6,692 research outputs found

    On-Line Optimizing Control of a Simulated Continuous Yeast Fermentation

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    Towards learning free naive bayes nearest neighbor-based domain adaptation

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    As of today, object categorization algorithms are not able to achieve the level of robustness and generality necessary to work reliably in the real world. Even the most powerful convolutional neural network we can train fails to perform satisfactorily when trained and tested on data from different databases. This issue, known as domain adaptation and/or dataset bias in the literature, is due to a distribution mismatch between data collections. Methods addressing it go from max-margin classifiers to learning how to modify the features and obtain a more robust representation. Recent work showed that by casting the problem into the image-to-class recognition framework, the domain adaptation problem is significantly alleviated [23]. Here we follow this approach, and show how a very simple, learning free Naive Bayes Nearest Neighbor (NBNN)-based domain adaptation algorithm can significantly alleviate the distribution mismatch among source and target data, especially when the number of classes and the number of sources grow. Experiments on standard benchmarks used in the literature show that our approach (a) is competitive with the current state of the art on small scale problems, and (b) achieves the current state of the art as the number of classes and sources grows, with minimal computational requirements. © Springer International Publishing Switzerland 2015

    Target Mass Monitoring and Instrumentation in the Daya Bay Antineutrino Detectors

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    The Daya Bay experiment measures sin^2 2{\theta}_13 using functionally identical antineutrino detectors located at distances of 300 to 2000 meters from the Daya Bay nuclear power complex. Each detector consists of three nested fluid volumes surrounded by photomultiplier tubes. These volumes are coupled to overflow tanks on top of the detector to allow for thermal expansion of the liquid. Antineutrinos are detected through the inverse beta decay reaction on the proton-rich scintillator target. A precise and continuous measurement of the detector's central target mass is achieved by monitoring the the fluid level in the overflow tanks with cameras and ultrasonic and capacitive sensors. In addition, the monitoring system records detector temperature and levelness at multiple positions. This monitoring information allows the precise determination of the detectors' effective number of target protons during data taking. We present the design, calibration, installation and in-situ tests of the Daya Bay real-time antineutrino detector monitoring sensors and readout electronics.Comment: 22 pages, 20 figures; accepted by JINST. Changes in v2: minor revisions to incorporate editorial feedback from JINS

    Heat shock proteins and neurodegenerative disorders

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    10.1100/tsw.2008.48TheScientificWorldJournal8270-27

    Nanopatterning of epitaxial CoSi₂ using oxidation in a local stress field and fabrication of nanometer metal-oxide-semiconductor field-effect transistors

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    A patterning method for the generation of epitaxialCoSi₂nanostructures was developed based on anisotropic diffusion of Co∕Si atoms in a stress field during rapid thermal oxidation (RTO). The stress field is generated along the edge of a mask consisting of a thin SiO₂ layer and a Si₃N₄ layer. During RTO of the masked silicide structure, a well-defined separation of the silicide layer forms along the edge of the mask. The technique was used to make 50-nm channel-length metal-oxide-semiconductor field-effect transistors(MOSFETs). These highly uniform gaps define the channel region of the fabricated device. Two types of MOSFETs have been fabricated: symmetric transistor structures, using the separated silicide layers as Schottky source and drain, and asymmetric transistors, with n+ source and Schottky drain. The asymmetric transistors were fabricated by an ion implantation into the unprotected CoSi₂ layer and a subsequent out diffusion to form the n+ source. The detailed fabrication process as well as the I–V characteristics of both the symmetric and asymmetric transistor structures will be presented

