Jacqueline
- Rizvi Anita
- Sharp Melissa K.
- Shea Beverley
- Tufte Janice
- Tugwell Peter
- von Elm Erik
- Waddington Hugh Sharma
- Wang Harry
- Wang Xiaoqin
- Weeks Laura
- Welch Vivian A.
- Wiysonge Charles S.
- Wolfenden Luke
- Young Taryn
- Publication venue
- 'Elsevier BV'
- Publication date
- 15/06/2023
- Field of study
Objective
To evaluate the support from the available guidance on reporting of health equity in research for our candidate items and to identify additional items for the STROBE (Strengthening Reporting of Observational studies in Epidemiology)-Equity extension.
Study design and setting
We conducted a scoping review by searching Embase, MEDLINE, CINAHL, Cochrane Methodology Register, LILACS, and Caribbean Centre on Health Sciences Information up to January 2022. We also searched reference lists and grey literature for additional resources. We included guidance and assessments (hereafter termed “resources”) related to conduct and/or reporting for any type of health research with or about people experiencing health inequity.
Results
We included thirty-four resources, which supported one or more candidate items or contributed to new items about health equity reporting in observational research. Each candidate item was supported by a median of six (range: 1 - 15) resources. In addition, 12 resources suggested 13 new items, such as “report the background of investigators”.
Conclusions
Existing resources for reporting health equity in observational studies aligned with our interim checklist of candidate items. We also identified additional items that will be considered in the development of a consensus- and evidence-based guideline for reporting health equity in observational studies
Improving social justice in observational studies: protocol for the development of a global and indigenous STROBE-Equity reporting guideline
- Author
- Akl Elie A.
- Antequera Alba
- Avey Marc T.
- Bhuta Zulfiqar A.
- Chamberlain Catherine
- Craig Peter
- Cuervo Luis Gabriel
- Dewidar Omar
- Dicko Alassane
- Ellingwood Holly
- Feng Cindy
- Francis Damian
- Funnell Sarah
- Ghogomu Elizabeth
- Greer-Smith Regina
- Hardy Billie-Jo
- Harwood Matire
- Hatcher-Roberts Janet
- Horsley Tanya
- Juando-Prats Clara
- Jull Janet
- Kasonde Mwenya
- Kennedy Michelle
- Kredo Tamara
- Krentel Alison
- Kristjansson Elizabeth
- Langer Laurenz
- Lawson Daeria O.
- Lesperance Miranda
- Little Julian
- Loder Elizabeth
- Magwood Olivia
- Mahande Michael Johnson
- Mbuagbaw Lawrence
- Melendez-Torres G.J.
- Moore Ainsley
- Nguilefem Nkangu Mirian
- Niba Loveline Lum
- Nicholls Stuart G.
- Obuku Ekwaro
- Okwen Patrick
- Pantoja Tomas
- Petkovic Jennifer
- Petticrew Mark
- Pottie Kevin
- Rader Tamara
- Ramke Jacqueline
- Riddle Alison
- Rizvi Anita
- Shamseer Larissa
- Sharp Melissa
- Shea Bev
- Tanuseputro Peter
- Tufte Janice
- Tugwell Peter
- Von Elm Erik
- Waddington Hugh Sharma
- Wang Harry
- Wang Xiaoqin
- Weeks Laura
- Welch Vivian
- Wells George
- White Howard
- Wiysonge Charles S.
