FORMULASI SABUN TRANSPARAN MINYAK BUAH MERAH (Pandanus conoideus Lam.)

Red fruit oil is known to be very useful as antioxidants are beneficial for skin health, especially to prevent damage cell components that cause premature aging of the skin. Based on the study of antioxidant activity with IC50 value of 53.47 µg / mL. This study aimed to obtain a formula that possess optimal physical stability. In this study, three formulas designed by varying the precursor, namely the formula I with soap formation ingredients palm oil and olive oil, the formula II with VCO soap-forming ingredients and olive oil, and formula III with ingredients forming castor oil soaps and oils olives. Each physical stability of the formulations was evaluated by testing parameters include the foam test, hardness test, test the pH, organoleptic and sensory evaluation test on the skin. Results showed that the formula that has optimum physical stability is Formula I with component-forming material palm oil soaps and olive oil

PENGEMBANGAN FORMULASI MIKROEMULSI MINYAK SEREH (Cymbopogon nardus) MENGGUNAKAN EMULGATOR SURFAKTAN NONIONIK

Citronella oil (Cymbopogon nardus) is an essential oil which useful as an antibacterial that is usuallyprovided in the form of macroemulsion for topical use. absorption of macroemulsion through the skin relatively low, thermodynamically is not stable and can produce a separate phase in the storage period. The one of development emulsion  system  to  get  better  characteristics  is  to  form  a  microemulsion.  Microemulsion  is  an  oil  and  water dispersion stable thermodynamically stabilized by surfactants and in some cases a cosurfactant. The objective of this study was to formulatecitronella oil in the form of a stable microemulsion using nonionic surfactant. Optimization of the type and amount of emulsifier (surfactant) was required to formulate a stable microemulsion. In this study, microemulsion was evaluated during a month. Type   and concentration of surfactant, cosurfactant, Citronella oil (Cymbopogon nardus) and water was optimized. A stable citronella oil microemulsion was successfully created with composition of 15% PEG 400 as cosurfactant, 15% tween 80 as surfactant, 2-4% Citronella oil as oil phase and 10% glycerin as humectant and distilled water as aqueous phase. From the observation, microemulsion formula has   clear appearance but  physically unstable during a month storag

POTENSI BIOSELULOSA YANG DIFORTIFIKASI DENGAN ANTIMIKROBA ALAMI SEBAGAI WOUND DRESSING LUKA BAKAR

Telah dilakukan penelitian mengenai produksi bioselulosa oleh\ud Acetobacter xylinum\ud menggunakan media yang mengandung limbah cair kakao, dan difortifikasi dengan ekstrak\ud Ganoderma sebagai antibakteri untuk pemanfaatannya sebagai pembalut luka b\ud akar. Untuk itu\ud dalam penelitian tahap pertama telah dilakukan optimalisasi produksi bioselulosa oleh\ud Acetobacter xylinum\ud melalui variasi konsentrasi limbah cair buah kakao dalam media fermentasi\ud Optimalisasi ekstraksi komponen antibakteri Ganoderma mel\ud alui variasi cairan penyari, serta uji\ud aktivitas antibakteri dari bioselulosa yang difortifikasi dengan ekstrak Ganoderma terhadap\ud bakteri\ud Staphylococcus aureus\ud dan\ud Pseudomonas aeroginosa\ud .\ud Hasil penelitian dan diperoleh : a.\ud Konsentrasi limbah cair kakao\ud 7,5 % yang disarankan digunakan dalam media yang\ud mengandung MgSO\ud 4\ud 0,01\ud %, (NH\ud 4\ud )\ud 2\ud SO\ud 4\ud 0,05 %\ud dan\ud sukrosa 10 % untuk produksi bioselulosa;\ud b. analisis\ud Scanning Electron Microscopy\ud memperlihatkan struktur permukaan bioselulosa yang\ud terbentuk memiliki uk\ud uran fibril 2\ud ???\ud 50\ud ???m, dan analisis FTIR memperlihatkan karakteristik\ud pita\ud -\ud pita biosellulosa muncul pada bilangan gelombang (cm\ud -\ud 1\ud ) 3356.18, 2908.22, 1665.79 ,\ud 1161,72, 1110.88, 1069,27, dan 667,12; c. Ekstrak Ganoderma yang dijerap ke dalam\ud bioselu\ud losa memiliki aktivitas antibakter

