Reconstructive Surgical Repair of a Forth Degree Iatrogenic Burn in a Dog

Background: Burns are uncommon in small animal surgery routine and represents a real therapeutic challenge. Skin can be affect in different degrees of deepness as superfcial, partial thickness, full thickness and full thickness affecting underlying tissues. Each degree has individual features. Progression through degrees can occur in the frst 24 h or if treatment is inadequate. This paper aims to describe therapeutic approach and surgical technique to treat a huge dorsal iatrogenic thermal burn injury. Case: A 4-year-old female German Shepard was referred to veterinary hospital after 11 days of elective ovariosalpingohisterectomy. The patient presented a severe skin injury with crusts, eschars, purulent discharge and myiasis on dorsal cervical, thoracic and lumbar region. Beside severity of the wound, animal present good general status and normal vital signs. Complete blood count and biochemical analysis were within normal ranges. Histopathologic analysis of a wound tissue sample revealed the presence of coagulation necrosis and inflammatory response. The absence of traumatic events, histopathologic result and wound features increased suspicious of an iatrogenic burn injury from a poorly regulated thermal mattress used during surgical intervention. “Rule of Nines” was estimated as 25% of total body surface area. Systemic antibiotics and topical treatment with 0.05% chlorhexidine digluconate and 2.5% silver sulfadiazine ointment followed by wet-wet bandage was performed after initial surgical debridement. Muscle and vertebral bone explosion were evident. Topical treatment with Silver Sulfadiazine and chlorhexidine persisted twice daily until granulation tissue formation. Pain killers and sedation were often necessary during bandage changes. At 65th day proceeded to en bloc excision of scar tissue and surgical reconstruction with skin advancement and recruitment technique. Tie-over dressing was applied to cover the fnal wound. After 14 days animal received hospital discharge, and was assessed bi-weekly for 60 days. Discussion: Besides great extension of the burn injury, patient’s age, absence of systemic involvement and fluid therapy or critical care the prognosis was good. Modifed “rule of nine” are used to estimate wound size in dogs. The wound was classifed as forth degree or full thickness injury due to exposed muscular layer and bone. Early debridement, standard topical and systemic treatment protocol applied granted good recovery of wound bed. Due to be uncommon in small animal routine, main diagnosis and therapeutic recommendations for veterinary patients are based on human data. Systemic antimicrobial drugs are usually not recommended due to low concentration in burned tissues, however, prophylactic use was necessary due to highly infected tissues and possible bacterial absorption from devitalized tissues. Delayed primary closure technique was necessary due to highly infection site and extension, which turns surgical approach hard to perform. After formation of a granulation tissue bed for wound reconstruction, surgical treatment was performed. Surgical reconstruction is indicated in large full thickness defects and for better cosmetic appearance. The correct use and regulation of thermal mattress can avoid burns that can be life threatening. This case report rises the important concept that even low contact temperatures when persistent for long time can cause burn injuries. Keywords: thermal, mattress, injury, dogs, plastic

Osteosarcoma de tipo compuesto: relato de caso

  Osteosarcoma is considered the most common bone tumor in dogs, usually affecting the appendicular skeleton of animals adults or seniors with an average age of seven years. The etiology of canine appendicular osteosarcoma remains unknown. Some factors predispose the animals to the emergence of neoplasia, including: size, race and family. The tumor can be classified by macroscopic and radiological features in simple, compound, or pleomorphic. This article is a case report of osteosarcoma of the composite type with metastases in the pericardium, lung, pleura, intercostal muscles, liver and kidney in a dog breed Labrador Retriver. This presents the history of the animal, which together with the necropsy findings and histopathological examination confirmed the cause of death. We conclude that histopathological examination is an important tool for classify tumor depending on the cellular pattern and identifying the presence metastases in the different organs collected.El osteossarcoma es considerado el tumor óseo más común en perros, afecta principalmente el esqueleto apendicular de animales adultos o seniles, con edad media de siete años. La etiología del osteossarcoma apendicular canino aún permanece desconocida. Algunos factores predisponen al surgimiento de esta neoplasia, tales como: tamaño, raza y familia. La neoplasia puede ser clasificada por las características macroscópicas y radiológicas en simple, compuesta o pleomórfica. El presente artículo es un relato de caso de osteossarcoma de tipo compuesto con metástasis en pericardio, pulmón, pleura, músculos intercostales, hígado y riñones en una perra de raza Labrador Retriver. En este, se describe la historia clínica del animal, que junto con las alteraciones observadas en la necropsia y el examen histopatológico confirmaron la causa de la muerte. Se concluye que el examen histopatológico es importante para clasificar el tumor por su patrón celular e identificar la presencia de metástasis en los diferentes órganos colectados

