19,203 research outputs found
Simultaneous imaging of a lacZ-marked tumor and microvasculature morphology in vivo by dual-wavelength photoacoustic microscopy
Photoacoustic molecular imaging, combined with the reporter-gene technique, can provide a valuable tool for cancer research. The expression of the lacZ reporter gene can be imaged using photoacoustic imaging following the injection of X-gal, a colorimetric assay for the lacZ-encoded enzyme β-galactosidase. Dual-wavelength photoacoustic microscopy was used to non-invasively image the detailed morphology of a lacZ-marked 9L gliosarcoma and its surrounding microvasculature simultaneously in vivo, with a superior resolution on the order of 10 μm. Tumor-feeding vessels were found, and the expression level of lacZ in tumor was estimated. With future development of new absorption-enhancing reporter-gene systems, we anticipate this strategy can lead to a better understanding of the role of tumor metabolism in cancer initiation, progression, and metastasis, and in its response to therapy
Microwave intermodulation distortion of MgB2 thin films
The two tone intermodulation arising in MgB2 thin films deposited in-situ by
planar magnetron sputtering on sapphire substrates is studied. Samples are
characterised using an open-ended dielectric puck resonator operating at 8.8
GHz. The experimental results show that the third order products increase with
the two-tone input power with a slope ranging between 1.5 and 2.3. The
behaviour can be understood introducing a mechanism of vortex penetration in
grain boundaries as the most plausible source of non linearities in these
films. This assumption is confirmed by the analysis of the field dependence of
the surface resistance, that show a linear behaviour at all temperatures under
test.Comment: 13 pages, 3 figures; to be published in Appl. Phys. Let
CMBR Constraint on a Modified Chaplygin Gas Model
In this paper, a modified Chaplygin gas model of unifying dark energy and
dark matter with exotic equation of state
which can also explain the recent accelerated expansion of the universe is
investigated by the means of constraining the location of the peak of the CMBR
spectrum. We find that the result of CMBR measurements does not exclude the
nonzero value of parameter , but allows it in the range .Comment: 4 pages, 3 figure
Magnons in Ferromagnetic Metallic Manganites
Ferromagnetic (FM) manganites, a group of likely half-metallic oxides, are of
special interest not only because they are a testing ground of the classical
doubleexchange interaction mechanism for the colossal magnetoresistance, but
also because they exhibit an extraordinary arena of emergent phenomena. These
emergent phenomena are related to the complexity associated with strong
interplay between charge, spin, orbital, and lattice. In this review, we focus
on the use of inelastic neutron scattering to study the spin dynamics, mainly
the magnon excitations in this class of FM metallic materials. In particular,
we discussed the unusual magnon softening and damping near the Brillouin zone
boundary in relatively narrow band compounds with strong Jahn-Teller lattice
distortion and charge/orbital correlations. The anomalous behaviors of magnons
in these compounds indicate the likelihood of cooperative excitations involving
spin, lattice, as well as orbital degrees of freedom.Comment: published in J. Phys.: Cond. Matt. 20 figure
Topological Effects caused by the Fractal Substrate on the Nonequilibrium Critical Behavior of the Ising Magnet
The nonequilibrium critical dynamics of the Ising magnet on a fractal
substrate, namely the Sierpinski carpet with Hausdorff dimension =1.7925,
has been studied within the short-time regime by means of Monte Carlo
simulations. The evolution of the physical observables was followed at
criticality, after both annealing ordered spin configurations (ground state)
and quenching disordered initial configurations (high temperature state), for
three segmentation steps of the fractal. The topological effects become evident
from the emergence of a logarithmic periodic oscillation superimposed to a
power law in the decay of the magnetization and its logarithmic derivative and
also from the dependence of the critical exponents on the segmentation step.
These oscillations are discussed in the framework of the discrete scale
invariance of the substrate and carefully characterized in order to determine
the critical temperature of the second-order phase transition and the critical
exponents corresponding to the short-time regime. The exponent of the
initial increase in the magnetization was also obtained and the results suggest
that it would be almost independent of the fractal dimension of the susbstrate,
provided that is close enough to d=2.Comment: 9 figures, 3 tables, 10 page
Photosynthetic characterization of a rolled leaf mutant of rice (Oryza sativa L.)
A new rolling leaf rice mutant was identified which showed an apparently straighter longitudinal shape normal transverse rolling characters at all developing stages. The chlorophyll contents per fresh weight of this mutant leaves were lower than those of wild-type. The electron transfer rate (ETR) and photochemical quenching (qP) were a little higher than those of wild-type. However, because of significant increase of non-photochemical quenching (NPQ), the maximal photosystem II (PSII) photochemistry (Fv/Fm) and the efficiency of excitation energy trapping by open PSII reaction centers in the light–adapted state (Fv’/Fm’) were lower than those of wild-type. Low temperature fluorescence analysis showed that rolling leaf mutant assigned more excited energy to photosystem I (PSI) than to PSII. The superoxide dismutase (SOD) content, soluble sugar content, proline content and malonaldehyde (MDA) content of the rolling leaf mutant were nearly 39.4, 91.2, 96.7 and 143.7% of those of wild-type, respectively. The great increase of MDA content suggests that membrane lipid system was damaged in rolling leaf mutant leaves. These results indicate that rolling leaf mutant decrease the efficiency of light utilization compared to the wild-type. This was because of the reduction of leaf area and chlorophyll contents, and the dissipation of more excitation energy as NPQ as a result of avoiding potential damage of membrane structure.Key words: Malonaldehyde (MDA), photosynthetic characterization, rice, rolling leaf mutant
Neutron Transfer reactions induced by 8Li on 9Be
Angular distributions for the elastic scattering of 8Li on 9Be and the
neutron transfer reactions 9Be(8Li,7Li)10Be and 9Be(8Li,9Li)8Be have been
measured with a 27 MeV 8Li radioactive nuclear beam. Spectroscopic factors for
8Li|n=9Li and 7Li|n=8Li bound systems were obtained from the comparison between
the experimental differential cross section and finite-range DWBA calculations
with the code FRESCO. The spectroscopic factors obtained are compared to shell
model calculations and to other experimental values from (d,p) reactions. Using
the present values for the spectroscopic factor, cross sections for the direct
neutron-capture reactions 7Li(n,g)8Li and 8Li(n,g)9Li were calculated in the
framework of a potential model.Comment: 24 pages, 8 Figures, submitted as regular article to PR
- …