36 research outputs found

    The effects of refining steps on kilka (Clupeonella delicatula) fish oil quality

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    Kilka fish are known as the main industrial and pelagic species of Iran that are captured abundantly in the southern Caspian Sea. This study was conducted to survey the effectiveness of refinement steps on Kilka (Clupeonella delicatula) crude oil quality and fatty acid profiles. Neutralization, bleaching, winterization and deodorization were performed on crude oil with deodorization done under two different conditions of A: at 180˚C for 120 min and B: at 140˚C for 240 min. During refinement, peroxide value (PV) significantly decreased from 7.66 meq/kg in crude oil to 0.5 in deodorized oil A and to 0.21 in deodorized oil B (p<0.05). Significant reduction in free fatty acids (FFA) was recorded from 0.86% oleic acid in crude oil to 0.15% in deodorized oil A and to 0.33% in deodorized oil B (p<0.05). N-3 fatty acids content and fatty acids composition were determined by GC-FID and n-3 fatty acids content increased from 18.74% in crude oil to 21.58% in deodorized oil A and to 21.75% in deodorized oil B. The red color in oil significantly decreased from 5.4 to 0.4 and 0.5 in deodorized oil A and deodorized oil B, respectively (p<0.05). Results confirm that refinement steps improved oil quality and raised n-3 PUFA concentration and n-3/n-6, properly. Deodorization at 180˚C for 120 minutes (A) was more effective than deodorization at 140˚C for 240 minutes (B) in removing off flavors

    Contovir - A new adjuvant therapy in recurrent respiratory papillomatosis: A case study

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    Background: Contovir is a mixture of herbal extracts (Tanacetum vulgare, Rossa canina, Urtica dioica) that is supplemented with selenium. Objectives: This study aimed to add Contovir to the classic treatment of recurrent respiratory papillomatosis (RRP) in order to decrease the severity and extent of the disease, elongate the surgical intervals and improve the sense of patient well-being. Furthermore, we had to adjust the prescribed drug dosage, since there were no previous findings available. Patients and Methods: This is a case study of RRP patients treated with Contovir as an adjuvant to the classic treatment, from March 2011 to February 2013, at an academic tertiary hospital (Rasoul-e-Akram hospital). All patients underwent surgical removal of papilloma and then were prescribed Contovir. Disease severity was quantified based on Derkay�s staging system. Results: Eight patients were enrolled in this study. The extent and severity of the disease improved in six cases. One had no response, and the severity of disease increased in one patient. Patients with supraglottic lesions had better responses to Contovir adjuvant therapy. No immediate or long-term side effects were reported. Conclusions: Although Contovir has been found to be an advantageous adjuvant for RRP treatment, further studies are called for to verify these findings. © 2016, Iranian Red Crescent Medical Journal

    Contovir - A new adjuvant therapy in recurrent respiratory papillomatosis: A case study

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    Background: Contovir is a mixture of herbal extracts (Tanacetum vulgare, Rossa canina, Urtica dioica) that is supplemented with selenium. Objectives: This study aimed to add Contovir to the classic treatment of recurrent respiratory papillomatosis (RRP) in order to decrease the severity and extent of the disease, elongate the surgical intervals and improve the sense of patient well-being. Furthermore, we had to adjust the prescribed drug dosage, since there were no previous findings available. Patients and Methods: This is a case study of RRP patients treated with Contovir as an adjuvant to the classic treatment, from March 2011 to February 2013, at an academic tertiary hospital (Rasoul-e-Akram hospital). All patients underwent surgical removal of papilloma and then were prescribed Contovir. Disease severity was quantified based on Derkay�s staging system. Results: Eight patients were enrolled in this study. The extent and severity of the disease improved in six cases. One had no response, and the severity of disease increased in one patient. Patients with supraglottic lesions had better responses to Contovir adjuvant therapy. No immediate or long-term side effects were reported. Conclusions: Although Contovir has been found to be an advantageous adjuvant for RRP treatment, further studies are called for to verify these findings. © 2016, Iranian Red Crescent Medical Journal

    Precision measurements of differential cross sections and analyzing powers in elastic deuteron-deuteron scattering at 65 MeV/nucleon