Intermuscular Lipoma in Dogs

Background: Lipoma is a benign tumor composed of mature adipose tissue commonly found in subcutaneous tissues. However, eventually, lipomas may be located between the muscle fasciae being classifed as intermuscular lipomas. Complete surgical resection of the tumor mass is indicated as a treatment of affected patients.This report describes fve cases of intermuscular lipoma in dogs, due to the scarcity of data in the literature and lipoma relative importance in the clinical and surgical routine.Case: Five dogs were presented with a history of a large volume in the limbs with progressive growth, suggesting the presence of neoplasia. The frst step was to conduct anamnesis, when the owner reported slow growth, absence of pain, limping and licking of site. No other change was observed upon physical examination. Complete blood count (CBC) as well as liver assessment (FA) and renal (creatinine) were performed in all patients, and the results showed no changes. Fine needle aspiration cytology (FNAC) was performed and showed cells from adipose tissue, followed by histopathological examination of the lesions. Histopathological examination after incisional biopsy of the tumors showed malignancy-freetissue, composed of adipocytes without atypia, interspersed with fbrovascular stroma, confrming the lipoma diagnosis.Intermuscular lipomas were diagnosed in fve dogs with a history of a large volume in the limbs with progressive growth; all of them underwent bloc resection of the tumors. In all cases, the intermuscular lipomatous tumors were well-circumscribed and easily isolated from the tissues.Discussion: Although lipomas are relatively common in older dogs, especially in the subcutaneous tissue, intermuscular subtype is rare in veterinary medicine, which justifes the report of these cases. Intermuscular lipomas account for only 0.3% of the occurrences in human medicine. Morphologically described as tumors of slow and progressive evolution, typically reaching sizes up to 2 cm in humans, the particular cases of tumor masses greater than 5 cm are called giant lipomas. Theslow development of intermuscular lipomas has also been described in domestic animals by, thus corroborating the clini cal history in this work. The intermuscular septum is considered as the origin of intermuscular lipoma, with subsequent development of the adipose tissue between adjacent muscle bundles, thus, resulting usually in well-circumscribed mass of easy surgical divulsion. The morphological characteristics of the resected lipomas, as well as the simple surgical technique corroborate descriptions in the literature. Intermuscular lipomas consist of a challenging diagnosis despite attracting little attention from surgeons. The possibility of the mass being malignant, such as liposarcoma, should also be consideredsince the clinical symptoms consist of swelling of the deep soft tissues. The diagnosis for all these patients was obtained by histopathological examination, since the simple observation of the clinical fndings alone does not support the tumor diagnosis. Lipoma and liposarcoma should be differentiated by cytological and histopathological evaluations of the neoplasia, whereas infltrative lipomas can be diagnosed based on diagnostic imaging methods or even on the fndings during surgery. In this report, specifcally, the fndings during surgery contributed to the differentiation between infltrative and intermuscular lipoma, while for malignancy rating all patients underwent cytological and histopathological evaluations asindicated in the literature. In conclusion, this study demonstrated that complete resection of intermuscular lipoma proved to be an effective treatment to cure the patients.Keywords: benign neoplasm, surgery, resection of intermuscular, canine

Tratamiento Quirúrgico En La Corrección De Prolongamiento De Paladar Blando Y Estenosis Nasal En Un Canino

