Correlation of Sagittal Skeletal malocclusion and Growth patterns between Digital and Conventional Dermatoglyphics

Background: The craniofacial morphology and its growth pattern are determined by the influence of various environmental factors depending on the genetic background. Due to the close association of MSX 1 and SMARCAD gene on the same chromosome, it can be hypothesized that malocclusion and fingerprint pattern are related. Furthermore, it is observed that the orofacial structures originate from the same embryonic tissue as the epidermal ridges, which are the ectoderm. Thus, the simultaneous development of the epidermal ridges and the orofacial structure during this time is deciphered and reflected in the fingerprint patterns. Aim: This study aimed to analyse, compare, and correlate the fingerprint patterns of individuals with different skeletal malocclusions and growth patterns using manual and digital methods. Materials and Methods: Patients (a random sample of 544) who were undergoing orthodontic treatment and were able to give informed consent were included in the study. Informed consent was obtained prior to the start of the procedure, with due regard to ethical issues and the confidentiality of fingerprint records. The anteroposterior jaw relation was determined from the patient's lateral cephalogram with evaluation of the parameters: SNA, ANB, SNB and growth patterns are determined using the mandibular plane angle according to Steiners analysis, the nature of the growth patterns, i.e., horizontal (HGP), Average (AGP) and vertical (VGP) growth pattern. Results: Individuals with loop patterns had a frequency of skeletal class I malocclusion, Whorl patterns with skeletal class II malocclusion, and Arch patterns with skeletal class III malocclusion. Consistent with the growth patterns, the whorl pattern was seen more prominently in the horizontal growth pattern, Arch pattern in the average growth pattern, and the loop pattern in the vertical growth pattern. Conclusion: Thus, the dermatoglyphics can be used as a screening tool for early prediction of skeletal malocclusion in a younger age group

Suspected human anthrax outbreak investigation in a tribal village of Koraput, India, 2021

Abstract Background Odisha is a state in India endemic to anthrax disease with frequent reports of suspected animal cases. A suspected outbreak of anthrax in humans was reported on 24 October 2021 at Tukum village in Koraput district of Odisha, India after a bullock was found dead and consumed by the locals on 17 October 2021. Methods This extended outbreak investigation was carried out through house‐to‐house active surveillance from 24 October to 2 November 2021 in the Koraput district. Eschar skin swabs from wounds were collected and processed at District Public Health Laboratory, Koraput, and analyzed in Indian Council of Medical Research‐Regional Medical Research Centre, Bhubaneswar for molecular confirmation. Samples from bone, soil, and dried meat were collected from the contaminated sites and were transported to Animal Diseases Research Institute, Cuttack for confirmation. Results Four suspected cases of human anthrax were identified who had handled and consumed dead bullock meat, among which one human had died later. The attack rate of the persons at risk in the village was calculated to be 1.23%. However, no Bacillus anthracis were identified in human swab samples when tested in real‐time polymerase chain reaction. Samples collected from contaminated sites were confirmed to have anthrax bacilli. Conclusion Investigation revealed that a suspected anthrax cluster outbreak was due to butchering/de‐skinning and consumption of the anthrax‐infected dead animal. The presence of bacilli in human samples could not be confirmed due to the intake of antibiotics before the collection of sample. This finding highlighted the importance of sample collection at a suitable time and a possible need for one health approach for better coordination among the different responsible departments

Strong electron-phonon coupling driven pseudogap modulation and density-wave fluctuations in a correlated polar metal

Abstract There is tremendous interest in employing collective excitations of the lattice, spin, charge, and orbitals to tune strongly correlated electronic phenomena. We report such an effect in a ruthenate, Ca3Ru2O7, where two phonons with strong electron-phonon coupling modulate the electronic pseudogap as well as mediate charge and spin density wave fluctuations. Combining temperature-dependent Raman spectroscopy with density functional theory reveals two phonons, B 2 P and B 2 M, that are strongly coupled to electrons and whose scattering intensities respectively dominate in the pseudogap versus the metallic phases. The B 2 P squeezes the octahedra along the out of plane c-axis, while the B 2 M elongates it, thus modulating the Ru 4d orbital splitting and the bandwidth of the in-plane electron hopping; Thus, B 2 P opens the pseudogap, while B 2 M closes it. Moreover, the B 2 phonons mediate incoherent charge and spin density wave fluctuations, as evidenced by changes in the background electronic Raman scattering that exhibit unique symmetry signatures. The polar order breaks inversion symmetry, enabling infrared activity of these phonons, paving the way for coherent light-driven control of electronic transport