The Collective Dynamics of Smoking in a Large Social Network

Based on repeated surveys of 12,067 closely interconnected people between 1971 and 2000, examines the extent to which smoking spreads socially and to which groups of smokers quit together, as well as trends in the number and social centrality of smokers

Friendship and Natural Selection

More than any other species, humans form social ties to individuals who are neither kin nor mates, and these ties tend to be with similar people. Here, we show that this similarity extends to genotypes. Across the whole genome, friends' genotypes at the SNP level tend to be positively correlated (homophilic); however, certain genotypes are negatively correlated (heterophilic). A focused gene set analysis suggests that some of the overall correlation can be explained by specific systems; for example, an olfactory gene set is homophilic and an immune system gene set is heterophilic. Finally, homophilic genotypes exhibit significantly higher measures of positive selection, suggesting that, on average, they may yield a synergistic fitness advantage that has been helping to drive recent human evolution

Refactoring Legacy JavaScript Code to Use Classes: The Good, The Bad and The Ugly

JavaScript systems are becoming increasingly complex and large. To tackle the challenges involved in implementing these systems, the language is evolving to include several constructions for programming- in-the-large. For example, although the language is prototype-based, the latest JavaScript standard, named ECMAScript 6 (ES6), provides native support for implementing classes. Even though most modern web browsers support ES6, only a very few applications use the class syntax. In this paper, we analyze the process of migrating structures that emulate classes in legacy JavaScript code to adopt the new syntax for classes introduced by ES6. We apply a set of migration rules on eight legacy JavaScript systems. In our study, we document: (a) cases that are straightforward to migrate (the good parts); (b) cases that require manual and ad-hoc migration (the bad parts); and (c) cases that cannot be migrated due to limitations and restrictions of ES6 (the ugly parts). Six out of eight systems (75%) contain instances of bad and/or ugly cases. We also collect the perceptions of JavaScript developers about migrating their code to use the new syntax for classes.Comment: Paper accepted at 16th International Conference on Software Reuse (ICSR), 2017; 16 page

Fluctuations in the level density of a Fermi gas

We present a theory that accurately describes the counting of excited states of a noninteracting fermionic gas. At high excitation energies the results reproduce Bethe's theory. At low energies oscillatory corrections to the many--body density of states, related to shell effects, are obtained. The fluctuations depend non-trivially on energy and particle number. Universality and connections with Poisson statistics and random matrix theory are established for regular and chaotic single--particle motion.Comment: 4 pages, 1 figur

Engaging the articulators enhances perception of concordant visible speech movements

PURPOSE This study aimed to test whether (and how) somatosensory feedback signals from the vocal tract affect concurrent unimodal visual speech perception. METHOD Participants discriminated pairs of silent visual utterances of vowels under 3 experimental conditions: (a) normal (baseline) and while holding either (b) a bite block or (c) a lip tube in their mouths. To test the specificity of somatosensory-visual interactions during perception, we assessed discrimination of vowel contrasts optically distinguished based on their mandibular (English /ɛ/-/æ/) or labial (English /u/-French /u/) postures. In addition, we assessed perception of each contrast using dynamically articulating videos and static (single-frame) images of each gesture (at vowel midpoint). RESULTS Engaging the jaw selectively facilitated perception of the dynamic gestures optically distinct in terms of jaw height, whereas engaging the lips selectively facilitated perception of the dynamic gestures optically distinct in terms of their degree of lip compression and protrusion. Thus, participants perceived visible speech movements in relation to the configuration and shape of their own vocal tract (and possibly their ability to produce covert vowel production-like movements). In contrast, engaging the articulators had no effect when the speaking faces did not move, suggesting that the somatosensory inputs affected perception of time-varying kinematic information rather than changes in target (movement end point) mouth shapes. CONCLUSIONS These findings suggest that orofacial somatosensory inputs associated with speech production prime premotor and somatosensory brain regions involved in the sensorimotor control of speech, thereby facilitating perception of concordant visible speech movements. SUPPLEMENTAL MATERIAL https://doi.org/10.23641/asha.9911846R01 DC002852 - NIDCD NIH HHSAccepted manuscrip

The conceptus induces a switch in protein expression and activities of superoxide dismutase 1 and 2 in the sheep endometrium during early pregnancy

Acknowledgements We thank Philippe Bolifraud (INRA, France), Krawiec Angele, Sandra Grange, Laurence Puillet-Anselme (CHU Grenoble, France) and Margaret Fraser (Aberdeen, UK) for their expert technical assistance. The authors also thank the staff of the sheep sheds of Jouy-en-Josas (INRA, France). The authors would also like to thank the anonymous reviewers for their close examination of this article and their useful comments. Funding This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.Peer reviewedPostprin

The application of remote sensing to the development and formulation of hydrologic planning models

A hydrologic planning model is developed based on remotely sensed inputs. Data from LANDSAT 1 are used to supply the model's quantitative parameters and coefficients. The use of LANDSAT data as information input to all categories of hydrologic models requiring quantitative surface parameters for their effects functioning is also investigated