- Wolfenden Luke
- Young Taryn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2023
- Field of study
No abstract available
Petition Alleging Violations of the Human Rights of John Melvin Alexander et al. by the United States of America
- Author
- Alice Higgs Lollis
- Alice Presley
- Allen Matthew White
- Almadge J Newkirk
- Archie Jackson Franklin
- Artie Lacy Johnson
- Beatrice Campbell-Webster
- Bertha Guyton
- Bertram C Williams
- Bessie Mae Austin Vester
- Beulah Loree Keenan Smith
- Blanche Chatman Cole
- C H R Inter-Am
- C H R Mary
- Cambridge Hauser Hall
- Carol
- Carrie Humphrey Cudjoe
- Cecil White
- Charles Hughes
- Charles J Ogletree
- Charles Ogletree
- Clarence Bruner
- Cora Hawkins Renfro
- D C Washington
- Delois Vaden Ramsey
- Dolly Mae Doufitt
- Dorothy Booker Boulding
- Dorothy Wilson Strickland
- Dr Hobart Jarrett
- Edward
- Edward L Givens
- Effie Lee Spears Todd
- Eldoris Mae Ector
- Ernestine Gibbs
- Essie Lee Johnson Beck
- Eunice
- Frances Blackwell
- Franklin Hazel
- Freddie Scott Payne
- Gay J Mcdougall
- Gay J. McDougall
- Genevieve Elizabeth Tillman Jackson
- Gerline Helen
- Granville Otis
- Hal "
- Harold Gibbs
- Hazel Dolores Smith Jones
- Ida Burns Patterson
- Ishmael S Moran
- J B Bates
- James D Bell
- James Dale Carter
- James Durant
- James L Steward
- Jeanette Mcneal Bradshaw
- Jewel Smitherman Rogers
- Jimmie Lilly Franklin
- Joan Alexander Powdrill
- Joan Hill Gambrel
- Joe R Burns
- John Hope Franklin
- John Melvin Alexander
- Johnnie L Grayson
- Joyce Walker
- Juanita Delores Burnett Arnold
- Juanita Maxine Scott Parry
- Juanita Smith Booker
- Juanita Williams Blakely
- Julia Bonton Jones
- Julius Warren Scott
- Kathryn Mae Taylor Tolin
- Katie Mae Johnson Livingston
- Kinney Booker
- Laverne Cooksey Davis
- Leanna Johnson Lewis
- Lee Ella Strozier
- Leroy Leon Hatcher
- Lewis Clotie
- Lois White Taylor
- Lola Sneed Snowden
- Louie Barton Williams
- Lucille B Buchanan Figures
- Lula Belle Lacy Bullock
- Madeleine Haynes
- Marie Whitehorn
- Mary
- Mary Leon Brown Watson
- Massachusetts Ave
- Melvin C Todd
- Mildred
- Mildred Johnson Hall
- Mildred Lucas Clark
- Mildred Mitchell Christopher
- Muriel Mignon Lilly Cabell
- Myrtle Napier Oliver
- Myrtle Wells Hurd
- Naomi Hooker Chamberlain
- Naomi Siplin
- Nell Hamilton Hampton
- Olivia J Dr
- Oscar Douglas Washington
- Percy Jones
- Phines Bell
- Queen Esther Love Walker
- Roanna Henry Mcclure
- Robert Holloway
- Rosa L Green
- Rosella Carter
- Ruth Dean Nash
- Samuel Cassius
- Samuel L Hooker
- Samuel Walker
- Sandy Clark
- Sarah Tatum
- Simeon L Neal
- Simon R Richardson
- Teresa Earlee Bridges Dysart
- Thelma Thurman Knight
- Theressa Cornella Mcneal Gilliam
- Troy Sidney Walker
- Tuleta S Duncan
- Veneice Dunn
- Vera Ingram
- Vi
- Wess Young
- William A Scott
- William Harold Wood
- Williams Golden
- Willie Bell White
- Willie Mae
- Willie Musgrove Means
- Wilma Mitchell Johnson
- Wordie "
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2005
- Field of study
Deep Underground Neutrino Experiment (DUNE) Near Detector Conceptual Design Report
- Author
- Abed Abud Adam
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adamov Giorge
- Adams David
- Adinolfi Marco
- Aduszkiewicz Antoni
- Ahmad Zubayer
- Ahmed Jhanzeb
- Alion Tyler
- Alonso Monsalve Saul
- Alrashed Munerah
- Alt Christoph
- Alton Andrew
- Amedo Pablo
- Anderson John
- Andreopoulos Costas
- Andrews Michael P
- Andrianala Fenompanirina
- Andringa Sofia
- Anfimov Nikolay
- Ankowski Artur
- Antonova Maria
- Antusch Stefan
- Aranda-Fernandez Alfredo
- Ariga Akitaka
- Arnold Lukas
- Arroyave Manuel
- Asaadi Jonathan
- Aurisano Adam
- Aushev Vladimir
- Autiero Dario
- Ayala-Torres Marco Alberto
- Azfar Farrukh
- Back A.
