Kritische Edition der Sahidischen Version des Johannesevangeliums: Text und Dokumentation

Sahidic is the most important dialect of the Coptic language. Criticial editions of the Sahidic translation of the New Testament are a desideratum since many years. A research project (P29315) funded by the Austrian Science Fund (FWF) made the critical edition of the Sahidic Version of the Gospel of John possible. 172 different, mostly fragmentary manuscripts have been used for this edition.Sahidisch ist der wichtigste Literaturdialekt des Koptischen. Seit langem gelten moderne kritische Editionen der sahidischen Übersetzung des Neuen Testaments als Desiderat der Forschung. Ein Forschungsprojekt (P29315) des Österreichischen Wissenschaftsfonds (FWF) ermöglichte eine kritische Edition des sahidischen Johannesevangeliums. Ihr liegen 172 verschiedene, zu großen Teilen fragmentarisch erhaltene, Handschriften zugrunde

Toward the development of a virtual spray test-rig using the Smoothed Particle Hydrodynamics method

In this work we present the numerical simulation of air-assisted liquid atomization at high pressure us- ing the Smoothed Particle Hydrodynamics (SPH) method. Different post-processing tools are applied to facilitate the comparison with experimental observations. This allows to quantitatively validate the nu- merical method against the experiment, in terms of (i) frequency of the Kelvin–Helmholtz instability that develops on the jet surface, and (ii) statistical distribution of the jet intact length. The qualitative com- parison also shows a good prediction of the jet global instability and of the fragmented liquid lumps, with regards to length and time scales. In addition, the post-processing tools also give access to the local parameters of the generated spray in the vicinity of the nozzle, which are not easily accessible in a real experiments. Using these tools, 1D profiles and 2D maps of the liquid phase properties such as the vol- ume fraction, the droplet concentration, the Sauter Mean Diameter (SMD) and the droplet sphericity are presented. Because of the Lagrangian nature of the SPH method, it is also possible to monitor the whole atomization cascade as a causal tree, from the primary instabilities to the spray characteristics. This tree contains various information such as the fragmentation spectrum and the breakup activity, which are of great interest for researchers and engineers. Hence, the capability of the Smoothed Particle Hydrody- namics (SPH) method for simulating air-assisted atomization at high ambient pressure is demonstrated as well as its applicability to realistic configurations. This is a first step towards the development of a complete virtual spray test-rig

Kritische Edition der Sahidischen Version des Johannesevangeliums: Text und Dokumentation

Sahidic is the most important dialect of the Coptic language. Criticial editions of the Sahidic translation of the New Testament are a desideratum since many years. A research project (P29315) funded by the Austrian Science Fund (FWF) made the critical edition of the Sahidic Version of the Gospel of John possible. 172 different, mostly fragmentary manuscripts have been used for this edition

Vectorial Control of Magnetization by Light

Coherent light-matter interactions have recently extended their applications to the ultrafast control of magnetization in solids. An important but unrealized technique is the manipulation of magnetization vector motion to make it follow an arbitrarily designed multi-dimensional trajectory. Furthermore, for its realization, the phase and amplitude of degenerate modes need to be steered independently. A promising method is to employ Raman-type nonlinear optical processes induced by femtosecond laser pulses, where magnetic oscillations are induced impulsively with a controlled initial phase and an azimuthal angle that follows well defined selection rules determined by the materials' symmetries. Here, we emphasize the fact that temporal variation of the polarization angle of the laser pulses enables us to distinguish between the two degenerate modes. A full manipulation of two-dimensional magnetic oscillations is demonstrated in antiferromagnetic NiO by employing a pair of polarization-twisted optical pulses. These results have lead to a new concept of vectorial control of magnetization by light

Oscillatory Shear Flow-Induced Alignment of Lamellar Melts of Hydrogen-Bonded Comb Copolymer Supramolecules

In this work we present the orientational behavior of comb copolymer-like supramolecules P4VP(PDP)1.0, obtained by hydrogen bonding between poly(4-vinylpyridine) and pentadecylphenol, during large-amplitude oscillatory shear flow experiments over a broad range of frequencies (0.001-10 Hz). The alignment diagram, presenting the macroscopic alignment in T/TODT vs ω/ωc, contains three regions of parallel alignment separated by a region of perpendicular alignment. For our material, the order-disorder temperature TODT = 67 °C and ωc, the frequency above which the distortion of the chain conformation dominates the materials’ viscoelasticity, is around 0.1 Hz at 61 °C. For the first time flipping from a pure transverse alignment via biaxial transverse/perpendicular alignment to a perpendicular alignment as a function of the strain amplitude was found.

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

High attrition rates of novel anti-cancer drugs highlight the need for improved models to predict toxicity. Although polo-like kinase 1 (Plk1) inhibitors are attractive candidates for drug development, the role of Plk1 in primary cells remains widely unexplored. Therefore, we evaluated the utility of an RNA interference-based model to assess responses to an inducible knockdown (iKD) of Plk1 in adult mice. Here we show that Plk1 silencing can be achieved in several organs, although adverse events are rare. We compared responses in Plk1-iKD mice with those in primary cells kept under controlled culture conditions. In contrast to the addiction of many cancer cell lines to the non-oncogene Plk1, the primary cells' proliferation, spindle assembly and apoptosis exhibit only a low dependency on Plk1. Responses to Plk1-depletion, both in cultured primary cells and in our iKD-mouse model, correspond well and thus provide the basis for using validated iKD mice in predicting responses to therapeutic interventions

Sicherung von Dämmen, Deichen und Stauanlagen : Handbuch für Theorie und Praxis ; Vol. V - 2015

Die Universität Siegen beschäftigt sich seit über 15 Jahren wissenschaftlich und im Bereich der anwendungsorientierten Forschung mit diesem Thema und hat dazu mittlerweile fünf Symposien durchgeführt. Mit der Veröffentlichung soll die langjährige Tradition als etablierte wissenschaftliche Plattform mit einem Wissensaustausch auf europäischer Ebene fortgesetzt werden. Die Bearbeitung dieser Thematik erfolgt auf der Basis der bewährten Kooperation zwischen Geotechnik und Wasserbau an der Universität Siegen. Aktuelle Ereignisse, wie z.B. die aus England oder Australien im Februar des Jahres 2014, machen uns aber auch deutlich, dass ein absoluter Schutz gegen Extremereignisse nicht möglich ist. Sie zeigen aber auch, dass dort wo technischer Hochwasserschutz konsequent umgesetzt wurde Schäden vermieden werden konnten. Wir sind nach den Ereignissen in den vergangenen Jahren aufgefordert wissenschaftlich noch leistungsfähigere und duktilere Systeme zu entwickeln. Weiter ist die Wissenschaft in der Pflicht, die Zivile Sicherheit im Hochwasser-schutz permanent zu bewerten, zu bearbeiten und ganzheitliche-interdisziplinäre und länderübergreifende Lösungen für die Zivilgesellschaft einzufordern