A horizontal alignment tool for numerical trend discovery in sequence data: application to protein hydropathy.

PMC3794901An algorithm is presented that returns the optimal pairwise gapped alignment of two sets of signed numerical sequence values. One distinguishing feature of this algorithm is a flexible comparison engine (based on both relative shape and absolute similarity measures) that does not rely on explicit gap penalties. Additionally, an empirical probability model is developed to estimate the significance of the returned alignment with respect to randomized data. The algorithm's utility for biological hypothesis formulation is demonstrated with test cases including database search and pairwise alignment of protein hydropathy. However, the algorithm and probability model could possibly be extended to accommodate other diverse types of protein or nucleic acid data, including positional thermodynamic stability and mRNA translation efficiency. The algorithm requires only numerical values as input and will readily compare data other than protein hydropathy. The tool is therefore expected to complement, rather than replace, existing sequence and structure based tools and may inform medical discovery, as exemplified by proposed similarity between a chlamydial ORFan protein and bacterial colicin pore-forming domain. The source code, documentation, and a basic web-server application are available.JH Libraries Open Access Fun

Effects of emotional labor on job satisfaction : the role of the degree of customer contact and coping strategies

submitted by Amela HadzipasicUniversität Innsbruck, Masterarbeit, 2018(VLID)256646

Effects of emotional labor on job satisfaction : the role of the degree of customer contact and coping strategies

How do I feel, what I am supposed to feel, without feeling dishonest? Past research on organizational behavior used to ignore emotions (Arvey, Renz, & Watson, 1998; Putnam & Mumby, 1993). This view is changing at the moment, and researchers examine how emotions at the workplace can help to explain outcomes for the individuals and for the organization (Grandey, 2000). With reference to emotional labor theory, this master thesis will investigate the relationship between emotional labor and other factors like, job satisfaction or well-being. The data that is needed to explain these relationships and effects, is gathered by conducting a self-administered web survey. The results indicated, that emotional labor has a negative effect on job satisfaction, and job satisfaction drives the well-being of employees. This study integrated three moderators into their research model, namely support, degree of customer contact, and coping strategies. No significant moderating effect was found for none of the three moderator variables. The findings indicate, that the only coping strategy that is able to decrease the negative effects of emotional labor, is the emotion management strategy that is called naturally felt emotions. Findings of this research will help to understand the effects of emotional labor on other employee related factors, such as job satisfaction or well-being. Furthermore, reasons are provided why it is important that companies pay attention to the emotion management of their employees. Theoretical and managerial implications are discussed.submitted by Amela HadzipasicMasterarbeit Universität Innsbruck 201

QUALITY OF LIFE OF ELDERLY PEOPLE WITH VISUAL IMPAIRMENT IN RELATION TO THE DEGREE OF VISUAL IMPAIRMENT

The main goal of this study was to examine the differences in the quality of life of the elderly with impaired vision in relation to the degree of visual impairment. The research included a total of 40 elder respondents, visually impaired, both genders, located and accommodated in the Public Institution “Retirement Home” in Tuzla and the retirement home “Vita Nostra” in Bihać. The analysis of the obtained results indicates that the degree of visual impairment has an impact on the quality of life of the elderly with impaired vision, people with severe visual impairment have the poorest quality of life.</jats:p