447 research outputs found

    A note on quasi-Gorenstein rings

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    In this paper, after giving a criterion for a Noetherian local ring to be quasi-Gorenstein, we obtain some sufficient conditions for a quasi- Gorenstein ring to be Gorenstein. In the course, we provide a slight generalization of a theorem of Evans and Griffith.Comment: To appear in Arch. Mat

    TECHNICAL NOTE CHARACTERIZATION OF CONSTRAINED AGED NiTi STRIPS FOR USING IN ARTIFICIAL MUSCLE ACTUATORS

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    Abstract Marvelous bending/straightening effects of two-way shape memory alloy (TWSMA) help their employment in design and manufacturing of new medical appliances. Constrained ageing with bending load scheme can induce two-way shape memory effect (TWSME). Scanning electron microscopic (SEM) analysis, electrical resistivity measurement (ERM) and differential scanning calorimetry (DSC) are employed to determine the property change due to flat strip constrained aging. Results show that flat-annealing prior to the aging shifts NiTi transformations temperatures to higher values. Superelastic behavior of the as-received/flat-annealed/aged samples with more adequate transition temperatures due to biological tissue replacement is studied by three-point flexural tests. Results show that curing changes the transition points of the NiTi strips. These changes affect the shape memory behavior of the NiTi strips embedded within the biocompatible flexible composite segments

    The effect of irrigation intervals scheduling and nitrogen and zinc content on wheat yield and yield components in drought stress

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    In order to evaluate the effect of irrigation interval on yield and quantitative-qualitative characteristics of bread wheat, splited plot experiment in randomized block with four replications in the 2010-11 crop years was conducted in the research field of Islamic Azad University of Gonabad. A number of 7, 9 and 10 days irrigation treatments formed the main factors of test, and spraying and nonspraying of nitrogen and zinc were considered as subfactor of test. The results showed that the effect of irrigation was significant for the number of grains per spike in the level of 5% and on 1000-grain weight and fat percent at the level of 1%, and had no significant effect on grain yield, biological yield, number of spikes/sq m stem height, stem diameter and protein content. Nitrogen treatment was significant at the level of 5% on biological yield and number of spikes/sq m, but had no significant effect on grain yield, number of grains per spike, 1000-grain weight, stem height, fat and protein percent, and stem diameter. Treatment with zinc was statistically significant in probability level of 1% only on percentage of fat and had no significant effect on grain yield, biological yield, grain numbers per spike, weight of 1000 seeds, spikes/sq m, stem height, protein percent and stem diameter. Seven days irrigation with of nitrogen allocated for highest seed yield (265.38 g/m²/sq m) and biological yield (659.33 g/m²/sq m). Means comparison showed the highest 1000-grain weight was obtained from 7 days irrigation (47.10 g) and the lowest from 13 days irrigation (40.44 g). According to the experiment results, 7 days irrigation was recognized as the best irrigation to achieve maximum economic performance and 13 days irrigation were determined as most appropriate irrigation for maximum performance for the region due to lack of water and weather conditions of Gonabad, spraying zinc and nitrogen to improve production was proposed depending on different irrigation and the purpose of production

    Anti-Ulcerative Potential of Punica granatum L (Lythraceae) Hydroalcohol Fruit Peel Extract

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    Purpose: To evaluate the antiulcer activities of the methanol extract of pomegranate (Punica granatum L) fruit peel using 80 % ethanol-induced gastric ulcer model in rats.Methods: Male Wistar rats, 175 - 220 g, were fasted for 48 h, but had free access to water. They were randomly divided into nine experimental groups. Ulcer was induced in the rats with 80 % ethanol. The control group animals received the same treatment as those in the test groups except that the extract treatment was replaced by administration of appropriate volume of the dosing vehicle. Histaminereceptor type-2 (H2) blocker, cimetidine (100 mg/kg, i.p.) was used as the reference drug. Oral pretreatment with three different extract doses (25, 50 and 100 mg/kg) was for 15 days, thereafter, ulcer index (UI) and inhibition were calculated.Results: The extract, at 50 mg/kg, of black fruit peel extract produced significant (p < 0.05) protective effect in rats with a preventive index of 65.87 %. Other doses were significantly protective against ethanol-induced gastric ulcer in the rats. On the other hand, north white peel was not effective (50 mg/kg) showed an ulcer index of 49.52 ± 1.99. Histopathological examination of the stomach of the ulcerated animals treated with white peel (50 mg/kg) showed severe erosion of gastric mucosa, submucosal edema and neutrophil infiltration.Conclusion: The study shows indicates the antiulcer properties of the methanol extracts of north white peel, sour summer and black peel (25, 50, 100 mg/kg) of pomegranate. Their antiulcer activity is exerted, possibly, via its high antioxidant activity.Keywords: Anti-inflammatory, Pomegranate, Punica granatum, Peel extrac

    Assessing field‐scale risks of foliar insecticide applications to monarch butterfly (Danaus plexippus) larvae