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    We present measurements of differential cross sections and analyzing powers for the elastic 2H(d, d)d scat-tering process. The data were obtained using a 130 MeV polarized deuteron beam. Cross sections and spin observ-ables of the elastic scattering process were measured at the AGOR facility at KVI using two independent setups, namely BINA and BBS. The data harvest at setups are in excellent agreement with each other and allowed us to carry out a thor-ough systematic analysis to provide the most accurate data in elastic deuteron-deuteron scattering at intermediate energies. The results can be used to confront upcoming state-of-the-art calculations in the four-nucleon scattering domain, and will, thereby, provide further insights in the dynamics of three-and four-nucleon forces in few-nucleon systems

    National guidelines for cognitive assessment and rehabilitation of Iranian traumatic brain injury patients

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    Background: Individuals with moderate to severe traumatic brain injury (TBI) often have prolonged cognitive impairments, resulting in long-term problems with their real-life activities. Given the urgent need for evidence-based recommendations for neuropsychological management of Iranian TBI patients, the current work aimed to adapt eligible international guidelines for cognitive assessment and rehabilitation of the TBI patients in Iran. Methods: The project was led by an executive committee, under the supervision of the Iranian Ministry of Health and Medical Education (MOHME). Following a systematic literature search and selection process, four guidelines were included for adaptation. Clinical recommendations of the source guidelines were tabulated as possible clinical scenarios for 90 PICO clinical questions covering all relevant phases of care. After summing up the scenarios, our initial list of recommendations was drafted according to the Iranian patients� conditions. The final decision-making, with the contribution of a national interdisciplinary panel of 37 experts from across the country, was conducted in two rounds using online and offline survey forms (Round 1), and face-to-face and telephone meetings (Round 2). Results: A total of 63 recommendations in six sections were included in the final list of recommendations, among which 24 were considered as key recommendations. In addition, some of the recommendations were identified as fundamental, meaning that proper implementation of the other recommendations is largely dependent on their implementation. Conclusion: Iranian health policy makers and rehabilitation program managers are recommended to address some fundamental issues to provide the necessary infrastructure to set up an efficient cognitive rehabilitation service system. © 2020 Academy of Medical Sciences of I.R. Iran. All rights reserved

    The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

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    BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

    M‌O‌D‌I‌F‌I‌E‌D A‌P‌P‌L‌I‌C‌A‌T‌I‌O‌N O‌F M‌O‌D‌I‌F‌I‌E‌D E‌L‌E‌M‌E‌N‌T‌A‌L E‌L‌E‌M‌E‌N‌T‌S, B‌A‌S‌E‌D O‌N T‌H‌E C‌O‌N‌C‌E‌P‌T O‌F E‌N‌E‌R‌G‌Y, F‌O‌R A‌N‌A‌L‌Y‌Z‌I‌N‌G S‌T‌R‌U‌C‌T‌U‌R‌E‌S, I‌N T‌H‌E R‌A‌N‌G‌E O‌F S‌M‌A‌L‌L D‌E‌F‌O‌R‌M‌A‌T‌I‌O‌N‌S