Brachycephalic dogs are predisposed to alterations in the tissues of the upper respiratory system, such as: nostrils stenosis, elongated soft palate, laryngeal saccules eversion and laryngeal collapse. This article describes a male, boxer, dog, nine months of age that clinical examination showed mucosal cyanotic, nostrils stenosis, inspiratory dyspnea and respiratory auscultation rattle noisily.Laryngeal examination was performed which showed the soft palate to theepiglottis overlap by about one centimeter. The soft palate showed thickenedwith rough edges and inflamed. Due to nasal stenosis and the extension of thepalate was decided the surgical resection of the soft palate and surgicalcorrection of stenotic nares.Los perros braquiocefálicos están predispuestos a sufrir cambios en los tejidosdel sistema respiratorio superior, tales como: la estenosis de las fosas nasales,prolongamiento del paladar blando, eversión de los sáculos laríngeos y colapsolaríngeo. En este artículo se describe el caso de un perro de raza bóxer,macho, con nueve meses de edad que durante el examen clínico presentómucosas cianóticas, estenosis de las fosas nasales, disnea inspiratoria,estertores pulmonares y auscultación respiratoria ruidosa. Se realizó examenlaríngeo mostrando que el paladar blando se superpone a la epiglotis enalrededor de un centímetro. El paladar blando estaba espesó y con leextremidad asperea e inflamada. Debido a la estenosis nasal y la extensión delpaladar se decidió la resección quirúrgica del paladar blando y de la correcciónde las narinas estenósadas

Tratamiento quirúrgico de discopatía cervical relato de caso

  The most common cause of spinal cord injury in dogs is intervertebral disc disease (IVDD) or herniated disc, intervertebral disc disease is caused by disc extrusion into the spinal canal. The following is a case report of an IVDD in adult dog that said neck stiffness and intense pain for cervical movement .Cervical spine radiographs were taken in lateral-lateral projection, observing reduction in the intervertebral space between C3 and C4. Instituted drug treatment without satisfactory outcome. In order to determine the exact location of injury the animal was subject to positive contrast radiological examination of spinal canal (myelography), witch where can display the flow lockout contrast between C3 and C4. The animal was referred for spinal decompression surgery for ventral fenestration technique. Removed the calcified intervertebral disc allowing the spinal cord assume normal position. Conclude that surgical treatment was successful, with a significant clinical evolution; during neurological assessment, the animal was found alert, active, without neck pain, or difficulty in movement.  La causa más común de lesión en la médula espinal de los perros es la enfermedad de disco intervertebral (EDIV) o hernia de disco; esta discopatía intervertebral es causada por la extrusión del material discal en el interior del canal medular. El siguiente es un relato de caso de EDIV en un perro adulto que manifestó rigidez cervical e intenso dolor al movimiento cervical. Radiografías de la región cervical fueron tomadas en proyección latero-lateral, observando reducción del espacio intervertebral entre C3 y C4. Fui instituido tratamiento farmacológico sin evolución satisfactoria. Con el fin de determinar laubicación exacta de la lesión, el animal fue sometido a examen radiológico de contraste positivo del canal medular (mielografía), evidenciando bloqueo del flujo de contraste entre C3 y C4. El animal fue encaminado para cirugía de descomprensión medular por la técnica de fenestración ventral. Se removió el disco calcificado del espacio intervertebral permitiendo a la médula asumir su posición normal. Se concluye que el tratamiento quirúrgico fue satisfactorio, con una evolución clínica significativa; durante lavaloración neurológica, el animal se observó alerta, activo, sin manifestar dolor cervical, ni dificultad en sus movimientos