- Back Henning
- Back John
- Backhouse Chris
- Baesso Paolo
- Bagaturia Iuri
- Bagby Linda
- Balasubramanian Supraja
- Baldi Pierre
- Baller Bruce
- Bambah Bindu
- Barao Fernando
- Barenboim Gabriela
- Barker Gary J
- Barkhouse Wayne
- Barnes Christopher
- Barr Giles
- Barranco Monarca Juan
- Barros Nuno
- Barrow Joshua
- Basharina-Freshville Anastasia
- Bashyal Amit
- Basque Vincent
- Batista das Chagas Ewerton
- Battat J.B. R.
- Battisti Federico
- Bay Fatih
- Bazo Alba José Luis
- Beacom John
- Bechetoille Edouard
- Behera Biswaranjan
- Belchior E.
- Bellantoni Leo
- Bellettini Giorgio
- Bellini Vincenzo
- Beltramello Olga
- Belver Daniel
- Benekos Nektarios
- Bento Neves Francisco
- Berkman Sophie
- Bernardini Paolo
- Berner Roman
- Berns Hans-Gerd
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- de Almeida Rogerio
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- Dwyer Daniel A
- Dyshkant Alexandre S
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- Steiner Herbert M
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- Thea Alessandro
- Thompson Joshua
- Thorn Craig
- Timm Steven C
- Todd Jacob
- Tonazzo Alessandra
- Torbunov Dmitri
- Torti Marta
- Tortola Mariam
- Tortorici Francesco
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- Totani Dante
- Toups Matthew
- Touramanis Christos
- Travaglini R.
- Trevor Jason
- Trilov Stoyan
- Trzaska Wladyslaw
- Tsai Yun-Tse
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- Tufanli Serhan
- Tull Craig
- Tyley E.
- Tzanov Martin
- Uchida Melissa
- Urheim Jon
- Usher Tracy
- Uzunyan Sergey
- Vagins Mark
- Vahle Patricia
- Valdiviesso Gustavo
- Valencia Edgar
- Valerio P.
- Vallari Zoya
- Valle J.W. F.
- Vallecorsa Sofia
- Van Berg Rick
- Van de Water Richard
- Varanini Filippo
- Vargas Danaisis
- Varner Gary
- Vasel Justin
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- Vaughan Noah
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- Vignoli Chiara
- Vilela Cristovao
- Viren Brett
- Vrba Tomas
- Wachala Tomasz
- Waldron Abigail
- Wallbank Michael
- Wang Hanguo
- Wang Jingbo
- Wang L.
- Wang M.H. L.S.
- Wang Yi
- Wang Yue
- Warburton Karl
- Warner David
- Wascko Morgan
- Waters David
- Watson Alan
- Weatherly Pierce
- Weber Alfons
- Weber Michele
- Wei Hanyu
- Weinstein Amanda
- Wenman Dan
- Wetstein Matthew
- White Andy
- Whitehead Leigh
- Whittington Denver
- Wilking Michael
- Wilkinson Callum
- Williams Zachary
- Wilson Fergus
- Wilson Robert
- Wolcott Jeremy
- Wongjirad Taritree
- Wood Anthony
- Wood Kevin
- Worcester Elizabeth
- Worcester Matthew
- Wret Clarence
- Wu Wanwei
- Wu Wenjie
- Xiao Yiwen
- Yandel Erin
- Yang Guang
- Yang Kang
- Yang Shaokai
- Yang Tingjun
- Yankelevich Alejandro
- Yershov Nikolai
- Yonehara Katsuya
- Young Tim
- Yu Bo
- Yu Haiwang
- Yu Jae
- Yuan Wenlong
- Zaki Rowan
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zazueta Luis
- Zeit Grace
- Zeller G.P.
