42,462 research outputs found
Consequences of the partial restoration of chiral symmetry in AdS/QCD
Chiral symmetry is an essential concept in understanding QCD at low energy.
We treat the chiral condensate, which measures the spontaneous breaking of
chiral symmetry, as a free parameter to investigate the effect of partially
restored chiral symmetry on the physical quantities in the frame work of an
AdS/QCD model. We observe an interesting scaling behavior among the nucleon
mass, pion decay constant and chiral condensate. We propose a phenomenological
way to introduce the temperature dependence of a physical quantity in the
AdS/QCD model with the thermal AdS metric.Comment: 11 pages, 6 figure
Anomalous diffusion in polymers: long-time behaviour
We study the Dirichlet boundary value problem for viscoelastic diffusion in
polymers. We show that its weak solutions generate a dissipative semiflow. We
construct the minimal trajectory attractor and the global attractor for this
problem.Comment: 13 page
The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.
Low-grade gliomas are one of the most common brain tumors in children, where they frequently form within the optic pathway (optic pathway gliomas; OPGs). Since many OPGs occur in the context of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome, we have previously employed Nf1 genetically-engineered mouse (GEM) strains to study the pathogenesis of these low-grade glial neoplasms. In the light of the finding that human and mouse low-grade gliomas are composed of Olig2+ cells and that Olig2+ oligodendrocyte precursor cells (OPCs) give rise to murine high-grade gliomas, we sought to determine whether Olig2+ OPCs could be tumor-initiating cells for Nf1 optic glioma. Similar to the GFAP-Cre transgenic strain previously employed to generate Nf1 optic gliomas, Olig2+ cells also give rise to astrocytes in the murine optic nerve in vivo. However, in contrast to the GFAP-Cre strain where somatic Nf1 inactivation in embryonic neural progenitor/stem cells (Nf1flox/mut; GFAP-Cre mice) results in optic gliomas by 3 months of age in vivo, mice with Nf1 gene inactivation in Olig2+ OPCs (Nf1flox/mut; Olig2-Cre mice) do not form optic gliomas until 6 months of age. These distinct patterns of glioma latency do not reflect differences in the timing or brain location of somatic Nf1 loss. Instead, they most likely reflect the cell of origin, as somatic Nf1 loss in CD133+ neural progenitor/stem cells during late embryogenesis results in optic gliomas at 3 months of age. Collectively, these data demonstrate that the cell of origin dictates the time to tumorigenesis in murine optic glioma
Divergence and Shannon information in genomes
Shannon information (SI) and its special case, divergence, are defined for a
DNA sequence in terms of probabilities of chemical words in the sequence and
are computed for a set of complete genomes highly diverse in length and
composition. We find the following: SI (but not divergence) is inversely
proportional to sequence length for a random sequence but is length-independent
for genomes; the genomic SI is always greater and, for shorter words and longer
sequences, hundreds to thousands times greater than the SI in a random sequence
whose length and composition match those of the genome; genomic SIs appear to
have word-length dependent universal values. The universality is inferred to be
an evolution footprint of a universal mode for genome growth.Comment: 4 pages, 3 tables, 2 figure
Symplectic geometry on moduli spaces of J-holomorphic curves
Let (M,\omega) be a symplectic manifold, and Sigma a compact Riemann surface.