Right Laparoscopic Adrenalectomy in a Bitch

Background: The medical procedure of Laparoscopic adrenalectomy is common in human medicine; however, this is not true in veterinary medicine, where it isperformed rarely. The current treatment of choice for adrenal neoplasms is total adrenalectomy, unless there is a pre-operativediagnosis of metastasis that precludes surgery. The laparoscopic approach option becomes an interesting alternative because, through this technique,it has shown good results. In this report, we demonstrate the experience of a case in which we performed unilateral laparoscopic right adrenalectomy, without caudalvena cava invasion, in a dogsuffering from hyperadrenocorticism caused by adrenocortical carcinoma.Case: A 9-year-old beagle bitch, 12 kg in weight, showedpolyphagia, polydipsia, polyuria, pendular abdomen, thin and dark skin, lumbar alopecic areas and lethargy. The team carried out Complete Blood Count (CBC), blood chemistry (liver and renal functions) and urine sampling by cystocentesis for urinalysis and bacterial culture. All exams had normal results, except for ALP, which reached levels higher than 150 UIL-1. On abdominal radiographic examination, we noted mild adrenal enlargement, and by ultrasonography, it was possible to identify adrenal asymmetry and right adrenal enlargement (2.8x2x2.15 cm) in relation to the left gland (2x1x1.5 cm). As a treatment for adrenal neoplasm-dependent HAC,we recommended the execution of total right adrenalectomy execution. The videosurgery used four accesses arranged in the right hypogastric region; the diameters were 10 (two), 5, and 3mm. The adrenal gland was carefully dissected with the aid of laparoscopic forceps; during the intraoperative period, there was a small laceration of the abdominal phrenic vein that resulted in bleeding, which was overcome with two titanium clips. The dog had an excellent recovery, and the teamdischarged it 48 h after the procedure. The signs of hyperadrenocorticism disappeared about two weeks after surgery. One year after having the procedure, the animal remainswell and has no signs of tumor recurrence or Cushing’s syndrome.Discussion: The choice laparoscopic approach provided less invasiveness in surgical access, reduced animal convalescence, and provided image magnifcation for the more accurate dissection of the adrenal gland. Some reports that middle-aged to older bitches were the most predisposed to present adrenal neoplasm-dependent HAC, and generally, in unilateral form, characteristics which are presented in this report. Among the clinical signs and observed in this report, are polydipsia, polyphagia, tachypnea, alopecia, and skin hyperpigmentation. That recommended the low-dose dexamethasone suppression test to diagnose Cushing’s syndrome and the endogenous ACTH test to distinguish hypophysary from adrenocorticotrophic HAC. The same tests were performed in the case reported here, as these are also important to establish the fnal diagnosisand refer the total adrenalectomy realization. In the current case report, access to the right hypogastric region using four videosurgery portals provided good surgical access. Towards the hospital convalescence time, the animal was discharged early, just 48 h post-operatively; remission of HAC clinical signs occurredwithin three weeks, and the survival alreadyreached 12 months.To the best of the authors’ knowledge, this is the frst successful case of total right adrenalectomy without caudal vena cava invasion via the laparoscopic route as treatment for adrenocortical carcinoma in the national literature.Keywords: adrenal gland, neoplasm, videosurgery, dogs

Criocirugía en el tratamiento de carcinoma de células escamosas en perro

Squamous cell carcinoma (SCC) is one of most common malignant skin tumors in dogs, locally invasive and can affect dermis and hypodermis. Older animals are usually affects and no racial predisposition. Productive, friable and papillary growth tumor can have, or may be erosive lesion formation with ulcerated an anywhere of skin, trunk are the most frequent local, leg, scrotum, lips and bed nail too frequently affect. Treatment by surgical excision with wide margins and cryosurgery can be performed and associated with chemotherapy and radiotherapy. The objective of this report is describe effective treatment in a mix breed male canine, aged six years and weighing 22 kg with cytologic and histopathologic diagnosis of squamous cell carcinoma in the pelvic limb, which were initially held four sessions of cryosurgery and after the recovery of the patient, four sessions of intravenously chemotherapy was performed. We conclude that therapy with cryosurgery was satisfactory against this neoplasm.El carcinoma de células escamosas (CCE) es uno de los tumores cutáneos malignos más comunes en perros; son localmente invasivos y pueden comprometer la dermis e hipodermis. Generalmente afecta animales seniles y no existe predisposición por raza. El tumor puede realizar un crecimiento productivo, friable y papilar; o puede ser erosivo con formación de lesión ulcerada. Ocurre en cualquier lugar de la piel, siendo los sitios con más frecuencia: el tronco, la pierna, el escroto, los labios y el lecho ungueal. El tratamiento por la escisión quirúrgica con margen amplia y la criocirugía pueden ser realizados y asociados al tratamiento quimioterapéutico y la radioterapia. El objetivo de este relato es describir el tratamiento eficaz en un canino mestizo, macho, con seis años de edad y 22 kg de peso vivo, con diagnóstico cito e histopatológico de carcinoma de células escamosas en el miembro pélvico, donde fueron realizadas inicialmente cuatro sesiones de criocirugía y después de la recuperación del paciente, se efectuó la quimioterapia antineoplásica por vía intravenosa por cuatro sesiones. De acuerdo con los resultados obtenidos y después de 30 meses de terapia se concluye que la criocirugía fue una técnica eficaz para la cura de este tipo de neoplasia..

