29,024 research outputs found

    Observations of Cavitation on a Three-Dimensional Oscillating Hydrofoil

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    A test apparatus was designed and constructed to observe the effect of sinusoidal pitching oscillations on the cavitation of three-dimensional hydrofoils. The apparatus is capable of oscillating hydrofoils at a rate up to 50 Hz and provides for adjustments in oscillation amplitude and mean angle of attack. Observations of the effect of pitching oscillation on cavitation have been made for a NACA 64-309 (modified) hydrofoil operating at its designed mean angle of attack of 7 degrees with an oscillation amplitude of 2 degrees. Photographs illustrating the interaction between natural cavity shedding frequencies and the foil reduced frequency are included

    Psychological stress and cardiovascular disease: empirical demonstration of bias in a prospective observational study of Scottish men

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    Objectives: To examine the association between self perceived psychological stress and cardiovascular disease in a population where stress was not associated with social disadvantage. Design: Prospective observational study with follow up of 21 years and repeat screening of half the cohort 5 years from baseline. Measures included perceived psychological stress, coronary risk factors, self reported angina, and ischaemia detected by electrocardiography. Setting: 27 workplaces in Scotland. Participants: 5606 men (mean age 48 years) at first screening and 2623 men at second screening with complete data on all measures Main outcome measures: Prevalence of angina and ischaemia at baseline, odds ratio for incident angina and ischaemia at second screening, rate ratios for cause specific hospital admission, and hazard ratios for cause specific mortality. Results: Both prevalence and incidence of angina increased with increasing perceived stress (fully adjusted odds ratio for incident angina, high versus low stress 2.66, 95% confidence interval 1.61 to 4.41; P for trend <0.001). Prevalence and incidence of ischaemia showed weak trends in the opposite direction. High stress was associated with a higher rate of admissions to hospital generally and for admissions related to cardiovascular disease and psychiatric disorders (fully adjusted rate ratios for any general hospital admission 1.13, 1.01 to 1.27, cardiovascular disease 1.20, 1.00 to 1.45, and psychiatric disorders 2.34, 1.41 to 3.91). High stress was not associated with increased admission for coronary heart disease (1.00, 0.76-1.32) and showed an inverse relation with all cause mortality, mortality from cardiovascular disease, and mortality from coronary heart disease, that was attenuated by adjustment for occupational class (fully adjusted hazard ratio for all cause mortality 0.94, 0.81 to 1.11, cardiovascular mortality 0.91, 0.78 to 1.06, and mortality from coronary heart disease 0.98, 0.75 to 1.27). Conclusions: The relation between higher stress, angina, and some categories of hospital admissions probably resulted from the tendency of participants reporting higher stress to also report more symptoms. The lack of a corresponding relation with objective indices of heart disease suggests that these symptoms did not reflect physical disease. The data suggest that associations between psychosocial measures and disease outcomes reported from some other studies may be spurious

    Limitations of adjustment for reporting tendency in observational studies of stress and self reported coronary heart disease

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    Recently, observational evidence has been suggested to show a causal association between various "psychosocial" exposures, including psychological stress, and heart disease. Much of this evidence derives from studies in which a self reported psychosocial exposure is related to an outcome dependent on the subjective experience of coronary heart disease (CHD) symptoms. Such outcomes may be measured using standard symptom questionnaires (like the Rose angina schedule). Alternatively they may use diagnoses of disease from medical records, which depend on an individual perceiving symptoms and reporting them to a health worker. In these situations, reporting bias may generate spurious exposure-outcome associations. For example if people who perceive and report their life as most stressful also over-report symptoms of cardiovascular disease then an artefactual association between stress and heart disease will result

    Individual employment histories and subsequent cause specific hospital admissions and mortality: a prospective study of a cohort of male and female workers with 21 years follow up

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    It is a widely held view that the labour market is demanding increased levels of flexibility, and that this is causing greater psychosocial stress among employees.1 Such stress may affect health, either through neuroendocrine pathways, or through increases in behaviours linked with poor health.2 Previously we presented evidence linking an unstable employment history, as measured by a greater number of job changes and shorter duration of current job, with a greater prevalence of smoking and greater alcohol consumption, in male and female workers.3 4 Despite this, we did not observe clear detrimental effects of such instability on health related physiological measures (body mass index, diastolic blood pressure, cholesterol, and lung function), nor on current cardiovascular health (electrocardiogram determined ischaemia and reported symptoms of angina). Finding work is easier for healthy persons, and those persons who need to find work repeatedly will be particularly likely to drop out of the workforce if their health deteriorates. Consequently, an occupational cohort, upon which our previous work was based, is least likely to include people of poor health with an unstable work history. If such people are underrepresented, attempts to determine the association between health and individual work histories will mislead. This study links the same cohort to information on the hospitalisations and deaths experienced over a 21 year follow up period. While those people whose health deteriorated before the enrolment of this cohort must remain poorly represented, these prospective data permit unbiased observation of those cases who experienced ill health subsequently, whether or not this resulted in an exit from the workforce. We hypothesise that an employment history characterised by frequent job changes, whatever the motivation for those changes, will require the person to be more focused on work, and less focused on maintaining personal health, with consequent poorer health for such people

