A Superwind from Early Post-Red Giant Stars?

We suggest that the gap observed at 20,000 K in the horizontal branches of several Galactic globular clusters is caused by a small amount of extra mass loss which occurs when stars start to "peel off" the red giant branch (RGB), i.e., when their effective temperature starts to increase, even though they may still be on the RGB. We show that the envelope structure of RGB stars which start to peel off is similar to that of late asymptotic giant branch stars known to have a super-wind phase. An analogous super-wind in the RGB peel-off stars could easily lead to the observed gap in the distribution of the hottest HB stars.Comment: 9 pages; Accepted by ApJ Letters; Available also at http://www.astro.puc.cl/~mcatelan

Coupled climate model simulations of Mediterranean winter cyclones and large-scale flow patterns

The study aims to evaluate the ability of global, coupled climate models to reproduce the synoptic regime of the Mediterranean Basin. The output of simulations of the 9 models included in the IPCC CMIP3 effort is compared to the NCEP-NCAR reanalyzed data for the period 1961–1990. The study examined the spatial distribution of cyclone occurrence, the mean Mediterranean upper- and lower-level troughs, the inter-annual variation and trend in the occurrence of the Mediterranean cyclones, and the main large-scale circulation patterns, represented by rotated EOFs of 500 hPa and sea level pressure. The models reproduce successfully the two maxima in cyclone density in the Mediterranean and their locations, the location of the average upper- and lower-level troughs, the relative inter-annual variation in cyclone occurrences and the structure of the four leading large scale EOFs. The main discrepancy is the models' underestimation of the cyclone density in the Mediterranean, especially in its western part. The models' skill in reproducing the cyclone distribution is found correlated with their spatial resolution, especially in the vertical. The current improvement in model spatial resolution suggests that their ability to reproduce the Mediterranean cyclones would be improved as well

Defining the Termination of the Asymptotic Giant Branch

I suggest a theoretical quantitative definition for the termination of the asymptotic giant branch (AGB) phase and the beginning of the post-AGB phase. I suggest that the transition will be taken to occur when the ratio of the dynamical time scale to the the envelope thermal time scale, Q, reaches its maximum value. Time average values are used for the different quantities, as the criterion does not refer to the short time-scale variations occurring on the AGB and post-AGB, e.g., thermal pulses (helium shell flashes) and magnetic activity. Along the entire AGB the value of Q increases, even when the star starts to contract. Only when a rapid contraction starts does the value of Q start to decrease. This criterion captures the essence of the transition from the AGB to the post AGB phase, because Q is connected to the stellar effective temperature, reaching its maximum value at T~4000-6000 K, it is related to the mass loss properties, and it reaches its maximum value when rapid contraction starts and envelope mass is very low.Comment: Submitted to ApJ Letter

Detection of a period decrease in NN Ser with ULTRACAM: evidence for strong magnetic braking or an unseen companion?

We present results of high time resolution photometry of the eclipsing pre-cataclysmic variable NN Ser. We observed 13 primary eclipses of NN Ser using the high-speed CCD camera ULTRACAM and derived times of mid-eclipse, from fitting of light curve models, with uncertainties as low as 0.06 s. The observed rates of period change appear difficult to reconcile with any models of orbital period change. If the observed period change reflects an angular momentum loss, the average loss rate is consistent with the loss rates (via magnetic stellar wind braking) used in standard models of close binary evolution, which were derived from observations of much more massive cool stars. Observations of low-mass stars such as NN Ser's secondary predict rates of ~100 times lower than we observe. We show that magnetic activity-driven changes in the quadrupole moment of the secondary star (Applegate, 1992) fail to explain the period change by an order of magnitude on energetic grounds, but that a light travel time effect caused by the presence of a third body in a long (~ decades) orbit around the binary could account for the observed changes in the timings of NN Ser's mid-eclipses. We conclude that we have either observed a genuine angular momentum loss for NN Ser, in which case our observations pose serious difficulties for the theory of close binary evolution, or we have detected a previously unseen low-mass companion to the binary.Comment: 10 pages, 6 figures. Accepted for publication in MNRA

Why Magnetic Fields Cannot be the Main Agent Shaping Planetary Nebulae

An increasing amount of literature reports the detection of magnetic fields in asymptotic giant branch (AGB) stars and in central stars of planetary nebulae (PNs). These detections lead to claims that the magnetic fields are the main agent shaping the PNs. In this paper, I examine the energy and angular momentum carried by magnetic fields expelled from AGB stars, as well as other physical phenomena that accompany the presence of large scale fields, such as those claimed in the literature. I show that a single star cannot supply the energy and angular momentum if the magnetic fields have the large coherent structure required to shape the circumstellar wind. Therefore, the structure of non-spherical planetary nebulae cannot be attributed to dynamically important large scale magnetic fields. I conclude that the observed magnetic fields around evolved stars can be understood by locally enhanced magnetic loops which can have a secondary role in the shaping of the PN. The primary role, I argue, rests with the presence of a companion.Comment: PASP, 2006, in press. (This paper was rejected by MNRAS and ApJ; my criticism of the referee reports are in: Soker, N. astro-ph/0508525.

