Socioeconomic Achievement Among Arab Immigrants in the USA: The Influence of Region of Origin and Gender

Based on the Integrated Public Use Microdata Series (IPUMS) data derived from 2001–2013 samples of the American Community Surveys, we examine the impact of region of origin and gender on socioeconomic achievement variation among Arab immigrants in the USA. Region of origin includes North Africa (Algeria, Egypt, Libya, Morocco, and Sudan), Levant (Jordan, Lebanon, Syria, and Iraq), and the Arabian Peninsula (Bahrain, Qatar, United Arab Emirates, Oman, Saudi Arabia, and Yemen). This examination is particularly important given the prevailing scholarly consensus that Arab immigrants are collectively portrayed as socioeconomically successful. Our analyses suggest two key findings. First, we find that region of origin is not a consistent predictor of earnings. While Arab immigrants from North Africa earned significantly less than those from the Levant, this was only true for males. No significant effect is found for region of origin in all other comparisons (both overall and when the analysis is restricted to males or females). Second, and by contrast, gender, net of other variables is a powerful predictor of earnings (both within regions and across regions)

Stenosis coexists with compromised α1-adrenergic contractions in the ascending aorta of a mouse model of Williams-Beuren syndrome

Williams-Beuren syndrome (WBS) is a rare disorder caused by a heterozygous deletion of 26-28 contiguous genes that affects the brain and cardiovascular system. Here, we investigated whether WBS affects aortic structure and function in the complete deletion (CD) mouse model harbouring the most common deletion found in WBS patients. Thoracic aortas from 3-4 months-old male CD mice and wild-type littermates were mounted in wire myographs or were processed for histomorphometrical analysis. Nitric oxide synthase (NOS) isoforms and oxidative stress levels were assessed. Ascending aortas from young adult CD mice showed moderate (50%) luminal stenosis, whereas endothelial function and oxidative stress were comparable to wild-type. CD mice showed greater contractions to KCl. However, α1-adrenergic contractions to phenylephrine, but not with a thromboxane analogue, were compromised. Decreased phenylephrine responses were not affected by selective inducible NOS blockade with 1400 W, but were prevented by the non-selective NOS inhibitor L-NAME and the selective neuronal NOS inhibitor SMTC. Consistently, CD mice showed increased neuronal NOS expression in aortas. Overall, aortic stenosis in CD mice coexists with excessive nNOS-derived NO signaling that compromises ascending aorta α1-adrenergic contractions. We suggest that increased neuronal NOS signaling may act as a physiological 'brake' against the detrimental effects of stenosis.This work was supported by Ministerio de Ciencia e Innovación [[SAF2014-56111-R to FJA] and [SAF2016-78508-R (AEI/MINEICO/FEDER, UE) to VC]]; and Generalitat de Catalunya [2017-SGR-645 to FJA]