9 research outputs found

    Advances in plastic and recontructive surgery

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    Combined Cranio-orbital Surgery for Extensive Malignant Neoplasms of the Orbit

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    Treatment Options for Exposed Calvarium Due to Trauma and Burns

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    Wounds involving the calvarium secondary to trauma or burns are rare. However, they can present with challenging potential clinical sequelae. A wide variety of reconstructive options have evolved over the last century. Technical aspects have progressively improved as well over time. For proper surgical restoration of function and cosmesis reconstructive surgeons must have a detailed understanding of both the scalp and skull anatomy. Several factors such as etiology of the injury, including whether or not calvarial bone defects exists or simply soft tissue loss, as well as size, local tissue environment and patient comorbidities play major roles in appropriate choice for reconstruction. Currently, there is no single treatment option for scalp or calvarial reconstruction after trauma or burns. However, reconstructive alternatives are constantly emerging with promising results

    To Serve Those Who Served: Advances in Plastic and Reconstructive Surgery During War and Peace

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    The industrialization of modern warfare dating back to WWI led to an increase in combat-related injuries with unprecedented levels of severity. The necessity of addressing the clinical challenges that ensued led to the emergence of modern reconstructive surgery and subsequently a robust healthcare initiative for veterans in the form of the Department of Veterans Affairs. In the following article, a literature review was conducted to examine the interplay between combat injuries, veterans' care, and reconstructive surgery. We found that the relationship between military trauma and reconstructive surgery has led to an increase in survival rates and advances in mass casualty response while allowing the survivors to maintain a high quality of life. The relationship between the Veterans Affairs hospitals and plastic surgery has only strengthened over time as these hospitals play a major role in training the next generation of plastic surgeons throughout the nation. It is imperative to maintain this cooperative relationship to ensure a high level of care for our veterans and a comprehensive training experience for plastic surgery residents

    Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism

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    Cherubism (MIM 118400) is an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws(1) followed by development of fibrous tissue masses, which causes a characteristic facial swelling. Here we describe seven mutations in the SH3-binding protein SH3BP2 (MIM 602104) on chromosome 4p16.3 that cause cherubism.Harvard Univ, Sch Med, Harvard Forsyth Dept Oral Biol, Harvard Sch Dent Med, Boston, MA USAHarvard Univ, Sch Med, Forsyth Inst, Boston, MA USAHarvard Univ, Sch Med, Dept Cell Biol, Boston, MA USAUniversidade Federal de São Paulo, EPM, Campinas, SP, BrazilSOBRAPAR, Inst Cirug Plast Craniofacial, Campinas, SP, BrazilHumboldt Univ, Inst Med Genet, Sch Med, Berlin, GermanyTampa Craniofacial Ctr, Tampa, FL USAUniv Calif Davis, Sacramento, CA 95817 USASo Maine Oral & Maxillofacial Surg, S Portland, ME USAUniv Copenhagen, Sch Dent, Dept Pediat Dent, Copenhagen, DenmarkUniversidade Federal de São Paulo, EPM, Campinas, SP, BrazilWeb of Scienc
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