394 research outputs found

    1-D Convolutional Graph Convolutional Networks for Fault Detection in Distributed Energy Systems

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    This paper presents a 1-D convolutional graph neural network for fault detection in microgrids. The combination of 1-D convolutional neural networks (1D-CNN) and graph convolutional networks (GCN) helps extract both spatial-temporal correlations from the voltage measurements in microgrids. The fault detection scheme includes fault event detection, fault type and phase classification, and fault location. There are five neural network model training to handle these tasks. Transfer learning and fine-tuning are applied to reduce training efforts. The combined recurrent graph convolutional neural networks (1D-CGCN) is compared with the traditional ANN structure on the Potsdam 13-bus microgrid dataset. The achievable accuracy of 99.27%, 98.1%, 98.75%, and 95.6% for fault detection, fault type classification, fault phase identification, and fault location respectively.Comment: arXiv admin note: text overlap with arXiv:2210.1517

    Oral Sulopenem and Tebipenem for Complicated Urinary Tract Infection and Pyelonephritis in patients with Extended-Spectrum Beta-Lactamase (ESBL)-producing Gram Negative, Susceptible Bacteria

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    ESBL-producing gram negative Enterobacteria is becoming more prevalent, and carbapenems play a key role in combating against ESBL for complicated urinary tract infections (cUTI). However, carbapenems are only available intravenously in the U.S. FDA is currently reviewing the newly developed oral carbapenems (sulopenem and tebipenem) and have requested additional clinical trial information before granting approval for cUTI. Currently available phase 3 clinical trials for tebipenem and sulopenem are reviewed

    The impact of intraspecific competition on tree growth in planted Korean pine forest

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    The aim of this study was to explore the correlation of competition indices (CIs) on individual tree growth for Korean pine (Pinus koraiensis) plantation using partial correlation analysis and generalized linear models. The data were collected from 15 permanent plots in Mengjiagang forestry farm, Northeast China. The results showed that the distance dependent CIs have a higher predictive capacity for individual growth of pine trees. The control index of competitive trees number (CI1) combined with the selection fixed competitor trees (M2) was found to be the most well correlated competition measure with five - years diameter increment. Thus, the competition index (CI1- M2) was recommended for developing individual tree growth models. The subject tree diameter at breast height, crown width, height to crown base, tree volume and basal area all showed a significantly linear correlation with tree competition intensity (P 0,05). Diameter at breast height, crown width, tree volume and basal area all decreased with increasing competition intensity, whereas the height to crown base increased. There was no significant relationship between competition intensity and tree height (P 0,05). The optimal model of predicting individual growth with logarithm of diameter at breast height and CIs as the independent variables due to the best fitting performance. This results also showed considerable improvement in predicting individual tree periodic growth when including competition indices that the mean absolute error is reduced in the range of 22−25%.

    Perception of having children through surrogacy in individuals with MRKH in Vietnam: a qualitative study

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    IntroductionMayer-Rokitansky-Küster-Hauser syndrome (MRKH) is rare condition that has a negative impact on quality of life because affected women lack a uterus and vagina, and are therefore unable to engage in sexual intercourse and experience natural pregnancy. This study evaluated perceptions of surrogacy in Vietnamese women with MRKH who have started families.MethodWomen with MRKH who had undergone successful vaginal reconstruction, were married, and had started families participated in a semi-structured, in-depth, one-on-one online video interview with an experienced female psychologist. Open-ended questions were used to encourage participants to express their perceptions of surrogacy; prominent themes were discussed, compared, and combined.ResultsTwenty women (mean age 31 years) agreed to participate. Key themes identified from interviews were the importance of having genetic offspring, consideration of surrogacy as a preferred solution to infertility, the barriers to surrogacy in Vietnam, lack of reproductive information and counselling, individuals concealing their health condition, the impact of religion on the possibility of surrogacy, the economic cost of surrogacy, and the difficulty in finding a surrogate under the restrictions imposed by Vietnamese law.DiscussionBased on the perceptions of women from MRKH from Vietnam, there is an opportunity to improve how infertility is managed in these people, including information about surrogacy. These data show that individuals with MRKH should be provided with information about the possibility of surrogacy, encouraged to be open and seek support, and be managed by a multidisciplinary team that includes psychological support; the provision of economic support for fertility treatments in women with MRKH should also be considered

    Seasonal variation of phytoplankton in My Thanh River, Mekong delta, Vietnam

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    A study on the seasonal variation of phytoplankton composition was conducted at the upper, middle, and lower parts of the My Thanh River, which supplies an important source of water for aquaculture. Qualitative and quantitative samples of phytoplankton were collected monthly at both high and low tide. The results showed that a total of 171 phytoplankton (algae) species were recorded, belonging to 59 genera and 5 phyla. Diatoms were the most abundant group with the highest species number, followed by green algae. The other phyla possessed a lower number of species. The species composition was more diverse in the rainy season and at high tide at most of the sampling sites. The mean density of algae varied from 30,900-43,521 ind.L^-1^. The density of diatoms was higher in the middle and lower parts. At the same time, euglenoids displayed the highest density in the upper part, showing a difference in the dominant algae group under the influence of salinity. Salinity was found to be significantly positively correlated (p<0.01) with diatoms, whereas it was negatively correlated (p<0.05) with blue-green algae and euglenoids. The algae composition was quite diverse, with the H' index ranging from 2.0-3.3, showing the water quality was slightly to moderately polluted

