Effect of stabilizer on flutter stability of truss girder suspension bridges

An aerodynamic optimization measure of the flutter stability of long-span suspension bridges with truss girder is presented in this paper. At first, the improvement of several kinds of central stabilizers and horizontal stabilizers on flutter stability is examined through series of section model and full aeroelastic model wind tunnel tests. Subsequently, the flutter derivatives of the truss girder with and without stabilizer are identified based on two degrees of freedom coupling free vibration method. Furthermore, based on the identified flutter derivatives, the critical flutter velocities of the truss girder section with and without stabilizer are analyzed through two dimensional flutter analysis method and the critical flutter velocities of the full bridge with and without stabilizer are analyzed through three dimensional method. Afterwards, the influence of each flutter derivative on the flutter stability of the truss girder is investigated. The results indicate that central upper stabilizer can effectively increase the critical flutter velocity of the truss girder. In contrast, the central lower stabilizer and horizontal stabilizer have less influence. Setting up central upper stabilizer leads to an obvious decrease in the value of the flutter derivatives A2* and H2*, while the flutter derivatives H1*, H4*, A1* and A3* are little influenced. The two dimensional and three dimensional flutter analysis results agree well with the sectional model and full model wind tunnel test results respectively

Constraining Dark Energy From Splitting Angle Statistic of Strong Gravitational Lenses

Utilizing the CLASS statistical sample, we investigate the constraint of the splitting angle statistic of strong gravitational lenses(SGL) on the equation-of-state parameter $w=p/\rho$ of the dark energy in the flat cold dark matter cosmology. Through the comoving number density of dark halos described by Press-Schechter theory, dark energy affects the efficiency with which dark-matter concentrations produce strong lensing signals. The constraints on both constant $w$ and time-varying $w(z)=w_0+w_az/(1+z)$ from the SGL splitting angle statistic are consistently obtained by adopting a two model combined mechanism of dark halo density profile matched at the mass scale $M_c$. Our main observations are: (a) the resulting model parameter $M_c$ is found to be $M_c \sim 1.4$ for both constant $w$ and time-varying $w(z)$, which is larger than $M_c \sim 1$ obtained in literatures; (b) the fitting results for the constant $w$ are found to be $w =-0.89^{+0.49}_{-0.26}$ and $w =-0.94^{+0.57}_{-0.16}$ for the source redshift distributions of the Gaussian models $g(z_s)$ and $g^c(z_s)$ respectively, which are consistent with the $\Lambda \rm CDM$ at 95% C.L; (c) the time-varying $w(z)$ is found to be for $\sigma_8 = 0.74$: $(M_c; w_0, w_a)=(1.36; -0.92, -1.31)$ and $(M_c; w_0, w_a)=(1.38; -0.89, -1.21)$ for $g(z_s)$ and $g^c(z_s)$ respectively.Comment: 30 pages, 10 figures, references added, improved version to be published in Ap

Thyroid dose assessments due to inhalation of 131I for nuclear medicine workers

BackgroundIn general, medical staff who work in nuclear medicine should be entirely safe in their professional environment. Nevertheless, we already know that the working environment of the nuclear medicine staff is not completely safe due to the handling of high amounts of radionuclides for diagnostic and therapy applications, which is especially relevant for 131I (as a non-sealed source).PurposeThe goal of this study was to assess the inhaled 131I thyroid dose in nuclear medicine workers and to introduce a simple method for internal exposure monitoring.MethodsUsing 2-IN*2-in NaI (Tl) scintillation spectrometer and its supporting software (InSpector Maintenance Utility and Genie 2000), from 2019 to 2021, internal thyroid irradiation monitoring, an internal thyroid irradiation monitoring investi A NaI (Tl) scintillation spectrometer and its sugation was carried out for 3 consecutive years, between 2019 and 2021, in staff members of nuclear medicine departments engaged with iodine therapy.Results131I activity was found highest in the thyroid of nuclear medicine workers involved with the manual packaging and delivery of the radioisotope, while it was not detected in staff members involved with the automatic packaging and drug delivery. The activity range was found to be 30.00 ± 6.60–6070.00 ± 1335.40 Bq for the exposed personnel, and the estimated dose was 0.05–6.77 mSv. In 2021, three workers had an annual equivalent dose above 5 mSv.ConclusionBy monitoring the thyroid 131I in staff members of the nuclear medicine department, it was found that there are 131I internal occupational exposure risks. The best solution is automatic packaging and drug delivery

Janus monolayers of transition metal dichalcogenides.

