A theory of one-dimensional fracture

A completely analytical theory is developed for the mixed mode partition of one-dimensional fracture in laminated composite beams and plates. Two sets of orthogonal pure modes are determined first. It is found that they are distinct from each other in Euler beam or plate theory and coincide at the Wang-Harvey set in Timoshenko beam or plate theory. After the Wang- Harvey set is proved to form a unique complete orthogonal pure mode basis within the contexts of both Euler and Timoshenko beam or plate theories, it is used to partition a mixed mode. Stealthy interactions are found between the Wang-Harvey pure mode I modes and mode II modes in Euler beam or plate theory, which alter the partitions of a mixed mode. The finite element method is developed to validate the analytical theories

Overlapping functionality of the Pht proteins in zinc homeostasis of streptococcus pneumoniae

Streptococcus pneumoniae is a globally significant pathogen that causes a range of diseases, including pneumonia, sepsis, meningitis, and otitis media. Its ability to cause disease depends upon the acquisition of nutrients from its environment, including transition metal ions such as zinc. The pneumococcus employs a number of surface proteins to achieve this, among which are four highly similar polyhistidine triad (Pht) proteins. It has previously been established that these proteins collectively aid in the delivery of zinc to the ABC transporter substrate-binding protein AdcAII. Here we have investigated the contribution of each individual Pht protein to pneumococcal zinc homeostasis by analyzing mutant strains expressing only one of the four pht genes. Under conditions of low zinc availability, each of these mutants showed superior growth and zinc accumulation profiles relative to a mutant strain lacking all four genes, indicating that any of the four Pht proteins are able to facilitate delivery of zinc to AdcAII. However, optimal growth and zinc accumulation in vitro and pneumococcal survival and proliferation in vivo required production of all four Pht proteins, indicating that, despite their overlapping functionality, the proteins are not dispensable without incurring a fitness cost. We also show that surface-attached forms of the Pht proteins are required for zinc recruitment and that they do not contribute to defense against extracellular zinc stress

One Love: Explicit Monogamy Agreements among Heterosexual Young Adult Couples at Increased Risk of Sexually Transmitted Infections

HIV prevention strategies among couples include condom use, mutual monogamy, and HIV testing. Research suggests that condom use is more likely with new or casual partners, and tends to decline as relationships become steady over time. Little is known, however, about explicit mutual monogamy agreements and HIV testing within heterosexual couples. This study used data from 434 young heterosexual couples at increased risk of HIV and sexually transmitted infections (STIs) to assess (a) couple concordance on perceptions of a monogamy agreement, sustained monogamy, and HIV testing; and (b) the associations of relationship and demographic factors with monogamy agreement, sustained monogamy, and HIV testing. Results indicated only slight to fair agreement within couples on measures of monogamy agreement and sustained monogamy. Overall, 227 couples (52%) concurred that they had an explicit agreement to be monogamous; of those, 162 (71%) had sustained the agreement. Couples with greater health protective communication and commitment were more likely to have a monogamy agreement. Couples of Latino and Hispanic ethnicity and those with children were less likely to have a monogamy agreement. Only commitment was related to sustained monogamy. Having children, greater health protective communication, and perceived vulnerability to HIV and STIs were associated with HIV testing within the couple

Drawing On College Student Attitudes and Behaviors to Instigate Energy Efficiency Improvements in Rental Housing

Improving the energy efficiency of residential rental properties has been a priority of Cornell Cooperative Extension of Tompkins County. However, traditional educational programming has had limited effectiveness due to a split incentive dynamic between landlords and tenants relative to property upgrades. We demonstrate that college students have broad interest in but limited knowledge of energy efficiency and are willing to pay a premium for relevant improvements. Our findings indicate that there is strong potential for Extension professionals to engage off-campus housing offices, students, and landlords in the development of modified leases and to facilitate educational programming that specifically addresses rental housing energy efficiency

The Herschel Digit Survey Of Weak-Line T Tauri Stars: Implications For Disk Evolution And Dissipation

As part of the "Dust, Ice, and Gas In Time (DIGIT)" Herschel Open Time Key Program, we present Herschel photometry (at 70, 160, 250, 350, and 500 mu m) of 31 weak-line T Tauri star (WTTS) candidates in order to investigate the evolutionary status of their circumstellar disks. Of the stars in our sample, 13 had circumstellar disks previously known from infrared observations at shorter wavelengths, while 18 of them had no previous evidence for a disk. We detect a total of 15 disks as all previously known disks are detected at one or more Herschel wavelengths and two additional disks are identified for the first time. The spectral energy distributions (SEDs) of our targets seem to trace the dissipation of the primordial disk and the transition to the debris disk regime. Of the 15 disks, 7 appear to be optically thick primordial disks, including 2 objects with SEDs indistinguishable from those of typical Classical T Tauri stars, 4 objects that have significant deficit of excess emission at all IR wavelengths, and 1 "pre-transitional" object with a known gap in the disk. Despite their previous WTTS classification, we find that the seven targets in our sample with optically thick disks show evidence for accretion. The remaining eight disks have weaker IR excesses similar to those of optically thin debris disks. Six of them are warm and show significant 24 mu m Spitzer excesses, while the last two are newly identified cold debris-like disks with photospheric 24 mu m fluxes, but significant excess emission at longer wavelengths. The Herschel photometry also places strong constraints on the non-detections, where systems with F-70/F-70,(*) greater than or similar to 5-15 and L-disk/L-* greater than or similar to 10(-3) to 10(-4) can be ruled out. We present preliminary models for both the optically thick and optically thin disks and discuss our results in the context of the evolution and dissipation of circumstellar disks.NASA through JPL/CaltechNASA through the Sagan Fellowship ProgramEuropean Commission PERG06-GA-2009-256513Agence Nationale pour la Recherche (ANR) of France ANR-2010-JCJC-0504-01CFHT 11AH96Astronom