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    I‌n t‌h‌i‌s p‌a‌p‌e‌r, a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d f‌o‌r l‌i‌n‌e‌a‌r a‌n‌a‌l‌y‌s‌i‌s o‌f s‌t‌r‌u‌c‌t‌u‌r‌e‌s b‌a‌s‌e‌d o‌n e‌n‌e‌r‌g‌y c‌o‌n‌c‌e‌p‌t i‌n t‌h‌e r‌a‌n‌g‌e o‌f s‌m‌a‌l‌l d‌e‌f‌o‌r‌m‌a‌t‌i‌o‌n‌s h‌a‌s b‌e‌e‌n d‌e‌v‌e‌l‌o‌p‌e‌d a‌n‌d i‌n‌t‌r‌o‌d‌u‌c‌e‌d a‌s m‌o‌d‌i‌f‌i‌e‌d a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d. T‌h‌i‌s m‌e‌t‌h‌o‌d c‌o‌n‌s‌i‌d‌e‌r‌s t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e a‌s a s‌e‌t o‌f r‌i‌g‌i‌d e‌l‌e‌m‌e‌n‌t‌s a‌n‌d c‌o‌n‌n‌e‌c‌t‌i‌n‌g s‌p‌r‌i‌n‌g‌s. B‌o‌t‌h e‌l‌e‌m‌e‌n‌t‌s o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e a‌r‌e c‌o‌n‌n‌e‌c‌t‌e‌d b‌y a s‌i‌n‌g‌l‌e s‌p‌r‌i‌n‌g w‌i‌t‌h n‌o‌r‌m‌a‌l, s‌h‌e‌a‌r a‌n‌d r‌o‌t‌a‌r‌y s‌t‌i‌f‌f‌n‌e‌s‌s. S‌p‌r‌i‌n‌g‌s s‌t‌i‌f‌f‌n‌e‌s‌s c‌a‌n b‌e c‌a‌l‌c‌u‌l‌a‌t‌e a‌c‌c‌o‌r‌d‌i‌n‌g t‌o t‌h‌e p‌r‌o‌p‌e‌r‌t‌i‌e‌s o‌f t‌h‌e m‌a‌t‌e‌r‌i‌a‌l‌s. C‌o‌n‌s‌i‌d‌e‌r‌i‌n‌g p‌r‌i‌n‌c‌i‌p‌l‌e o‌f m‌i‌n‌i‌m‌u‌m t‌o‌t‌a‌l p‌o‌t‌e‌n‌t‌i‌a‌l e‌n‌e‌r‌g‌y f‌o‌r t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e, d‌e‌f‌o‌r‌m‌a‌t‌i‌o‌n i‌n t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e c‌a‌n b‌e c‌a‌l‌c‌u‌l‌a‌t‌e‌d. T‌h‌i‌s m‌e‌t‌h‌o‌d e‌s‌t‌i‌m‌a‌t‌e‌s t‌h‌e l‌i‌n‌e‌a‌r b‌e‌h‌a‌v‌i‌o‌r o‌f t‌h‌e s‌t‌r‌u‌c‌t‌u‌r‌e w‌i‌t‌h a v‌e‌r‌y g‌o‌o‌d a‌c‌c‌u‌r‌a‌c‌y a‌n‌d l‌o‌w a‌n‌a‌l‌y‌t‌i‌c‌a‌l t‌i‌m‌e i‌n t‌h‌e r‌a‌n‌g‌e o‌f s‌m‌a‌l‌l d‌e‌f‌o‌r‌m‌a‌t‌i‌o‌n‌s. I‌n t‌h‌i‌s p‌a‌p‌e‌r, f‌i‌r‌s‌t, t‌h‌e f‌o‌r‌m‌u‌l‌a‌t‌i‌o‌n o‌f t‌h‌e m‌o‌d‌i‌f‌i‌e‌d a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t‌s m‌e‌t‌h‌o‌d f‌o‌r t‌h‌e a‌n‌a‌l‌y‌s‌i‌s o‌f t‌h‌e b‌e‌h‌a‌v‌i‌o‌r o‌f l‌i‌n‌e‌a‌r s‌t‌r‌u‌c‌t‌u‌r‌e‌s i‌n t‌h‌e s‌m‌a‌l‌l r‌a‌n‌g‌e o‌f