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    Establishment and maintenance of milkweed plants (Asclepias spp.) in agricultural landscapes of the north central United States are needed to reverse the decline of North America\u27s eastern monarch butterfly (Danaus plexippus) population. Because of a lack of toxicity data, it is unclear how insecticide use may reduce monarch productivity when milkweed habitat is placed near maize and soybean fields. To assess the potential effects of foliar insecticides, acute cuticular and dietary toxicity of 5 representative active ingredients were determined: beta‐cyfluthrin (pyrethroid), chlorantraniliprole (anthranilic diamide), chlorpyrifos (organophosphate), and imidacloprid and thiamethoxam (neonicotinoids). Cuticular median lethal dose values for first instars ranged from 9.2 × 10–3 to 79 μg/g larvae for beta‐cyfluthrin and chlorpyrifos, respectively. Dietary median lethal concentration values for second instars ranged from 8.3 × 10–3 to 8.4 μg/g milkweed leaf for chlorantraniliprole and chlorpyrifos, respectively. To estimate larval mortality rates downwind from treated fields, modeled insecticide exposures to larvae and milkweed leaves were compared to dose–response curves obtained from bioassays with first‐, second‐, third‐, and fifth‐instar larvae. For aerial applications to manage soybean aphids, mortality rates at 60 m downwind were highest for beta‐cyfluthrin and chlorantraniliprole following cuticular and dietary exposure, respectively, and lowest for thiamethoxam. To estimate landscape‐scale risks, field‐scale mortality rates must be considered in the context of spatial and temporal patterns of insecticide use

    A rapid co-culture stamping device for studying intercellular communication.

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    Regulation of tissue development and repair depends on communication between neighbouring cells. Recent advances in cell micro-contact printing and microfluidics have facilitated the in-vitro study of homotypic and heterotypic cell-cell interaction. Nonetheless, these techniques are still complicated to perform and as a result, are seldom used by biologists. We report here development of a temporarily sealed microfluidic stamping device which utilizes a novel valve design for patterning two adherent cell lines with well-defined interlacing configurations to study cell-cell interactions. We demonstrate post-stamping cell viability of >95%, the stamping of multiple adherent cell types, and the ability to control the seeded cell density. We also show viability, proliferation and migration of cultured cells, enabling analysis of co-culture boundary conditions on cell fate. We also developed an in-vitro model of endothelial and cardiac stem cell interactions, which are thought to regulate coronary repair after myocardial injury. The stamp is fabricated using microfabrication techniques, is operated with a lab pipettor and uses very low reagent volumes of 20 μl with cell injection efficiency of >70%. This easy-to-use device provides a general strategy for micro-patterning of multiple cell types and will be important for studying cell-cell interactions in a multitude of applications

    A novel pathogenic variant of SRD5A2 in an Iranian psuedohermaphrodite male

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    Deficiency of the 5-alpha-reductase may have an important role in 46,XY DSD in some cohorts. The prenatal ultrasonography and karyotyping can trigger the attention toward the presence of a DSD in fetus. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Lt

    Occupational cognitive failure and its relationship with unsafe behaviors and accidents

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    Objectives. The aim of this study was to assess the relationship between occupational cognitive failures (OCFs) and unsafe behaviors, accidents and driving offences among municipal bus drivers in Tehran, Iran. Methods. Systematic random sampling was used to select 190 drivers from 3 transport and traffic Tehran districts. Data were collected with the occupational cognitive failure questionnaire (OCFQ), the driver behavior questionnaire and a data collection form. Results. The mean (SD) numbers of driving-related offences and road traffic accidents were 1.5 (2.6) and 0.37 (1.0), respectively. The mean (SD) numbers of deliberate driving violations, unintended violations, driving slips and mistakes were 6.97 (5.5), 1.61 (1.5), 13.6 (9.0) and 4.53 (3.28), respectively. The mean (SD) number of the OCFs was 28.9 (20.5). A significant correlation was found between occupational cognitive error and unsafe driving behavior subscales. The stepwise logistic regression results showed that, while controlling the effects of confounding factors, the OCF predicts 6, 9, 15 and 9 of deliberate violations, unintended violations, driving slips and driving mistakes, respectively. Conclusion. The results of this study show that the score of the OCFQ is a predictor of unsafe driving behaviors and its subscales

    Sepsis recognition tools in acute ambulatory care::associations with process of care and clinical outcomes in a service evaluation of an Emergency Multidisciplinary Unit in Oxfordshire

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    To assess the performance of currently available sepsis recognition tools in patients referred to a community-based acute ambulatory care unit.Service evaluation of consecutive patients over a 4-month period.Community-based acute ambulatory care unit.Observations, blood results and outcome data were analysed from patients with a suspected infection. Clinical features at first assessment were used to populate sepsis recognition tools including: systemic inflammatory response syndrome (SIRS) criteria, National Early Warning Score (NEWS), quick Sequential Organ Failure Assessment (qSOFA) and National Institute for Health and Care Excellence (NICE) criteria. Scores were assessed against the clinical need for escalated care (use of intravenous antibiotics, fluids, ongoing ambulatory care or hospital treatment) and poor clinical outcome (all-cause mortality and readmission at 30 days after index assessment).Of 533 patients (median age 81 years), 316 had suspected infection with 120 patients requiring care escalated beyond simple community care. SIRS had the highest positive predictive value (50.9%, 95% CI 41.6% to 60.3%) and negative predictive value (68.9%, 95% CI 62.6% to 75.3%) for the need for escalated care. Both NEWS and SIRS were better at predicting the need for escalated care than qSOFA and NICE criteria in patients with suspected infection (all P<0.001). While new-onset confusion predicted the need for escalated care for infection in patients ≥85 years old (n=114), 23.7% of patients ≥85 years had new-onset confusion without evidence for infection.Acute ambulatory care clinicians should use caution in applying the new NICE endorsed criteria for determining the need for intravenous therapy and hospital-based location of care. NICE criteria have poorer performance when compared against NEWS and SIRS and new-onset confusion was prevalent in patients aged ≥85 years without infection

    The Expression of Interleukins 10 and Leptin Receptor in Peripheral Mononuclear Cells from Patients with Metabolic Syndrome

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    ABSTRACT Metabolic syndrome (MetS) is a common disease and a serious public health problem in developed countries
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