Approximate biflatness and Johnson pseudo-contractibility of some Banach algebras

summary:We study the structure of Lipschitz algebras under the notions of approximate biflatness and Johnson pseudo-contractibility. We show that for a compact metric space $X$, the Lipschitz algebras ${\rm Lip}_{\alpha}(X)$ and ${\rm lip}_{\alpha}(X)$ are approximately biflat if and only if $X$ is finite, provided that $0<\alpha<1$. We give a necessary and sufficient condition that a vector-valued Lipschitz algebras is Johnson pseudo-contractible. We also show that some triangular Banach algebras are not approximately biflat

Effects of Rejuvenators on High-RAP Mixtures Based on Laboratory Tests of Asphalt Concrete Mixtures and Fine Aggregate Matrix Mixtures

Although the linear viscoelastic stiffness, fracture characteristics, and permanent deformation behavior of AC mixtures can be determined through experiments, it is generally time-consuming and expensive to reach statistically repeatable results. Thus, it is attractive to pursue alternative methods that are cheaper, faster, and repeatable in order to efficiently evaluate and predict asphalt mixtures’ core mechanical characteristics (such as stiffness, fatigue, and plastic deformation)

Barriers and Enablers for Industry 4.0 in SMEs: A Combined Integration Framework

Although Industry 4.0 was introduced a decade ago, many small and medium-sized enterprises (SMEs) still have not adopted several technologies. Therefore, integrating SMEs along horizontal, vertical, and end-to-end engineering dimensions remains challenging. Due to the importance of SMEs for industrial value chains, understanding SMEs' barriers and respective enablers for Industry 4.0 integration is vital. Applying a multiple case study approach, this paper investigates their experience in Industry 4.0 through technological, organizational, and environmental factors. We aggregate the barriers and respective enablers to Industry 4.0 into an integration framework, which helps to understand Industry 4.0 in SMEs from a broader viewpoint inside these firms, upstream and downstream supply chains, and beyond manufacturing. The findings show that the success of Industry 4.0 integration is more oriented toward operational benefits than strategic advantages and depends upon how these technologies are integrated with various stakeholders across the supply chain, such as original equipment manufacturers, R&D agencies, or sub-suppliers

IS THE LAST PLANNER SYSTEM APPLICABLE TO DESIGN? A CASE STUDY

ABSTRACT The Last Planner TM system has been successfully implemented in construction to increase the reliability of planning, improve production performance, and create a predictable workflow. However, some practitioners question the function of the Last Planner TM system during design especially that design processes involve iterations and circular chains of interaction between different parties. The purpose of this paper is to report on research comprising the application of Last Planner TM system in design. The paper describes the developments and adjustments introduced to the Last Planner TM system to better suit design processes on a health care project in North America. Novel standardized planning practices used on the project are reported and analyzed. The study findings suggest that the Last Planner TM system principles account for both deliberative and situated action models. On one hand, deliberative planning 4 takes place at the master and phase scheduling level where a premeditated rigid course of action is undertaken in setting milestones and identifying handoffs. On the other hand, situated planning is performed at the lookahead planning and weekly work planning stages where planning takes into account changes in the environment and the uncertainty affecting inputs, processes, and outputs of design activities. KEY WORDS Lean design, last planner tm system, lookahead planning, production control, lean construction

Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant Bacillus strain

Introduction: The bacterial enzyme has gained more attention in therapeutic application because of the higher substrate specificity and longer half-life. L-asparaginase is an important enzyme with known antineoplastic effect against acute lymphoblastic leukemia (ALL). Methods: Novel L-asparaginase genes were identified from a locally isolated halo-thermotolerant Bacillus strain and the recombinant enzymes were overexpressed in modified E. coli strains, OrigamiTM B and BL21. In addition, the biochemical properties of the purified enzymes were characterized, and the enzyme activity was evaluated at different temperatures, pH, and substrate concentrations. Results: The concentration of pure soluble enzyme obtained from Origami strain was ~30 mg/L of bacterial culture, which indicates the significant improvement compared to L-asparaginase produced by E. coli BL21 strain. The catalytic activity assay on the identified L-asparaginases (ansA1 and ansA3 genes) from Bacillus sp. SL-1 demonstrated that only ansA1 gene codes an active and stable homologue (ASPase A1) with high substrate affinity toward L-asparagine. The Kcat and Km values for the purified ASPase A1 enzyme were 23.96s-1 and 10.66 µM, respectively. In addition, the recombinant ASPase A1 enzyme from Bacillus sp. SL-1 possessed higher specificity to L-asparagine than L-glutamine. The ASPase A1 enzyme was highly thermostable and resistant to the wide range of pH 4.5�10. Conclusion: The biochemical properties of the novel ASPase A1 derived from Bacillus sp. SL-l indicated a great potential for the identified enzyme in pharmaceutical and industrial applications. © 2019 The Author(s)

