236 research outputs found
Three Voices at Basel
Herbert Haag\u27s article discusses the outcome of the 1958 conference that was sponsored by the Christlich-judische Arbeitsgemeinschaft der Schweiz and attended by various Protestant, Catholic and Jewish scholars for the purpose of addressing the theme, Salvation present and salvation expected, according to both the Christian and the Jewish traditions
Three Voices at Basel
Herbert Haag\u27s article discusses the outcome of the 1958 conference that was sponsored by the Christlich-judische Arbeitsgemeinschaft der Schweiz and attended by various Protestant, Catholic and Jewish scholars for the purpose of addressing the theme, Salvation present and salvation expected, according to both the Christian and the Jewish traditions
Jesus and His People\u27s Traditions
An outline of the various Jewish traditions followed by Jesus. Translated from the German by Helga Croner
Dendritic polyglycerol nanoparticles show charge dependent bio-distribution in early human placental explants and reduce hCG secretion
A thorough understanding of nanoparticle bio-distribution at the feto-maternal
interface will be a prerequisite for their diagnostic or therapeutic
application in women of childbearing age and for teratologic risk assessment.
Therefore, the tissue interaction of biocompatible dendritic polyglycerol
nanoparticles (dPG-NPs) with first- trimester human placental explants were
analyzed and compared to less sophisticated trophoblast-cell based models.
First-trimester human placental explants, BeWo cells and primary trophoblast
cells from human term placenta were exposed to fluorescence labeled, ∼5 nm
dPG-NPs, with differently charged surfaces, at concentrations of 1 µM and 10
nM, for 6 and 24 h. Accumulation of dPGs was visualized by fluorescence
microscopy. To assess the impact of dPG-NP on trophoblast integrity and
endocrine function, LDH, and hCG releases were measured. A dose- and charge-
dependent accumulation of dPG-NPs was observed at the early placental barrier
and in cell lines, with positive dPG-NP-surface causing deposits even in the
mesenchymal core of the placental villi. No signs of plasma membrane damage
could be detected. After 24 h we observed a significant reduction of hCG
secretion in placental explants, without significant changes in trophoblast
apoptosis, at low concentrations of charged dPG-NPs. In conclusion, dPG-NP’s
surface charge substantially influences their bio-distribution at the feto-
maternal interface, with positive charge facilitating trans-trophoblast
passage, and in contrast to more artificial models, the first-trimester
placental explant culture model reveals potentially hazardous influences of
charged dPG-NPs on early placental physiology
The no-signaling condition and quantum dynamics
We show that the basic dynamical rules of quantum physics can be derived from
its static properties and the condition that superluminal communication is
forbidden. More precisely, the fact that the dynamics has to be described by
linear completely positive maps on density matrices is derived from the
following assumptions: (1) physical states are described by rays in a Hilbert
space, (2) probabilities for measurement outcomes at any given time are
calculated according to the usual trace rule, (3) superluminal communication is
excluded. This result also constrains possible non-linear modifications of
quantum physics.Comment: 4 page
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