- Zeller Geralyn
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhao Manhong
- Zhivun Elena
- Zhu Guanying
- Zilberman Perri
- Zimmerman Eric
- Zito Marco
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- 'MDPI AG'
- Publication date
- 01/01/2021
- Field of study
International audienceThe Deep Underground Neutrino Experiment (DUNE) is an international, world-class experiment aimed at exploring fundamental questions about the universe that are at the forefront of astrophysics and particle physics research. DUNE will study questions pertaining to the preponderance of matter over antimatter in the early universe, the dynamics of supernovae, the subtleties of neutrino interaction physics, and a number of beyond the Standard Model topics accessible in a powerful neutrino beam. A critical component of the DUNE physics program involves the study of changes in a powerful beam of neutrinos, i.e., neutrino oscillations, as the neutrinos propagate a long distance. The experiment consists of a near detector, sited close to the source of the beam, and a far detector, sited along the beam at a large distance. This document, the DUNE Near Detector Conceptual Design Report (CDR), describes the design of the DUNE near detector and the science program that drives the design and technology choices. The goals and requirements underlying the design, along with projected performance are given. It serves as a starting point for a more detailed design that will be described in future documents
Reconstruction of interactions in the ProtoDUNE-SP detector with Pandora
- Author
- Abed Abud Adam
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adames Marcio
- Adamov George
- Adamowski Mark
- Adams David
- Adinolfi Marco
- Adriano Cris
- Aduszkiewicz Antoni
- Aguilar Jessica
- Ahmad Zubayer
- Ahmed Jhanzeb
- Aimard Benjamin
- Akbar Faiza
- Ali-Mohammadzadeh Behnam
- Allison Kyle
- Alonso Monsalve Saul
- Alrashed Munera
- Alt Christoph
- Alton Andrew
- Alvarez Rodrigo
- Amedo Pablo
- Anderson John
- Andreopoulos Costas
- Andreotti Mirco
- Andrews Michael P.
- Andrianala Fenompanirina
- Andringa Sofia
- Anfimov Nikolay
- Ankowski Artur
- Antoniassi Marcelo
- Antonova Maria
- Antoshkin Alexander
- Antusch Stefan
- Aranda-Fernandez Alfredo
- Arellano Luciano
- Arnold Lukas
- Arroyave Manuel
- Asaadi Jonathan
- Asquith Lily
- Aurisano Adam
- Aushev Vladimir
- Autiero Dario
- Ayala Lara Victor
- Ayala-Torres Marco Alberto
- Ayalatorres M.
- Azfar Farrukh
- Back Ashley
- Back Henning
- Back John
- Backhouse Chris
- Bagaturia Iuri
- Bagby Linda
- Balashov Nikita
- Balasubramanian Supraja
- Baldi Pierre
- Baller Bruce
- Bambah Bindu
- Barao Fernando
- Barenboim Gabriela
- Barker Gary J.
- Barkhouse Wayne
- Barnes Christopher
- Barr Giles
- Barranco Monarca Juan
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- Barrow Joshua
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- Bashyal Amit
- Basque Vincent
- Batchelor Charlie
- Battat James
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- Bay Fatih
- Bazetto Maria Cecilia
- Bazo Alba José Luis
- Bazo J.L.
- Beacom John
- Bechetoille Edouard
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- Belchior Batista das Chagas Ewerton
- Bellantoni Leo
- Bellettini Giorgio
- Bellini Vincenzo
- Beltramello Olga
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- Benitez Montiel Carlos
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- Berger Joshua
- Berkman Sophie
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- Berner Roman
- Bersani Andrea
- Bertolucci Sergio
- Betancourt Minerba
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- Bezerra Anibal
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- Bhardwaj Akhil
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- Biery Kurt
- Bilki Burak
- Bishai Mary
- Bitadze Alexander
- Blake Andrew
- Blaszczyk Flor de Maria
- Blazey Gerald C.
- Blucher Edward
- Boissevain Jan
- Bolognesi Sara
- Bolton Timothy
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- Boran Fatma
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- Bromberg Carl
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- da Motta Helio
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- de Bonis Isabelle
- de Gouvea Andre
- de Holanda Pedro
- de Icaza Astiz Iker
- de Jong Paul
- de Leo Veronica
- de Lurgio Patrick
- de Mello Neto Joao
- de Roeck Albert
- de Romeri Valentina
- de Souza Greg
- De I.
- De Kaushik
- De P.
- De P.C.
- De Shruti
- De V.
- Debbins Paul
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- Deisting Alexander
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- Di Domenico Antonio
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- Di Noto Lea
- Di A.
- Dias Marco
- Diaz Jorge S.
