On the absolute Nörlund summability factors

In this paper a theorem on the absolute Nörlund summability factors has been proved under more weaker conditions by using an almost increasing sequence

A new application of generalized quasipower increasing sequences

We prove a theorem on ∣ N¯,pn,θn ∣k-summability by using a new general class of power increasing sequences instead of a quasi-η-power increasing sequence. This theorem also includes some new and known results.Доведено теорему про | N¯, pn, θn |k-сумовнiсть iз використанням нового загального класу послiдовностей степеневого зростання замiсть послiдовностi квазi-η-степеневого зростання. Окремими випадками цiєї теореми є деякi новi та вiдомi результати

Limiting shapes of confined lipid vesicles

We theoretically study the shapes of lipid vesicles confined to a spherical cavity, elaborating a framework based on the so-called limiting shapes constructed from geometrically simple structural elements such as double-membrane walls and edges. Partly inspired by numerical results, the proposed non-compartmentalized and compartmentalized limiting shapes are arranged in the bilayer-couple phase diagram which is then compared to its free-vesicle counterpart. We also compute the area-difference-elasticity phase diagram of the limiting shapes and we use it to interpret shape transitions experimentally observed in vesicles confined within another vesicle. The limiting-shape framework may be generalized to theoretically investigate the structure of certain cell organelles such as the mitochondrion

Understanding success and failure in innovative Australian resource processing projects

This thesis in concerned with the understanding of success and failure of innovation in resource processing, a sector that is central to the Australian economy. Decline in ore grade, complexity of available ore resources, increases in labour and capital cost, and increased market demand have driven innovation and larger resource processing projects. The outcomes from innovation investment have been disappointing, and not well understood. This thesis aims to understand why so many large resource processing projects fail, and what factors have been critical in other projects that succeed. It proposes a new model for innovation investment, based on public domain data and an outsider view. Five criteria are used in this thesis to classify success and failure of large resource processing projects; that (1) the project and firm made a profit, in failure the project made a loss, (2) the production in the first 36 months of operation is 90% or more of nameplate capacity, while a failure is less than 70%, (3) return on investment is below 105 months, failure above 105 months, average for successful projects is found to be 53 months,. (4) failure sees project and or firm fail, with the plant selling for less than 20% of cost, success sees the project continue to produce at close to capacity, and if sold was value at close to investment, and (5) the successful process is reproduced; in the case of failure it is not. The thesis examines a sample of 67 resource processing projects in Australia initially valued at over $100 million each, over an 18 year interval between 1993 and 2010. The projects totalled$45.3 billion in value with 73% of classified as successful, while 15 projects failed. Four hypotheses are proposed and tested, each respectively relating to one of the following four factors; (1) Firm competence, (2) new process innovation, (3) government involvement in value adding, and (4) information asymmetry and strategic misrepresentation

Single-Payer National Health Insurance: Physicians\u27 Views

Background Forty-one million Americans have no health insurance and, despite the growth of managed care, medical costs are again increasing rapidly. One proposed solution is a single-payer health care financing system with universal coverage. Yet, physicians\u27 views of such a system have not been well studied. Methods We surveyed a random sample of physicians (from the American Medical Association Masterfile) in Massachusetts, regarding their views on a single-payer health care financing system and other financing and physician work-life issues that such a system might affect. Results Of 1787 physicians, 904 (50.6%) responded to our survey. When asked which structure would provide the best care for the most people for a fixed amount of money, 63.5% of physicians chose a single-payer system; 10. 7%, managed care; and 25.8%, a fee-for-service system. Only 51.9% believed that most physician colleagues would support a single-payer system. Most respondents would give up income to reduce paperwork, agree that it is government\u27s responsibility to ensure the provision of medical care, believe that insurance firms should not play a major role in health care delivery, and would prefer to work under a salary system. Conclusions Most physicians in Massachusetts, a state with a high managed care penetration, believe that single-payer financing of health care with universal coverage would provide the best care for the most people, compared with a managed care or fee-for-service system. Physicians\u27 advocacy of single-payer national health insurance could catalyze a renewed push for its adoption

Impurity band induced by point defects in graphene

It is pointed out that point defects on graphene are strongly correlated and can not be treated as independent scatters. In particular, for large on-site defect potential, it is shown that defects induce an impurity band with density of state characterized by the Wigner semi-circle law. We find that the impurity band enhances conductivity to the order of $4 e^2 /h$ and explains the absence of strong localization. Furthermore,the impurity band supports ferromagnetism with the induced magnetic moment approaching 1$\mu_B$ per defect in the limit of infinite quasi-particle lifetime.Comment: 4, pages, 2 figure

Maternal Anxiety and Depression, Poverty and Marital Relationship Factors During Early Childhood as Predictors of Anxiety and Depressive Symptoms in Adolescence

BACKGROUND This paper examines the degree to which symptoms of anxiety and depression at age 14 years are associated with early childhood experience of maternal anxiety and depression, poverty, and mother's marital relationship distress and break-up. METHODS In a longitudinal study, 4434 families were followed-up from infancy to adolescence. RESULTS: Maternal anxiety and depression during early childhood were found to have small, but significant, influences upon the development of high anxiety-depression symptoms at age 14, after controlling for the effects of poverty and marital relationship factors. This effect was greater with repeated exposure to high maternal anxiety and depression. Poverty, distressed marital relationship and marital break-up during the child's first five years also produced small, but significant, increases in risk of high anxiety and depression symptoms in adolescence. Stable, single-parent status was not found to be a risk factor. There was no evidence of marked gender differences in risk factors, other than poverty, which had a stronger impact for girls than boys. CONCLUSIONS Overall, the results suggest that maternal anxiety and depression, poverty, parent relationship conflict and marital break-up during early childhood are associated with small, but significant, increased risk of anxiety-depression symptoms in adolescence

Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa?

This version is the Accepted Manuscript and is published in final edited form as: AIDS. 2017 January 02; 31(1): 147–157. doi:10.1097/QAD.0000000000001307OBJECTIVE: We assessed the relationship between phasing out stavudine in first-line antiretroviral therapy (ART) in accordance with WHO 2010 policy and single-drug substitutions (SDS) (substituting the nucleoside reverse transcriptase inhibitor in first-line ART) in sub-Saharan Africa. DESIGN: Prospective cohort analysis (International epidemiological Databases to Evaluate AIDS-Multiregional) including ART-naive, HIV-infected patients aged at least 16 years, initiating ART between January 2005 and December 2012. Before April 2010 (July 2007 in Zambia) national guidelines called for patients to initiate stavudine-based or zidovudine-based regimen, whereas thereafter tenofovir or zidovudine replaced stavudine in first-line ART. METHODS: We evaluated the frequency of stavudine use and SDS by calendar year 2004-2014. Competing risk regression was used to assess the association between nucleoside reverse transcriptase inhibitor use and SDS in the first 24 months on ART. RESULTS: In all, 33 441 (8.9%; 95% confience interval 8.7-8.9%) SDS occurred among 377 656 patients in the first 24 months on ART, close to 40% of which were amongst patients on stavudine. The decrease in SDS corresponded with the phasing out of stavudine. Competing risks regression models showed that patients on tenofovir were 20-95% less likely to require a SDS than patients on stavudine, whereas patients on zidovudine had a 75-85% decrease in the hazards of SDS when compared to stavudine. CONCLUSION: The decline in SDS in the first 24 months on treatment appears to be associated with phasing out stavudine for zidovudine or tenofovir in first-line ART in our study. Further efforts to decrease the cost of tenofovir and zidovudine for use in this setting is warranted to substitute all patients still receiving stavudine