3,438 research outputs found

    Uppercase and lowercase computer printout increases readability

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    Print chain of 120 characters facilitates production of computer printout in both uppercase and lowercase characters. Although the output speed is reduced, the use of the print chain increases the computer printout readability

    Contrasting the capabilities of building energy performance simulation programs

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    For the past 50 years, a wide variety of building energy simulation programs have been developed, enhanced and are in use throughout the building energy community. This paper is an overview of a report, which provides up-to-date comparison of the features and capabilities of twenty major building energy simulation programs. The comparison is based on information provided by the program developers in the following categories: general modeling features; zone loads; building envelope and daylighting and solar; infiltration, ventilation and multizone airflow; renewable energy systems; electrical systems and equipment; HVAC systems; HVAC equipment; environmental emissions; economic evaluation; climate data availability, results reporting; validation; and user interface, links to other programs, and availability

    Exploring Predictors of Healing from an Expressive Writing Intervention About Heterosexism and Why LGBTQ+ Clients Might Withhold from their Therapists

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    Heterosexism is a cultural system that impacts LGBTQ+ individuals internally, interpersonally, institutionally, and structurally. Exposure to these different levels of heterosexism, whether enacted overtly, covertly, intentionally, or unintentionally, contributes to the well-documented and disproportionate negative mental health outcomes experienced by the LGBTQ+ community (National Academies of Sciences, Engineering, and Medicine [NASEM], 2020). Subsequently, LGBTQ+ individuals seek out professional mental health services at higher rates than cisgender and heterosexual populations, though access to therapeutic care that addresses sexual minority specific stressors, such as experiencing heterosexism directly, is limited (Williams & Fish, 2020). The current study is a secondary analysis of a larger study of an online expressive writing intervention designed to promote healing for LGBTQ+ individuals who have experienced heterosexism. This study examined if and how characteristics of the heterosexist event that participants wrote about predicted healing outcomes. Specifically, I examined if and how the duration, recency, and severity of the distress during the heterosexist experience predicted changes in depressive symptoms and event-related stress among participants from Baseline, Day 4, and at two-month Follow Up as well as participants’ perceptions of change. In addition, I examined if and how participants’ prior disclosure (or non-disclosure) of heterosexist experiences to a therapist was a predictor of those healing outcomes. And, finally, I conducted a grounded theory analysis to understand the reasons why LGBTQ+ clients may or may not disclose their experiences to their therapists. This study can add nuance to the literature in understanding who benefits most from an online, free expressive writing intervention about heterosexism. The results also provide useful information for therapists seeking to foster a safe and comfortable environment for LGBTQ+ clients to discuss their heterosexist experiences

    Dear Wife : the Civil War letters of Chester K. Leach

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    Occasional paper (University of Vermont. Center for Research on Vermont) ; no. 20

    Litigious Vermonters : court records to 1825

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    Occasional paper (University of Vermont. Center for Research on Vermont) ; no. 2

    Glycosylation of cyclooxygenase-2 (COX-2) influences the migratory and invasive potential of cells

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    Prostaglandins are bioactive lipids involved in many physiological functions such as maintenance of the cardiovascular, immune, renal, and central nervous systems. They also play a role in certain diseases like arthritis, cancer, and Alzheimer’s. Cyclooxygenase-2 (COX-2) is the enzyme that catalyzes the initial rate-limiting step in the pathway that converts arachidonic acid to prostaglandins. COX-2 exists as two glycoforms with the molecular weights of 72 and 74 kDa, the latter resulting from the addition of a high mannose chain to the Asn580 residue ~50% of the time. The over-expression of COX-2 is believed to be linked to cancer progression and specifically appears to promote the metastatic phenotype. The objective of this study is to determine the effect of the variable glycosylation of COX-2 at Asn580 on the migratory and invasive potential of cells. COS-1 cells and the breast cancer cell line MCF7 were first transfected with either the wild type or Asn580-mutant human COX-2 gene. Boyden chambers were used to determine the ability of transfected cells to migrate through the membrane, approximately 5x104 cells were plated onto the chambers, and cells were incubated for 16-18 h. Cells were then fixed, stained, visualized and counted. In a previous study, our lab showed that COS-1 cells transfected with the Asn580-mutant COX-2 gene migrated faster through the membrane. In this current study, COS-1 cells transfected with the Asn580-mutant COX-2 gene also had a greater invasive potential; however, MCF7 cells transfected with the wild-type human COX-2 gene migrated faster and also had a greater tendency to invade. The results indicate that the ability of this additional or the lack of glycosylation of COX-2 at Asn580 to either enhance or inhibit the migratory and invasive potential of cells depends greatly on cell type. To confirm this, future studies will be carried out to determine the effect of COX-2 glycosylation on the invasive and the migratory potential of PC-3 and T-47D cancer cell lines.https://scholar.dominican.edu/natural-sciences-and-mathematics-faculty-research-posters/1000/thumbnail.jp

    Potassium corrosion test loop development - Purification, analysis and handling of sodium and potassium Topical report no. 4

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    Corrosion test loop, and purification, analysis, and handling of sodium and potassiu

    Nanosecond laser texturing for high friction applications

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    AbstractA nanosecond pulsed Nd:YAG fibre laser with wavelength of 1064nm was used to texture several different steels, including grade 304 stainless steel, grade 316 stainless steel, Cr–Mo–Al ‘nitriding’ steel and low alloy carbon steel, in order to generate surfaces with a high static friction coefficient. Such surfaces have applications, for example, in large engines to reduce the tightening forces required for a joint or to secure precision fittings easily. For the generation of high friction textures, a hexagonal arrangement of laser pulses was used with various pulse overlaps and pulse energies. Friction testing of the samples suggests that the pulse energy should be high (around 0.8mJ) and the laser pulse overlap should be higher than 50% in order to achieve a static friction coefficient of more than 0.5. It was also noted that laser processing increases the surface hardness of samples which appears to correlate with the increase in friction. Energy-Dispersive X-ray spectroscopy (EDX) measurements indicate that this hardness is caused by the formation of hard metal-oxides at the material surface
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