Effect of increasing age on percutaneous coronary intervention vs coronary artery bypass grafting in older adults with unprotected left main coronary artery disease: A meta-analysis and meta-regression

Background: Older adults (≥70-year-old) are under-represented in the published data pertaining to unprotected left main coronary artery disease (ULMCAD).Hypothesis: Percutaneous coronary intervention (PCI) might be comparable to coronary artery bypass grafting (CABG) for revascularization of ULMCAD.Methods: We compared PCI versus CABG in older adults with ULMCAD with an aggregate data meta-analyses (4880 patients) of clinical outcomes [all-cause mortality, myocardial infarction (MI), repeat revascularization, stroke and major adverse cardiac and cerebrovascular events(MACCE)] at 30 days, 12-24 months & ≥36 months in patients with mean age ≥70 years and ULMCAD. A meta-regression analysis evaluated the effect of age on mortality after PCI. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using random-effects model.Results: All-cause mortality between PCI and CABG was comparable at 30-days (OR0.77, 95% CI 0.42- 1.41) and 12-24-months (OR 1.22, 95% CI 0.78-1.93). PCI was associated with a markedly lower rate of stroke at 30-day follow-up in octogenarians (OR 0.14, 95% CI 0.02-0.76) but an overall higher rate of repeat revascularization. At ≥36-months, MACCE (OR 1.26,95% CI 0.99-1.60) and all-cause mortality (OR 1.39, 95% CI 1.00-1.93) showed a trend favoring CABG but did not reach statistical significance. On meta-regression, PCI was associated with a higher mortality with advancing age (coefficient=0.1033, p=0.042).Conclusions: PCI was associated with a markedly lower rate of early stroke in octogenarians as compared to CABG. All-cause mortality was comparable between the two arms with a trend favoring CABG at ≥36-months.PCI was however associated with increasing mortality with advancing age as compared to CABG

Teaching lean construction: perspectives on theory and practice

This paper builds on the IGLC paper, “Different Perspectives on Teaching Lean Construction,” presented last year by Tsao et al. that documented teaching approaches from three different Lean Construction (LC) university course offerings. It aggregated the approaches taken by the course offerings, the Lean Construction Institute (LCI), and the Associated General Contractors of America to develop recommendations for learning modules, outcomes, and strategies for an introductory LC university course. This paper provides four additional distinct perspectives to continue the conversation about teaching LC in a university setting. It illustrates the authors’ differences in teaching approaches, experiences, and lessons learned from course offerings in the United States and Lebanon. The paper offers additional ideas for providing “proof of concept” to students and further illustrates how teaching LC effectively requires a combination of readings, lectures, discussions, simulation exercises, field trips, and guest speakers to mix theory with action. The paper then aggregates seven teaching perspectives in a single table to provide an overview of different approaches for teaching an introductory university-level course on LC

Evaluating the taste-masking ability and sensory attributes of alginate-encapsulated black seed oil

Introduction:  This study aimed to evaluate the sensory attributes of alginate-encapsulated black seed oil in 12 healthy volunteers. Black seed oil, derived from Nigella sativa seeds, is known for its therapeutic properties but is characterized by a pungent taste. Alginate, a hydrophilic polysaccharide polymer derived from brown seaweeds, forms water-insoluble gels in the presence of divalent metal ions such as calcium ions. Alginate finds applications in various fields, including food, pharmaceuticals, and biotechnology engineering. Method:  The ionic gelation method was employed to encapsulate black seed oil within alginate beads for taste-masking and to enhance its sensory characteristics. Sensory analysis was conducted to assess the smell, taste, taste masking, aftertaste, and texture acceptability of different formulations, including blank beads (negative control), black seed oil (positive control), black seed oil-alginate beads with and without added flavours (vanilla, chocolate, orange, and sugar), in both dried and wet forms, and a commercial black seed oil soft-gelatine capsule. Results: The results showed that encapsulating black seed oil within alginate beads significantly improved its taste and aftertaste, and the addition of flavours further enhanced the smell. Vanilla and orange flavours were found to be the most effective in improving palatability and taste masking ability of the beads in both wet and dried forms, surpassing sugar and chocolate flavours. However, sugar is preferred in the dried form alone. Conclusion:  Overall, the study demonstrated the potential of alginate encapsulation to mask the taste of black seed oil and improve its sensory attributes, offering broad applications for enhancing the palatability of other unpleasant bio-compounds