102 research outputs found

    A Social Choice Approach to Graded Soft Sets: slides for FUZZ-IEEE 2017

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    [EN]We establish a correspondence between ideas from soft computing and social choice. This connection permits to draw bridges between choice mechanisms in both frameworks. We prove that both Soft sets and the novel concept of Graded soft sets can be faithfully represented by well-established voting situations in Social Choice. To be precise, their decision making mechanism by choice values coincides with approval voting and the Borda rule respectively. This analysis lays the basis for new insights into soft-set-inspired decision making with a social choice foundatio

    Controversy and consensus on the management of elevated sperm DNA fragmentation in male infertility: a global survey, current guidelines, and expert recommendations

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    PURPOSE: Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition. MATERIALS AND METHODS: An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method. RESULTS: A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4-6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated. CONCLUSIONS: This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians

    The Debate About the Consequences of Job Displacement

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    Technical aspects and clinical limitations of sperm DNA fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations.

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    PURPOSE: Sperm DNA fragmentation (SDF) is a functional sperm abnormality that can impact reproductive potential, for which four assays have been described in the recently published sixth edition of the WHO laboratory manual for the examination and processing of human semen. The purpose of this study was to examine the global practices related to the use of SDF assays and investigate the barriers and limitations that clinicians face in incorporating these tests into their practice. MATERIALS AND METHODS: Clinicians managing male infertility were invited to complete an online survey on practices related to SDF diagnostic and treatment approaches. Their responses related to the technical aspects of SDF testing, current professional society guidelines, and the literature were used to generate expert recommendations via the Delphi method. Finally, challenges related to SDF that the clinicians encounter in their daily practice were captured. RESULTS: The survey was completed by 436 reproductive clinicians. Overall, terminal deoxynucleotidyl transferase deoxyuridine triphosphate Nick-End Labeling (TUNEL) is the most commonly used assay chosen by 28.6%, followed by the sperm chromatin structure assay (24.1%), and the sperm chromatin dispersion (19.1%). The choice of the assay was largely influenced by availability (70% of respondents). A threshold of 30% was the most selected cut-off value for elevated SDF by 33.7% of clinicians. Of respondents, 53.6% recommend SDF testing after 3 to 5 days of abstinence. Although 75.3% believe SDF testing can provide an explanation for many unknown causes of infertility, the main limiting factors selected by respondents are a lack of professional society guideline recommendations (62.7%) and an absence of globally accepted references for SDF interpretation (50.3%). CONCLUSIONS: This study represents the largest global survey on the technical aspects of SDF testing as well as the barriers encountered by clinicians. Unified global recommendations regarding clinician implementation and standard laboratory interpretation of SDF testing are crucial

    Do values matter? The impact of work ethic and traditional gender role values on female labour market supply

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    Contains fulltext : 126517.pdf (publisher's version ) (Closed access)This article aims to gain a better understanding of the explanatory value of work ethic and traditional gender role values with regard to variation in female labour market supply. Although women's labour market participation has increased dramatically over the past decades, it still lacks behind that of men. A high female participation rate is desirable for several reasons, for instance to cover rising costs due to the ageing of society. The existing literature has mostly focused on micro-economic and macro factors to explain differences between women in participation rate. However, more recently it has been argued that women's values may also play an important role in women's labour market decisions. Work ethic, expressing the moral duty to work in terms of paid employment, is argued to positively affect women's labour supply. However, it is argued that it can have negative implications too if women who hold more traditional gender role values interpret work and work ethic in terms of housework or in terms of paid employment for men only. This exemplifies the need to study both values at the same time. We used longitudinal Dutch data (LISS panel, 2007-2010) and estimated both cross-sectional and longitudinal models. Both types of models revealed a similar pattern: work ethic is positively associated with women's labour market participation, but only if we take into account women's gender role values, which negatively relate to women's labour market supply.18 p
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