- Ding Pengfei
- Dirkx Glenn
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- Diurba Richard
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- Doering Dionisio
- Dolan Stephen
- Dolek Furkan
- Dolinski Michelle J.
- Domine Laura
- Donon Yann
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- Dragone Angelo
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- Duarte Laura Cristina
- Duchesneau Dominique
- Duffy Kirsty
- Dunne Patrick
- Dutta Bhaskar
- Duyang Hongyue
- Dvornikov Olexiy
- Dwyer Daniel A.
- Dyshkant Alexandre S.
- Díaz Felix
- Eads Michael
- Earle Antony
- Edmunds Daniel
- Eisch Jonathan
- Emberger Lorenz
- Emery Sandrine
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- Ereditato Antonio
- Erjavec Tyler
- Escobar Carlos O.
- Escudero Sanchez Lorena
- Eurin Guillaume
- Evans Justin
- Ewart Erin
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- Fahey Kevin
- Fajardo L.S. Gomez
- Falcone Andrea
- Fani Mattia
- Farnese Christian
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- Fedoseev Dmitry
- Felix Julian
- Feng Yue
- Fernandez Menendez Pablo
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- Ferraro Federico
- Fields Laura
- Filip Peter
- Filthaut Frank
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- Fiorillo Giuliana
- Fiorini Massimiliano
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- Flanagan Will
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- Fogarty Sam
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- Freeman John
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- Fried Jack
- Friedland Alex
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- Furic Ivan
- Furman Krzysztof
- Furmanski Andrew
- Gabrielli Alessandro
- Gago A.M.
- Gallagher Hugh
- Gallas Alexandre
- Gallego-Ros Ana
- Gallegoros A.
- Gallice Niccolo
- Galymov Vyacheslav
- Gamberini Enrico
- Gamble Trevor
- Ganacim Francisco
- Gandhi Raj
- Ganguly Sudeshna
- Gao Fan
- Gao Shanshan
- Garcia-Gamez Diego
- García- M.A.
- García-Peris Miguel
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- Gastler Dan
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- Ge Guanqun
- Geffroy Nicolas
- Gelli Bruno
- Gendotti Adamo
- Gent Stephen
- Ghorbani-Moghaddam Zahra
- Giammaria Paola
- Giammaria Tommaso
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- Gibin Daniele
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- Girerd Claude
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- Gollapinni Sowjanya
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- Gomes Ricardo
- Gomez Bermeo Laura Vanessa
- Gomez L.
- Gonnella Francesco
- Gonzalez-Diaz Diego
- Gonzalez-Lopez Manuel
- González Caamaño David
- González D.
- Goodman Maury
- Goodwin Owen
- Goswami Srubabati
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- Green Patrick
- Green Steven
- Greenberg Stephen
- Greenler Leland
- Greer Joel
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- Groh Micah
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- Gu Wenqiang
- Guardincerri Elena
- Guarino Victor
- Guarise Marco
- Guenette Roxanne
- Guerard Eric
- Guerzoni Marco
- Guffanti Daniele
- Guglielmi Alberto
- Guo Bing
- Gupta Aseem
- Gupta Vikas
- Guthikonda K.K.
- Guzowski Pawel
- Guzzo Marcelo
- Gwon Sunwoo
- Ha Chang Hyon
- Haaf Kevin
- Habig Alec
- Hadavand Haleh
- Haenni Roger
- Hahn Alan
- Haiston James
- Hamacher-Baumann Philip
- Hamacherbaumann P.
