156 research outputs found
Neutral Higgs sector of the next-to-minimal supersymmetric standard model with explicit CP violation
The neutral Higgs sector of the next-to-minimal supersymmetric standard model
(NMSSM) with explicit CP violation is investigated at the 1-loop level, using
the effective potential method; not only the loops involving the third
generation of quarks and scalar quarks, but also the loops involving boson,
charged Higgs boson, and chargino are taken into account. It is found that for
some parameter values of the NMSSM the contributions from the boson,
charged Higgs boson, and chargino loops may modify the masses of the neutral
Higgs bosons and the mixings among them significantly, depending on the CP
phase. In collisions, the prospects for discovering neutral Higgs
bosons are investigated within the context of the NMSSM with explicit CP
violation when the dominant component of the lightest neutral Higgs boson is
the Higgs singlet field of the NMSSM.Comment: Latex, 23 pages, 6 figure
Neutral Higgs bosons in the MNMSSM with explicit CP violation
Within the framework of the minimal non-minimal supersymmetric standard model
(MNMSSM) with tadpole terms, CP violation effects in the Higgs sector are
investigated at the one-loop level, where the radiative corrections from the
loops of the quark and squarks of the third generation are taken into account.
Assuming that the squark masses are not degenerate, the radiative corrections
due to the stop and sbottom quarks give rise to CP phases, which trigger the CP
violation explicitly in the Higgs sector of the MNMSSM. The masses, the
branching ratios for dominant decay channels, and the total decay widths of the
five neutral Higgs bosons in the MNMSSM are calculated in the presence of the
explicit CP violation. The dependence of these quantities on the CP phases is
quite recognizable, for given parameter values.Comment: 25 pages, 8 figure
Charged Higgs boson in the next-to-minimal supersymmetric standard model with explicit CP violation
The phenomenology of the explicit CP violation in the Higgs sector of the
next-to-minimal supersymmetric standard model (NMSSM) is investigated, with
emphasis on the charged Higgs boson. The radiative corrections due to both
quarks and scalar-quarks of the third generation are taken into account, and
the negative result of the search for the Higgs bosons at CERN LEP2, with the
discovery limit of 0.1 pb, is imposed as a constraint. It is found that there
are parameter regions of the NMSSM where the lightest neutral Higgs boson may
even be massless, without being detected at LEP2. This implies that the LEP2
data do not contradict the existence of a massless neutral Higgs boson in the
NMSSM. For the charged Higgs boson, the radiative corrections to its mass may
be negative in some parameter regions of the NMSSM. The phenomenological lower
bound on the radiatively corrected mass of the charged Higgs boson is increased
as the CP violation becomes maximal, i.e., as the CP violating phase becomes
. At the maximal CP violation, its lower bound is about 110 GeV for 5
40. The vacuum expectation value (VEV) of the
neutral Higgs singlet is shown to be no smaller than 16 GeV for any parameter
values of the NMSSM with explicit CP violation. This value of the lower limit
is found to increase up to about 45 GeV as the ratio () of the VEVs
of the two Higgs doublets decreases to smaller values ( 2). The discovery
limit of the Higgs boson search at LEP2 is found to cover about a half of the
kinematically allowed part of the whole parameter space of the NMSSM, and the
portion is roughly stable against the CP violating phase.Comment: Latex, 24 pages, 6 figure
Possibility of spontaneous CP violation in the nonminimal supersymmetric standard model with two neutral Higgs singlets
A supersymmetric standard model with two Higgs doublets and two Higgs
singlets is investigated if it can accommodate the possibility of spontaneous
CP violation. Assuming the degeneracy of the scalar quark masses of the third
generation, we find that spontaneous CP violation in the Higgs sector is viable
in our model. In the case of spontaneous CP violation, the masses of the
lightest two neutral Higgs bosons are estimated to be 80 and 125 GeV for some
parameter values in our model, which, are consistent with LEP2 data.Comment: 18 pages, 3figure
Spontaneous Violation of the CP Symmetry in the Higgs Sector of the Next-to-Minimal Supersymmetric Model
The spontaneous violation of the CP symmetry in the next-to-minimal
supersymmetric standard Model (NMSSM) is investigated. It is found that the
spontaneous violation of the CP symmetry can occur in the Higgs sector of the
NMSSM for a wide region of the parameter space of the model, at the 1-loop
level where the radiative corrections due to the top quark and scalar-top quark
loops are found to generate the scalar-pseudoscalar mixings between the two
Higgs doublets of the NMSSM. In our model, we assume that the masses of the
left-handed and the right-handed scalar-top quarks are not degenerate. And we
investigate our model anaytically: We derive analytical formulae of the 1-loop
mass matrix for the neutral Higgs bosons. We calculate the upper bound on the
lightest neutral Higgs boson mass under the assumption. It is found to be about
140 GeV for our choice of parameter values in the presence of the spontaneous
violation of the CP symmetry in the NMSSM. Thus, the possibility of the
spontaneous violation of the CP symmetry is not completely ruled out in the
Higgs sector of the NMSSM if the masses of the left-handed and the right-handed
scalar-top quarks are not degenerate. Further, the phenomenology of the
- mixing within the context of our model is studied. The lower
bound on CP violating phase in the - mixing is found to increase
if either decreases or increases.Comment: 21 pages, 5 figures, To appear in Phys. Rev.
Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo
Microglia are brain-resident macrophages with trophic and phagocytic functions. Dominant loss-of-function mutations in a key microglia regulator, colony-stimulating factor 1 receptor (CSF1R), cause adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a progressive white matter disorder. Because it remains unclear precisely how CSF1R mutations affect microglia, we generated an allelic series of csf1r mutants in zebrafish to identify csf1r-dependent microglia changes. We found that csf1r mutations led to aberrant microglia density and distribution and regional loss of microglia. The remaining microglia still had a microglia-specific gene expression signature, indicating that they had differentiated normally. Strikingly, we also observed lower microglia numbers and widespread microglia depletion in postmortem brain tissue of ALSP patients. Both in zebrafish and in human disease, local microglia loss also presented in regions without obvious pathology. Together, this implies that CSF1R mainly regulates microglia density and that early loss of microglia may contribute to ALSP pathogenesis. Oosterhof et al. show that colony-stimulating factor 1 receptor (CSF1R) primarily regulates microglia density and not their normal differentiation. In addition, they find widespread depletion of microglia in CSF1R-haploinsufficient zebrafish and leukodystrophy patients, also in the absence of pathology, indicating that microglia depletion may contribute to loss of white matter
Combining series elastic actuation and magneto-rheological damping for the control of agile locomotion
All-terrain robot locomotion is an active topic of research. Search and rescue maneuvers and exploratory missions could benefit from robots with the abilities of real animals. However, technological barriers exist to ultimately achieving the actuation system, which is able to meet the exigent requirements of these robots. This paper describes the locomotioncontrol of a leg prototype, designed and developed to make a quadruped walk dynamically while exhibiting compliant interaction with the environment. The actuation system of the leg is based on the hybrid use of series elasticity and magneto-rheological dampers, which provide variable compliance for natural-looking motion and improved interaction with the ground. The locomotioncontrol architecture has been proposed to exploit natural leg dynamics in order to improve energy efficiency. Results show that the controller achieves a significant reduction in energy consumption during the leg swing phase thanks to the exploitation of inherent leg dynamics. Added to this, experiments with the real leg prototype show that the combined use of series elasticity and magneto-rheologicaldamping at the knee provide a 20 % reduction in the energy wasted in braking the knee during its extension in the leg stance phase
Exploring quantitative group-wise differentiation of Alzheimer's disease and behavioural variant frontotemporal dementia using tract-specific microstructural white matter and functional connectivity measures at multiple time points
Objectives This study explored group-wise quantitative measures of tract-specific white matter (WM) microstructure and functional default mode network (DMN) connectivity to establish an initial indication of their clinical applicability for early-stage and
follow-up differential diagnosis of Alzheimerâs disease (AD) and behavioural variant frontotemporal dementia (bvFTD).
Methods Eleven AD and 12 bvFTD early-stage patients and 18 controls underwent diffusion tensor imaging and resting state
functional magnetic resonance imaging at 3 T. All AD and 6 bvFTD patients underwent the same protocol at 1-year follow-up.
Functional connectivity measures of DMN and WM tract-specific diffusivity measures were determined for all groups.
Exploratory analyses were performed to compare all measures between the three groups at baseline and between patients at
follow-up. Additionally, the difference between baseline and follow-up diffusivity measures in AD and bvFTD patients was
compared.
Results Functional connectivity of the DMN was not different between groups at baseline and at follow-up. Diffusion abnormalities were observed widely in bvFTD and regionally in the hippocampal cingulum in AD. The extent of the differences
between bvFTD and AD was diminished at follow-up, yet abnormalities were still more pronounced in bvFTD. The rate of
change was similar in bvFTD and AD.
Conclusions This study provides a tentative indication that quantitative tract-specific microstructural WM abnormalities, but not
quantitative functional connectivity of the DMN, may aid early-stage and follow-up differential diagnosis of bvFTD and AD.
Specifically, pronounced microstructural changes in anterior WM tracts may characterise bvFTD, whereas microstructural
abnormalities of the hippocampal cingulum may characterise AD
Higgs Scalars in the Minimal Non-minimal Supersymmetric Standard Model
We consider the simplest and most economic version among the proposed
non-minimal supersymmetric models, in which the -parameter is promoted to
a singlet superfield, whose all self-couplings are absent from the
renormalizable superpotential. Such a particularly simple form of the
renormalizable superpotential may be enforced by discrete -symmetries which
are extended to the gravity-induced non-renormalizable operators as well. We
show explicitly that within the supergravity-mediated supersymmetry-breaking
scenario, the potentially dangerous divergent tadpoles associated with the
presence of the gauge singlet first appear at loop levels higher than 5 and
therefore do not destabilize the gauge hierarchy. The model provides a natural
explanation for the origin of the -term, without suffering from the
visible axion or the cosmological domain-wall problem. Focusing on the Higgs
sector of this minimal non-minimal supersymmetric standard model, we calculate
its effective Higgs potential by integrating out the dominant quantum effects
due to stop squarks. We then discuss the phenomenological implications of the
Higgs scalars predicted by the theory for the present and future high-energy
colliders. In particular, we find that our new minimal non-minimal
supersymmetric model can naturally accommodate a relatively light charged Higgs
boson, with a mass close to the present experimental lower bound.Comment: 63 pages (12 figures), extended versio
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