986 research outputs found
An analysis of gentrification’s effects on LGBTQ+ populations in Louisville, Kentucky.
This study attempts to examine and the analyze the process of gentrification amongst identified LGBTQ+ spaces in Louisville, Kentucky from 1980 to present day using both production-side and consumption-side methods derived from property values and census data, respectively. Using these data, I trace the development of these spaces and determine what relationship to gentrification they may have. I then compare production-side data with consumption-side data to determine disparities amongst class in potential LGBTQ+ bar patrons in Louisville, Kentucky
Synthesis, biological evaluation and mode of action studies of novel amidinourea inhibitors of Hepatitis C Virus
Novel amidinourea derivatives have been synthesised and evaluated for their antiviral activity against Hepatitis C Virus (HCV). A compound with an amidinourea-spermine chemical structure, different from that of standard anti-HCV drugs, showed micromolar activity against HCV and excellent viability. Studies on the mode of action revealed that the new compound may act against HCV through the inhibition of IRES-mediated translation
Sclerosing Haemangiomas of the Liver: Two Cases of Mistaken Identity
We describe two cases where patients undergoing hepatic resection for metastatic disease of colorectal origin were found to have concomitant sclerosing haemangiomas. The typical radiological and histological appearances of these lesions are discussed
How to determine linear complexity and -error linear complexity in some classes of linear recurring sequences
Several fast algorithms for the determination of the linear complexity of -periodic sequences over a finite
field \F_q, i.e. sequences with characteristic polynomial , have been proposed in the literature.
In this contribution fast algorithms for determining the linear complexity of binary sequences with characteristic
polynomial for an arbitrary positive integer , and are presented.
The result is then utilized to establish a fast algorithm for determining the -error linear complexity of
binary sequences with characteristic polynomial
Kaleidoscope laser
We report the first calculations of mode patterns of unstable-cavity lasers with truly two-dimensional transverse geometries. A detailed account of numerical techniques, incorporating a nonorthogonal beam-propagation method, and results for cavities with a range of transverse symmetries, such as regular polygonal and rhomboid, are presented. In view of the beautiful complexity of the eigenmodes predicted, a novel kaleidoscope laser is proposed
On the rules for aquatic locomotion
We present unifying rules governing the efficient locomotion of swimming fish and marine mammals. Using scaling and dimensional analysis, supported by new experimental data, we show that efficient locomotion occurs when the values of the Strouhal (St) number St(=f A/U) and A∗(=A/L), two nondimensional numbers that relate forward speed U, tail-beat amplitude A, tail-beat frequency f , and the length of the swimmer L are bound to the tight ranges of 0.2–0.4 and 0.1–0.3, respectively. The tight range of 0.2–0.4 for the St number has previously been associated with optimal thrust generation. We show that the St number alone is insufficient to achieve optimal aquatic locomotion, and an additional condition on A∗ is needed. More importantly, we show that when swimming at minimal power consumption, the Strouhal number of a cruising swimmer is predetermined solely by the shape and drag characteristics of the swimmer. We show that diverse species of fish and cetaceans cruise indeed with the St number and A∗ predicted by our theory. Our findings provide a physical explanation as to why fast aquatic swimmers cruise with a relatively constant tail-beat amplitude of approximately 20% of the body length, and their swimming speed is nearly proportional to their tail-beat frequenc
Effects of non-uniform stiffness on the swimming performance of a passively-flexing, fish-like foil model
Author Posting. © The Author(s), 2015. This is the author's version of the work. It is posted here by permission of IOP Science for personal use, not for redistribution. The definitive version was published in Bioinspiration & Biomimetics 10 (2015): 056019, doi:10.1088/1748-3190/10/5/056019.Simple mechanical models emulating fish have been used recently to enable targeted study of individual factors contributing to swimming locomotion without the confounding complexity of the whole fish body. Yet, unlike these uniform models, the fish body is notable for its non-uniform material properties. In particular, flexural stiffness decreases along the fish’s anterior-posterior axis. To identify the role of non-uniform bending stiffness during fish-like propulsion, we studied four foil model configurations made by adhering layers of plastic sheets to produce discrete regions of high (5.5x10-5 Nm2) and low (1.9x10-5 Nm2) flexural stiffness of biologically-relevant magnitudes. This resulted in two uniform control foils and two foils with anterior regions of high stiffness and posterior regions of low stiffness. With a mechanical flapping foil controller, we measured forces and torques in three directions and quantified swimming performance under both heaving (no pitch) and constant 0o angle of attack programs. Foils self-propelled at Reynolds number 21,000-115,000 and Strouhal number ~0.20-0.25, values characteristic of fish locomotion. Although previous models have emphasized uniform distributions and heaving motions, the combination of non-uniform stiffness distributions and 0o angle of attack pitching program was better able to reproduce the kinematics of freely-swimming fish. This combination was likewise crucial in maximizing swimming performance and resulted in high self-propelled speeds at low costs of transport and large thrust coefficients at relatively high efficiency. Because these metrics were not all maximized together, selection of the “best” stiffness distribution will depend on actuation constraints and performance goals. These improved models enable more detailed, accurate analyses of fish-like swimming.This work was supported by an NSF Graduate Research Fellowship under grant DGE-1144152 to KNL and by ONR MURI Grant N000141410533 monitored by Dr Bob Brizzolara to GVL.2016-10-0
The impact of marketisation on postgraduate career preparedness in a high skills economy
This study focuses on the consequences for high skills development of the erosion of the once clear demarcation between higher education and business. It contributes to the broader debate about the relevance of higher education for thewell-being of the society of the future. The research explores the effects of marketisation on the postgraduate curriculum and students’ preparedness for careers in public relations and marketing communications. Interviews with lecturers and students in two universities in the UK and Australia indicate that a tension exists between academic rigour and corporate relevancy. The consequences are a diminution of academic attachment to critique and wider social/cultural engagement, with a resulting impoverishment of students’ creative abilities and critical consciences. Subsequently, graduates of public relations and marketing communications, and to some extent those from other profession-related disciplines, are insufficiently prepared for careers as knowledge workers in a future high-skills economy
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