We have emotions but can’t show them! Authoritarian leadership, emotion suppression climate, and team performance

How do authoritarian leaders in modern organizations influence work team emotional climate and performance? Defining authoritarian leadership as an ambient, demanding, and controlling leadership style, we conducted a survey study of 252 leaders and 765 subordinates matched in 227 work teams in three large public Japanese organizations. The results indicate that authoritarian leaders are more likely to create a team climate of emotion suppression, which induces a higher level of team emotional exhaustion that negatively impacts team performance. Furthermore, we found that authoritarian leaders’ own emotion suppression enhances the above sequential mediation effects, i.e. the more emotion suppression the authoritarian leader him/herself exercises, the stronger the team climate of emotion suppression, the higher the level of team emotional exhaustion, and the lower the team performance. These findings suggest that leadership effectiveness may be improved if leaders can reduce their authoritarian behaviors and identify appropriate channels for employees to release emotions in the workplace

Transformation and reconstruction towards two-dimensional atomic laminates

Two-dimensional (2D) nanomaterials derived from non-van der Waals solids are promising due to their fantastic physical and chemical properties, but it remains challenging to obtain 2D atomic laminates with high stability owing to the strong intrinsic covalent/metallic bonds and highly exposed active surface. Here, we report a versatile and scalable protocol to produce 2D atomic laminates, based on an unexpected topological transformation of MAX phases under hydrogen chloride gas, and/or subsequent reconstruction under some programmed gases/vapors. In contrast to the known approaches with liquid or molten medium, our method involves in a gas-phase reaction with fast thermodynamics for A layers and positive Gibbs free energies for MX slabs. Remarkably, through subsequent reconstruction in some active gases/vapors (O2, H2S, P, CH4, Al and Sn metal vapors), a big family of 2D atomic laminates with elusive configurations as well as high chemical/thermal stabilities and tunable electrical properties (from metallic to semiconductor-like behaviors) are achieved. Moreover, the resultant 2D atomic laminates can be facilely scaled up to 10 kilograms. We believe that the 2D atomic laminates would have broad applications in catalysis, energy storage, electromagnetic shielding interface and microwave absorption

Comprehensive analysis of the cuproptosis-related gene DLD across cancers: A potential prognostic and immunotherapeutic target

DLD is a key gene involved in “cuproptosis,” but its roles in tumor progression and immunity remain unclear. Exploring the potential mechanisms and biological roles of DLD may provide new insights for therapeutic strategies for tumors. In the present study, we analyzed the role of DLD in a variety of tumors by using several bioinformatic tools. The results showed that compared with normal tissues, tumor tissues representing multiple cancers showed significant differential expression of DLD. High DLD expression was associated with a good prognosis in BRCA, KICH, and LUAD. Conversely, high expression levels of DLD were detrimental to patient prognosis in many other tumors, such as COAD, KIRC, and KIRP. In addition, the associations of DLD with infiltrating immune cells, genetic alterations and methylation levels across cancers were assessed. Aberrant expression of DLD was positively correlated with most infiltrating immune cells, especially neutrophils. The DLD methylation level was significantly decreased in COAD, LIHC, and LUSC but significantly increased in BRCA. DLD had the highest mutation rate (6.04%) in ESCA. In LUSC, patients with genetic alterations in DLD showed a poorer prognosis. At the single-cell level, the roles of DLD in regulating cancer-associated biological functions, such as metastasis, inflammation, and differentiation, were explored. Afterward, we further investigated whether several disease-associated genes could be correlated with DLD. GO enrichment analysis indicated that DLD-related genes were mainly associated with mitochondria-related cellular components, aerobic respiration and the tricarboxylic acid cycle. Finally, the correlations between DLD expression and immunomodulatory genes, immune checkpoints, and sensitivity to some antitumor drugs were investigated. It is worth noting that DLD expression was positively correlated with immune checkpoint genes and immunomodulatory genes in most cancers. In conclusion, this study comprehensively analyzed the differential expression, prognostic value and immune cell infiltration-related function of DLD across cancers. Our results suggest that DLD has great potential to serve as a candidate marker for pancancer prognosis and immunotherapy and may provide a new direction for cancer treatment development

TFCP2 Genetic Polymorphism Is Associated with Predisposition to and Transplant Prognosis of Hepatocellular Carcinoma