- Hamernik Thomas
- Hamilton Philip
- Han Jiyeon
- Harris Deborah
- Hartnell Jeffrey
- Hartnett Trevor
- Harton John
- Hasegawa Takyua
- Hasnip Ciaran
- Hatcher Robert
- Hatfield Kaleb
- Hatzikoutelis Athanasios
- Hayes Christopher
- Hayrapetyan Karen
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- Hazen Eric
- He Muyuan
- Heavey Anne
- Heeger Karsten
- Heise Jaret
- Henry Sarah
- Hernandez Morquecho Miguel Angel
- Herner Kenneth
- Hewes Jeremy
- Hilgenberg Christopher
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- Hillier Stephen
- Himmel Alexander
- Hinkle Elise
- Hirsch Luciana
- Ho Johnny
- Hoff James
- Holin Anna
- Hoppe Eric
- Horton-Smith Glenn
- Hostert Matheus
- Hourlier Adrien
- Howard Bruce
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- Hronek Maxine
- Huang Junying
- Hulcher Zachary
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- Ilic Nikolina
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- Isenhower Larry
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- Jackson Christopher
- Jain Vivek
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- Ji Xiangpan
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- Jones Benjamin
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- Karolak Mark
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- Kasai Seiji
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- Kashur Lane
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- Kearns Edward
- Keener Paul
- Kelly Kevin
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- Kemularia Otari
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- Khabibullin Marat
- Khotjantsev Alexei
- Khvedelidze Arsen
- Kim Doojin
- King Bonnie
- Kirby Brian
- Kirby Mike
- Klein Joshua
- Klustova Anezka
- Kobilarcik Thomas
- Koehler Kevin
- Koerner Lisa
- Koh D.H.
- Kohn Sam
- Koller Patrick
- Kolupaeva Liudmila
- Korablev Denis
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- Kosc Thomas
- Kose Umut
- Kostelecky V. Alan
- Kothekar Kunal
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- Kubota Shion
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- Kuhlmann Stephen
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- Laurenti Giuliano
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- Leardini Sara
- Learned John
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- Lehnert Ralf
- Leigui de Oliveira M.A.
- Leitner Matthaeus
- Lepin Luis
- Li Shirley W.
- Li Yichen
- Liao Heng-Ye
- Lin Cheng-Ju Stephen
- Lin Qing
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- Lineros Roberto
- Ling Jiajie
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- Loew Timothy
- Lokajicek Milos
- Lomidze Irakli
- Long Ken
- Lord Tom
- Losecco John M.
- Louis William
- Lu Xianguo
- Luk Kam-Biu
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- Madigan Peter
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- Martinez Norman
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- Mason Katie
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- Mcnab Andrew
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- Mendez Hector
- Mendez Patricia
- Menegolli A.
- Meng Guang
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- Mousseau Joel
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- Mu Wei
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- Nagu Srishti
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- Onel Yasar
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- Ott Jordan
- Pagani Luca
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- Psihas Fernanda
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- Qian Xin
- Raaf Jennifer L.
- Radeka Veljko
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- Ratoff Peter
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- Shaevitz Michael H.
- Shafaq Sheeba
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- Siyeon Kim
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- Snider E.L.
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- Solano Salinas Carlos
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- Steklain Lisbôa André
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- Suárez Sunción Juan Martín
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- Tata Neeraj
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- Tishchenko Vladimir
- Tomassetti Luca
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- Tufanli Serhan
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- Tyler Jennifer
- Tyley E.
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- Uboldi Lorenzo
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- Usher Tracy
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- Vagins Mark
- Vahle Patricia
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- van Berg Rick
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- Vasseur Georges
- Vaughan Noah
- Vaziri Kamran
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- Verdugo Antonio
- Vergani Stefano
- Vermeulen Milo
- Verzocchi Marco
- Vicenzi Matteo