    Accurate and linear time pose estimation from points and lines

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    The final publication is available at link.springer.comThe Perspective-n-Point (PnP) problem seeks to estimate the pose of a calibrated camera from n 3Dto-2D point correspondences. There are situations, though, where PnP solutions are prone to fail because feature point correspondences cannot be reliably estimated (e.g. scenes with repetitive patterns or with low texture). In such scenarios, one can still exploit alternative geometric entities, such as lines, yielding the so-called Perspective-n-Line (PnL) algorithms. Unfortunately, existing PnL solutions are not as accurate and efficient as their point-based counterparts. In this paper we propose a novel approach to introduce 3D-to-2D line correspondences into a PnP formulation, allowing to simultaneously process points and lines. For this purpose we introduce an algebraic line error that can be formulated as linear constraints on the line endpoints, even when these are not directly observable. These constraints can then be naturally integrated within the linear formulations of two state-of-the-art point-based algorithms, the OPnP and the EPnP, allowing them to indistinctly handle points, lines, or a combination of them. Exhaustive experiments show that the proposed formulation brings remarkable boost in performance compared to only point or only line based solutions, with a negligible computational overhead compared to the original OPnP and EPnP.Peer ReviewedPostprint (author's final draft

    Metallothionein 1E mRNA is highly expressed in oestrogen receptor-negative human invasive ductal breast cancer

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    Metallothioneins (MTs), a group of ubiquitous metalloproteins, comprise isoforms encoded by ten functional genes in humans. Different MT isoforms possibly play different functional roles during development or under various physiological conditions. The MT-1E isoform mRNA has been recently shown to be differentially expressed in oestrogen receptor (OR)-positive and OR-negative breast cancer cell lines. In this study, we evaluated MT-1E mRNA expression via semi-quantitative RT-PCR in 51 primary invasive ductal breast cancer tissues, concurrently with OR-positive and progesterone receptor (PR)-positive MCF7 cells, OR-negative and PR-negative MDA-MB-231 cells and PR-transfected MDA-MB-231 breast cancer cells (ABC28). We demonstrated significantly higher MT-1E mRNA expression in OR-negative compared with OR-positive breast cancer tissues (P= 0.026). MCF7 cells lacked MT-1E mRNA expression, while both OR- and PR-negative MDA-MD-231 cells exhibited a high level of MT-1E mRNA expression. The level of MT-1E mRNA expression in progesterone-treated and -untreated ABC28 cells remained similar as the parental cell line MDA-MB-231-C2 cells. The results suggest that MT-1E may have specific and functional roles in OR-negative invasive ductal breast cancers, possibly mediated via effector genes downstream of the oestrogen receptor, but not through the PR pathway. © 2000 Cancer Research Campaig

    A fast neural-dynamical approach to scale-invariant object detection

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    We present a biologically-inspired method for object detection which is capable of online and one-shot learning of object appearance. We use a computationally efficient model of V1 keypoints to select object parts with the highest information content and model their surroundings by a simple binary descriptor based on responses of cortical cells. We feed these features into a dynamical neural network which binds compatible features together by employing a Bayesian criterion and a set of previously observed object views. We demonstrate the feasibility of our algorithm for cognitive robotic scenarios by evaluating detection performance on a dataset of common household items. © Springer International Publishing Switzerland 2014

    Purposive sample consensus: A paradigm for model fitting with application to visual odometry

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    © Springer International Publishing Switzerland 2015. ANSAC (random sample consensus) is a robust algorithm for model fitting and outliers' removal, however, it is neither efficient nor reliable enough to meet the requirement of many applications where time and precision is critical. Various algorithms have been developed to improve its performance for model fitting. A new algorithm named PURSAC (purposive sample consensus) is introduced in this paper, which has three major steps to address the limitations of RANSAC and its variants. Firstly, instead of assuming all the samples have a same probability to be inliers, PURSAC seeks their differences and purposively selects sample sets. Secondly, as sampling noise always exists; the selection is also according to the sensitivity analysis of a model against the noise. The final step is to apply a local optimization for further improving its model fitting performance. Tests show that PURSAC can achieve very high model fitting certainty with a small number of iterations. Two cases are investigated for PURSAC implementation. It is applied to line fitting to explain its principles, and then to feature based visual odometry, which requires efficient, robust and precise model fitting. Experimental results demonstrate that PURSAC improves the accuracy and efficiency of fundamental matrix estimation dramatically, resulting in a precise and fast visual odometry
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