    Loss of redundant gene expression after polyploidization in plants

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    Based on chromosomal location data of genes encoding 28 biochemical systems in allohexaploid wheat,Triticum aestivum L. (genomes AABBDD), it is concluded that the proportions of systems controlled by triplicate, duplicate, and single loci are 57%, 25%, and 18% respectively

    Cause-specific hospital admission and mortality among working men: association with socioeconomic circumstances in childhood and adult life, and the mediating role of daily stress

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    BACKGROUND: The aim of this study was to investigate the association of childhood and adulthood social class with the occurrence of specific diseases, including those not associated with a high mortality rate, and to investigate daily stress as the mechanism for that part of any association which cannot be accounted for by established risk factors. METHODS: This was a prospective cohort study with 25 years of follow-up for cause-specific morbidity and mortality. A total of 5577 Scottish men were recruited from 27 workplaces in the West of Scotland. Childhood social class was determined from the occupation held by the individual's father, and adulthood social class from the individual's occupation at enrolment. Daily stress was measured at enrolment using the Reeder Stress Inventory. RESULTS: Health differentials were found for cardiovascular diseases, lung cancer, peptic ulcer, asthma, accidents and violence, alcohol-related diseases, and perhaps psychiatric illness. Adulthood circumstances were associated with the incidence of most diseases in adulthood, the exception being stroke, which was strongly associated with less privileged circumstances in childhood. Both childhood and adulthood circumstances contributed to the incidence of coronary heart disease. Daily stress did not underlie any of these associations once the influence of established risk factors had been taken into account. CONCLUSIONS: Socioeconomic circumstances in childhood and adulthood both contribute to health differentials in adulthood, the relative contributions depending upon the particular disease. Where known risk factors explained only part of the excess of a disease among individuals raised or living in less-privileged circumstances, there was no evidence to suggest that daily stress was the reason for the unexplained excess

    Voltage controlling mechanisms in low resistivity silicon solar cells: A unified approach

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    An experimental technique capable of resolving the dark saturation current into its base and emitter components is used as the basis of an analysis in which the voltage limiting mechanisms were determined for a variety of high voltage, low resistivity silicon solar cells. The cells studied include the University of Florida hi-low emitter cell, the NASA and the COMSAT multi-step diffused cells, the Spire Corporation ion-implanted emitter cell, and the University of New South Wales MINMIS and MINP cells. The results proved to be, in general, at variance with prior expectations. Most surprising was the finding that the MINP and the MINMIS voltage improvements are due, to a considerable extent, to a previously unrecognized optimization of the base component of the saturation current. This result is substantiated by an independent analysis of the material used to fabricate these devices

    Decentralised systemising of Scholarship of Engagement in higher education towards societal impact

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    In this article, a case study is presented for the development of a Scholarship of Engagement (SoE) engagement database, to map the engagement footprint of the university, and develop a Knowledge Management System (KMS) at the University of the Western Cape (UWC), in order to facilitate the process of knowledge sharing. The aim of this article is to discuss a process of creating baseline data, to explore and profile the institution’s SoE landscape, and facilitate a decentralised system of the SoE, based on an integrated approach to the institutionalisation of the SoE. The sharing of exemplars are important; consequently, in this article the context and role of the Community Engagement Unit (CEU), as well as the motivation for embarking on the project are explained. Additionally, the process from conceptualization, through implementation, to reflections on lessons learnt, and the future path of decentralisation, are plotted and documented. All partners pilot an integrative approach to implementation, to facilitate acceptance and uptake, while enablers that facilitate the process are identified, and decentralisation for the protection of academic freedom is highlighted. This case study is relevant to other universities, especially those on the African continent, as we attend to the broader decolonialisation agenda, which presents an exemplar for the duplication, adaptation, and creation of a SoE database, for universities to profile and present their anchoring in communities, following the principles of engagement that are aligned to transformation and social justice

    A model for scholarship of engagement institutionalization and operationalization

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    Transformation policies have been a high priority for governments globally, regionally, and nationally to address past inequalities. Higher Education Institutions (HEIs) are the critical stakeholders that ensure societal transformation. This requires HEIs to reimagine community engagement, with a necessary role-shift from Mode 1: provider of disciplinary knowledge to Mode 2: distributor of knowledge to broader society through engagement and research that is inclusive and impactful. In this article, we present an adapted version of Boyer’s Scholarship of Engagement (SoE) model, to assist HEIs with the institutionalization and operationalization of engaged scholarship, inclusive of some factors and examples to consider for the process. The operationalization of the model helps HEIs to progress toward assessing their SoE effectiveness and, ultimately, their Societal Impact (SI) contribution, to transform society, responsively and responsibly
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