- Vieira de Souza Henrique
- Vignoli Chiara
- Vilela Cristovao
- Viren Brett
- Vrba Tomas
- Wachala Tomasz
- Waldron Abigail
- Wallbank Michael
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- Wang Jingbo
- Wang Li
- Wang Michael
- Wang Xiaoran
- Wang Yi
- Wang Yue
- Warburton Karl
- Warner David
- Wascko Morgan
- Waters David
- Watson Alan
- Wawrowska Klaudia
- Weatherly Pierce
- Weber Alfons
- Weber Michele
- Wei Hanyu
- Weinstein Amanda
- Wenman Dan
- Wetstein Matthew
- White Andy
- Whitehead Leigh
- Whittington Denver
- Wilking Michael
- Wilkinson Alexander
- Wilkinson Callum
- Williams Zachary
- Wilson Fergus
- Wilson Robert
- Wisniewski William
- Wolcott Jeremy
- Wongjirad Taritree
- Wood Anthony
- Wood Kevin
- Worcester Elizabeth
- Worcester Matthew
- Wresilo Karolina
- Wret Clarence
- Wu Wanwei
- Wu Wenjie
- Xiao Yiwen
- Yaeggy Barbara
- Yandel Erin
- Yang Guang
- Yang Kang
- Yang Tingjun
- Yankelevich Alejandro
- Yershov Nikolai
- Yonehara Katsuya
- Yoon Young Soo
- Young Tim
- Yu Bo
- Yu Haiwang
- Yu Hongzhao
- Yu Jae
- Yu Yiding
- Yuan Wenlong
- Zaki Rowan
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zazueta Luis
- Zeller Geralyn
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhang Shuaixiang
- Zhang Yuze
- Zhao Manhong
- Zhivun Elena
- Zhu Guanying
- Zimmerman Eric
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- HAL CCSD
- Publication date
- 18/07/2022
- Field of study
International audienceThe Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandora is the primary event reconstruction software used at ProtoDUNE-SP, a prototype for the Deep Underground Neutrino Experiment far detector. ProtoDUNE-SP, located at CERN, is exposed to a charged-particle test beam. This paper gives an overview of the Pandora reconstruction algorithms and how they have been tailored for use at ProtoDUNE-SP. In complex events with numerous cosmic-ray and beam background particles, the simulated reconstruction and identification efficiency for triggered test-beam particles is above 80% for the majority of particle type and beam momentum combinations. Specifically, simulated 1 GeV/c charged pions and protons are correctly reconstructed and identified with efficiencies of 86.1±0.6% and 84.1±0.6%, respectively. The efficiencies measured for test-beam data are shown to be within 5% of those predicted by the simulation
Separation of track- and shower-like energy deposits in ProtoDUNE-SP using a convolutional neural network
- Author
- Abed Abud Adam
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adames Marcio
- Adamov George
- Adamowski Mark
- Adams David
- Adinolfi Marco
- Aduszkiewicz Antoni
- Aguilar Jessica
- Ahmad Zubayer
- Ahmed Jhanzeb
- Aimard Benjamin
- Ali-Mohammadzadeh Behnam
- Alion Tyler
- Allison Kyle
- Alonso Monsalve Saul
- Alrashed Munera
- Alt Christoph
- Alton Andrew
- Alvarez Rodrigo
- Amedo Pablo
- Anderson John
- Andreopoulos Costas
- Andreotti Mirco
- Andrews Michael P.
- Andrianala Fenompanirina
- Andringa Sofia
- Anfimov Nikolay
- Ankowski Artur
- Antoniassi Marcelo
- Antonova Maria
- Antoshkin Alexander
- Antusch Stefan
- Aranda-Fernandez Alfredo
- Arellano Luciano
- Arnold Lukas
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- Warburton Karl
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- Weber Michele
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- Worcester Matthew
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- Wu Wenjie
- Xiao Yiwen
- Xie Fang
- Yaeggy Barbara
- Yandel Erin
- Yang Guang
- Yang Kang
- Yang Tingjun
- Yankelevich Alejandro
- Yershov Nikolai
- Yonehara Katsuya
- Yoon Young Soo
- Young Tim
- Yu Bo
- Yu Haiwang
- Yu Hongzhao
- Yu Jae
- Yu Yiding
- Yuan Wenlong
- Zaki Rowan
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zazueta Luis
- Zeller Geralyn
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhang Shuaixiang
- Zhang Yuze
- Zhao Manhong
- Zhivun Elena
- Zhu Guanying
- Zimmerman Eric
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
International audienceLiquid argon time projection chamber detector technology provides high spatial and calorimetric resolutions on the charged particles traversing liquid argon. As a result, the technology has been used in a number of recent neutrino experiments, and is the technology of choice for the Deep Underground Neutrino Experiment (DUNE). In order to perform high precision measurements of neutrinos in the detector, final state particles need to be effectively identified, and their energy accurately reconstructed. This article proposes an algorithm based on a convolutional neural network to perform the classification of energy deposits and reconstructed particles as track-like or arising from electromagnetic cascades. Results from testing the algorithm on experimental data from ProtoDUNE-SP, a prototype of the DUNE far detector, are presented. The network identifies track- and shower-like particles, as well as Michel electrons, with high efficiency. The performance of the algorithm is consistent between experimental data and simulation