Low-temperture electrostatic silicon-to-silicon seals using sputtered borosilicate glass

Silicon members are hermetically sealed to each other. Process produces no measurable deformation of silicon surfaces and is compatible with package designs of tight tolerance. Seals have been made with glass coatings in 10-mm to 20-mm thickness range without any prior annealing of coated silicon substrates

On the use of IR lidar and K(sub a)-band radar for observing cirrus clouds

Advances in lidar and radar technology have potential for providing new and better information on climate significant parameters of cirrus. Consequently, the NOAA Wave Propagation Lab. is commencing CLARET (Cloud Lidar And Radar Exploratory Test) to evaluate the promise of these new capabilities. Parameters under study include cloud particle size distribution, height of cloud bases, tops, and multiple layers, and cloud dynamics revealed through measurement of vertical motions. The first phase of CLARET is planned for Sept. 1989. The CO2 coherent Doppler lidar and the sensitive K sub a band radar hold promise for providing valuable information on cirrus that is beyond the grasp of current visible lidars

Reducing Hopelessness in Patients with Parkinson’s Disease: Educational Intervention

Reducing Hopelessness in Patients with Parkinson’s Disease: Educational Intervention BACKGROUND: Parkinson’s disease (PD), features several non-motor manifestations, including cognitive dysfunction, which impacts patients and their families. Depression, hopelessness, and anxiety are all prevalent in the psychiatric conditions of PD. In fact, at least 50% of those diagnosed with PD will experience some sort of depression, hopelessness, or anxiety disorder after diagnosis (Ray & Agarwal, 2020). The specific purpose of this project was to help patients with PD diagnosis feel less hopeless and more resilient when coping with their symptoms of PD. LOCAL PROBLEM: The project setting was a rural integrated health clinic. Patients with PD within the patient population are approximately 10 patients. These patients attend a PD support group meeting. The patients with this diagnosis who come to the clinic for their primary care have expressed concerns about their feelings of hopelessness and lack of education on the disease process and symptom management. METHODS: Levin’s Evidence-Based Practice Improvement Model was the guiding framework for this project. The selection of a questionnaire and the final process for educational implementation and clinical decision-making were determined using PDSA (plan-do-study-act) cycles. Pre-education and post-education were measured, as were the use of the tool. INTERVENTIONS: The project leader educated the group on the use of movement therapies and the Mediterranean diet to increase symptom control. The 20-question Beck’s Hopelessness scale was used for data collection to assess the symptoms of hopelessness and to track improvement after education on the given topics. A pre-and post-questionnaire was given to each participant and compared to receive the project results. RESULTS: A paired-sample t-test was used to determine whether there was a statistically significant mean difference between the pre-education hopelessness scores and post-education hopelessness scores. Participants had lower hopelessness scores after the education (M = 3.85, SD = 4.34) as opposed to before the education (M = 5.77, SD = 4.76), a statistically significant mean decrease of 1.92, 95% CI [0.68, 3.17], t(12) = 3.366, p = .006. CONCLUSIONS: Participants had lower hopelessness scores after the education as opposed to before the education, a statistically significant mean decrease. Educational interventions made this patient population feel heard and understood. There needs to be an increase in the PD support groups and the number of times they can meet per month. The support group needs more professionals willing to come in and speak with the group on symptom control

High temperature be panel development

Beryllium materials have been used for many aerospace applications over the years. Most of these applications have been fairly ambient environments. The possibility of fabricating beryllium panels for high temperature applications up to 1200 F is investigated. Joining alloys were reviewed, tested and evaluated for high temperature applications

Epstein-Barr virus infections and DNA hybridization studies in posttransplantation lymphoma and lymphoproliferative lesions: The role of primary infection

Fourteen patients who developed B cell lymphomas or lymphoproliferative lesions after kidney, liver, heart, or heart-lung transplantation in Pittsburgh during 1981-1983 had active infection with Epstein-Barr virus (EBV)of the primary (six patients), reactivated (seven patients), or chronic (one patient) type. In transplant patients without tumors, the incidence of EBV infection was 30% (39 of 128). Only three of these patients had primary infections. Thus the frequency of active infection was significantly higher in patients with tumors, and patients with primary infections were at greater risk of developing tumors. Five of 13 tumors tested contained EBV nuclear antigen (EBNA) and nine of 11 contained EBV genomes detected by DNA-DNA hybridization with BamHI K, BamHI W, or EcoRI B cloned probes. All EBNA-positive tumors, except one, were also positive by hybridization. Only one tumor was negative for both EBNA and EBV DNA. These data suggest that EBV plays an etiologic role in the development of these lesions. © 1985 by The University of Chicago

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy

Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts. Reduction or discontinuance of immunosuppression caused regression of the lesions, often without subsequent rejection of the grafts. Chemotherapy and irradiation were not valuable. The findings may influence policies about treating other kinds of post-transplantation neoplasms