4,125 research outputs found

    A theoretical treatment of the Schwarz-Hora effect

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    Contextualizing the Global Nursing Care Chain: International Migration and the Status of Nursing in Kerala, India

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    In this article I explore the issue of nursing status in Kerala, India and how over time a colonial discourse of casteā€based pollution has given way to a discourse of sexual pollution under expanding migratory opportunities. Based on survey and qualitative research findings, I caution that the improving occupational status of nursing in India is not directly mapped onto social status, and this is particularly evident in the matrimonial market. In the light of these findings I argue that global nursing care chain (GNCC) analysis must assess more than just workplace contexts in order to conceptualize how global care chains (GCCs) interlock, and how they are differentiated from each other

    Sources of Water for Communities in Northeastern Illinois

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    published or submitted for publicationis peer reviewedOpe

    Changing Groundwater Levels in the Sandstone Aquifers of Northern Illinois and Southern Wisconsin: Impacts on Available Water Supply

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    In 2014-15, the Illinois State Water Survey conducted their largest synoptic measurement of water levels (i.e., heads) in Cambrian-Ordovician sandstone wells since 1980. The study covered 33 counties in the northern half of Illinois where demands for water are satisfied, in part, by sandstone aquifers. The Wisconsin Geological and Natural History Survey also measured sandstone wells in 10 counties in southern Wisconsin. These observations were used to generate head contours of the sandstone aquifers. These contours provide insight into the direction and magnitude of groundwater flow. They also can be compared with historic measurements, providing insight into the impact of changing groundwater withdrawals through time. In predevelopment conditions, heads in the Cambrian-Ordovician sandstone aquifers were near or above land surface. Due to pumping from the sandstone aquifers, heads have decreased over time; this decrease is referred to as drawdown. In 2014, drawdown in northeastern Illinois was typically over 300 ft and exceeded 800 ft in the Joliet region. Three factors drove this large drawdown. First, demands for water from sandstone aquifers are much greater in northeastern Illinois than in the rest of the study region. Second, the sandstone aquifers are overlain by aquitards, which are low permeable materials that limit vertical infiltration of water. Third, the Sandwich Fault Zone limits water flowing into the sandstone aquifers of northeastern Illinois from the south. Heads near the center of the cone of depression continue to have a decreasing trend. The more severe drawdown in northeastern Illinois has resulted in local areas where heads have fallen below the top of the sandstone, known as desaturation. Desaturation of a sandstone aquifer can create a number of water quality and quantity concerns. The uppermost sandstone, the St. Peter, was observed to be partially desaturated in portions of Will, Kane, and Kendall Counties under non-pumping conditions. Other areas in these counties are at risk of desaturation under pumping conditions or with the installation of additional wells connecting the St. Peter to deeper, more heavily stressed sandstones. Simulations from a groundwater flow model indicate that the risk of desaturation will increase with increased future withdrawals. Despite the relatively small demand for water throughout much of central Illinois, heads have been declining since predevelopment, likely due to the shale overlying the sandstone. This shale serves as an aquitard, minimizing vertical infiltration of groundwater to the sandstone. Sustained drawdown in this region could potentially induce flow from the southern half of the state, where water in the sandstone is highly saline and not suitable as a drinking water supply. Drawdown in northwestern Illinois was also typically small (<100 ft), primarily due to two factors: 1) low demands from the sandstone aquifers and 2) the absence of shale aquitards. The notable exception is in Winnebago County, near Rockford, where demands are historically high and drawdown was on the order of 100-200 ft. While the quantity of water in the aquifer is not a concern in this region, large withdrawals could result in reductions of natural groundwater discharge to surface waters, impacting stream ecosystems under low flow conditions. Drawdown since predevelopment was over 300 ft in southeastern Wisconsin, with the greatest drawdown in Waukesha County of over 400 ft. Recent trends indicate heads in the Waukesha area are recovering, although they are still well below predevelopment levels. [This report is also associated with the fact sheets: Changing Groundwater Levels in the Cambrian-Ordovician Sandstone Aquifers of Northern Illinois, 1980-2014, Groundwater Availability in Northeastern Illinois from Deep Sandstone Aquifers, and Sources of Water for Communities in Northeastern Illinois.published or submitted for publicationis peer reviewedOpe

