102 research outputs found

    A decision support framework to assess and prioritize recovery actions for salmon in the Puget Sound

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    Protecting functioning habitats and restoring degraded habitats are critical actions for salmon and Puget Sound recovery. Restoration alone cannot keep up with habitat loss and water quality degradation from development and the pressures of anticipated population growth and future climate. We need a framework for prioritizing diverse projects and programs that takes into account the complexity of the science, competing stakeholder goals, treaty obligations, and the need for regulatory harmonization. As part of the Tulalip Tribes Harmonization project, we present a decision support framework based on three core principles. First the framework must assess ecosystem conditions across diverse indicators and co-benefits. Second, the framework must simulate the effects of diverse actions and trends - including regulatory, restoration, and future pressures on ecosystems. Finally, the framework must be flexible and open as the expertise to build, maintain, sustain, and evolve indicator models will always be spread across a wide swath of scientists, stakeholders, managers and regulators, resulting in many independent systems that should be leveraged by the framework, not recreated. The framework is built on the Ecosystem Management Decision Support system (EMDS) developed by the USDA Forest Service over 25 years ago. We describe the architecture of the framework and report on a concept project that used it to evaluate designs for a transportation project in Snohomish county. This will illustrate both the workflow paradigm of framework and how it can work with an external, specialized indicator modeling system, the Ecosystem Diagnosis and Treatment (EDT) system. The habitat model was used to estimate the value of habitat and key population indicators for Chinook salmon in response to multiple project designs. Finally, we lay out the iterative (in scale, indicators, modeling and action types) plan for development of the framework over the next decade, emphasizing use cases and challenges

    Repair of Noise-Induced Damage to Stereocilia F-Actin Cores Is Facilitated by XIRP2 and Its Novel Mechanosensor Domain

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    Prolonged exposure to loud noise has been shown to affect inner ear sensory hair cells in a variety of deleterious manners, including damaging the stereocilia core. The damaged sites can be visualized as \u27gaps\u27 in phalloidin staining of F-actin, and the enrichment of monomeric actin at these sites, along with an actin nucleator and crosslinker, suggests that localized remodeling occurs to repair the broken filaments. Herein, we show that gaps in mouse auditory hair cells are largely repaired within 1 week of traumatic noise exposure through the incorporation of newly synthesized actin. We provide evidence that Xin actin binding repeat containing 2 (XIRP2) is required for the repair process and facilitates the enrichment of monomeric γ-actin at gaps. Recruitment of XIRP2 to stereocilia gaps and stress fiber strain sites in fibroblasts is force-dependent, mediated by a novel mechanosensor domain located in the C-terminus of XIRP2. Our study describes a novel process by which hair cells can recover from sublethal hair bundle damage and which may contribute to recovery from temporary hearing threshold shifts and the prevention of age-related hearing loss

    Developmental time course of peripheral cross‐modal sensory interaction of the trigeminal and gustatory systems

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    Few sensory modalities appear to engage in cross‐modal interactions within the peripheral nervous system, making the integrated relationship between the peripheral gustatory and trigeminal systems an ideal model for investigating cross‐sensory support. The present study examined taste system anatomy following unilateral transection of the trigeminal lingual nerve (LX) while leaving the gustatory chorda tympani intact. At 10, 25, or 65 days of age, rats underwent LX with outcomes assessed following various survival times. Fungiform papillae were classified by morphological feature using surface analysis. Taste bud volumes were calculated from histological sections of the anterior tongue. Differences in papillae morphology were evident by 2 days post‐transection of P10 rats and by 8 days post in P25 rats. When transected at P65, animals never exhibited statistically significant morphological changes. After LX at P10, fewer taste buds were present on the transected side following 16 and 24 days survival time and remaining taste buds were smaller than on the intact side. In P25 and P65 animals, taste bud volumes were reduced on the denervated side by 8 and 16 days postsurgery, respectively. By 50 days post‐transection, taste buds of P10 animals had not recovered in size; however, all observed changes in papillae morphology and taste buds subsided in P25 and P65 rats. Results indicate that LX impacts taste receptor cells and alters epithelial morphology of fungiform papillae, particularly during early development. These findings highlight dual roles for the lingual nerve in the maintenance of both gustatory and non‐gustatory tissues on the anterior tongue. © 2015 Wiley Periodicals, Inc. Develop Neurobiol 76: 626–641, 201

    Theory and applications mathematics for elementary school teachers

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    xxxv, 402 p.; 24 cm

    On Group Algebras of Prime Power Groups

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    40 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1953.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD

    Theory and application of mathematics for elementary school teachers/ Hashisaki

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    xxxv, 402 hal: ill.; 24 cm

    Use of an Open Knowledge Network for the Salish Sea

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    We face more and greater challenges with a new sense of urgency. Science organizations have long recognized the need for data management and curation to support decision making. However, the information needed today to make resource decisions goes beyond data and models. It also includes people, their knowledge and values, needs of programs and projects, funding, geographic information, and more. This panel discusses the use of an Open Knowledge Network (OKN) for the Salish Sea, an open technology platform for finding, sharing, and accessing information and tools for decision making. Panelists will describe one such OKN, the Social Ecological Open Network (SEON)and illustrate its use via a ‘knowledge manager’ interface co-developed by the Suquamish Tribe. Three applications of the SEON will be presented; 1) a project level application, addressing the Tulalip Tribes’ prioritizing of culvert repairs in King County; 2) a program level application, supported by the Suquamish Tribe, presenting an online permit review system that links proposed development with vulnerable natural resources and regulations,; and 3) a regional scale education application, connecting students and entrepreneurs, especially those furthest from opportunity, to the larger restoration community to build career pathways, including training, information, and social networks for entering the green economy. We will also describe how an open knowledge network like SEON can be utilized in decision support tools for comprehensive planning. Following Q&A discussions, the closing speaker will discuss the broader importance of an OKN for the Puget Sound Region, the need for pilots and case studies, the hope for more collaboration to break down barriers and to build and sustain a Salish Sea SEON across disciplines and diverse communities
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