Dynamic and static task allocation for hard real-time video stream decoding on NoCs

Hard real-time (HRT) video systems require admission control decisions that rely on two factors. Firstly, schedulability analysis of the data-dependent, communicating tasks within the application need to be carried out in order to guarantee timing and predictability. Secondly, the allocation of the tasks to multi-core processing elements would generate different results in the schedulability analysis. Due to the conservative nature of the state-of-the-art schedulability analysis of tasks and message lows, and the unpredictability in the application, the system resources are often under-utilised. In this paper we propose two blocking-aware dynamic task allocation techniques that exploit application and platform characteristics, in order to increase the number of simultaneous, fully schedulable, video streams handled by the system. A novel, worst-case response time aware, search-based, static hard real-time task mapper is introduced to act as an upper-baseline to the proposed techniques. Further evaluations are carried out against existing heuristic-based dynamic mappers. Improvements to the admission rates and the system utilisation under a range of different workloads and platform sizes are explored

Variation and signatures of selection on the human face

AbstractThere has been much debate about why humans throughout the world differ in facial form. Previous studies of human skull morphology found levels of among-population differentiation that were comparable to those of neutral genetic markers, suggesting that genetic drift (neutral processes) played an important role in influencing facial differentiation. However, variation in soft-tissue morphology has not been studied in detail. In this study, we analyzed high-resolution 3D images of soft-tissue facial form in four Eurasian populations: Han Chinese, Tibetans, Uyghur and Europeans. A novel method was used to establish a high-density alignment across all of the faces, allowing facial diversity to be examined at an unprecedented resolution. These data exhibit signatures of population structure and history. However, among-population differentiation was higher for soft-tissue facial form than for genome-wide genetic loci, and high-resolution analyses reveal that the nose, brow area and cheekbones exhibit particularly strong signals of differentiation (Qst estimates: 0.3–0.8) between Europeans and Han Chinese. Our results suggest that local adaptation and/or sexual selection have been important in shaping human soft-tissue facial morphology

A Resource and policy aware VM scheduler for medium-scale clouds

Medium-scale private clouds are being widely used in enterprises and universities. While, these clouds have a relatively small pool of resources, diversity of those resources, users, and their needs are still comparable with public clouds. We present a resource and policy aware Virtual Machine (VM) scheduling solution for such medium-scale clouds. The proposed scheduler enables the deployment of VMs based on a predefined set of policies and user priorities, while being aware of the resource utilization of the cloud. This is achieved by periodically polling resource statistics from the cloud nodes, enforcing a set of predefined policies, taking into account the priority levels of users and VM requests, and then scaling, migrating, and preempting VMs based on available resources and policies. Such resource and policy aware scheduling improves resource request acceptance rate and increases the utilization of cloud resources. A proof of concept solution is implemented using Apache CloudStack and validated against a carefully crafted set of resource requests

Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM-HET3 mice

The aging brain is characterized by progressive increases in neuroinflammation and central insulin resistance, which contribute to neurodegenerative diseases and cognitive impairment. Recently, the Interventions Testing Program demonstrated that the anti-diabetes drug, Canagliflozin (Cana), a sodium-glucose transporter 2 inhibitor, led to lower fasting glucose and improved glucose tolerance in both sexes, but extended median lifespan by 14% in male mice only. Here, we show that Cana treatment significantly improved central insulin sensitivity in the hypothalamus and the hippocampus of 30-month-old male mice. Aged males produce more robust neuroimmune responses than aged females. Remarkably, Cana-treated male and female mice showed significant reductions in age-associated hypothalamic gliosis with a decrease in inflammatory cytokine production by microglia. However, in the hippocampus, Cana reduced microgliosis and astrogliosis in males, but not in female mice. The decrease in microgliosis was partially correlated with reduced phosphorylation of S6 kinase in microglia of Cana-treated aged male, but not female mice. Thus, Cana treatment improved insulin responsiveness in aged male mice. Furthermore, Cana treatment improved exploratory and locomotor activity of 30-month-old male but not female mice. Taken together, we demonstrate the sex-specific neuroprotective effects of Cana treatment, suggesting its application for the potential treatment of neurodegenerative diseases.Our findings demonstrate sex-specific neuroprotective effects of Canagliflozin treatment that are associated with reduced neuroinflammation, improved central insulin sensitivity, and locomotor activity in aged mice.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/173068/1/ACEL13653-sup-0001-supinfo.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/173068/2/acel13653.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/173068/3/acel13653_am.pd

A Sustainable Advance Payment Scheme for Deteriorating Items with Preservation Technology

Profitably managing inventories is always a big challenge for retailers in the current context of transparent and competitive business. A general retailer always needs to handle both deteriorating and non-deteriorating products simultaneously to run a business. Deterioration of products sometimes impacts a retailer’s profits badly—a situation which can be alleviated by implementing proper preservation technology. In addition, to improve profits and minimize costs, a retailer always seeks some credit facilities (e.g., advance payment, trade credit facilities, etc.) from the supplier to continue the business smoothly with minimum investment. Advance payment is renowned for preventing the possibility of business orders being canceled and helping the retailer to minimize the risk of investing significant amounts at a single time. The foremost objective of this research is to analyze the facilities of advance payment and preservation technology investment and concurrent attempts to deal with shortages. This study shows that, given the presence of preservation technology, the result of case II is 68.06% higher than that of case I, whereas when preservation technology is absent, the result of case II is 71.93% higher than that of case I. The managerial insights of this analysis reveal that preservation technology attempts to prolong product life by preventing deterioration, which contributes to the retailer’s profitable business. On the other hand, in the case of an advance payment scheme, although the costs are relatively high, the study emphasizes the importance of the advance payment facility as it limits the risk of order cancellation and makes business more flexible for both supplier and retailer. The proposed model is solved by the classical optimization technique. Some theoretical derivations with numerical analysis support the model and provide some managerial insights for practitioners

Study Protocol for a Global Survey: Awareness and Preparedness of Hospital Staff Against Coronavirus Disease (COVID-19) Outbreak

Background: The outbreak of Coronavirus disease (COVID-19) caused by a novel coronavirus (named SARS-CoV-2) has gained attention globally and has been recognized as a Public Health Emergency of International Concern (PHEIC) by the World Health Organization (WHO) due to the rapidly increasing number of deaths and confirmed cases. Health care workers (HCWs) are vulnerable to this crisis as they are the first frontline to receive and manage COVID-19 patients. In this multicenter multinational survey, we aim to assess the level of awareness and preparedness of hospital staff regarding COVID-19 all over the world.Methods: From February to March 2020, the web-based or paper-based survey to gather information about the hospital staff\u27s awareness and preparedness in the participants\u27 countries will be carried out using a structured questionnaire based on the United States Centers for Disease Control and Prevention (CDC) checklist and delivered to participants by the local collaborators for each hospital. As of March 2020, we recruited 374 hospitals from 58 countries that could adhere to this protocol as approved by their Institutional Review Boards (IRB) or Ethics Committees (EC).Discussion: The awareness and preparedness of HCWs against COVID-19 are of utmost importance not only to protect themselves from infection, but also to control the virus transmission in healthcare facilities and to manage the disease, especially in the context of manpower lacking and hospital overload during the pandemic. The results of this survey can be used to inform hospitals about the awareness and preparedness of their health staff regarding COVID-19, so appropriate policies and practice guidelines can be implemented to improve their capabilities of facing this crisis and other future pandemic-prone diseases.</jats:p