TFCP2 is an oncogene and plays crucial roles in the incidence and progression of hepatocellular carcinoma (HCC). However, no reports are available on the impact of TFCP2 genetic polymorphism on the susceptibility to and the transplant prognosis of HCC. Here, we genotyped 7 SNPs of TFCP2 in a case-control study of 119 patients with HCC and 200 patients with chronic liver disease. Of the 7 SNPs in TFCP2, rs7959378 distributed differentially between patients with versus patients without HCC. The patients with the CA (OR = 0.58, 95% CI = 0.35–0.96), the CC (OR = 0.39, 95% CI = 0.20–0.76), and the CA/CC (OR = 0.52, 95% CI = 0.32–0.83) genotypes had significantly decreased risk for HCC compared with those carrying the rs7959378 AA genotype. After adjusting for confounding factors, rs7959378 still conferred significant risk for HCC. Furthermore, the patients who carried rs7959378 AC/CC had a higher overall survival and lower relapse-free survival than those with the rs7959378 AA genotype. Similar results were found in the multivariate analysis adjusted by AFP, tumor size and tumor number, and differentiation. These findings indicate that rs7959378 is associated with the risk of HCC in patient with chronic liver disease and prognosis of HCC patients after liver transplantation

The Chinese Open Science Network (COSN): Building an Open Science Community From Scratch

Open Science is becoming a mainstream scientific ideology in psychology and related fields. However, researchers, especially early-career researchers (ECRs) in developing countries, are facing significant hurdles in engaging in Open Science and moving it forward. In China, various societal and cultural factors discourage ECRs from participating in Open Science, such as the lack of dedicated communication channels and the norm of modesty. To make the voice of Open Science heard by Chinese-speaking ECRs and scholars at large, the Chinese Open Science Network (COSN) was initiated in 2016. With its core values being grassroots-oriented, diversity, and inclusivity, COSN has grown from a small Open Science interest group to a recognized network both in the Chinese-speaking research community and the international Open Science community. So far, COSN has organized three in-person workshops, 12 tutorials, 48 talks, and 55 journal club sessions and translated 15 Open Science-related articles and blogs from English to Chinese. Currently, the main social media account of COSN (i.e., the WeChat Official Account) has more than 23,000 subscribers, and more than 1,000 researchers/students actively participate in the discussions on Open Science. In this article, we share our experience in building such a network to encourage ECRs in developing countries to start their own Open Science initiatives and engage in the global Open Science movement. We foresee great collaborative efforts of COSN together with all other local and international networks to further accelerate the Open Science movement

Pengaruh Pendekatan Pembelajaran Matematika Realistik Terhadap Prestasi Belajar Matematika Ditinjau Dari Kemampuan Numerik Siswa Kelas VIII SMP Negeri 2 Amlapura

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan pengaruh pendekatan pembelajaran matematika realistik terhadap prestasi belajar matematika ditinjau dari kemampuan numerik siswa. Penelitian ini merupakan eksperimen semu dilaksanakan dengan menggunakan rancangan the post test only control group design. Populasinya adalah seluruh siswa kelas VIII SMP Negeri 2 Amlapura tahun pelajaran 2013-2014. Dari delapan kelas yang ada, empat kelas dipilih sebagai sampel yakni dua kelas sebagai kelas eksperimen dan dua kelas sebagai kelas kontrol yang diambil dengan teknik random. Data penelitian dikumpulkan menggunakan tes, yaitu tes kemampuan numerik dan tes prestasi belajar matematika. Data yang diperoleh dianalisis dengan analisis varians dua jalur dilanjutkan dengan uji Tukey. Berdasarkan hasil analisis data dan pembahasan, dapat disimpulkan, terdapat perbedaan yang signifikan prestasi belajar matematika antara siswa yang mengikuti pendekatan pembelajaran matematika realistik dengan siswa yang mengikuti pendekatan pembelajaran konvensional. Terdapat pengaruh interaksi antara pendekatan pembelajaran matematika realistik dan kemampuan numerik terhadap prestasi belajar matematika. Pada Siswa yang memiliki kemampuan numerik tinggi, prestasi belajar matematika siswa yang mengikuti pendekatan pembelajaran matematika realistik lebih baik daripada pendekatan konvensional. Pada siswa yang memiliki kemampuan numerik rendah, prestasi belajar matematika siswa yang mengikuti pendekatan pembelajaran matematika realistik tetap lebih tinggi dari siswa yang mengikuti pendekatan pembelajaran konvensional.Kata Kunci : pendekatan pembelajaran matematika realistik, kemampuan numerik, dan prestasi belajar matematika The study aimed at finding out and describing the contribution of realistic mathematic instructional approach towards mathematic learning achievement viewed from numeric skills. It was a quasi-experimental research by utilizing the post test only control group design. The study involved all students class VIII SMP Negeri 2 Amlapura in 2013-2014 as the population. Four classes of the students were chosen from eight parallel classes as the samples consisting of two classes as experimental and another two classes as control groups. They were determined based on random technique. The data were collected by testing, involving numeric ability and mathematic achievement tests. They were analysed based on two tailed variant analysis followed by Tukey-test. The results indicated that there was a significant difference between mathematic learning achievement of the students joining realistic mathematic instruction and those joining a conventional approach. There was an interactional contribution of realistic mathematic instructional approach and numeric ability towards mathematic learning achievement. The students having higher numeric skills, when joining realistic mathematic instruction approach their mathematic learning achievement was found better or higher than those joining a conventional approach. The students having lower numeric skills, when joining realistic mathematic instruction approach, their mathematic learning achievement was found better or higher than those joining a conventional approach

