Pengaruh Pendidikan Kesehatan Tentang Menopause Terhadap Perubahan Kualitas Hidup Perempuan Klimakterik

Physical and psychological changes that happen at the climacterium period would influence the quality of life in climacteric women. Therefore, the adaptation process is needed to overcome problems and changes during this period so that the quality of life of climacteric women could be increased. Lack of knowledge and access to information are major challenger that were faced by menopause women. One of efforts that can be done to improve their knowledge is through health education. This study aimed to identify the influence of health education about menopause towards the quality of live changes in climacteric women. The study used quasi experiment design with pretest and posttest nonequivalent control group. The location of this study was in Gamping Kidul Ambarketawang Village in December 2013 to April 2014. The total population is 271 people. Sample consisted of 44 people in the intervention group and 44 people in the control group. The intervention group received 4 times health education and small group discussion, as well as once relaxation and Yoga. Participants in control group received a booklet about menopause, signs and symptoms, nutrition during menopause period, and management of menopause. The quality of life was measured using WHOQOL-BREF. Analysis used paired t-test, independent samples t-test with α = 0.05. The mean scores of quality of life for intervention group were 51.0 (pretest) and 66.5 (posttest). The paired t-test showed that there was a significant difference of quality of life score before and after health education in the intervention group (t =14,436, p=0,001). However, there was no significant difference of quality of life in the control group (t=1,059, p= 0,0295). Based on this results, it can be concluded that health education program about menopause can increase quality of life of climacteric women

Protocol Study: Intervention Model of School Health Nursing for a Prevention of Adolescent Pregnancy

Adolescent pregnancy is a global concern. Pregnancies and births in adolescents bring them to get pregnancy complications. The interventions for pregnancy prevention in schools is one of the options that can be done. The purpose of the study is to determine the effect of school health nursing through the personal and social skills training for the primary prevention of adolescent pregnancy. This study is a quasi-experimental research design with nonequivalent (pretest and posttest) control group design. The outcome of the study was individual behavior change that includes confidence, a healthy dating, attitude in decision making, attitude on say no to premarital sex, and overcome the pressure of the group. This study will take place in high school A and Bin Yogyakarta that was selected based on purposive sampling. The study will be held from January to September 2016. At the intervention group, before the intervention, school nurses must first undergo a personal and social skills training. In addition, the school nurses are also trained to be a facilitator for adolescents. The school nurses will then retrain personal and social skills for adolescents in schools through theintervention of school health nursing for six months, while the control group will be given routine reproductive health education. If the school health nursing is effective, it will prevent adolescent pregnancy. This model can then be used widely in schools as an intervention for the prevention of adolescent pregnancy and the improvement of the quality of teenagers’ life. Keywords: Adolescent pregnancy, Adolescent pregnancy prevention, Health education, School health nursing, School nurs

Pemodelan Pelepasan in Vitro Tablet Floating Teofilin Dengan Program Ddsolver

The dissolution is an important element in drug development is mainly related to the absorption and bioavailability. The aim of this study was to determine in vitro dissolution study of theophylline floating tablet release kinetics model. The floating tablets were prepared by a wet granulation method with HPMC K4M CR, NaHCO3, lactose, and magnesium stearate as excipients. The result showed that the theophylline floating tablets had a weight uniformity (CV=1.93%), good hardness (8.4 kg), and low friability (0.05%). Dissolution data were evaluated using DDSolver conducted by 1). Statistical parameters: R2adjusted, mean square error (MSE), weighted sum of squares (WSS), akaike information criterion (AIC), model selection criterion (MSC); 2). Visual goodness of fit (GOF). The results showed that theophylline floating tablets release kinetics followed the Weibull equation. The dissolution curve is exponential shape and theophylline release occurs through a diffusion mechanism. Key words: floating tablet of theophylline, DDSolver, modeling of drug release