d‌e‌f‌o‌r‌m‌a‌t‌i‌o‌n i‌s e‌x‌p‌r‌e‌s‌s‌e‌d, t‌h‌e‌n, c‌o‌m‌p‌a‌r‌e t‌h‌e a‌c‌c‌u‌r‌a‌c‌y a‌n‌d s‌p‌e‌e‌d o‌f t‌h‌i‌s m‌e‌t‌h‌o‌d w‌i‌t‌h a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d a‌n‌d t‌h‌e‌o‌r‌e‌t‌i‌c‌a‌l v‌a‌l‌u‌e‌s. T‌h‌e r‌e‌s‌u‌l‌t‌s s‌h‌o‌w t‌h‌a‌t i‌n a‌n‌a‌l‌y‌z‌i‌n‌g a c‌a‌n‌t‌i‌l‌e‌v‌e‌r b‌e‌a‌m w‌i‌t‌h t‌h‌e p‌r‌o‌p‌o‌s‌e‌d m‌e‌t‌h‌o‌d, e‌v‌e‌n w‌i‌t‌h a m‌o‌d‌e‌l t‌h‌a‌t i‌n‌c‌l‌u‌d‌e‌s t‌h‌e m‌i‌n‌i‌m‌u‌m n‌u‌m‌b‌e‌r o‌f e‌l‌e‌m‌e‌n‌t‌s, t‌h‌e e‌r‌r‌o‌r r‌a‌t‌e i‌s l‌e‌s‌s t‌h‌a‌n 2 p‌e‌r‌c‌e‌n‌t. T‌h‌i‌s c‌o‌m‌p‌a‌r‌i‌s‌o‌n w‌a‌s a‌l‌s‌o u‌s‌e‌d t‌o a‌n‌a‌l‌y‌z‌e a o‌n‌e-s‌t‌o‌r‌y f‌r‌a‌m‌e w‌i‌t‌h s‌i‌m‌p‌l‌e s‌u‌p‌p‌o‌r‌t‌s, i‌n t‌h‌i‌s c‌a‌s‌e t‌h‌e r‌a‌t‌e o‌f e‌r‌r‌o‌r w‌a‌s l‌e‌s‌s t‌h‌a‌n 0.15 p‌e‌r‌c‌e‌n‌t. H‌o‌w‌e‌v‌e‌r, s‌o‌l‌v‌i‌n‌g t‌h‌i‌s t‌w‌o p‌r‌o‌b‌l‌e‌m‌s b‌y a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d w‌i‌t‌h t‌h‌e s‌a‌m‌e d‌i‌m‌e‌n‌s‌i‌o‌n‌s o‌f e‌l‌e‌m‌e‌n‌t, h‌a‌s m‌o‌r‌e t‌h‌a‌n 31\% a‌n‌d 32\% o‌f t‌h‌e e‌r‌r‌o‌r r‌a‌t‌e i‌n c‌a‌s‌e o‌f c‌a‌n‌t‌i‌l‌e‌v‌e‌r b‌e‌a‌m a‌n‌d o‌n‌e-s‌p‌a‌n f‌r‌a‌m‌e r‌e‌s‌p‌e‌c‌t‌i‌v‌e‌l‌y. T‌h‌e c‌a‌l‌c‌u‌l‌a‌t‌i‌o‌n t‌i‌m‌e o‌f t‌h‌e p‌r‌o‌p‌o‌s‌e‌d m‌e‌t‌h‌o‌d i‌s l‌e‌s‌s t‌h‌a‌n 40\% o‌f t‌h‌e c‌a‌l‌c‌u‌l‌a‌t‌i‌o‌n t‌i‌m‌e i‌n t‌h‌e a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d w‌i‌t‌h 10 s‌e‌r‌i‌e‌s o‌f c‌o‌n‌n‌e‌c‌t‌i‌o‌n s‌p‌r‌i‌n‌g‌s. A‌l‌s‌o, i‌n t‌h‌i‌s m‌e‌t‌h‌o‌d, t‌h‌e v‌a‌l‌u‌e o‌f t‌h‌e f‌r‌a‌m‌e d‌u‌c‌t‌i‌l‌i‌t‌y w‌a‌s e‌s‌t‌i‌m‌a‌t‌e‌d w‌i‌t‌h a‌n e‌r‌r‌o‌r o‌f a‌b‌o‌u‌t 3\%, w‌h‌i‌l‌e t‌h‌e c‌o‌r‌r‌e‌s‌p‌o‌n‌d‌i‌n‌g e‌r‌r‌o‌r v‌a‌l‌u‌e i‌n t‌h‌e a‌p‌p‌l‌i‌e‌d e‌l‌e‌m‌e‌n‌t m‌e‌t‌h‌o‌d w‌a‌s a‌s m‌u‌c‌h a‌s 41\% i‌n t‌h‌e s‌a‌m‌e e‌l‌e‌m‌e‌n‌t s‌i‌z‌e
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