Structural symmetry-breaking plays a crucial role in determining the electronic band structures of two-dimensional materials. Tremendous efforts have been devoted to breaking the in-plane symmetry of graphene with electric fields on AB-stacked bilayers or stacked van der Waals heterostructures. In contrast, transition metal dichalcogenide monolayers are semiconductors with intrinsic in-plane asymmetry, leading to direct electronic bandgaps, distinctive optical properties and great potential in optoelectronics. Apart from their in-plane inversion asymmetry, an additional degree of freedom allowing spin manipulation can be induced by breaking the out-of-plane mirror symmetry with external electric fields or, as theoretically proposed, with an asymmetric out-of-plane structural configuration. Here, we report a synthetic strategy to grow Janus monolayers of transition metal dichalcogenides breaking the out-of-plane structural symmetry. In particular, based on a MoS2 monolayer, we fully replace the top-layer S with Se atoms. We confirm the Janus structure of MoSSe directly by means of scanning transmission electron microscopy and energy-dependent X-ray photoelectron spectroscopy, and prove the existence of vertical dipoles by second harmonic generation and piezoresponse force microscopy measurements

Construction of a cross-species cell landscape at single-cell level.

Individual cells are basic units of life. Despite extensive efforts to characterize the cellular heterogeneity of different organisms, cross-species comparisons of landscape dynamics have not been achieved. Here, we applied single-cell RNA sequencing (scRNA-seq) to map organism-level cell landscapes at multiple life stages for mice, zebrafish and Drosophila. By integrating the comprehensive dataset of > 2.6 million single cells, we constructed a cross-species cell landscape and identified signatures and common pathways that changed throughout the life span. We identified structural inflammation and mitochondrial dysfunction as the most common hallmarks of organism aging, and found that pharmacological activation of mitochondrial metabolism alleviated aging phenotypes in mice. The cross-species cell landscape with other published datasets were stored in an integrated online portal-Cell Landscape. Our work provides a valuable resource for studying lineage development, maturation and aging

Effects of Cold Rolling and Annealing Prior to Dealloying on the Microstructure of Nanoporous Gold

The properties of nanoporous gold (NPG) were known to be dependent on the microstructure of NPG. In this study, the effects of cold rolling and annealing of the original Ag0.7Au0.3 alloy on the microstructure of NPG produced by dealloying under free corrosion condition were investigated. Ag0.7Au0.3 alloy samples were cold-rolled to different strain levels/thickness reductions up to 98% and annealed at 900 °C for 3 h before dealloying. It was found that cold rolling and annealing of the original alloy can lead to reduced ligament and pore sizes of NPG. Moreover, post-deformation annealing of the original alloy was found to facilitate the formation of a homogeneous and continuous NPG structure. The minima of pore and ligament sizes (both being ~8 nm) with uniform distribution were obtained in the annealed sample with a thickness reduction of 60% for a dealloying time of 7 h. The present study indicated the significant effect of a pre-dealloying treatment of the original alloy (by plastic deformation and annealing) on the formation and optimization of the NPG microstructure produced by dealloying

Investigation effect of wettability and heterogeneity in water flooding and on microscopic residual oil distribution in tight sandstone cores with NMR technique

In order to explore the effect of wettability and pore throat heterogeneity on oil recovery efficiency in porous media, physical simulation experiment and nuclear magnetic resonance (NMR) measurements were conducted to investigate how crude oil residing in different sized pores are recovered by water flooding. Experimental results indicate that the recovery factor of water flooding is governed by spontaneous imbibition and also pore throat heterogeneity. It is found that intermediate wetting cores lead to the highest final recovery factor in comparison with water wet cores and weak oil wet cores, and the recovery oil difference in clay micro pore is mainly because of the wettability, the difference in medium pore and large pore is affected by pore throat heterogeneity. Water wet core has a lower recovery factor in medium and large pore due to its poor heterogeneity, in spite of the spontaneous imbibition effect is very satisfying. Intermediate wetting cores has significant result in different sized pore and throat, the difference in medium pore and large pore is affected by pore throat heterogeneity

An enterovirus A71 virus-like particle with replaced loops confers partial cross-protection in mice

Enterovirus A71 (EV-A71), coxsackievirus A16 (CV-A16), and CV-A10 belong to the main prevailing types causing hand-foot-and-mouth disease. Since EV-A71 monovalent vaccine does not confer cross-protection, developing a multivalent vaccine is essential. In this study, a trivalent chimeric virus-like particle of EV-A71 (EV-A71-VLPCHI3) was constructed based on EV-A71-VLP backbone by replacing the corresponding surface loops with CV-A16 VP1 G-H, CV-A10 VP1 B-C and E-F loops, which are critical for immunogenic neutralization. The baculovirus-insect cell expression system was employed for EV-A71-VLPCHI3 production. EV-A71-VLPCHI3 was purified by sucrose density gradient and observed by transmission electron microscopy. The immunogenicity and protective efficacy of EV-A71-VLPCHI3 were evaluated in mice. Our results revealed that EV-A71-VLPCHI3 had a similar morphology to inactivated EV-A71 particles and could induce specific IgG antibodies against EV-A71, CV-A16 and CV-A10 in mice. More importantly, EV-A71-VLPCHI3 enhanced cross-reactive protection against CV-A16 and CV-A10, by 20 % and 40 %, compared to inactivated EV-A71 counterparts, respectively. In conclusion, the successful construction of EV-A71-VLPCHI3 suggested that loop-dependent heterologous protection could be transferred by loops replacement on the surface of viral capsid. This strategy may also supplement the development of multivalent vaccines against other infectious viral diseases