15 research outputs found
Diets containing sea cucumber (Isostichopus badionotus) meals are hypocholesterolemic in young rats
Peer reviewedPublisher PD
Directional orientation of reproductive tissue of Eulychnia breviflora (Cactaceae) in the hyperarid Atacama Desert
A dot-ELISA using a partially purified cathepsin-L-like protein fraction from Taenia solium
Isolation of High-Quality Total RNA from Chinese Fir (Cunninghamia lanceolata (Lamb.) Hook)
Fungal biological resources to support international development: challenges and opportunities
Investigating the floral and reproductive biology of the endangered microendemic cactus Uebelmannia buiningii Donald (Minas Gerais, Brazil)
GluN3A NMDA receptor subunits: more enigmatic than ever?
Non-conventional N-methyl-d-aspartate receptors (NMDARs) containing GluN3A subunits have unique biophysical, signalling and localization properties within the NMDAR family, and are typically thought to counterbalance functions of classical NMDARs made up of GluN1/2 subunits. Beyond their recognized roles in synapse refinement during postnatal development, recent evidence is building a wider perspective for GluN3A functions. Here we draw particular attention to the latest developments for this multifaceted and unusual subunit: from finely timed expression patterns that correlate with plasticity windows in developing brains or functional hierarchies in the mature brain to new insight onto presynaptic GluN3A-NMDARs, excitatory glycine receptors and behavioural impacts, alongside further connections to a range of brain disorders.Work in the authors´ laboratory is funded by grants from the Agencia Española de Investigación (SAF2016-80895-R, PID2019_111112RB_I00), Generalitat Valenciana (PROMETEO 2019/020) (to I.P.O.) and Severo-Ochoa Excellence Award (SEV-2017-0723). M.J.C.D. was funded by a predoctoral fellowship from the Fundación Tatiana Pérez de Guzmán el Bueno, FEBS and IBRO short-term fellowships, and O.C. by Severo-Ochoa and Marie Curie Postdoctoral fellowships.Peer reviewe