1,062 research outputs found
Lifestyle, dietary factors and antibody levels to oral bacteria in cancer-free participants of a European cohort study
BackgroundâIncreasing evidence suggests that oral microbiota play a pivotal role in chronic diseases, in addition to the well-established role in periodontal disease. Moreover, recent studies suggest that oral bacteria may also be involved in carcinogenesis; periodontal disease has been linked several cancers. In this study, we examined whether lifestyle factors have an impact on antibody levels to oral bacteria.
MethodsâData on demographic characteristics, lifestyle factors, and medical conditions were obtained at the time of blood sample collection. For the current analysis, we measured antibody levels to 25 oral bacteria in 395 cancer-free individuals using an immunoblot array. Combined total immunglobin G (IgG) levels were obtained by summing concentrations for all oral bacteria measured.
ResultsâIgG antibody levels were substantially lower among current and former smokers (1697 and 1677 ng/mL, respectively) than never smokers (1960 ng/mL; p-trend = 0.01), but did not vary by other factors, including BMI, diabetes, physical activity, or by dietary factors, after adjusting for age, sex, education, country and smoking status. The highest levels of total IgG were found among individuals with low education (2419 ng/mL).
ConclusionsâOur findings on smoking are consistent with previous studies and support the notion that smokers have a compromised humoral immune response. Moreover, other major factors known to be associated with inflammatory markers, including obesity, were not associated with antibody levels to a large number of oral bacteria
A precision study of the fine tuning in the DiracNMSSM
Recently the DiracNMSSM has been proposed as a possible solution to reduce
the fine tuning in supersymmetry. We determine the degree of fine tuning needed
in the DiracNMSSM with and without non-universal gaugino masses and compare it
with the fine tuning in the GNMSSM. To apply reasonable cuts on the allowed
parameter regions we perform a precise calculation of the Higgs mass. In
addition, we include the limits from direct SUSY searches and dark matter
abundance. We find that both models are comparable in terms of fine tuning,
with the minimal fine tuning in the GNMSSM slightly smaller.Comment: 20 pages + appendices, 10 figure
Report from Mongolia â How much do we know about the incidence of rare cases in less developed countries: a case series
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Inclusive J/Ï production at mid-rapidity in pp collisions at âs = 5.02 TeV
Inclusive J/Ï production is studied in minimum-bias proton-proton collisions at a centre-of-mass energy of s = 5.02 TeV by ALICE at the CERN LHC. The measurement is performed at mid-rapidity (|y| < 0.9) in the dielectron decay channel down to zero transverse momentum pT, using a data sample corresponding to an integrated luminosity of Lint = 19.4 ± 0.4 nbâ1. The measured pT-integrated inclusive J/Ï production cross sec- tion is dÏ/dy = 5.64 ± 0.22(stat.) ± 0.33(syst.) ± 0.12(lumi.) ÎŒb. The pT-differential cross section d2Ï/dpTdy is measured in the pT range 0â10 GeV/c and compared with state-of- the-art QCD calculations. The J/Ï ăpTă and ăpT2ă are extracted and compared with results obtained at other collision energies. [Figure not available: see fulltext.]
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Measurement of Î (1520) production in pp collisions at âs=7TeV and pâPb collisions at âsNN=5.02TeV
The production of the Î (1520) baryonic resonance has been measured at midrapidity in inelastic pp collisions at s=7TeV and in pâPb collisions at sNN=5.02TeV for non-single diffractive events and in multiplicity classes. The resonance is reconstructed through its hadronic decay channel Î (1520) â pK - and the charge conjugate with the ALICE detector. The integrated yields and mean transverse momenta are calculated from the measured transverse momentum distributions in pp and pâPb collisions. The mean transverse momenta follow mass ordering as previously observed for other hyperons in the same collision systems. A Blast-Wave function constrained by other light hadrons (Ï, K, KS0, p, Î) describes the shape of the Î (1520) transverse momentum distribution up to 3.5GeV/c in pâPb collisions. In the framework of this model, this observation suggests that the Î (1520) resonance participates in the same collective radial flow as other light hadrons. The ratio of the yield of Î (1520) to the yield of the ground state particle Î remains constant as a function of charged-particle multiplicity, suggesting that there is no net effect of the hadronic phase in pâPb collisions on the Î (1520) yield
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Measurement of electrons from heavy-flavour hadron decays as a function of multiplicity in p-Pb collisions at âsNN = 5.02 TeV
The multiplicity dependence of electron production from heavy-flavour hadron decays as a function of transverse momentum was measured in p-Pb collisions at sNN = 5.02 TeV using the ALICE detector at the LHC. The measurement was performed in the centre-of-mass rapidity interval â1.07 < ycms< 0.14 and transverse momentum interval 2 < pT< 16 GeV/c. The multiplicity dependence of the production of electrons from heavy-flavour hadron decays was studied by comparing the pT spectra measured for different multiplicity classes with those measured in pp collisions (QpPb) and in peripheral p-Pb collisions (Qcp). The QpPb results obtained are consistent with unity within uncertainties in the measured pT interval and event classes. This indicates that heavy-flavour decay electron production is consistent with binary scaling and independent of the geometry of the collision system. Additionally, the results suggest that cold nuclear matter effects are negligible within uncertainties, in the production of heavy-flavour decay electrons at midrapidity in p-Pb collisions. [Figure not available: see fulltext.
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