    Water Supply Planning: Middle Illinois Progress Report

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    This report presents a summary of 1) the technical information assembled to describe existing water availability and sources of supply within the 7-county (LaSalle, Livingston, Marshall, Peoria, Putnam, Stark, and Woodford Counties) Middle Illinois River Region in central Illinois (Figures 1 and 2) and 2) the development of preliminary computer models that will be used in future studies to estimate impacts to water availability resulting from future water development in the region. Through funding by the Illinois Department of Natural Resources (IDNR), the Illinois State Water Survey (ISWS) and Illinois State Geological Survey (ISGS) prepared this document for the Middle Illinois Regional Water Supply Planning Committee (MIRWSPC) to aid in the development of a plan for meeting the future growth of water supply demands within the basin to the year 2060. It contains background information to provide an overview of management criteria and an understanding of the constraints and policies used in conducting analyses and making decisions concerning water usage. Models will be applied to a broad range of conditions, including a set of selected future water use scenarios to more fully characterize water availability within the Middle Illinois River Region to the year 2060. In addition, as the MIRWSPC deliberates and prepares its water supply planning document, the information presented in this report will be reviewed and, in some cases, additional analysis may be performed and results revised. A more complete reporting of the model development, the results of the scenario simulations, and subsequent work concerning water availability will be published at the end of that forthcoming study. The existing technical information compiled as the first task of this study includes a review of previous analyses and publications dealing with the Middle Illinois River Regionā€™s water resources; collection of hydrogeological and hydrologic data, primarily as needed for modeling; and, in certain cases, additional analyses of that data, such as data mining of well records and yield analyses of surface water supply sources. This compiled information focuses on the three primary sources of water supply within the Middle Illinois River watershed: 1) direct withdrawals from the Illinois River; 2) public supply systems using the Vermilion River and off-channel reservoirs at Pontiac and Streator; and 3) groundwater from within the Middle Illinois River basin. A companion report has been published (Meyer et al., In preparation) evaluating water demand scenarios out to 2060 for the Middle Illinois River, Northwest Illinois, and Kankakee River Regions.published or submitted for publicationis peer reviewedOpe

    Polymerization-based signal amplification for paper-based immunoassays

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    Diagnostic tests in resource-limited settings require technologies that are affordable and easy to use with minimal infrastructure. Colorimetric detection methods that produce results that are readable by eye, without reliance on specialized and expensive equipment, have great utility in these settings. We report a colorimetric method that integrates a paper-based immunoassay with a rapid, visible-light-induced polymerization to provide high visual contrast between a positive and a negative result. Using Plasmodium falciparum histidine-rich protein 2 as an example, we demonstrate that this method allows visual detection of proteins in complex matrices such as human serum and provides quantitative information regarding analyte levels when combined with cellphone-based imaging. It also allows the user to decouple the capture of analyte from signal amplification and visualization steps.Bill & Melinda Gates Foundation (Award 51308)United States. Defense Advanced Research Projects Agency (HR0011-12-2-0010)National Science Foundation (U.S.). Graduate Research FellowshipBurroughs Wellcome Fund (Career Award at the Scientific Interface

    Should tumor VEGF expression influence decisions on combining low-dose chemotherapy with antiangiogenic therapy? Preclinical modeling in ovarian cancer

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    Because of its low toxicity, low-dose (LD) chemotherapy is ideally suited for combination with antiangiogenic drugs. We investigated the impact of tumor vascular endothelial growth factor A (VEGF-A) expression on the efficacy of LD paclitaxel chemotherapy and its interactions with the tyrosine kinase inhibitor SU5416 in the ID8 and ID8-Vegf models of ovarian cancer. Functional linear models using weighted penalized least squares were utilized to identify interactions between Vegf, LD paclitaxel and antiangiogenic therapy. LD paclitaxel yielded additive effects with antiangiogenic therapy against tumors with low Vegf expression, while it exhibited antagonism to antiangiogenic therapy in tumors with high Vegf expression. This is the first preclinical study that models interactions of LD paclitaxel chemotherapy with antiangiogenic therapy and tumor VEGF expression and offers important lessons for the rational design of clinical trials

    Groundwater Flow Models of Illinois: Data, Processes, Model Performance, and Key Results