Micropapillary carcinoma in a dog: case report

Mammary neoplasms in female dogs present a high incidence. Several histological types are observed, among them, micropapillary carcinoma is considered one of the most aggressive because it is related to vascular invasion, metastases and low survival time. Aimed to describe a case of micropapillary breast carcinoma, with cutaneous metastasis, in a dog. A canine, female, 14 years old, 8kg, not defined breed, uncastrated, nulliparous, with pseudocyesis and no contraceptives administration history was attended at the Veterinary Reproduction and Obstetrics Service from "Governador Laudo Natel” Hospital, FCAV, UNESP, Jaboticabal, presenting a breast ulcerated nodule, with one month estimated evolution. After stabilization and preoperative exams, radical unilateral mastectomy and ipsilateral axillary and inguinal lymphadenectomy were performed. Histopathologic diagnosis revealed micropapillary carcinoma and free surgical margins from neoplasm, however, there were metastasis in both lymph nodes. The tutors did not adhere to antineoplastic chemotherapy. In 60th post-surgical day, there was inflammatory reaction in the surgical scar region, with small cutaneous ulceration, where the elastogram  revealed  rigidity and shear velocity of 7.84m/s. Skin biopsy revealed metastasis of micropapillary breast carcinoma. There was progression of ulcerations, compromising animal’s welfare and its physiological activities, when on the 110th post-surgical day, it was decided to euthanize the patient.  The correct diagnosis and knowledge of tumor biological behavior are importants points to choose the correct treatment. The adjuvant chemotherapy treatment can impact on average survival time and ARFI elastography is an accurate predictor of rapid and non-invasive diagnosis of micropapillary carcinoma recurrence.Mammary neoplasms in female dogs have a high incidence. Among the several histological types observed, micropapillary carcinoma is considered one of the most aggressive due to vascular invasion, metastases, and short survival time. The present objective was to describe a case of mammary gland micropapillary carcinoma, with cutaneous metastasis, in a dog. A 14-year-old intact nulliparous mixed-breed bitch, weighing 8kg, with a history of pseudocyesis and no history of contraceptive administration, presented to the Veterinary Reproduction and Obstetrics Service from "Governador Laudo Natel” Hospital, FCAV, UNESP, Jaboticabal, with an ulcerated nodule in the mammary gland for approximately one month. After stabilization of clinical parameters and preoperative exams, a radical unilateral mastectomy and ipsilateral axillary and inguinal lymphadenectomy were performed. Histopathology revealed micropapillary carcinoma with clear surgical margins, however, there were metastases in both lymph nodes. Antineoplastic chemotherapy was refused by the owners. On the 60th day after surgery, there was an inflammatory reaction in the surgical scar region, with a small cutaneous ulceration, where elastography showed rigidity and shear velocity of 7.84m/s. Skin biopsy revealed metastasis of the micropapillary carcinoma. Even with continued treatment since the patient was first examined, the ulcerations progressed, compromising the animal’s welfare and physiological activities, and on the 110th day after surgery, euthanasia was decided on. A correct diagnosis and knowledge of tumor biological behavior are important points for choosing the correct treatment. Acoustic Radiation Force Image (ARFI) elastography has been shown to be a fast and non-invasive diagnostic method for detection of recurrent micropapillary carcinoma

Diagnosis, Prognosis and Treatment of Canine Cutaneous and Subcutaneous Mast Cell Tumors

Mast cell tumors (MCTs) are hematopoietic neoplasms composed of mast cells. It is highly common in dogs and is extremely important in the veterinary oncology field. It represents the third most common tumor subtype, and is the most common malignant skin tumor in dogs, corresponding to 11% of skin cancer cases. The objective of this critical review was to present the report of the 2nd Consensus meeting on the Diagnosis, Prognosis, and Treatment of Canine Cutaneous and Subcutaneous Mast Cell Tumors, which was organized by the Brazilian Association of Veterinary Oncology (ABROVET) in August 2021. The most recent information on cutaneous and subcutaneous mast cell tumors in dogs is presented and discussed