Uji Daya Hambat Dan Analisis Klt-bioautografi Perasan Buah Sawo Manila (Achras Zapota Linn) Terhadap Bakteri Uji Salmonella Thyposa

The inhibitory effect of juice of Sawo Manilas (Achras zapota Linn) fruit on the growth of tested bacteria Salmonella thyposa Linn by using Thin Layer Chromatography (TLC) Bioautography Method had been done. The aim of this research was to test the ability of the juice as an antibacterial compound in inhibitory bacterial growth and also to know which are the chemical compound in inhibitory bacterial growth and also to know which are of the chemical compound separated by TLC still have antibacterial effect after done TLC Bioautography. The result was show that Sawo manilas fruit was potensially to inhibit the growth of Salmonella thyposa with a large diametric inhibitor zone.The result of TLC-Bioautography ware shown 2 active compound of three.Key Words: Inhibitory, Sawo Manila, TLC-Bioautography, Salmonella Thypos

FORMULASI SUSPENSI KERING KOMBINASI EKSTRAK ETANOL KUNYIT (Curcuma longa L.) DAN SERBUK DAGING BUAH PISANG KEPOK (Musa balbisiana Colla.) DENGAN VARIASI BAHAN PENSUSPENSI

Background :For long time ago various research has been done on both curcuma and banana fruit. Result showed that curcumin which contained in curcuma and cytoindosin, tannin, amylum on banana function as antipeptic ulcer. PUD (peptic ulcer disease) is remain the most common disease of gastrointestinal tract, so which influence life quality, disorder in works, and higher of medical treatment cost. Most of patient of which expect prompt effect of preparations. Based on this, suspension was made to give the prompt  effect, due to fine particles of the suspensoid which is not degradated or aggregated in time.The Aim :to obtain dry suspension  from which is pharmaceutically stable from combination of curcuma (Curcuma longa L.) aethanolic extracts and the powder of banana (Musa balbisiana Colla.) flesh using a various of suspending agent.Method : it was experimental method which was a research method in laboratory conducted by preparing some formulation designs of dry suspension fromcombination of curcuma (Curcuma longa L.) aethanolic extracts and the powder of banana (Musa balbisiana Colla.) flesh.Conclusion :the suspending agent producing the pharmaceutically stable dry suspension is magnesium aluminium silicate with 4% concentration Keyword : Curcuma, Banana Fruit, Dry Suspension, Peptic Ulcer

FORMULASI YOGHURT SEBAGAI LOSIO PEMBERSIH WAJAH DENGAN MENGGUNAKAN VARIASI EMULGATOR

Yoghurt formulation as facial cleansing lotion has been done in which the emulsifier were nonionic (tween 60 and span 60), amine soap (triethanolamin and stearic acid), and detergent (sodium lauryl sulfate) respectively. The aim was to determine the most optimum stabilty formulation. The evaluation was carried out before and after accelerated condition in 5ºC and 35ºC respectively for 10 cycles.Organoleptic, creaming volume, emulsion type, dirpersed globul, viscosity, and yield value were observed. The result of organoleptik showed that there were no change in color and smell, creaming volume and dispersed globul before and after accelerated condition. Statystic analyses foward the viscosity in formula I was apparently indifferent mean while the second and the third formula were different in viscosity. statystic analyses foward the yield value in formula I was apparently indifferent and the second  was different mean while  the third formula very different in yield value. Formula I showed the most minimum alteration in rheogram . Of it the has taken that the most stable emulsion was nonionic emulsifier (tween 60 and span 60).Key Words : Facial cleansing lotion, Yoghurt, Emulgato

Uji Aktivitas ANtioksidan Ekstrak Etil Asetat Kayu Batang Banyuru Sulawesi (Pterospermum celebicum Miq) Dengan Metode Penangkapan Radikal Bebas DPPH (2,2 Diphenyl-1-Picryl-Hydrzyl))

Telah dilakukan penelitian uji aktivitas antioksidan ekstrak etil asetat kayu batang Banyuru Sulawesi (Pterospermum celebicum mig.). Dengan metode penangkapan radikal bebas DPPH (2,2-diphenyl-1-picryl-hydrazy) dan menggunakan metode spektrofotometri UV-VIS. HAsil penelitian menunjukkan aktivitas senyawa antioksidan ekstrak dengan menggunakan metode pengikatan radikal bebas 2,2-diphenyl-1-picrylhydrazyl (DPPH) terhadap data diperoleh dengan nilai IC50 180 ppm, sehingga efektif sebagai sumber antiosidan alternati