    Assessment of the Effectiveness of Ich Tam Khang as a Supportive Therapy for Chronic Heart Failure

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    Background: Heart failure is a chronic disease needing lifelong management. Despite the advances that have been made in the treatment of the disease, both the longevity and quality of life for those with chronic heart failure remain impaired. A more effective therapeutic approach with less negative side effects is still needed. In this study, we evaluate Ich Tam Khang (ITK), the poly-ingredient herbal and nutritional preparation with multiple physiological actions, as a supportive therapy for patients with chronic heart failure.Aims of Study: To evaluate the effectiveness and safety of Ich Tam Khang as an adjunctive treatment of chronic heart failure.Methods: A total of 60 patients with chronic congestive heart failure were enrolled in this open label, cross-sectional and prospective study. All patients were treated with a conventional regimen (digoxin, diuretics, angiotensin-converting-enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs), beta blockers) for at least 4 weeks before being divided into two equal groups. In the treated patients with ITK, patients received conventional therapy plus 4 tablets ITK per day added in two divided doses. In the control patients, all patients kept the same conventional regimen without ITK. All patients were followed up for 3 months for clinical and para-clinical outcomes.Result: The symptoms of heart failure (dyspnea, palpitation, peripheral edema, neck vein distention, heptojugular reflex) decreased. Heart rate and blood pressure stabilized during treatment in the treated patients with ITK. Additionally, total cholesterol and HDL-cholesterol normalized in the patients treated with ITK. Most of echocardiography parameters in the ITK treated patients were superior to the control patients. ITK is safe and it has no side effects.Conclusion: ITK as a combination of herbal and nutritional preparation is effective in reducing heart failure symptoms, improving patient's quality of life for the patients with decompensated heart failure and reducing total cholesterol and LDL-C

    Specific xylan activity revealed for AA9 Lytic Polysaccharide Monooxygenases of the thermophilic fungus Malbranchea cinnamomea by functional characterization

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    The thermophilic biomass-degrader\ua0Malbranchea cinnamomea\ua0exhibits poor growth on cellulose but excellent growth on hemicelluloses as the sole carbon source. This is surprising considering that its genome encodes eight lytic polysaccharide monooxygenases (LPMOs) from auxiliary activity family 9 (AA9), enzymes known for their high potential in accelerating cellulose depolymerization. We characterized four of the eight (M. cinnamomea\ua0AA9s)\ua0McAA9s, namely,\ua0McAA9A,\ua0McAA9B,\ua0McAA9F, and\ua0McAA9H, to gain a deeper understanding about their roles in the fungus. The characterized\ua0McAA9s were active on hemicelluloses, including xylan, glucomannan, and xyloglucan, and furthermore, in accordance with transcriptomics data, differed in substrate specificity. Of the\ua0McAA9s,\ua0McAA9H is unique, as it preferentially cleaves residual xylan in phosphoric acid-swollen cellulose (PASC). Moreover, when exposed to cellulose-xylan blends,\ua0McAA9H shows a preference for xylan and for releasing (oxidized) xylooligosaccharides. The cellulose dependence of the xylan activity suggests that a flat conformation, with rigidity similar to that of cellulose microfibrils, is a prerequisite for productive interaction between xylan and the catalytic surface of the LPMO.\ua0McAA9H showed a similar trend on xyloglucan, underpinning the suggestion that LPMO activity on hemicelluloses strongly depends on the polymers’ physicochemical context and conformation. Our results support the notion that LPMO multiplicity in fungal genomes relates to the large variety of copolymeric polysaccharide arrangements occurring in the plant cell wall

    The Waldschmidt constant for squarefree monomial ideals

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    Given a squarefree monomial ideal IR=k[x1,,xn]I \subseteq R =k[x_1,\ldots,x_n], we show that α^(I)\widehat\alpha(I), the Waldschmidt constant of II, can be expressed as the optimal solution to a linear program constructed from the primary decomposition of II. By applying results from fractional graph theory, we can then express α^(I)\widehat\alpha(I) in terms of the fractional chromatic number of a hypergraph also constructed from the primary decomposition of II. Moreover, expressing α^(I)\widehat\alpha(I) as the solution to a linear program enables us to prove a Chudnovsky-like lower bound on α^(I)\widehat\alpha(I), thus verifying a conjecture of Cooper-Embree-H\`a-Hoefel for monomial ideals in the squarefree case. As an application, we compute the Waldschmidt constant and the resurgence for some families of squarefree monomial ideals. For example, we determine both constants for unions of general linear subspaces of Pn\mathbb{P}^n with few components compared to nn, and we find the Waldschmidt constant for the Stanley-Reisner ideal of a uniform matroid.Comment: 26 pages. This project was started at the Mathematisches Forschungsinstitut Oberwolfach (MFO) as part of the mini-workshop "Ideals of Linear Subspaces, Their Symbolic Powers and Waring Problems" held in February 2015. Comments are welcome. Revised version corrects some typos, updates the references, and clarifies some hypotheses. To appear in the Journal of Algebraic Combinatoric
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