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    The Illinois State Water Survey (ISWS) has a long history of developing groundwater flow models to simulate water supply and groundwater contamination issues in the state of Illinois. However, past local- and regional-scale models developed by the ISWS have traditionally been project based; thus models are archived when the project is completed and may not be updated for many years. This report presents the first version of the Evolving Network of Illinois Groundwater Monitoring and Modeling Analyses (ENIGMMA), which is the framework of data, procedures, protocols, and scripts that facilitate the development of a single, continuously updated groundwater flow model and other outputs (hydrographs, maps, animations of groundwater potentiometric surfaces). This report focuses on five aspects of ENIGMMA: 1. The archived models and high-resolution datasets that serve as inputs to ENIGMMA 2. The procedures for developing model-ready datasets from these inputs 3. The Illinois Groundwater Flow Model (IGWFM), which serves as the single model that will be continuously updated by ENIGMMA 4. The ISWS Calibration Toolbox, used to facilitate a transient calibration of the IGWFM 5. Animations of groundwater potentiometric surfaces using head-specified models This report is a living document that will be updated periodically. Future updates to this report will focus on additional aspects of ENIGMMA, including the automated development of model-ready inputs and display of model outputs. Updates to this report will also chronicle any additional geologic data added to ENIGMMA, and subsequently, to the Illinois Groundwater Flow Model. Updates will also highlight both local- and regional-scale advancements made with the model, including any key results from these models. The current version of the IGWFM combines and expands on two existing groundwater flow models: 1) the Northeastern Illinois Cambrian-Ordovician Sandstone Aquifer model and 2) the East-Central Illinois Mahomet Aquifer model. In addition, the model incorporates new geologic information developed by the Illinois State Geological Survey in the Middle Illinois Water Supply Planning region. The current model domain covers large portions of Illinois, Wisconsin, Indiana, and Michigan. This large spatial extent is necessary to capture the far-reaching regional head declines in the deep Cambrian-Ordovician sandstone aquifer system, which can extend beyond state boundaries. Depicting some shallow, unconsolidated aquifers also requires a simultaneous simulation of the deep sandstone to account for flow exchange between units. This is because the low-permeable stratigraphic units (aquitards) overlying the sandstone aquifers are absent over large areas of northern Illinois or are locally punctured by wells with long, open intervals. To capture these complex flow pathways, the three-dimensional IGWFM explicitly simulates all geologic materials from the land surface to the impermeable Pre-Cambrian crystalline bedrock. The IGWFM does not currently include a groundwater flow simulation of the southern portion of the state where the deep basin sandstones are highly saline and not used for water supply. Incorporating the shallow aquifers in the southern portion of the state into the IGWFM is a long-term goal. The primary datasets currently incorporated into IGWFM include surface water elevations, annual groundwater withdrawals, well information such as open intervals, geologic 2 surfaces, measured water levels, and aquifer properties inferred from previous modeling studies. These datasets are input at their best available spatial and temporal resolutions, allowing for the development of refined local-scale models. Such local-scale models are essential for simulating groundwater-surface water interactions, well interference, and contaminant transport. Major local-scale models already exist for the Mahomet Aquifer, Kane County, and McHenry County. The IGWFM can address a number of water supply planning questions, particularly the impacts of historic, modern, and future high-capacity groundwater withdrawals on heads and groundwater discharging to surface waters. In addition, where detailed geologic information of the shallow aquifers is available, the IGWFM can also simulate the subsurface migration of point (e.g., volatile organic compounds) and nonpoint (e.g., chloride and nitrate) contaminants.published or submitted for publicationis peer reviewedOpe

    The Ursinus Weekly, November 7, 1974

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    The Great Pumpkin comes to U.C. ā€¢ Course Directory Catalogue Committee formed by U.S.G.A. ā€¢ Antigone is ProTheatre\u27s production ā€¢ Union does it again ā€¢ Criminal law featured as Forum topic ā€¢ Letters to the editor: Epitaph on an Ursinus transfer ā€¢ Pages from Ursinus past: A legend ā€¢ Perusing Pfahler\u27s pigeons ā€¢ New Economics head ā€¢ Equus reviewed ā€¢ Concerts: Bizarre and sublime ā€¢ Record review ā€¢ Nate DuPree: Can a black man find happiness at Ursinus? ā€¢ Martha Franklin: A half century of service to our students and campus ā€¢ Readin\u27, ritin\u27 and new math ā€¢ Introducing campus leaders ā€¢ Football wrapup: Swarthmore; Widener ā€¢ Hockey teams win the big games! ā€¢ Harriers 6-4 on seasonhttps://digitalcommons.ursinus.edu/weekly/1024/thumbnail.jp
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