4,783 research outputs found

    Exact Keldysh theory of strong-field ionization: residue method vs saddle-point approximation

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    In recent articles [Mishima et al., Phys. Rev. A, 66, 033401(2002); Chao, Phys. Rev. A, 72, 053414 (2005)] it was proposed to use the residue theorem for the exact calculation of the transition amplitude describing strong-field ionization of atomic systems within Keldysh theory. This should avoid the necessity to apply the method of steepest descent (saddle-point approximation). Comparing the results of both approaches for atomic hydrogen a difference by a factor of 2 was found for the 1s, and an even more drastic deviation for the 2s state. Thus it was concluded that the use of the saddle-point approximation is problematic. In this work the deviations are explained and it is shown that the previous conclusion is based on an unjustified neglect of an important contribution occurring in the application of the residue theorem. Furthermore, the applicability of the method of steepest descent for the ionization of Rydberg states is discussed and an improvement of the standard result is suggested that successfully removes the otherwise drastic failure for large principal quantum numbers.Comment: 7 pages, 3 figures, 1 tabl

    Should the advanced measurement approach be replaced with the standardized measurement approach for operational risk?

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    Recently, Basel Committee for Banking Supervision proposed to replace all approaches, including Advanced Measurement Approach (AMA), for operational risk capital with a simple formula referred to as the Standardised Measurement Approach (SMA). This paper discusses and studies the weaknesses and pitfalls of SMA such as instability, risk insensitivity, super-additivity and the implicit relationship between SMA capital model and systemic risk in the banking sector. We also discuss the issues with closely related operational risk Capital-at-Risk (OpCar) Basel Committee proposed model which is the precursor to the SMA. In conclusion, we advocate to maintain the AMA internal model framework and suggest as an alternative a number of standardization recommendations that could be considered to unify internal modelling of operational risk. The findings and views presented in this paper have been discussed with and supported by many OpRisk practitioners and academics in Australia, Europe, UK and USA, and recently at OpRisk Europe 2016 conference in London

    Reed-Muller codes for random erasures and errors

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    This paper studies the parameters for which Reed-Muller (RM) codes over GF(2)GF(2) can correct random erasures and random errors with high probability, and in particular when can they achieve capacity for these two classical channels. Necessarily, the paper also studies properties of evaluations of multi-variate GF(2)GF(2) polynomials on random sets of inputs. For erasures, we prove that RM codes achieve capacity both for very high rate and very low rate regimes. For errors, we prove that RM codes achieve capacity for very low rate regimes, and for very high rates, we show that they can uniquely decode at about square root of the number of errors at capacity. The proofs of these four results are based on different techniques, which we find interesting in their own right. In particular, we study the following questions about E(m,r)E(m,r), the matrix whose rows are truth tables of all monomials of degree r\leq r in mm variables. What is the most (resp. least) number of random columns in E(m,r)E(m,r) that define a submatrix having full column rank (resp. full row rank) with high probability? We obtain tight bounds for very small (resp. very large) degrees rr, which we use to show that RM codes achieve capacity for erasures in these regimes. Our decoding from random errors follows from the following novel reduction. For every linear code CC of sufficiently high rate we construct a new code CC', also of very high rate, such that for every subset SS of coordinates, if CC can recover from erasures in SS, then CC' can recover from errors in SS. Specializing this to RM codes and using our results for erasures imply our result on unique decoding of RM codes at high rate. Finally, two of our capacity achieving results require tight bounds on the weight distribution of RM codes. We obtain such bounds extending the recent \cite{KLP} bounds from constant degree to linear degree polynomials

    Propofol-alfentanil vs propofol-remifentanil for posterior spinal fusion including wake-up test

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    Background. Wake-up test can be used during posterior spinal fusion (PSF) to ensure that spinal function remains intact. This study aims at assessing the characteristics of the wake-up test during propofol-alfentanil (PA) vs propofol-remifentanil (PR) infusions for PSF surgery. Methods. Sixty patients with scoliosis and candidates for PSF surgery were randomly allocated in either alfentanil (PA) or remifentanil (PR) group. After an i.v. bolus of alfentanil 30 μg kg-1 in the PA group or remifentanil 1 μg kg-1 in the PR group, anaesthesia was induced with thiopental and atracurium. During maintenance, opioid infusion consisted of alfentanil 1 μg kg-1 min-1 or remifentanil 0.2 μg kg-1 min-1, in the PA group and the PR group, respectively. All patients received propofol 50 μg kg-1 min-1. Atracurium was given to maintain the required surgical relaxation. At the surgeon's request, all infusions were discontinued. Patients were asked to move their hands and feet. Time from anaesthetic discontinuation to spontaneous ventilation (T1), and from then until movement of the hands and feet (T2), and its quality were recorded. Results. The average T1 and T2 were significantly shorter in the PR group 3.6 (2.5) and 4.1 (2) min than the PA group 6.1 (4) and 7.5 (4.5) min. Quality of wake-up test, however, did not show significant difference between the two groups studied. Conclusion. Wake-up test can be conducted faster with remifentanil compared with alfentanil infusion during PSF surgery. © 2006 Oxford University Press