Shaping bipolar Planetary Nebulae : How mass loss leads to waistline development

Asymptotic Giant Branch (AGB) stars generally have spherically symmetric envelopes, whereas most post-AGB stars and Planetary Nebulae (PNe) show axisymmetric circumstellar envelopes. While various mechanisms for axisymmetric circumstellar structures may explain the shapes of PNe, they do not address how the shape of the circumstellar shell evolves. Here we address the temporal changes in the axisymmetry of AGB star envelopes, and in particular the development of the torus required in the Generalized Interacting Stellar Winds (GISW) model. Assuming (1) an AGB star rotates with sufficient angular speed at the start of the AGB phase; and (2) that the rotational angular momentum of the AGB star is conserved, we demonstrate that some very important observational features of AGB star axisymmetry evolution can be reproduced. We find that, compared to the star's increasing luminosity and decreasing effective temperature, the decreasing mass of the star primarily affects the axisymmetry of the envelope. When a representative mass loss history is adopted, where most of the mass is lost near the end of the AGB phase, the envelope's axisymmetry increases over time, with the strongest increase occurring near the end of the AGB phase. This may naturally explain why most AGB stars have spherically symmetric envelopes, while axisymmetry seems common-place in the post-AGB/PNe phase. The degree of axisymmetry at the end of the AGB phase is found to increase with increasing main sequence mass, and the onset of axisymmetry occurs only after the onset of the superwind (SW) phase, in good agreement with the observations.Comment: 15 pages, 2 figures, accepted by Ap

The Galactic Population of Low- and Intermediate-Mass X-ray Binaries

(abridged) We present the first study that combines binary population synthesis in the Galactic disk and detailed evolutionary calculations of low- and intermediate-mass X-ray binaries (L/IMXBs). We show that the formation probability of IMXBs with initial donor masses of 1.5--4 Msun is typically >~5 times higher than that of standard LMXBs, and suggest that the majority of the observed systems may have descended from IMXBs. Distributions at the current epoch of the orbital periods, donor masses, and mass accretion rates have been computed, as have orbital-period distributions of BMPs. Several significant discrepancies between the theoretical and observed distributions are discussed. The orbital-period distribution of observed BMPs strongly favors cases where the envelope of the neutron-star progenitor is more easily ejected during the common-envelope phase. However, this leads to a >~100-fold overproduction of the theoretical number of luminous X-ray sources relative to the total observed number of LMXBs. X-ray irradiation of the donor star may result in a dramatic reduction in the X-ray active lifetime of L/IMXBs, thus possibly resolving the overproduction problem, as well as the long-standing BMP/LMXB birthrate problem.Comment: 12 pages, emulateapj, submitted to Ap

Computation of protein geometry and its applications: Packing and function prediction

This chapter discusses geometric models of biomolecules and geometric constructs, including the union of ball model, the weigthed Voronoi diagram, the weighted Delaunay triangulation, and the alpha shapes. These geometric constructs enable fast and analytical computaton of shapes of biomoleculres (including features such as voids and pockets) and metric properties (such as area and volume). The algorithms of Delaunay triangulation, computation of voids and pockets, as well volume/area computation are also described. In addition, applications in packing analysis of protein structures and protein function prediction are also discussed.Comment: 32 pages, 9 figure

PSR J1740-5340: accretion inhibited by radio-ejection in a binary millisecond pulsar in the Globular Cluster NGC 6397

We present an evolutionary scenario for the spin-up and evolution of binary millisecond pulsars, according to which the companion of the pulsar PSR J 1740-5340, recently discovered as a binary with orbital period of 32.5 hr in the Globular Cluster NGC 6397, is presently in a phase of ``radio-ejection'' mass loss from the system. At present, Roche lobe overflow due to the nuclear evolution of the pulsar companion and to systemic angular momentum losses by magnetic braking is still going on, but accretion is inhibited by the momentum exerted by the radiation of the pulsar on the matter at the inner Lagrangian point. The presence of this matter around the system is consistent with the long lasting irregular radio eclipses seen in the system. Roche lobe deformation of the mass losing component is also necessary to be compatible with the optical light curve. The "radio-ejection" phase had been recently postulated by us to deal with the problem of the lack of submillisecond pulsars (Burderi et al. 2001, ApJ, 560, L71).Comment: Accepted for publication in The Astrophysical Journa

Mining multi-item drug adverse effect associations in spontaneous reporting systems

<p>Abstract</p> <p>Background</p> <p>Multi-item adverse drug event (ADE) associations are associations relating multiple drugs to possibly multiple adverse events. The current standard in pharmacovigilance is bivariate association analysis, where each single drug-adverse effect combination is studied separately. The importance and difficulty in the detection of multi-item ADE associations was noted in several prominent pharmacovigilance studies. In this paper we examine the application of a well established data mining method known as association rule mining, which we tailored to the above problem, and demonstrate its value. The method was applied to the FDAs spontaneous adverse event reporting system (AERS) with minimal restrictions and expectations on its output, an experiment that has not been previously done on the scale and generality proposed in this work.</p> <p>Results</p> <p>Based on a set of 162,744 reports of suspected ADEs reported to AERS and published in the year 2008, our method identified 1167 multi-item ADE associations. A taxonomy that characterizes the associations was developed based on a representative sample. A significant number (67% of the total) of potential multi-item ADE associations identified were characterized and clinically validated by a domain expert as previously recognized ADE associations. Several potentially novel ADEs were also identified. A smaller proportion (4%) of associations were characterized and validated as known drug-drug interactions.</p> <p>Conclusions</p> <p>Our findings demonstrate that multi-item ADEs are present and can be extracted from the FDA’s adverse effect reporting system using our methodology, suggesting that our method is a valid approach for the initial identification of multi-item ADEs. The study also revealed several limitations and challenges that can be attributed to both the method and quality of data.</p