We define a 2-form on the space of immersed symplectic surfaces in M, and show
that the form is closed and non-degenerate, up to reparametrizations. Then we
give conditions on a compatible almost complex structure J on (M,\omega) that
ensure that the restriction of the form to the moduli space of simple immersed
J-holomorphic Sigma-curves in a homology class A in H_2(M,\Z) is a symplectic
form, and show applications and examples. In particular, we deduce sufficient
conditions for the existence of J-holomorphic Sigma-curves in a given homology
class for a generic J.Comment: 16 page
Distinguishing sequences for partially specified FSMs
Distinguishing Sequences (DSs) are used inmany Finite State Machine (FSM) based test techniques. Although Partially Specified FSMs (PSFSMs) generalise FSMs, the computational complexity of constructing Adaptive and Preset DSs (ADSs/PDSs) for PSFSMs has not been addressed. This paper shows that it is possible to check the existence of an ADS in polynomial time but the corresponding problem for PDSs is PSPACE-complete. We also report on the results of experiments with benchmarks and over 8 * 106 PSFSMs. © 2014 Springer International Publishing
Health effects in fish of long-term exposure to effluents from wastewater treatment works
The effects of simple mixtures of chemicals, with similar mechanisms of action, can be predicted using the concentration addition model (CA). The ability of this model to predict the estrogenic effects of more complex mixtures such as effluent discharges, however, has yet to be established. Effluents from 43 U.K. wastewater treatment works were analyzed for the presence of the principal estrogenic chemical contaminants, estradiol, estrone, ethinylestradiol, and nonylphenol. The measured concentrations were used to predict the estrogenic activity of each effluent, employing the model of CA, based on the relative potencies of the individual chemicals in an in vitro recombinant yeast estrogen screen (rYES) and a short-term (14-day) in vivo rainbow trout vitellogenin induction assay. Based on the measured concentrations of the four chemicals in the effluents and their relative potencies in each assay, the calculated in vitro and in vivo responses compared well and ranged between 3.5 and 87 ng/L of estradiol equivalents (E2 EQ) for the different effluents. In the rYES, however, the measured E2 EQ concentrations in the effluents ranged between 0.65 and 43 ng E2 EQ/L, and they varied against those predicted by the CA model. Deviations in the estimation of the estrogenic potency of the effluents by the CA model, compared with the measured responses in the rYES, are likely to have resulted from inaccuracies associated with the measurement of the chemicals in the extracts derived from the complex effluents. Such deviations could also result as a consequence of interactions between chemicals present in the extracts that disrupted the activation of the estrogen response elements in the rYES. E2 EQ concentrations derived from the vitellogenic response in fathead minnows exposed to a series of effluent dilutions were highly comparable with the E2 EQ concentrations derived from assessments of the estrogenic potency of these dilutions in the rYES. Together these data support the use of bioassays for determining the estrogenic potency of WwTW effluents, and they highlight the associated problems for modeling approaches that are reliant on measured concentrations of estrogenic chemicals
Influence on electron coherence from quantum electromagnetic fields in the presence of conducting plates
The influence of electromagnetic vacuum fluctuations in the presence of the
perfectly conducting plate on electrons is studied with an interference
experiment. The evolution of the reduced density matrix of the electron is
derived by the method of influence functional. We find that the plate boundary
anisotropically modifies vacuum fluctuations that in turn affect the electron
coherence. The path plane of the interference is chosen either parallel or
normal to the plate. In the vicinity of the plate, we show that the coherence
between electrons due to the boundary is enhanced in the parallel
configuration, but reduced in the normal case. The presence of the second
parallel plate is found to boost these effects. The potential relation between
the amplitude change and phase shift of interference fringes is pointed out.
The finite conductivity effect on electron coherence is discussed.Comment: 29 pages, 3 figure
A Holographic Model of Strange Metals
We give a review on our recent work arXiv:1006.0779 [hep-th] and
arXiv:1006.1719 [hep-th], in which properties of holographic strange metals
were investigated. The background is chosen to be anisotropic scaling solution
in Einstein-Maxwell-Dilaton theory with a Liouville potential. The effects of
bulk Maxwell field, an extra U(1) gauge field and probe D-branes on the DC
conductivity, the DC Hall conductivity and the AC conductivity are extensively
analyzed. We classify behaviors of the conductivities according to the
parameter ranges in the bulk theory and characterize conditions when the
holographic results can reproduce experimental data.Comment: 34 pages, 15 figures, minor correction
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