    Buprenorphine added on brief cognitive behavioral therapy for treatment of methamphetamine use disorder

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    Background: Methamphetamine (MA) use remains a major public health concern around the world. Recent findings suggest that buprenorphine may be helpful for cocaine use reduction. Moreover, animal studies described reduced dopamine peak effect following MA use, due to the administration of low dose buprenorphine. Objectives: This study examined the effectiveness of buprenorphine with brief cognitive behavioral therapy on MA use disorder. Methods: The study was conducted in an outpatient substance abuse treatment center in Qazvin, Iran. Nineteen MA users received buprenorphine for 24 weeks combined with brief cognitive behavioral therapy in an outpatient substance abuse treatment program, three times per week, as a before and after non - randomization study. Clinical outcomes included treatment retention, MA use, degree of MA dependency and craving, quality of life, cognitive abilities questionnaire, addiction severity and also adverse events. Data was analyzed by performing repeated measures analysis and the Friedman test for nonparametric variables. Results: Fifteen participants completed the study during six months and frequency of MA use was significantly decreased at 24 weeks (P < 0.001). There were also significant reductions in craving (P < 0.001), degree of MA dependence (P < 0.001), and improvements in quality of life, cognitive ability, and some subscales of addiction severity. Conclusions: The results of this preliminary clinical study demonstrated that buprenorphine could potentially attenuate MA craving and alternate rewarding effects of MA and had promising effects on cognitive impairment. Furthermore, buprenorphine can be considered as a harm reduction intervention in some communities, in which the people, as a result of cultural beliefs, do not accept a therapy, which only consists of counseling and no medications

    Electric Current Focusing Efficiency in Graphene Electric Lens

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    In present work, we theoretically study the electron wave's focusing phenomenon in a single layered graphene pn junction(PNJ) and obtain the electric current density distribution of graphene PNJ, which is in good agreement with the qualitative result in previous numerical calculations [Science, 315, 1252 (2007)]. In addition, we find that for symmetric PNJ, 1/4 of total electric current radiated from source electrode can be collected by drain electrode. Furthermore, this ratio reduces to 3/16 in a symmetric graphene npn junction. Our results obtained by present analytical method provide a general design rule for electric lens based on negative refractory index systems.Comment: 13 pages, 7 figure

    BASE DEFICIT IN IMMEDIATE POSTOPERATIVE PERIOD OF OPEN HEART SURGERY AND OUTCOME OF PATIENTS

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    Abstract- Base deficit is a non-respiratory indicator of acid base status. Aim of this study is to assess relationship between the base deficit value in immediate post operative period of CABG and valvular heart disease with cardiopulmonary and in hospital outcome of patient. A total of 136 consecutive with CABG and valvular heart disease scheduled in study. 20 variables were determined during the pre-intraand postoperative period. Statistical univariate analysis was performed differentiating patients whose initial base deficit after weaning from cardiopulmonary bypass was -8 meq and these whose base deficit was equal or more than -8 meq. Secondly a logistic regression model was performed on the variables shown to have a statistically significant difference in univariate analysis with determination of the odd ratio. 3 variables had a statistically significant difference in univariate analysis and 2 of them high lighted by the linear logistic model. The value of base deficit measured during the immediate postoperative open-heart surgery is correlated with volume of fresh frozen plasma and blood transfusion after open heart surgery and using of intra aortic balloon pump after surgery

    Efficacy of fentanyl transdermal patch in the treatment of chronic soft tissue cancer pain

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    Background: Cancer pain may be a major problem for health care providers worldwide. According to different studies reporting the pain severity, one-third of patients reported to have moderate to severe pain. Management of cancer pain is one of the most important goals of palliative care. Recently, different research results on the efficacy of opioid analgesics in chronic pain management have played a role to implement standards in pain control by government agencies worldwide. Objectives: This study aimed to investigate the efficacy of fentanyl transdermal patch in the treatment of chronic soft tissue cancer pain. Patients and Methods: In a prospective descriptive study, we evaluated 86 patients with soft tissue tumors with chronic pain referred to cancer institute of Imam Khomeini Hospital, Tehran, Iran, during 2006-2007. For all patients, transdermal fentanyl patch (25 μg/h) was administered. The appearance of patches was the same. Pain severity was measured by Visual Analogue Scale (VAS) initially and 24, 48 and 72 hours after the initiation of treatment. Results: Patients' characteristics and VAS score before the treatment were not significantly different (P > 0.05). According to our findings, the pain severity was significantly reduced after the treatment (P = 0.001). The incidence of adverse events in patients was significantly high (72). The most common adverse events were sleepiness, nausea and vomiting in 30.2 and 18.6, respectively. Conclusions: Transdermal fentanyl patch was an effective and safe method to reduce pain in patients with soft tissue tumors. Moreover, it could improve the quality of life in these patients, but adverse events occurred in approximately 72 of patients. © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM)
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