827 research outputs found
Containerless preparation of advanced optical glasses: Experiment 77F095
Containerless processing of optical glasses was studied in preparation for space shuttle MEA flight experiments. Ground based investigation, experiment/hardware coordination activities and development of flight experiment and sample characterization plans were investigated. In the ground based investigation over 100 candidate glass materials for space processing were screened and promising compositions were identified. The system of Nb2O5-TiO2-CaO was found to be very rich with containerless glass compositions and as extensive number of the oxides combinations were tried resulting in a glass formation ternary phase diagram. The frequent occurrence of glass formation by containerless processing among the compositions for which no glass formations were previously reported indicated the possibility and an advantage of containerless processing in a terrestrial environment
Automatic orienting towards face-like stimuli in early childhood
Newborn infants orient preferentially toward face-like or “protoface” stimuli and recent studies suggest similar reflexive orienting responses in adults. Little is known, however, about the operation of this mechanism in childhood. An attentional-cueing procedure was therefore developed to investigate protoface orienting in early childhood. Consistent with the extant literature, 5- to 6-year-old children (n = 25) exhibited orienting toward face-like stimuli; they responded faster when target location was cued by the appearance of a protoface stimulus than when location was cued by matched control patterns. The potential of this procedure to investigate the development of typical and atypical social perception is discussed
Effects of Frontal Transcranial Direct Current Stimulation on Emotional State and Processing in Healthy Humans
The prefrontal cortex is involved in mood and emotional processing. In patients suffering from depression, the left dorsolateral prefrontal cortex (DLPFC) is hypoactive, while activity of the right DLPFC is enhanced. Counterbalancing these pathological excitability alterations by repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) improves mood in these patients. In healthy subjects, however, rTMS of the same areas has no major effect, and the effects of tDCS are mixed. We aimed to evaluate the effects of prefrontal tDCS on emotion and emotion-related cognitive processing in healthy humans. In a first study, we administered excitability-enhancing anodal, excitability-diminishing cathodal, and placebo tDCS to the left DLPFC, combined with antagonistic stimulation of the right frontopolar cortex, and tested acute emotional changes by an adjective checklist. Subjective emotions were not influenced by tDCS. Emotional face identification, however, which was explored in a second experiment, was subtly improved by a tDCS-driven excitability modulation of the prefrontal cortex, markedly by anodal tDCS of the left DLPFC for positive emotional content. We conclude that tDCS of the prefrontal cortex improves emotion processing in healthy subjects, but does not influence subjective emotional state
Modular DSLs for flexible analysis: An e-Motions reimplementation of Palladio
We address some of the limitations for extending and validating MDE-based implementations of NFP analysis tools by presenting a modular, model-based partial reimplementation of one well-known analysis framework, namely the Palladio Architecture Simulator. We specify the key DSLs from Palladio in the e-Motions system, describing the basic simulation semantics as a set of graph transformation rules. Di erent properties to be analysed are then encoded as separate, parametrised DSLs, independent of the de nition of Palladio. These can then be composed with the base Palladio DSL to generate speci c simulation environments. Models created in the Palladio IDE can be fed directly into this simulation environment for analysis. We demonstrate two main benefits of our approach: 1) The semantics of the simulation and the nonfunctional properties to be analysed are made explicit in the respective DSL speci cations, and 2) because of the compositional de nition, we can add de nitions of new non-functional properties and their analyses.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Using Performance Forecasting to Accelerate Elasticity
Cloud computing facilitates dynamic resource provisioning. The automation of resource management, known as elasticity, has been subject to much research. In this context, monitoring of a running service plays a crucial role, and adjustments are made when certain thresholds are crossed. On such occasions, it is common practice to simply add or remove resources. In this paper we investigate how we can predict the performance of a service to dynamically adjust allocated resources based on predictions. In other words, instead of “repairing” because a threshold has been crossed, we attempt to stay ahead and allocate an optimized amount of resources in advance. To do so, we need to have accurate predictive models that are based on workloads. We present our approach, based on the Universal Scalability Law, and discuss initial experiments
Similarities in the architecture of the active sites of Ni-hydrogenases and Fe-hydrogenases detected by means of infrared spectroscopy
The diagnosis of mental disorders: the problem of reification
A pressing need for interrater reliability in the diagnosis of mental disorders
emerged during the mid-twentieth century, prompted in part by
the development of diverse new treatments. The Diagnostic and Statistical
Manual of Mental Disorders (DSM), third edition answered this need
by introducing operationalized diagnostic criteria that were field-tested
for interrater reliability. Unfortunately, the focus on reliability came at a
time when the scientific understanding of mental disorders was embryonic
and could not yield valid disease definitions. Based on accreting
problems with the current DSM-fourth edition (DSM-IV) classification,
it is apparent that validity will not be achieved simply by refining
criteria for existing disorders or by the addition of new disorders. Yet
DSM-IV diagnostic criteria dominate thinking about mental disorders
in clinical practice, research, treatment development, and law. As a result,
the modernDSMsystem, intended to create a shared language, also
creates epistemic blinders that impede progress toward valid diagnoses.
Insights that are beginning to emerge from psychology, neuroscience,
and genetics suggest possible strategies for moving forward
Similarities in the architecture of the active sites of Ni-hydrogenases and Fe-hydrogenases detected by means of infrared spectroscopy
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