Observation of electronic nematicity driven by three-dimensional charge density wave in kagome lattice KV3_3Sb5_5

Kagome superconductors AV$_3$Sb$_5$ (A = K, Rb, Cs) provide a fertile playground for studying various intriguing phenomena such as non-trivial band topology, superconductivity, giant anomalous Hall effect, and charge density wave (CDW). Remarkably, the recent discovery of $C_2$ symmetric nematic phase prior to the superconducting state in AV$_3$Sb$_5$ has drawn enormous attention, as the unusual superconductivity might inherit the symmetry of the nematic phase. Although many efforts have been devoted to resolve the charge orders using real-space microscopy and transport measurements, the direct evidence on the rotation symmetry breaking of the electronic structure in the CDW state from the reciprocal space is still rare. The underlying mechanism is still ambiguous. Here, utilizing the micron-scale spatially resolved angle-resolved photoemission spectroscopy, we observed the fingerprint of band folding in the CDW phase of KV$_3$Sb$_5$, which yet demonstrates the unconventional unidirectionality, and is indicative of the rotation symmetry breaking from $C_6$ to $C_2$. We then pinpointed that the interlayer coupling between adjacent planes with $\pi$-phase offset in the 2$\times$2$\times$2 CDW phase would lead to the preferred twofold symmetric electronic structure. Time-reversal symmetry is further broken at temperatures below $\sim$ 40 K as characterized by giant anomalous Hall effect triggered by weak magnetic fields. These rarely observed unidirectional back-folded bands with time-reversal symmetry breaking in KV$_3$Sb$_5$ may provide important insights into its peculiar charge order and superconductivity

LEPREL1 Expression in Human Hepatocellular Carcinoma and Its Suppressor Role on Cell Proliferation

Background. Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies worldwide. It is characterized by its high invasive and metastatic potential. Leprecan-like 1 (LEPREL1) has been demonstrated to be downregulated in the HCC tissues in previous proteomics studies. The present study is aimed at a new understanding of LEPREL1 function in HCC. Methods. Quantitative RT-PCR, immunohistochemical analysis, and western blot analysis were used to evaluate the expression of LEPREL1 between the paired HCC tumor and nontumorous tissues. The biology function of LEPREL1 was investigated by Cell Counting Kit-8 (CCK8) assay and colony formation assay in HepG2 and Bel-7402 cells. Results. The levels of LEPREL1 mRNA and protein were significantly lower in the HCC tissues as compared to those of the nontumorous tissues. Reduced LEPREL1 expression was not associated with conventional clinical parameters of HCC. Overexpression of LEPREL1 in HepG2 and Bel-7402 cells inhibited cell proliferation (P<0.01) and colony formation (P<0.05). LEPREL1 suppressed tumor cell proliferation through regulation of the cell cycle by downregulation of cyclins. Conclusions. Clinical parameters analysis suggested that LEPREL1 was an independent factor in the development of HCC. The biology function experiments showed that LEPREL1 might serve as a potential tumor suppressor gene by inhibiting the HCC cell proliferation