Performativitas Gender Dalam Film the Kids Are All Right Karya Lisa Cholodenko

Konsep heteronormativitas tidak memberikan ruang dan toleransi terhadap bentuk gender-gender lain kecuali laki-laki dan perempuan dan heteroseksual dianggap sebagai hubungan yang paling alamiah. Judith Butler, seorang pasca strukturalis, menolak dualisme gender tersebut yang secara sosial sangat sulit ditinggalkan. Film The Kids Are All Right karya Lisa Cholodenko ini mencoba keluar dari nilai-nilai heteronormatif tersebut dengan menampilkan pasangan lesbian yang telah berkeluarga lengkap dengan kehadiran anak-anak.Tujuan dari penelitian ini adalah untuk mengetahui strategi pembuat film dalam melakukan naturalisasi pasangan lesbian dalam konteks sosial keluarga dan mengungkap nilai-nilai dalam kultur dominan (heteronormatif) yang tidak bisa dilepaskan oleh film ini. Penelitian ini menggunakan pendekatan kualitatif dengan analisis semiotika model Roland Barthes melalui tahapan analisis sintagmatik dan paradigmatik dengan menggunakan lima kode pokok pembacaan teks. Strategi film dalam melakukan naturalisasi dengan menunjukkan bahwa pasangan homoseksual (lesbian) bisa memiliki anak sendiri, anak-anak yang diasuh oleh pasangan lesbian bisa berprestasi dan mempunyai tumbuh kembang yang baik, ikatan emosional anak-anak dengan orang tua maupun antar individu lesbian ketika sedang berkonflik (ditunjukkan melalui ekspresi menangis, marah, dan kecewa), adegan-adegan romantic relationship pasangan lesbian (berciuman, berpelukan, bergandengan tangan, dan bercinta), adanya transformasi nilai-nilai sosial dari orang tua ke anak-anak, dan orientasi seksual orang tuanya tidak mempengaruhi orientasi seksual anak-anaknya (walaupun masih menunjukkan adanya melancholic heterosexuality). Kecenderungan heteronormativitas terletak pada konstruksi praktek sosial dan kategori gender yang sifatnya tidak hanya dikotomis tetapi juga hirarkis melalui hadirnya simbol butch (dominasi maskulin)dan femme (peran domestik feminin). Film ini juga menunjukkan resistensi terhadap heteronormativitas dengan menampilkan kategori gender dan seksualitas yang cair. Performativitas gender disini adalah sesuatu yang kompleks karena bukan hanya sekadar imitasi bagaimana gender yang seharusnya ditampilkan oleh tokoh-tokoh dalam film, tetapi bukan USAha untuk menghindari pengulangan terhadap model heteronormativitas tentang bagaimana laki-laki dan perempuan seharusnya

Potensi Ekstrak Kapang Endofit Asal Rimpang Kunyit Sebagai Antimalaria Dan Antioksidan

Malaria infection is still a public health problem, especially in developing countries, including Indonesia. Malaria infection is usually accompanied by increased free radicals in the body of the patient. This situation will cause decreasing the immune system of the patient. Explorating of new drugs that have antimalarial and also antioxidant activity is very important. Therefore, this study aims to determine in vitro antimalarial and antioxidant activity of endophytic fungi extract origin turmeric from Sukabumi. This study begins with fermentation process of endophytic fungi on the broth medium and ethyl acetate was used to extract the filtrat to gain the test extracts. Heme polymerization inhibition and free radical DPPH scavenging method were used to antimalarial and antioxidant in vitro assay respectively. The results showed that 18 isolates of endophytic fungi have antimalarial activity and one isolate inactive and also all isolates have antioxidant activity. Smi.Cl.6F isolate was the most active isolate on the antimalarial and antioxidant assay with IC50 value of each assay were 1.93 mg/mL and 32.28 mg/L respectively. Therefore, Smi.Cl.6F isolates potentially be used as new antimalarial drugs

Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota)

Compared to the higher fungi (Dikarya), taxonomic and evolutionary studies on the basal clades of fungi are fewer in number. Thus, the generic boundaries and higher ranks in the basal clades of fungi are poorly known. Recent DNA based taxonomic studies have provided reliable and accurate information. It is therefore necessary to compile all available information since basal clades genera lack updated checklists or outlines. Recently, Tedersoo et al. (MycoKeys 13:1--20, 2016) accepted Aphelidiomycota and Rozellomycota in Fungal clade. Thus, we regard both these phyla as members in Kingdom Fungi. We accept 16 phyla in basal clades viz. Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota. Thus, 611 genera in 153 families, 43 orders and 18 classes are provided with details of classification, synonyms, life modes, distribution, recent literature and genomic data. Moreover, Catenariaceae Couch is proposed to be conserved, Cladochytriales Mozl.-Standr. is emended and the family Nephridiophagaceae is introduced

Protocol Study: Intervention Model of School Health Nursing for A Prevention of Adolescent Pregnancy

Adolescent pregnancy is a global concern. Pregnancies and births in adolescents bring them to get pregnancy complications. The interventions for pregnancy prevention in schools is one of the options that can be done. The purpose of the study is to determine the effect of school health nursing through the personal and social skills training for the primary prevention of adolescent pregnancy. This study is a quasi-experimental research design with nonequivalent (pretest and posttest) control group design. The outcome of the study was individual behavior change that includes confidence, a healthy dating, attitude in decision making, attitude on say no to premarital sex, and overcome the pressure of the group. This study will take place in high school A and Bin Yogyakarta that was selected based on purposive sampling. The study will be held from January to September 2016. At the intervention group, before the intervention, school nurses must first undergo a personal and social skills training. In addition, the school nurses are also trained to be a facilitator for adolescents. The school nurses will then retrain personal and social skills for adolescents in schools through theintervention of school health nursing for six months, while the control group will be given routine reproductive health education. If the school health nursing is effective, it will prevent adolescent pregnancy. This model can then be used widely in schools as an intervention for the prevention of adolescent pregnancy and the improvement of the quality of teenagers' life. Keywords: Adolescent pregnancy, Adolescent pregnancy prevention, Health education, School health nursing, School nurs