An analysis of astronaut performance capability in the lunar environment. Volume 1 - Performance problems and requirements for additional research

Analyzing data on expected astronaut performance in lunar environmen

An Analysis of Astronaut Performance Capability in the Lunar Environment. Volume 2 - Performance Capability Support Data

Astronaut performance capability in lunar environmen

Direct Freeform Fabrication of Spatially Heterogeneous Living Cell-Impregnated Implants

The objectives of this work are the development of the processes, materials, and tooling to directly “3-D print” living, pre-seeded, patient-specific implants of spatially heterogeneous compositions. The research presented herein attempts to overcome some of the challenges to scaffolding, such as the difficulty of producing spatially heterogeneous implants that require varied seeding densities and/or cell-type distributions. In the proposed approach, living implants are fabricated by the layer-wise deposition of pre-cell-seeded alginate hydrogel. Although alginate hydrogels have been previously used to mold living implants, the properties of the alginate formulations used for molding were not suitable for 3-D printing. In addition to changing the formulation to make the alginate hydrogels “printable,” we developed a robotic hydrogel deposition system and supporting CAD software to deposit the gel in arbitrary geometries. We demonstrated this technology’s capabilities by printing alginate gel implants of multiple materials with various spatial heterogeneities, including, implants with completely embedded material clusters. The process was determined to be both viable (94±5% n=15) and sterile (less than one bacterium per 0.9 µL after 8 days of incubation). Additionally, we demonstrated the printing of a meniscus cartilage-shaped gel generated directly from a CT Scan. The proposed approach may hold advantages over other tissue printing efforts [5,9]. This technology has the potential to overcome challenges to scaffolding and could enable the efficient fabrication of spatially heterogeneous, patient-specific, living implants.Mechanical Engineerin

Holy Bass: Spirituality in Electronic Dance Music Culture

Throughout human history, religious systems have provided individuals with basic knowledge and guidance used to understand and navigate the world. The modern world is no different with people searching for the sacred in new ways and different places. This thesis examines Electronic Dance Music Culture as an example. In order to study spirituality in EDMC I conducted an ethnography of EDM artists. In doing so I set out to answer these questions: How do the facilitators of EDMC conceptualize spirituality and how do those processes interact within EDMCs? So the focus does not lie in discerning a unifying spirituality of EDMC but in teasing out the impact of EDM and EDMC on individuals in the personal construction of their spiritual selves. I draw upon ethnographic research to explain how the creators of EDMC conceptualize and construct spirituality in open-ended ways. I found that the DJs and producers have a dual relationship with the scene as specialist and member both creating, facilitating and engaging

Consideration of radar target glint from ST during OMV rendezvous

The nature of radar target glint and the factors upon which it depends when using the Hubble Space Telescope as a radar target is discussed. An analysis of the glint problem using a 35 MHz or 94 MHz radar on the orbital maneuvering vehicle is explored. A strategy for overcoming glint is suggested

Unmixing Detrital Zircon U-Pb Ages Reveals Tectonic and Climatic Depositional Influences on the Carboniferous Ansilta Formation, Calingasta-Uspallata Basin, Western Argentina

The Late Paleozoic Ice Age (LPIA) was a principal control of sedimentation across Gondwana from the late Devonian through early Permian. We assess the hypothesis that glacial to interglacial transitions in western Argentina were the primary control influencing sediment routing patterns among the various Carboniferous-Permian basins in western Argentina. The Carboniferous Ansilta Formation consists of glaciomarine, nearshore, and fluvial systems deposited during the LPIA along the eastern margin of the Calingasta-Uspallata Basin in Argentina. The lower, glacially influenced succession of the Ansilta Formation records at least five glacial advances; the upper succession of consists of progradational shallow marine, deltaic, and fluvial strata. We combine 1225 new U–Pb zircon ages from six samples of the Carboniferous Ansilta Formation in the Calingasta-Uspallata Basin with 5864 U–Pb ages from 147 published samples in the detritalPy-mix forward mixture model to characterize provenance shifts. For the glacially influenced lower Ansilta Formation, sediment was derived locally from the Protoprecordillera, which was a prominent highland with alpine glaciers flowing west and east into the CalingastaUspallata and Paganzo basins, respectively. Thus, there was little or no connection between these two basins during Serpukhovian-Bashkirian glaciation. The fluvial/deltaic upper Ansilta had distal sediment sources in the Sierras Pampeanas. Furthermore, our results support the collapse of the Protoprecordillera topographic barrier, enabling drainage patterns connecting the Paganzo and Calingasta-Uspallata basins by late Pennsylvanian-early Permian time

A realistic evaluation : the case of protocol-based care

Background 'Protocol based care' was envisioned by policy makers as a mechanism for delivering on the service improvement agenda in England. Realistic evaluation is an increasingly popular approach, but few published examples exist, particularly in implementation research. To fill this gap, within this paper we describe the application of a realistic evaluation approach to the study of protocol-based care, whilst sharing findings of relevance about standardising care through the use of protocols, guidelines, and pathways. Methods Situated between positivism and relativism, realistic evaluation is concerned with the identification of underlying causal mechanisms, how they work, and under what conditions. Fundamentally it focuses attention on finding out what works, for whom, how, and in what circumstances. Results In this research, we were interested in understanding the relationships between the type and nature of particular approaches to protocol-based care (mechanisms), within different clinical settings (context), and what impacts this resulted in (outcomes). An evidence review using the principles of realist synthesis resulted in a number of propositions, i.e., context, mechanism, and outcome threads (CMOs). These propositions were then 'tested' through multiple case studies, using multiple methods including non-participant observation, interviews, and document analysis through an iterative analysis process. The initial propositions (conjectured CMOs) only partially corresponded to the findings that emerged during analysis. From the iterative analysis process of scrutinising mechanisms, context, and outcomes we were able to draw out some theoretically generalisable features about what works, for whom, how, and what circumstances in relation to the use of standardised care approaches (refined CMOs). Conclusions As one of the first studies to apply realistic evaluation in implementation research, it was a good fit, particularly given the growing emphasis on understanding how context influences evidence-based practice. The strengths and limitations of the approach are considered, including how to operationalise it and some of the challenges. This approach provided a useful interpretive framework with which to make sense of the multiple factors that were simultaneously at play and being observed through various data sources, and for developing explanatory theory about using standardised care approaches in practice